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PSM Answers - Q.P. 6


Q1. Objectives of Reproductive and Child Health (RCH) Programme + NHM Initiatives to Reduce Mortality Among Mothers and Children (2+8 = 10 Marks)

Part A: Objectives of RCH Programme (2 marks)

The RCH programme was launched in 1997, replacing the earlier Child Survival and Safe Motherhood (CSSM) programme. It adopts a life-cycle approach to health.
Objectives:
  1. Reduce infant mortality, under-5 mortality, and maternal mortality
  2. Achieve replacement level fertility (NRR = 1)
  3. Promote responsible and planned parenthood
  4. Ensure universal access to contraception and safe abortion services
  5. Provide quality antenatal, intranatal, and postnatal care
  6. Reduce incidence of RTIs/STIs/HIV
  7. Promote full immunization of children and pregnant women
  8. Improve nutritional status of mothers and children

Part B: NHM Initiatives to Reduce Mortality Among Mothers and Children (8 marks)

The National Health Mission (NHM) was launched in 2013 (combining NRHM 2005 + NUHM). Key initiatives:

A. Janani Suraksha Yojana (JSY)

  • Cash incentive scheme to promote institutional deliveries
  • Targets BPL women, SC/ST women, and women in LPS states
  • Cash benefit: Rs. 1400 (rural LPS), Rs. 600 (urban LPS)
  • ASHA acts as link worker

B. Janani Shishu Suraksha Karyakram (JSSK)

  • Free and cashless delivery, C-section, and newborn care at government facilities
  • Free drugs, diagnostics, blood, transport, diet for mother and sick newborn
  • Eliminates out-of-pocket expenditure

C. Pradhan Mantri Surakshit Matritva Abhiyan (PMSMA)

  • Fixed day antenatal care on the 9th of every month
  • Minimum package of ANC provided to all pregnant women in 2nd/3rd trimester
  • Identification of high-risk pregnancies

D. LaQshya (Labour Room Quality Improvement Initiative)

  • Improves quality of care in labour rooms and maternity operation theatres
  • Aims to reduce preventable maternal and newborn deaths

E. Navjaat Shishu Suraksha Karyakram (NSSK)

  • Training of health workers in basic newborn care and resuscitation
  • Special Newborn Care Units (SNCUs), Newborn Stabilization Units (NBSUs), Newborn Care Corners (NBCCs)

F. Home Based Newborn Care (HBNC)

  • ASHA visits newborn at home (6 visits in first 42 days)
  • Promotes early initiation of breastfeeding, skin-to-skin care, cord care

G. Rashtriya Bal Swasthya Karyakram (RBSK)

  • Child Health Screening for 4 Ds: Defects at birth, Deficiencies, Diseases, Developmental delays
  • Mobile health teams screen children 0-18 years

H. Mission Indradhanush

  • Intensified immunization drive to cover unvaccinated/partially vaccinated children under 2 years and pregnant women
  • Targets reaching 90% full immunization coverage

I. Integrated Management of Neonatal and Childhood Illness (IMNCI)

  • Strategy for managing common childhood illnesses (pneumonia, diarrhoea, malaria, malnutrition)

J. Reproductive, Maternal, Newborn, Child and Adolescent Health (RMNCH+A)

  • Comprehensive strategy linking all stages of the life cycle
  • Emphasizes continuum of care from pre-pregnancy to adolescence

Q2. Factors for Rising Trend of Cancer + Strategies for Control with Reference to Tobacco (10 Marks)

Factors Responsible for Rising Trend of Cancer:

Host Factors:
  • Age (most cancers increase with age; aging population)
  • Genetic predisposition (BRCA1/2, APC gene mutations)
  • Hormonal factors (estrogen in breast/endometrial cancer)
  • Immunosuppression
  • Pre-cancerous lesions (leukoplakia, erythroplakia)
Environmental/Behavioural Factors:
  1. Tobacco use - single largest cause (30% of all cancers); smoking causes lung, oral, laryngeal, esophageal, bladder cancer; tobacco chewing causes oral cancer
  2. Alcohol - associated with oral, esophageal, liver, breast cancers
  3. Dietary factors - low fibre, high fat diet, red meat, preserved foods (nitrosamines), aflatoxins
  4. Occupational carcinogens - asbestos (mesothelioma), benzene (leukemia), vinyl chloride, arsenic
  5. Radiation - ionizing (X-ray, nuclear) and UV radiation (skin cancer)
  6. Infections - HPV (cervical cancer), HBV/HCV (liver cancer), H. pylori (gastric), EBV (lymphoma), HIV
  7. Reproductive factors - early menarche, late menopause, nulliparity (breast/ovarian)
  8. Urbanization and lifestyle changes - sedentary behavior, obesity
  9. Aging population - India's demographic transition
  10. Improved diagnosis and reporting - apparent rise due to better detection

Strategies for Control of Cancer with Reference to Tobacco:

National Cancer Control Programme (NCCP) - launched 1975, revised 1984, 2004-05:

1. Primary Prevention (Tobacco Control)

  • COTPA (Cigarettes and Other Tobacco Products Act), 2003:
    • Prohibition of smoking in public places
    • Ban on advertisement and promotion of tobacco products
    • Mandatory pictorial warnings on tobacco packages (85% of pack surface)
    • Ban on sale to minors (under 18 years)
    • No sale within 100 meters of educational institutions
  • MPOWER package (WHO Framework Convention on Tobacco Control - FCTC):
    • Monitor tobacco use and prevention policies
    • Protect people from tobacco smoke (smoke-free legislation)
    • Offer help to quit tobacco use (cessation services - iQuitline 1800-11-2356)
    • Warn about dangers of tobacco (health warnings, mass media)
    • Enforce bans on advertising, promotion, and sponsorship
    • Raise taxes on tobacco
  • National Tobacco Control Programme (NTCP) - launched 2007-08

2. Secondary Prevention (Early Detection)

  • Population-based screening for oral, cervical, and breast cancer (under NPCDCS)
  • Visual Inspection with Acetic Acid (VIA) for cervical cancer
  • FNAC, biopsy for diagnosis
  • Cancer screening at Health and Wellness Centres

3. Tertiary Prevention

  • Treatment: surgery, radiotherapy, chemotherapy
  • Regional Cancer Centres (RCCs) - 28 across India
  • Pain relief and palliative care

4. Cancer Registry

  • Population-based and hospital-based cancer registries
  • National Cancer Registry Programme (NCRP) under ICMR

Q3. Causes of Occupational Cancer (5 Marks)

Occupational cancers account for approximately 4-5% of all cancers.
CarcinogenOccupation/ExposureCancer Type
AsbestosMining, insulation workersMesothelioma, lung cancer
BenzenePetroleum, rubber industryLeukemia
Aromatic amines (2-naphthylamine, benzidine)Dye, rubber, leather workersBladder cancer
Vinyl chloridePVC manufacturingAngiosarcoma of liver
ArsenicSmelting, pesticide workersSkin, lung cancer
Chromium (hexavalent)Electroplating, steel industryLung, nasal cancer
NickelNickel refiningNasal, lung cancer
Ionizing radiationX-ray technicians, nuclear workersLeukemia, thyroid, skin
Hardwood dustCarpenters, furniture makersNasal adenocarcinoma
Coal tar, sootChimney sweeps, gas workersScrotal, skin cancer (1st occupational cancer described by Percivall Pott, 1775)
AflatoxinGrain storage workersHepatocellular carcinoma
Prevention: Substitution of carcinogens, engineering controls, PPE, biological monitoring, pre-employment and periodic medical examination, worker education.

Q4. Vaccine Schedule in UIP for Under-Five (5 Marks)

The Universal Immunization Programme (UIP) was launched in 1985.
AgeVaccineRoute/Site
BirthBCGIntradermal, left arm
BirthOPV-0 (Zero dose)Oral
BirthHepatitis B - 0IM, anterolateral thigh
6 weeksOPV-1, Pentavalent-1 (DPT+Hib+HepB), IPV-1, Rotavirus-1, PCV-1
10 weeksOPV-2, Pentavalent-2, Rotavirus-2, PCV-2
14 weeksOPV-3, Pentavalent-3, IPV-2, Rotavirus-3, PCV-3
9-12 monthsMeasles-Rubella (MR-1), JE-1 (endemic areas)SC, right upper arm
9-12 monthsVitamin A - 1st dose (1 lakh IU)Oral
16-24 monthsDPT booster-1, OPV booster, MR-2, JE-2, Vitamin A - 2nd dose
5-6 yearsDPT booster-2
Note: PCV = Pneumococcal conjugate vaccine (added 2017); Rotavirus vaccine (added 2016-19 phased); IPV introduced in 2015.

Q5. Disaster Cycle (5 Marks)

The Disaster Cycle (also called Disaster Management Cycle) consists of 4 phases:

1. Mitigation Phase (Pre-disaster)

  • Activities that prevent disasters or reduce their effects
  • Examples: Building codes, land-use planning, flood embankments, early warning systems, vulnerability mapping
  • Goal: Reduce risk

2. Preparedness Phase (Pre-disaster)

  • Activities that improve ability to respond to disasters
  • Examples: Training emergency personnel, stockpiling supplies, developing emergency plans, community education, mock drills, establishing early warning systems
  • Goal: Reduce impact

3. Response Phase (During/Immediately after disaster)

  • Immediate actions to save lives and meet basic needs
  • Examples: Search and rescue, emergency medical care, evacuation, food/water/shelter provision, disease surveillance
  • Sub-phases: Heroic phase, Honeymoon phase, Disillusionment phase
  • Goal: Save lives, reduce suffering

4. Recovery Phase (Post-disaster)

  • Actions to restore normalcy
  • Short-term recovery: Debris removal, restoration of services, temporary housing
  • Long-term recovery (Rehabilitation/Reconstruction): Rebuilding infrastructure, psychosocial support, livelihood restoration
  • Goal: Restore and improve pre-disaster conditions
Mitigation → Preparedness → Response → Recovery → (back to Mitigation)
This is a continuous cycle; lessons from each phase inform the next.

Q6. Self-Care in Diabetes Mellitus (5 Marks)

Self-care is central to diabetes management. The 7 self-care behaviours (AADE-7):

1. Healthy Eating

  • Calorie-controlled, low glycaemic index diet
  • Restriction of refined carbohydrates, saturated fats, trans fats
  • Increase dietary fibre (vegetables, whole grains)
  • Regular meal timings; avoid skipping meals

2. Being Active (Physical Activity)

  • Minimum 150 minutes/week of moderate aerobic exercise
  • Resistance training 2-3 times/week
  • Reduces insulin resistance, promotes weight loss, improves glycaemic control

3. Monitoring

  • Self-Monitoring of Blood Glucose (SMBG): Regular finger-prick testing
  • Monitoring HbA1c every 3 months (target <7%)
  • Daily foot inspection

4. Taking Medications

  • Adherence to oral hypoglycaemic agents or insulin as prescribed
  • Understanding signs of hypoglycaemia and its management (15-15 rule)

5. Problem Solving

  • Recognizing and managing hypoglycaemia, hyperglycaemia, sick day management

6. Healthy Coping

  • Managing diabetes-related distress and depression
  • Support groups, stress management techniques

7. Reducing Risks (Foot Care + Complication Prevention)

  • Daily foot inspection, proper footwear (no barefoot walking)
  • Regular eye examination (for retinopathy), annual kidney function tests
  • Blood pressure control (<130/80 mmHg)
  • Lipid control, smoking cessation
  • Dental hygiene

Q7. Cancer Registry (5 Marks)

A cancer registry is an information system designed for the collection, storage, management, and analysis of data on persons with cancer.

Types:

1. Hospital-Based Cancer Registry (HBCR)
  • Maintains data on all cancer patients treated in a specific hospital
  • Used for clinical management, treatment outcomes, survival analysis
  • Does not give incidence rates for the general population
2. Population-Based Cancer Registry (PBCR)
  • Collects data on all new cancer cases occurring in a defined geographic population
  • Used to calculate cancer incidence, mortality, prevalence rates
  • Provides epidemiological data for planning and policy

In India - National Cancer Registry Programme (NCRP):

  • Established by ICMR in 1981
  • Currently 30+ PBCRs and several HBCRs
  • Major PBCRs: Bangalore, Mumbai, Chennai, Delhi, Bhopal, Dibrugarh
  • Publishes data in "Cancer Incidence in Five Continents" (IARC/GLOBOCAN)

Uses of Cancer Registry:

  1. Measure the burden of cancer (incidence, prevalence, mortality)
  2. Identify high-risk groups and geographic clusters
  3. Monitor cancer trends over time
  4. Evaluate screening and prevention programmes
  5. Provide data for research and clinical trials
  6. Resource allocation and policy planning

Data Collected:

  • Patient demographics (age, sex, address)
  • Site and histological type of cancer (ICD-10 codes)
  • Date of diagnosis, stage at diagnosis
  • Treatment details and survival outcomes

Q8. Principles of Primary Health Care (5 Marks)

Primary Health Care (PHC) was defined at the Alma-Ata Declaration, 1978 as "essential health care based on practical, scientifically sound and socially acceptable methods and technology made universally accessible to individuals and families in the community."

The 8 Essential Components (Mnemonic: FEATS MCE):

  1. Food supply and proper nutrition
  2. Education about prevailing health problems
  3. Adequate safe water and basic sanitation
  4. Treatment of common diseases and injuries
  5. Safe motherhood and family planning (MCH + FP)
  6. Maternal and child health
  7. Control of endemic diseases
  8. Essential drugs supply + EPI (immunization)

5 Principles of PHC (Alma-Ata):

  1. Equitable distribution - services accessible to all, especially underserved
  2. Community participation - involvement of community in planning and implementation
  3. Intersectoral coordination - collaboration between health, agriculture, education, water, sanitation sectors
  4. Appropriate technology - affordable, acceptable, scientifically sound methods
  5. Multi-level approach - linkage between primary, secondary, and tertiary care
India's PHC Structure:
  • Sub-centre: covers 3000-5000 (plain) / 1000-3000 (hilly) population
  • PHC: covers 20,000-30,000 (plain) / 3,000-5,000 (hilly) population
  • Community Health Centre (CHC): covers 80,000-1,20,000 population

Q9. Iodine Deficiency Disorders (IDD) (5 Marks)

IDD refers to the spectrum of disorders caused by inadequate iodine intake.

Magnitude: ~200 million people at risk in India; goitre belt = sub-Himalayan region.

Consequences of Iodine Deficiency (by life stage):

StageDisorder
FetusCretinism, stillbirth, congenital anomalies, increased perinatal mortality
NeonateNeonatal goitre, neonatal hypothyroidism, increased infant mortality
Child/AdolescentGoitre, hypothyroidism, impaired mental function, retarded growth
AdultGoitre, hypothyroidism, impaired mental function, reduced fertility
Cretinism - most severe form: irreversible mental retardation, deaf-mutism, spastic diplegia, short stature.

Daily Iodine Requirements:

  • Children: 90-120 mcg/day
  • Adults: 150 mcg/day
  • Pregnant/lactating women: 200-250 mcg/day

National Iodine Deficiency Disorders Control Programme (NIDDCP):

  • Formerly National Goitre Control Programme (1962)
  • Renamed NIDDCP in 1992
  • Universal Salt Iodization (USI) - iodization of all edible salt at 15 ppm at consumer level
  • Iodized salt contains potassium iodate (KIO3) added at 30 ppm at production level
  • Ban on sale of non-iodized salt for human consumption
  • Sentinel surveillance and IDD surveys

Diagnosis: Urinary iodine excretion (UIE) - median UIE <100 mcg/L indicates deficiency


Q10. Hormonal Contraception (5 Marks)

Hormonal contraceptives contain synthetic estrogen (ethinyl estradiol) and/or progestogen.

Types:

A. Combined Oral Contraceptive Pills (COCPs)

  • Contain estrogen + progestogen
  • Mechanism: Inhibit ovulation (primary), thicken cervical mucus, alter endometrium
  • Efficacy: Pearl Index = 0.1-0.3 (perfect use)
  • Types: Monophasic, biphasic, triphasic
  • Examples: Mala-D (govt.), Mala-N (low-dose), Saheli (centchroman - non-steroidal, weekly pill)
  • Contraindications: Thromboembolic disease, breast cancer, liver disease, smokers >35 years, uncontrolled hypertension, pregnancy

B. Progestogen-Only Pills (Mini-pills)

  • Suitable for lactating mothers (no estrogen to suppress lactation)
  • Example: Centchroman (Saheli) - taken weekly

C. Injectable Contraceptives

  • Depot Medroxyprogesterone Acetate (DMPA/Depo-Provera): 150 mg IM every 3 months
  • MPA (Antara programme in India): 3-monthly injection introduced under FP programme
  • Noristerat: 200 mg IM every 2 months

D. Implants (Subdermal)

  • Levonorgestrel (Norplant/Jadelle): 5 years protection
  • Etonogestrel (Implanon): 3 years

E. Intrauterine System (IUS)

  • Levonorgestrel-IUS (Mirena): 5 years; reduces menstrual blood loss

F. Emergency Contraception

  • Levonorgestrel 1.5 mg (i-pill) within 72 hours
  • Ulipristal acetate within 120 hours
  • Cu-IUD within 120 hours (most effective EC)

Non-contraceptive benefits of COCPs:

  • Reduced risk of ovarian and endometrial cancer
  • Treatment of dysmenorrhoea, endometriosis, PCOS
  • Reduced PID risk

Q11. Pasteurization of Milk (2-3 Marks)

Pasteurization is the process of heating milk to destroy pathogenic organisms without significantly altering its nutritive value or taste.

Methods:

  1. HTST (High Temperature Short Time) / Flash method: 72°C for 15 seconds - most common commercial method
  2. LTLT (Low Temperature Long Time) / Holder method: 63°C for 30 minutes
  3. UHT (Ultra High Temperature): 135-150°C for 2-4 seconds - sterilization, not just pasteurization; shelf-stable for 3-6 months

Phosphatase Test: Used to confirm adequate pasteurization (alkaline phosphatase enzyme destroyed at pasteurization temperatures). A positive phosphatase test = inadequately pasteurized milk.

Pathogens destroyed: M. tuberculosis (test organism - most heat resistant pathogen of public health significance), Brucella, Salmonella, Listeria, Campylobacter, E. coli O157:H7.


Q12. Balanced Diet (2-3 Marks)

A balanced diet is one that provides all essential nutrients (macronutrients and micronutrients) in adequate amounts and correct proportions to maintain optimal health.

Components:

  • Macronutrients: Carbohydrates (55-60% of total calories), Proteins (10-15%), Fats (25-30%)
  • Micronutrients: Vitamins (fat-soluble: A, D, E, K; water-soluble: B-complex, C), Minerals (Ca, Fe, Zn, I)
  • Dietary fibre: 25-30 g/day
  • Water: 2-3 litres/day

ICMR Recommended Dietary Allowances (RDA) for a reference adult Indian man (60 kg, moderate work):

  • Energy: 2730 kcal/day
  • Protein: 60 g/day (1 g/kg/day)
  • Fat: minimum 20 g/day

Food Groups (ICMR's 5 food groups):

  1. Cereals and millets
  2. Pulses and legumes
  3. Milk and milk products
  4. Fruits and vegetables
  5. Fats and oils
ICMR's "My Plate" concept: Half the plate = fruits and vegetables; quarter = cereals; quarter = protein foods.

Q13. Panel Discussion (2-3 Marks)

Panel discussion is a health education method used for groups.

Definition:

A structured discussion by a selected group of 4-8 experts/resource persons who discuss a topic from different perspectives before an audience, followed by audience participation.

Characteristics:

  • Moderator/chairperson guides the discussion
  • Panelists have different viewpoints or areas of expertise
  • Audience can ask questions at the end
  • Size of audience: 20-100 or more

Advantages:

  • Presents multiple perspectives on a topic
  • Audience exposed to expert opinions
  • Stimulates thought and discussion
  • Good for controversial/complex topics

Disadvantages:

  • One-way communication mostly
  • Dominance by one panelist possible
  • Needs skilled moderator
  • May confuse audience with conflicting views

Uses in Health Education:

  • Community meetings on health issues (e.g., vaccine hesitancy, HIV stigma)
  • Medical/public health conferences

Q14. Vitamin A Prophylaxis (2-3 Marks)

Vitamin A Prophylaxis is the administration of high-dose Vitamin A supplements to prevent Vitamin A Deficiency (VAD) and associated complications.

National Programme for Prevention of Nutritional Blindness due to Vitamin A Deficiency:

Schedule (under UIP/RBSK):
AgeDoseRoute
9-12 months (with MR-1)1,00,000 IUOral
16-18 months (with DPT booster)2,00,000 IUOral
Every 6 months from 18 months to 5 years2,00,000 IUOral
  • Total: 9 doses up to 5 years
  • Given as oily preparation of retinol palmitate

Indications for therapeutic supplementation:

  • Severe acute malnutrition
  • Measles
  • Persistent diarrhoea (>14 days)
  • Night blindness, Bitot's spots, xerophthalmia

Dietary sources: Liver, egg yolk, dairy, yellow/orange vegetables (beta-carotene), dark green leafy vegetables


Q15. Health Problems of the Elderly (2-3 Marks)

With India's aging population (>60 years = ~10% of population), elderly health is a growing concern.

Common Health Problems:

Physical:
  • Cardiovascular diseases (hypertension, IHD, heart failure)
  • Diabetes mellitus (Type 2)
  • Arthritis and musculoskeletal problems (osteoarthritis, osteoporosis)
  • Cancers (higher incidence with age)
  • Respiratory diseases (COPD)
  • Sensory impairments: Presbyopia, cataracts, presbycusis (hearing loss)
  • Dental problems: Tooth loss, xerostomia
  • Urinary incontinence, BPH in males
  • Falls and fractures (hip fracture = major cause of disability)
Mental:
  • Dementia (Alzheimer's disease most common)
  • Depression and anxiety
  • Delirium
Social:
  • Social isolation, loneliness
  • Neglect and elder abuse
  • Financial dependency
  • Polypharmacy (multiple medications)
National Programme for Health Care of Elderly (NPHCE): Launched 2010-11; provides dedicated wards, rehabilitation services, and geriatric OPD.

Q16. Child Abuse (2-3 Marks)

Child abuse is any act or failure to act that results in harm, potential for harm, or threat of harm to a child under 18 years.

Types:

  1. Physical abuse - hitting, burning, shaking, biting
  2. Sexual abuse - any sexual activity involving a child (POCSO Act 2012 in India)
  3. Emotional/Psychological abuse - verbal abuse, humiliation, rejection, threats
  4. Neglect - failure to provide basic needs (food, shelter, education, medical care)
  5. Child labour - economic exploitation

Indicators of Physical Abuse:

  • Bruises in unusual locations (back, buttocks, face)
  • Burns in specific patterns (cigarette burns, immersion burns)
  • Fractures inconsistent with developmental stage
  • Retinal haemorrhage (shaken baby syndrome)
  • Delay in seeking medical care

Management (4 R's):

  • Recognize - identify signs of abuse
  • Report - mandatory reporting (Childline 1098 in India)
  • Respond - immediate medical care and safety
  • Refer - to social services, child protection units

Q17. Baby Friendly Hospital Initiative (BFHI) (2-3 Marks)

BFHI is a global programme launched jointly by WHO and UNICEF in 1991 to promote, protect, and support breastfeeding.

The "Ten Steps to Successful Breastfeeding":

  1. Written breastfeeding policy communicated to all staff
  2. Train all health care staff in skills to implement the policy
  3. Inform all pregnant women about the benefits and management of breastfeeding
  4. Help mothers initiate breastfeeding within half an hour of birth (early initiation)
  5. Show mothers how to breastfeed and maintain lactation even if separated
  6. Give newborns no food or drink other than breast milk (no prelacteal feeds)
  7. Practice rooming-in (allow mothers and infants to remain together 24 hours a day)
  8. Encourage breastfeeding on demand
  9. Give no artificial teats, pacifiers, or dummies
  10. Foster establishment of breastfeeding support groups and refer mothers on discharge
In India: "Maa" (Mothers' Absolute Affection) programme (2016) promotes breastfeeding.

Q18. MDR (Multi-Drug Resistant Tuberculosis) (2-3 Marks)

MDR-TB is defined as tuberculosis caused by Mycobacterium tuberculosis resistant to at least both Isoniazid (H) and Rifampicin (R), the two most effective first-line anti-TB drugs.

Types of Drug Resistance:

  • Primary resistance: In a patient with no prior TB treatment
  • Acquired (secondary) resistance: Develops during or after inadequate treatment
  • XDR-TB (Extensively Drug Resistant): MDR-TB + resistance to any fluoroquinolone AND at least one of the second-line injectable drugs (amikacin, kanamycin, capreomycin)
  • TDR-TB (Totally Drug Resistant): Resistant to all first and second-line drugs

Causes of MDR-TB:

  1. Irregular/incomplete treatment
  2. Inadequate drug regimens
  3. Poor quality drugs
  4. Malabsorption
  5. Transmission from MDR-TB cases

Treatment (under PMDT - Programmatic Management of Drug Resistant TB in India):

  • Bedaquiline-based shorter oral regimen (6-9 months) - now preferred
  • Older longer regimens: 18-24 months
  • Managed through NIKSHAY portal in India

India's Burden: India has the highest MDR-TB burden globally (~26% of global cases).


Q19. Define Epidemic and Endemic (2-3 Marks)

Endemic:

The constant presence of a disease or infectious agent within a given geographic area or population group, without importation from outside. The disease occurs at the expected (baseline) level.
  • Example: Malaria in sub-Saharan Africa; Kala-azar (visceral leishmaniasis) in Bihar/Jharkhand

Epidemic:

The occurrence of cases of illness (or events) clearly in excess of normal expectancy in a community or region. An epidemic implies a rate of occurrence that is significantly higher than the expected (endemic) level.
  • Example: COVID-19 epidemic in 2020, cholera outbreak

Related Terms:

  • Pandemic: An epidemic that has spread over several countries/continents, usually affecting a large number of people (e.g., COVID-19 pandemic, Influenza 1918)
  • Outbreak: Similar to epidemic but often more localized, or used when the number of cases is small (e.g., food poisoning outbreak at a party)
  • Sporadic: Occasional cases occurring irregularly, with no particular pattern
  • Cluster: Aggregation of cases in a specific time and place

Q20. Principles of Chlorination (2-3 Marks)

Chlorination is the most widely used method of water disinfection. It involves addition of chlorine to water to destroy pathogenic microorganisms.

Principles:

1. Mechanism of Action:
  • Chlorine reacts with water to form hypochlorous acid (HOCl) and hypochlorite ion (OCl-)
  • HOCl is the active disinfecting agent (more germicidal than OCl-)
  • Destroys cell membranes and inactivates enzymes of microorganisms
  • Effective against bacteria, viruses, and some protozoa (not Cryptosporidium)
2. Residual Chlorine Concept:
  • Free residual chlorine = 0.2 mg/L (ppm) at the consumer's tap after 30 minutes contact time at pH 7 (Horrock's apparatus used for field testing)
  • Ensures continued disinfection during distribution
3. Chlorine Demand:
  • Amount of chlorine consumed by organic matter, bacteria, and other reducing agents before residual chlorine remains
  • Chlorine demand = Total chlorine added - Residual chlorine
4. Break-point Chlorination:
  • Sufficient chlorine is added to oxidize all organic matter and ammonia, after which residual chlorine appears. The point at which this occurs is the break-point. Adding chlorine beyond this gives free residual chlorine.
5. Factors Affecting Efficacy:
  • pH (lower pH = more HOCl = better germicidal action; optimal pH 6-7)
  • Temperature (higher temperature = faster action)
  • Contact time (minimum 30 minutes)
  • Turbidity (organic matter consumes chlorine; hence pre-treatment/sedimentation needed)
6. Superchlorination and Dechlorination:
  • Adding very high dose (1-2 ppm) followed by removal of excess chlorine by sodium thiosulphate
Forms of chlorine used:
  • Chlorine gas, bleaching powder (contains 30-35% available chlorine), chloramines, sodium hypochlorite, high-test hypochlorite (HTH - 60-70% available chlorine)

All answers are based on Park's Textbook of Preventive and Social Medicine (25th edition) and standard PSM curriculum.
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