I now have enough high-quality evidence to give a thorough, well-cited answer. Here is the complete response:
TENS vs. Ultrasound (US) Therapy in Frozen Shoulder with Tenderness
Short Answer
When tenderness is the predominant feature, TENS is preferred for immediate pain/tenderness relief, but if the goal is to address the underlying adhesive capsulitis (restricted ROM, fibrosis), neither modality has strong evidence - and both should be combined with exercise therapy. Here is the breakdown:
What Each Modality Does
| Feature | TENS | Therapeutic Ultrasound (US) |
|---|
| Primary mechanism | Pain gate-control (spinal) + endorphin release | Thermal + cavitation - penetrates deep tissue |
| Depth of action | Superficial - nerve/skin level | Deep tissue (capsule, ligament level) |
| Effect on fibrosis | None | Mechanical effect on collagen cross-links |
| Effect on tenderness | Direct and fast - raises pain threshold | Indirect (via reducing inflammation/fibrosis) |
| ROM improvement | Minimal | Moderate (with concurrent exercise) |
| Inflammation | No direct effect | Pulsed US reduces sub-acute inflammation |
For Tenderness Specifically
Frozen shoulder tenderness arises from:
- Capsular inflammation (synovitis, especially in the freezing phase)
- Secondary muscle spasm and guarding
- Peripheral sensitization
TENS directly addresses all three by:
- Gate control - closes pain gates at the spinal dorsal horn (A-beta fibers suppress C-fiber input)
- Opioid release - high-frequency TENS (80-100 Hz) releases enkephalins; low-frequency (1-5 Hz) releases beta-endorphins
- Muscle relaxation - reduces secondary spasm around a tender joint
In the acute/freezing phase where tenderness is prominent, TENS provides faster and more targeted analgesia. It is also safer over inflamed or highly tender tissue compared to continuous US (which generates heat and can aggravate acute inflammation).
Pulsed (non-thermal) US is suitable even over inflamed tissue but acts more slowly and its primary benefit is structural (facilitating tissue extensibility).
What the Evidence Says
A 2024
systematic review and meta-analysis (Brindisino et al.,
Disability and Rehabilitation;
PMID 37667875) analyzed 23 RCTs (1073 patients) on electrophysical agents in frozen shoulder:
"Ultrasound therapy did not yield significant differences in any outcomes" - including pain, ROM, and disability.
ESWT and laser showed potentially clinically significant differences in pain, but certainty of evidence was very low.
Conclusion: US therapy is NOT recommended for frozen shoulder based on current evidence.
There are currently no high-quality RCTs showing TENS is superior to US for frozen shoulder either, but the physiological rationale strongly favors TENS for the tenderness/pain component.
Regarding Harrison's Principles (2025): Physical therapy forms the foundation of treatment, with NSAIDs and local glucocorticoid injections as adjuncts. Neither TENS nor US is specifically recommended as a first-line standalone modality.
Clinical Recommendation
| Clinical goal | Preferred modality |
|---|
| Reduce tenderness / acute pain | TENS |
| Reduce muscle spasm | TENS |
| Improve tissue extensibility (chronic/frozen phase) | Pulsed US (limited evidence) |
| Improve ROM | Exercise therapy (both are adjuncts only) |
Best practice: Use TENS for pain and tenderness control, then follow immediately with stretching/mobilization exercises. US may be added in the chronic phase (frozen or thawing) to improve tissue compliance before exercise. Neither replaces manual therapy and exercise as the core intervention.
Key caveat: The 2024 meta-analysis (
PMID 37667875) found the overall certainty of evidence for all electrophysical agents in frozen shoulder is
very low, so clinical judgment and patient response should guide modality selection.