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General/Systematic Patient Assessment

A complete patient assessment is the foundation of clinical medicine. Even in the modern era of advanced diagnostics, history and physical examination contribute at least 75% of the information that informs diagnosis - Goldman-Cecil Medicine notes that symptoms unexplained by initial comprehensive evaluation rarely represent serious disease.

1. Chief Complaint (CC)

The opening statement, in the patient's own words, that prompted them to seek care. It sets the focus for the entire encounter. Record it briefly and directly (e.g., "chest pain for 2 hours").

2. History of Present Illness (HPI)

Systematically characterize every symptom using the OLD CARTS or SOCRATES framework:
ElementWhat to Elicit
OnsetWhen did it start? Gradual or abrupt?
LocationWhere exactly? Does it radiate?
DurationHow long does each episode last?
CharacterSharp, dull, burning, crampy, colicky?
Aggravating/AlleviatingWhat makes it worse or better? (food, position, activity)
RadiationDoes it spread anywhere?
TimingConstant vs. intermittent? Pattern?
Severity0-10 scale; how does it affect daily function?
Per Goldman-Cecil Medicine, also elicit:
  • Acuity (steady vs. colicky; abrupt vs. gradual)
  • Relationship to meals, bowel movements, activity
  • Recent dietary intake, medication history, travel, and infection exposures
  • Systemic symptoms: fever, weight loss, fatigue, night sweats, arthralgias, rash

3. Past Medical History (PMH)

  • Known chronic illnesses (diabetes, hypertension, heart disease, thyroid disease, renal/hepatic disease, HIV)
  • Prior hospitalizations and surgeries
  • Previous similar episodes
  • Immunosuppression (iatrogenic, infectious, or inherited)
  • Obstetric/gynecologic history (pregnancies, LMP)
  • Psychiatric history

4. Medication History

  • All prescription medications (name, dose, frequency, duration)
  • Over-the-counter drugs, vitamins, dietary supplements, herbal remedies
  • Recent changes or new starts
  • Allergies: medications, foods, environmental antigens, and contactants - document reaction type (rash vs. anaphylaxis)

5. Family History (FH)

  • First-degree relatives' major diseases (cancer, heart disease, diabetes, genetic disorders, atopy)
  • Age at diagnosis and cause of death in parents/siblings

6. Social History (SH)

Per Fitzpatrick's Dermatology and Goldman-Cecil:
  • Occupation and workplace exposures
  • Hobbies and leisure activities
  • Tobacco use (pack-years), alcohol (units/week), illicit drug use
  • Sexual history (partners, practices, STI risk factors)
  • Living situation (alone, family, housing stability)
  • Diet and exercise habits
  • Travel history (endemic disease areas)
  • Cultural or religious practices that may affect care

7. Review of Systems (ROS)

A systematic organ-by-organ screen to catch symptoms the patient may not have volunteered. May be focused (guided by the CC) or comprehensive:
SystemKey Symptoms to Screen
ConstitutionalFever, chills, weight change, fatigue, night sweats
HEENTHeadache, vision changes, hearing loss, nasal discharge, sore throat
CardiovascularChest pain, palpitations, dyspnea, orthopnea, PND, edema, syncope
RespiratoryDyspnea, cough (productive/dry), hemoptysis, wheezing
GINausea, vomiting, dysphagia, abdominal pain, bowel habit changes, rectal bleeding, jaundice
GUDysuria, frequency, hematuria, discharge, sexual dysfunction
MSKJoint pain/swelling, stiffness, muscle weakness
NeuroHeadache, dizziness, weakness, paresthesias, seizures, changes in cognition
SkinRashes, lesions, pruritus, hair/nail changes
EndoPolyuria, polydipsia, heat/cold intolerance, menstrual irregularity
PsychDepression, anxiety, sleep disturbance, suicidal ideation
Heme/LymphEasy bruising, bleeding, lymphadenopathy

8. Physical Examination

General Impression

Observe before touching: Does the patient look well or ill? Comfortable or in distress? Obese, cachectic, or normal weight? Skin color (pallor, jaundice, cyanosis)? Skin temperature and turgor?

Vital Signs

ParameterNormal Adult Range
Temperature36.1 - 37.2 °C (97 - 99 °F)
Heart rate60-100 bpm
Respiratory rate12-20 breaths/min
Blood pressure<120/80 mmHg
O2 saturation≥95% (SpO2)
Pain score0-10 (NRS)
Weight, height, and BMI are part of a complete set.

Head-to-Toe Examination

Head/Face: Normocephalic, atraumatic; facial symmetry, temporal wasting.
Eyes (PERRL): Pupils equal, round, reactive to light; conjunctivae, sclerae (jaundice, anemia), fundoscopy when indicated.
Ears: Hearing, external canal, tympanic membranes.
Nose/Mouth/Throat: Mucous membranes (moisture = hydration status), dentition, tonsils, pharynx.
Neck: Lymphadenopathy, thyroid size and consistency, carotid bruits, JVD, tracheal position.
Chest/Respiratory: Chest wall shape, respiratory effort, percussion (dullness = fluid/consolidation; hyperresonance = pneumothorax), auscultation (air entry, crackles, wheeze, pleural rub).
Cardiovascular: Apex beat, heart sounds S1/S2, extra sounds (S3/S4, murmurs), peripheral pulses (rate, rhythm, volume), ankle-brachial index (ABI) for vascular assessment when PAD is suspected.
Abdomen: Inspection (scars, distension), auscultation (bowel sounds), percussion (liver/spleen size, ascites), palpation (tenderness, guarding, rebound, organomegaly). Assess relationship of symptoms to food/bowel movements.
Genitourinary/Rectal: Indicated by clinical context.
Musculoskeletal: Range of motion, joint swelling/tenderness, deformities, muscle strength (MRC grading 0-5), gait.
Neurological: Mental status (GCS or orientation x3), cranial nerves, motor/sensory testing, reflexes (DTRs), coordination (finger-nose, heel-shin), cerebellar signs.
Skin: Describe lesions by morphology (primary vs. secondary), color, distribution, and configuration. Per Fitzpatrick's Dermatology, describe whether lesions are localized, grouped, regional, symmetrical, sun-exposed, flexural, or dermatomal.

9. Functional Assessment

  • Ability to perform activities of daily living (ADLs) and instrumental ADLs
  • Metabolic equivalents (METs) - ≥4 METs (e.g., climbing a flight of stairs) indicates adequate functional capacity for perioperative risk stratification per ACC/AHA guidelines
  • Social support and home environment

10. Problem List and Impression

After gathering the above data:
  1. List all active problems
  2. Formulate a differential diagnosis for each problem (ranked by probability)
  3. Outline the diagnostic plan (labs, imaging, procedures)
  4. Develop a management plan

Key Principle

As Goldman-Cecil Medicine emphasizes: "The fundamental basis of internal medicine is that diagnosis should elucidate the pathophysiologic explanation for symptoms and signs so that therapy may improve the underlying abnormality, not just attempt to suppress the abnormal symptoms or signs." History and physical examination remain the most powerful diagnostic tools available - they provide the context within which all test results must be interpreted.
Sources consulted:
  • Goldman-Cecil Medicine International Edition (2 Vol Set)
  • Fitzpatrick's Dermatology, Volumes 1 & 2
  • Current Surgical Therapy, 14th Edition
  • Bailey and Love's Short Practice of Surgery, 28th Edition
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