Topics :

Topics :

Topics : Pleomorphic Adenoma , adenolymphoma , papillary thyroid carcinoma , fibroadenoma , phyllodes tumour , mondors disease , gynaecomastia , GERD , stomas , large bowel obstruction, minimally invasive surgery .Exam oriented detailing - ETIOLOGY , PATHOGENESIS, CLINICAL FEATURES , TREATMENT AND COMPLICATIONS

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general-purpose

You are a medical research agent. Search the medical textbook library database for detailed exam-oriented information on the following surgical/pathology topics. For each topic, retrieve information on: ETIOLOGY, PATHOGENESIS, CLINICAL FEATURES, TREATMENT, and COMPLICATIONS. TOPICS TO RESEARCH: 1. Pleomorphic Adenoma (mixed parotid tumor) 2. Adenolymphoma / Warthin's tumor (parotid gland) 3. Papillary Thyroid Carcinoma 4. Fibroadenoma (breast) 5. Phyllodes Tumour (breast) 6. Mondor's Disease (breast/chest) For each topic, use the medical library skill as follows: First read the skill: read_file('/skills/readonly/medical-library/SKILL.md') Then search using parallel queries like: - query_library_db with headings_fts for each topic - query_library_db with paragraphs_fts for specific details Example SQL for headings search: SELECT title, book_title, '/textbooks/' || block_file_path AS file_path, line_number, para_line_ranges, para_count FROM headings_fts WHERE headings_fts MATCH 'pleomorphic adenoma' ORDER BY rank LIMIT 5 Example SQL for paragraph search: SELECT book_title, section_heading, '/textbooks/' || block_file_path AS file_path, line_start, line_end, snippet(paragraphs_fts, 0, '>>>', '<<<', '...', 40) as snippet FROM paragraphs_fts WHERE paragraphs_fts MATCH 'pleomorphic adenoma' ORDER BY rank LIMIT 8 After finding file paths and line numbers, use read_file to read the actual content. Read ~100 lines around each relevant heading. IMPORTANT: Return a comprehensive structured summary for each of the 6 topics with all five categories (Etiology, Pathogenesis, Clinical Features, Treatment, Complications). Include specific exam facts like percentages, eponyms, classifications, staging, and mnemonics where found. Be thorough and detailed.

general-purpose

You are a medical research agent. Search the medical textbook library database for detailed exam-oriented information on the following surgical topics. For each topic, retrieve information on: ETIOLOGY, PATHOGENESIS, CLINICAL FEATURES, TREATMENT, and COMPLICATIONS. TOPICS TO RESEARCH: 1. Gynaecomastia 2. GERD (Gastroesophageal Reflux Disease) 3. Stomas (colostomy, ileostomy, types and complications) 4. Large Bowel Obstruction 5. Minimally Invasive Surgery (laparoscopy - principles, advantages, complications) For each topic, use the medical library skill as follows: First read the skill: read_file('/skills/readonly/medical-library/SKILL.md') Then search using parallel queries like headings_fts and paragraphs_fts: Example SQL for headings search: SELECT title, book_title, '/textbooks/' || block_file_path AS file_path, line_number, para_line_ranges, para_count FROM headings_fts WHERE headings_fts MATCH 'gynaecomastia' ORDER BY rank LIMIT 5 Example SQL for paragraph search: SELECT book_title, section_heading, '/textbooks/' || block_file_path AS file_path, line_start, line_end, snippet(paragraphs_fts, 0, '>>>', '<<<', '...', 40) as snippet FROM paragraphs_fts WHERE paragraphs_fts MATCH 'GERD gastroesophageal reflux' ORDER BY rank LIMIT 8 After finding file paths and line numbers, use read_file to read the actual content. Read ~100 lines around each relevant heading. IMPORTANT: Return a comprehensive structured summary for each of the 5 topics with all five categories (Etiology, Pathogenesis, Clinical Features, Treatment, Complications). Include specific exam facts like percentages, eponyms, classifications, staging, and mnemonics where found. Be thorough and detailed - this is for surgical exam preparation.

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All 11 topics are covered. Here's a quick orientation to the notes above:

How to Use These Notes

Salivary Gland Tumors (Topics 1 & 2):
  • Pleomorphic Adenoma: Remember no enucleation (pseudopods → recurrence), PLAG1 mutation, and the 10% malignant transformation at >15 years
  • Warthin's: Smoking 8×, bilateral 10%, hot on Tc-99m, oncocytic epithelium + lymphoid stroma — pathognomonic histology
Thyroid (Topic 3):
  • PTC = most common thyroid cancer; BRAF V600E = most common mutation; Orphan Annie nuclei + psammoma bodies = classic histology; excellent prognosis (>95% 10-yr survival)
Breast (Topics 4–6):
  • Fibroadenoma → observe if classic; MED12 mutation; NOT premalignant
  • Phyllodes → wider margins needed; NO axillary dissection; mets = sarcoma pattern
  • Mondor's → tender cord + skin dimpling → NSAIDs; self-limiting 4–6 weeks
Gynaecomastia (Topic 7):
  • Core = estrogen:androgen imbalance; Tamoxifen for active phase; Klinefelter = highest male breast cancer risk
GERD (Topic 8):
  • TLESRs = primary mechanism; Barrett's pathway → RFA/EMR for HGD; Nissen fundoplication for surgery
Stomas (Topic 9):
  • Brooke ileostomy = spouted; Parastomal hernia = most common late complication; IPAA = 8–10 BM/day
Large Bowel Obstruction (Topic 10):
  • CRC 60%; Competent ICV → closed loop → caecum perforates; Coffee bean sign = sigmoid volvulus; Hartmann's = standard emergency op
Minimally Invasive Surgery (Topic 11):
  • 12 mmHg CO₂; Gas embolism → Durant maneuver (left lateral decubitus + head-down); Urine output unreliable intraoperatively
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