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How much dosage of thyroxin tab can prescribe? Currently she is on 75mg once.

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"Hypothyroidism"[MeSH Terms] AND levothyroxine

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American Thyroid Association levothyroxine dose adjustment TSH 12.5 25 mcg 6 weeks hypothyroidism

The tablet should be 75 micrograms (mcg or µg), not 75 mg. A 75 mg dose would be dangerously incorrect.
From the report: age 46, TSH 5.067 mIU/L (slightly high; lab upper limit 4.2) with total T4 10.59 µg/dL (normal). This can mean mild under-replacement, but a dose change should depend on how long she has been consistently taking 75 mcg, symptoms, weight, cardiac history, pregnancy status, and ideally free T4.
Usual clinical approach, if she has taken 75 mcg correctly for at least 6-8 weeks and is not pregnant or cardiac-risk:
  • Check adherence and interactions first.
  • If adjustment is appropriate, clinicians generally increase by only 12.5-25 mcg/day.
  • Thus, common next doses are 88 mcg once daily or 100 mcg once daily, selected by her prescriber.
  • Recheck TSH, preferably with free T4, in 6-8 weeks. AAFP guidance supports 12.5-25 mcg increments for high TSH, with repeat testing after 6-8 weeks.
Do not increase on the basis of this one value if:
  • the test was done within 6-8 weeks of starting/changing dose,
  • doses are missed,
  • she takes it with food, tea/coffee, calcium, iron, antacids, or certain acid-reducing medicines,
  • she has angina, arrhythmia, or known coronary disease,
  • she is pregnant or planning pregnancy.
Take levothyroxine with water on an empty stomach, ideally 30-60 minutes before breakfast, and separate calcium/iron by at least 4 hours. If she gets palpitations, tremor, chest pain, marked anxiety, or insomnia after a change, seek medical review promptly.
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