Whats the diagnoses and the medication
Per Andrews' Diseases of the Skin: Nickel in jewelry produces allergic contact dermatitis. Treatment consists of topical corticosteroids. Sweat worsens the reaction, as perspiration can leach nickel from metal.
| Medication | Use |
|---|---|
| Hydrocortisone 1% cream (OTC) | Apply to affected area 2x/day for mild cases |
| Triamcinolone 0.1% cream (Rx) | For moderate cases, apply 2x/day |
| Oral antihistamine (e.g., cetirizine 10 mg daily, or loratadine 10 mg daily) | Relieve itching |
| Medication | Use |
|---|---|
| Hydrocortisone 1% cream (OTC) | Apply to each bite 2-3x/day for itch/inflammation |
| Calamine lotion (OTC) | Soothing, apply as needed |
| Cetirizine 10 mg or Loratadine 10 mg (OTC antihistamine) | Once daily for itch relief |
| Diphenhydramine (Benadryl) 25-50 mg | At bedtime if itching disrupts sleep |
This type lesions arw throughout the body face neck arm what will be diagnosis
Per Tintinalli's Emergency Medicine: "Pruritic papules, secondary excoriations, and burrows are classic findings... The head and neck are typically spared, although they may be involved in infants and the immunocompromised."
Per Red Book 2021: "Primary varicella manifests as a generalized, pruritic, erythematous vesicular rash typically consisting of 250 to 500 lesions in varying stages of development (papules, vesicles) and resolution (crusting), low-grade fever."
| Treatment | Details |
|---|---|
| Permethrin 5% cream (1st line) | Apply head-to-toe (including face/scalp in children and infants), leave on 8-12 hours, then wash off. Repeat in 1 week. |
| Oral Ivermectin 200 mcg/kg (alternative/add-on) | Single dose, repeated after 7-10 days. Used if topical fails or in widespread/crusted cases. |
| Triamcinolone 0.1% cream | For residual itch after treatment (dead mites still cause itch for weeks) |
| Oral antihistamine (cetirizine or loratadine 10 mg) | For itch relief during and after treatment |
| Wash all linens/clothing in hot water | All bedding, towels, and clothing must be washed in hot water and machine-dried. Items that cannot be washed should be sealed in plastic bags for 10 days. |
| Treat all household contacts | Everyone in the home must be treated simultaneously, even if not yet symptomatic |
Source: Tintinalli's Emergency Medicine and Red Book 2021
| Treatment | Details |
|---|---|
| Acyclovir 800 mg 5x/day for 5 days (adults) | Start within 24 hours of rash onset for best effect |
| Acyclovir 20 mg/kg 4x/day (children, max 800 mg/dose) | Oral for 5 days |
| Calamine lotion | Topical soothing for itch |
| Oral antihistamine (diphenhydramine or cetirizine) | For itching |
| Paracetamol/Acetaminophen | For fever (do NOT use aspirin in children - risk of Reye syndrome) |
| Isolation | Avoid contact with others until all lesions are fully crusted over |
Chickenpox if two types
"Varicella is the acute disease that follows primary contact with the virus."
- Jawetz Medical Microbiology
| Feature | Details |
|---|---|
| Incubation | 10-21 days after exposure |
| First symptoms | Fever, malaise, loss of appetite |
| Rash pattern | Starts on trunk, then spreads to face, arms, legs, mouth |
| Lesion stages | All stages visible at the SAME time: macules → papules → vesicles (fluid blisters) → crusts |
| Number of lesions | 250-500 lesions typically |
| Itch | Intensely itchy |
| Duration | Rash lasts about 5-7 days |
"Zoster is the response of the partially immune host to reactivation of varicella virus present in latent form in neurons in sensory ganglia."
- Jawetz Medical Microbiology
| Feature | Details |
|---|---|
| Pain BEFORE rash | Burning, tingling, shooting pain in a strip of skin - often days before any rash appears |
| Rash pattern | One-sided (unilateral), in a band or stripe following one nerve (dermatomal) - does NOT cross the midline |
| Location | Most common on chest/back, but can affect face (eye - very dangerous), neck, limbs |
| Lesions | Clusters of vesicles (blisters) on red base - same as chickenpox but localized |
| Pain | Often severe, burning pain during and after the rash |
| After-effect | Post-herpetic neuralgia - nerve pain lasting weeks to months after rash heals |
| Feature | Varicella (Type 1) | Herpes Zoster (Type 2) |
|---|---|---|
| Cause | First-time VZV infection | Reactivation of old VZV |
| Age | Children (mainly) | Elderly / immunocompromised |
| Distribution | Widespread, all over body | One-sided stripe, one dermatome |
| Face involvement | Yes | Only if trigeminal nerve affected |
| Pain | Mild itch | Severe burning/shooting pain |
| Contagious | Highly contagious | Mildly contagious (only from direct blister contact) |
| Fever | Yes (low-grade) | Usually no |
| Recurrence | Only once (then becomes zoster) | Can recur in immunocompromised |
| Drug | Dose |
|---|---|
| Acyclovir (adults/severe cases) | 800 mg orally 5x/day for 5 days |
| Acyclovir (immunocompromised, IV) | 10 mg/kg every 8 hours for 7-10 days |
| Valacyclovir (adults, preferred) | 1 g three times daily for 5 days |
| Valacyclovir (children 2-18 yrs) | 20 mg/kg 3x/day, max 1 g/dose |
| Antihistamine (cetirizine/loratadine) | For itch |
| Paracetamol | For fever - NO aspirin in children (Reye syndrome risk) |
| Calamine lotion | Topical itch relief |
Note: Acyclovir is NOT recommended for otherwise healthy children with mild chickenpox - only symptomatic treatment needed.
| Drug | Dose |
|---|---|
| Valacyclovir (preferred) | 1 g three times daily for 7 days |
| Famciclovir | 500 mg three times daily for 7 days |
| Acyclovir | 800 mg 5x/day for 7 days (less preferred) |
| Prednisone (for severe pain, age >50) | 60 mg/day tapering over 21 days |
| Gabapentin (for post-herpetic neuralgia) | 300 mg at bedtime, up to 1200 mg 3x/day |
| Pregabalin | 75 mg at bedtime, up to 300 mg twice daily |
| Lidocaine patches / Capsaicin cream | For localized nerve pain |
Start antivirals within 72 hours of rash onset for best effect.
- Goldman-Cecil Medicine
| Vaccine | For |
|---|---|
| Varicella vaccine (live attenuated) | Children - prevents chickenpox |
| Shingrix (recombinant, preferred) | Adults 50+ - prevents shingles and post-herpetic neuralgia |
| Zostavax (live attenuated, older) | Adults 60+ (less effective than Shingrix) |