const pptxgen = require("pptxgenjs");

let pres = new pptxgen();
// Use LAYOUT_WIDE for a poster-style card: 13.3" x 7.5"
pres.layout = 'LAYOUT_WIDE';

// ─── COLOR PALETTE ───────────────────────────────────────────────
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const PANEL     = "112240";   // Slightly lighter panel
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const ACCENT1   = "00B4D8";   // Cyan accent
const ACCENT2   = "F77F00";   // Orange accent
const ACCENT3   = "43AA8B";   // Teal green
const ACCENT4   = "E63946";   // Red accent
const ACCENT5   = "A8DADC";   // Light blue
const WHITE     = "FFFFFF";
const LGRAY     = "B0C4D8";
const YELLOW    = "FFD166";
const PURPLE    = "7B2D8B";
const LPURPLE   = "C77DFF";

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// ─── FULL BACKGROUND ─────────────────────────────────────────────
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// ─── HEADER BAND ─────────────────────────────────────────────────
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// TITLE
slide.addText("PROPTOSIS — COMPLETE CLINICAL REFERENCE", {
  x: 0.15, y: 0.05, w: 9.5, h: 0.45,
  fontSize: 18, bold: true, color: BG,
  fontFace: "Calibri", align: "left", valign: "middle", margin: 0
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slide.addText("Ophthalmology Resident Quick Reference  |  Kanski & Wills Eye Manual", {
  x: 9.7, y: 0.08, w: 3.4, h: 0.38,
  fontSize: 7.5, bold: false, color: BG,
  fontFace: "Calibri", align: "right", valign: "middle", margin: 0
});

// ─── LAYOUT: 4 columns below header ──────────────────────────────
// Col 1: x=0.1  w=3.1
// Col 2: x=3.3  w=3.1
// Col 3: x=6.5  w=3.1
// Col 4: x=9.7  w=3.5
const Y0 = 0.68;   // Top of content
const CH = 6.75;   // Content height

// ─── HELPER FUNCTIONS ────────────────────────────────────────────
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// ══════════════════════════════════════════════════════
// COLUMN 1: DEFINITION + CLASSIFICATION + PSEUDOPROPTOSIS
// ══════════════════════════════════════════════════════
let cx = 0.1;
panelBg(cx, Y0, 3.1, CH);

// --- DEFINITION ---
sectionHeader("📌  DEFINITION & BASICS", cx, Y0, 3.1, ACCENT1);
bodyText([
  { text: "Proptosis: Abnormal anterior displacement of the globe beyond the orbital rim", bold: false, color: WHITE },
  { text: "Exophthalmos: Term specifically for thyroid-related proptosis", color: LGRAY },
  { text: "Normal: ≤20 mm from lateral orbital rim to corneal apex (Hertel)", color: LGRAY },
  { text: "Abnormal: >20 mm or asymmetry ≥2–3 mm between eyes", bold: true, color: YELLOW },
  { text: "Measurement: Hertel exophthalmometer (Oculus)", color: LGRAY },
  { text: "  • Resting & Valsalva measurements", color: LGRAY },
  { text: "  • Axial proptosis → intraconal mass", color: ACCENT5 },
  { text: "  • Proptosis + dystopia → extraconal mass", color: ACCENT5 },
], cx + 0.06, Y0 + 0.28, 2.95, 0.9);

// --- CLASSIFICATION BY CAUSE ---
sectionHeader("🔷  ETIOLOGY CLASSIFICATION", cx, Y0 + 1.2, 3.1, ACCENT1);

// Six categories with color-coded mini-chips
const categories = [
  { label: "1. INFLAMMATORY", color: ACCENT3, items: [
    "Thyroid Eye Disease (TED) — MC cause in adults",
    "IOIS (Idiopathic Orbital Inflammatory Syndrome)",
    "Sarcoidosis",
    "GPA (Wegener's granulomatosis)",
    "IgG4-related orbital disease",
    "Reactive — paranasal sinusitis"
  ]},
  { label: "2. INFECTIOUS", color: ACCENT4, items: [
    "Orbital cellulitis",
    "Subperiosteal abscess (SPA)",
    "Mucormycosis (immunocompromised)",
    "Cavernous sinus thrombosis"
  ]},
  { label: "3. NEOPLASTIC", color: ACCENT2, items: [
    "PRIMARY: Cavernous hemangioma (MC benign adult), Optic nerve glioma, Meningioma, Dermoid cyst (MC in children), Solitary fibrous tumor, Lymphoma",
    "SECONDARY: Sinus extension, Intracranial meningioma, Lacrimal gland tumor",
    "METASTATIC: Breast, Lung, Prostate — assume mets if cancer Hx"
  ]},
  { label: "4. VASCULAR", color: LPURPLE, items: [
    "Carotid-cavernous fistula (CCF) — pulsatile proptosis",
    "Orbital varices — positional/intermittent",
    "Lymphangioma — hemorrhage → sudden onset",
    "Arteriovenous malformation"
  ]},
  { label: "5. TRAUMA", color: YELLOW, items: [
    "Retrobulbar hemorrhage — sight-threatening emergency",
    "Orbital fracture (blowout)",
    "Orbital foreign body",
  ]},
  { label: "6. CONGENITAL/STRUCTURAL", color: ACCENT5, items: [
    "Craniosynostosis (Crouzon, Apert)",
    "Neurofibromatosis (sphenoid wing dysplasia)",
    "Shallow orbit"
  ]}
];

let yPos = Y0 + 1.48;
categories.forEach(cat => {
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    x: cx + 0.06, y: yPos, w: 2.9, h: 0.17,
    fill: { color: cat.color, transparency: 20 },
    line: { color: cat.color }
  });
  slide.addText(cat.label, {
    x: cx + 0.08, y: yPos, w: 2.86, h: 0.17,
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  yPos += 0.18;
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    slide.addText("• " + item, {
      x: cx + 0.12, y: yPos, w: 2.82, h: 0.135,
      fontSize: 5.8, color: LGRAY, fontFace: "Calibri", valign: "top", margin: [1,2,1,2]
    });
    yPos += 0.138;
  });
  yPos += 0.03;
});

// --- PSEUDOPROPTOSIS ---
sectionHeader("⚠️  PSEUDOPROPTOSIS", cx, yPos + 0.02, 3.1, ACCENT3);
bodyText([
  { text: "• High myopia / Buphthalmos (large globe)", color: LGRAY },
  { text: "• Lid retraction (unilateral)", color: LGRAY },
  { text: "• Contralateral enophthalmos", color: LGRAY },
  { text: "• Facial asymmetry", color: LGRAY },
], cx + 0.06, yPos + 0.3, 2.95, 0.42);


// ══════════════════════════════════════════════════════
// COLUMN 2: CLINICAL EXAMINATION
// ══════════════════════════════════════════════════════
cx = 3.3;
panelBg(cx, Y0, 3.1, CH);

sectionHeader("🔬  CLINICAL EXAMINATION", cx, Y0, 3.1, ACCENT2);

// Systematic Exam steps
const examSteps = [
  { step: "1. HISTORY", color: ACCENT2, items: [
    "Onset: Acute (<48h) → infection/hemorrhage/trauma",
    "          Subacute (wks) → inflammation",
    "          Chronic (mos-yrs) → neoplasm",
    "Unilateral vs Bilateral",
    "Associated: pain, diplopia, vision loss, headache",
    "Systemic: thyroid Dx, cancer, DM, TB, sarcoid",
    "Positional change → venous/vascular"
  ]},
  { step: "2. INSPECT", color: ACCENT3, items: [
    "Direction of proptosis (axial vs eccentric)",
    "Eyelid: Retraction (TED — Dalrymple sign)",
    "         Lag on downgaze (von Graefe's sign)",
    "         Chemosis, injection, edema",
    "Pulsation → CCF, NF/sphenoid dysplasia",
    "S-shaped lid deformity → lacrimal gland tumor"
  ]},
  { step: "3. MEASURE", color: ACCENT1, items: [
    "Hertel exophthalmometer: base + reading",
    ">20 mm or ≥2–3 mm asymmetry = abnormal",
    "Palpebral aperture width",
    "Lagophthalmos (corneal exposure risk)"
  ]},
  { step: "4. PALPATE", color: YELLOW, items: [
    "Resistance to retropulsion (resistance → mass/edema)",
    "Palpate for mass: location, firmness, tenderness",
    "Auscultate for bruit → CCF/AVM",
    "Lacrimal gland palpation",
    "Regional lymph nodes"
  ]},
  { step: "5. OCULAR MOTILITY", color: LPURPLE, items: [
    "Restriction pattern:",
    "  TED: inferior rectus (↑gaze restricted) #1",
    "  Then medial, superior, lateral rectus",
    "Forced duction test (restrictive vs neurologic)",
    "Force generation test",
    "Cover test, prism assessment"
  ]},
  { step: "6. VISUAL FUNCTION", color: ACCENT4, items: [
    "Best corrected visual acuity",
    "Color vision (Ishihara/D15) — early ON compression",
    "Pupillary exam (RAPD)",
    "Visual fields (APD, cecocentral defect)",
    "Fundus: disc edema, optociliary vessels",
    "IOP in all positions of gaze"
  ]},
  { step: "7. SLIT LAMP", color: ACCENT5, items: [
    "Corneal exposure keratopathy",
    "Superior limbic keratoconjunctivitis (SLK)",
    "Conjunctival injection/chemosis",
    "Anterior segment: rubeosis?"
  ]}
];

let yp = Y0 + 0.28;
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    x: cx + 0.06, y: yp, w: 2.9, h: 0.16,
    fill: { color: step.color, transparency: 25 },
    line: { color: step.color }
  });
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    x: cx + 0.08, y: yp, w: 2.86, h: 0.16,
    fontSize: 5.8, bold: true, color: BG,
    fontFace: "Calibri", valign: "middle", margin: 0
  });
  yp += 0.17;
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    slide.addText("• " + item, {
      x: cx + 0.12, y: yp, w: 2.82, h: 0.13,
      fontSize: 5.6, color: LGRAY, fontFace: "Calibri", valign: "top", margin: [0.5,2,0.5,2]
    });
    yp += 0.125;
  });
  yp += 0.04;
});


// ══════════════════════════════════════════════════════
// COLUMN 3: INVESTIGATIONS + TED (MOST COMMON CAUSE)
// ══════════════════════════════════════════════════════
cx = 6.5;
panelBg(cx, Y0, 3.1, CH);

sectionHeader("🧪  INVESTIGATIONS", cx, Y0, 3.1, ACCENT3);

const invRows = [
  { hdr: "BLOODS", color: ACCENT3, items: [
    "FBC, ESR, CRP (infection/inflammation)",
    "TFTs: TSH, free T4, T3",
    "TSH-receptor Ab (TRAb) — TED specific",
    "ANCA (GPA), ACE (sarcoid), IgG4",
    "FBS, HbA1c (mucor risk)",
    "Tumour markers if metastasis suspected"
  ]},
  { hdr: "IMAGING", color: ACCENT1, items: [
    "CT Orbit (HRCT) — FIRST LINE",
    "  → Bone erosion, bony lesions, sinuses",
    "  → Muscle enlargement pattern (TED)",
    "MRI Orbit — SOFT TISSUE detail",
    "  → Optic nerve, cavernous sinus, intracranial ext.",
    "  → Fat suppressed T1+Gd for infiltrative",
    "Doppler US — vascular lesions, CCF",
    "B-scan US — optic nerve sheath diam, mass",
    "CXR/CT Chest — sarcoid/lymphoma/mets"
  ]},
  { hdr: "ORBITAL US (B-SCAN)", color: ACCENT2, items: [
    "Cavernous hemangioma → high internal reflectivity",
    "Lymphangioma → irregular, no vascularity",
    "ON sheath >5mm → increased ICP"
  ]},
  { hdr: "HISTOPATHOLOGY", color: ACCENT4, items: [
    "Incisional / excisional biopsy",
    "Fine needle aspiration cytology (FNAC)",
    "  → Lymphoma, metastasis, lacrimal mass"
  ]},
  { hdr: "SPECIAL TESTS", color: YELLOW, items: [
    "CAS score (TED activity — 7 items)",
    "Hertel baseline + serial measurements",
    "Humphrey visual field",
    "VEP (optic nerve compression)",
    "IOP (↑ in upgaze >6 mmHg → TED)"
  ]}
];

let ypi = Y0 + 0.28;
invRows.forEach(row => {
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    x: cx + 0.06, y: ypi, w: 2.9, h: 0.16,
    fill: { color: row.color, transparency: 20 },
    line: { color: row.color }
  });
  slide.addText(row.hdr, {
    x: cx + 0.08, y: ypi, w: 2.86, h: 0.16,
    fontSize: 6.0, bold: true, color: BG,
    fontFace: "Calibri", valign: "middle", margin: 0
  });
  ypi += 0.17;
  row.items.forEach(item => {
    slide.addText("• " + item, {
      x: cx + 0.12, y: ypi, w: 2.82, h: 0.128,
      fontSize: 5.6, color: LGRAY, fontFace: "Calibri", valign: "top", margin: [0.5,2,0.5,2]
    });
    ypi += 0.126;
  });
  ypi += 0.04;
});

// TED section below if space
sectionHeader("🦋  TED (MC CAUSE) — CAS SCORE", cx, ypi + 0.02, 3.1, ACCENT2);
ypi += 0.22;
const casItems = [
  "1. Spontaneous retrobulbar pain",
  "2. Pain on upward/downward gaze",
  "3. Redness of eyelids",
  "4. Diffuse redness of conjunctiva",
  "5. Swelling of conjunctiva (chemosis)/plica",
  "6. Swelling of eyelid(s)",
  "7. Proptosis ≥2mm in 1–3 months",
  "CAS ≥3/7 = Active disease → immunosuppression",
];
casItems.forEach(item => {
  const isBold = item.startsWith("CAS");
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    x: cx + 0.12, y: ypi, w: 2.82, h: 0.128,
    fontSize: 5.7, color: isBold ? YELLOW : LGRAY, bold: isBold,
    fontFace: "Calibri", valign: "top", margin: [0.5,2,0.5,2]
  });
  ypi += 0.126;
});


// ══════════════════════════════════════════════════════
// COLUMN 4: MANAGEMENT + KEY EMERGENCIES
// ══════════════════════════════════════════════════════
cx = 9.7;
panelBg(cx, Y0, 3.5, CH);

sectionHeader("💊  MANAGEMENT OVERVIEW", cx, Y0, 3.5, ACCENT4);

const mgmt = [
  { hdr: "TED — MILD", color: ACCENT3, items: [
    "Stop smoking (↓ severity 3×)",
    "Treat thyroid (euthyroid state)",
    "Selenium 200μg/day × 6 months",
    "Lubricants, prism glasses for diplopia",
    "Sunglasses for photophobia"
  ]},
  { hdr: "TED — MODERATE-SEVERE (Active, CAS≥3)", color: ACCENT2, items: [
    "IV methylprednisolone (EUGOGO protocol)",
    "  500mg/wk × 6 wks → 250mg/wk × 6 wks",
    "Teprotumumab (IGF-1R inhibitor) — 1st line USA",
    "Orbital radiotherapy (10-20 Gy, fractionated)",
    "Rituximab (anti-CD20) if steroid-refractory"
  ]},
  { hdr: "TED — SURGICAL (Inactive, stable ≥6 months)", color: YELLOW, items: [
    "SEQUENCE: Decompression → Strabismus → Lids",
    "1. Orbital decompression (proptosis >3mm mod-sev)",
    "   → Balanced (medial+lateral), 3-wall (severe)",
    "2. Strabismus surgery (restrictive diplopia)",
    "3. Eyelid: Recession for retraction / tarsorrhaphy"
  ]},
  { hdr: "ORBITAL CELLULITIS (Chandler Grade)", color: ACCENT4, items: [
    "I: Preseptal — oral amoxiclav, observe 24h",
    "II: Orbital — IV antibiotics (co-amoxiclav + metro)",
    "III: Subperiosteal abscess",
    "IV: Orbital abscess → surgical drainage",
    "V: Cavernous sinus thrombosis → IV + anticoag",
    "Causative: S. aureus, Strep, H. influenzae (children)"
  ]},
  { hdr: "NEOPLASTIC — BENIGN", color: ACCENT5, items: [
    "Cavernous hemangioma → observation or excision",
    "Dermoid cyst → complete excision (prevent rupture)",
    "Optic nerve glioma → observe (NF1), RT/chemo",
    "Meningioma → observe, RT, or surgery"
  ]},
  { hdr: "NEOPLASTIC — MALIGNANT", color: ACCENT4, items: [
    "Lymphoma → orbital RT ± systemic chemo/rituximab",
    "Metastasis → identify primary; palliative RT",
    "RMS (children) → chemo+RT, avoid exenteration",
    "Lacrimal gland AdCA → en bloc excision + RT"
  ]},
];

let ypm = Y0 + 0.28;
mgmt.forEach(sec => {
  slide.addShape(pres.shapes.RECTANGLE, {
    x: cx + 0.06, y: ypm, w: 3.34, h: 0.16,
    fill: { color: sec.color, transparency: 20 },
    line: { color: sec.color }
  });
  slide.addText(sec.hdr, {
    x: cx + 0.08, y: ypm, w: 3.3, h: 0.16,
    fontSize: 5.8, bold: true, color: BG,
    fontFace: "Calibri", valign: "middle", margin: 0
  });
  ypm += 0.17;
  sec.items.forEach(item => {
    slide.addText("• " + item, {
      x: cx + 0.12, y: ypm, w: 3.28, h: 0.13,
      fontSize: 5.7, color: LGRAY, fontFace: "Calibri", valign: "top", margin: [0.5,2,0.5,2]
    });
    ypm += 0.128;
  });
  ypm += 0.04;
});

// --- EMERGENCIES BOX ---
sectionHeader("🚨  SIGHT-THREATENING EMERGENCIES", cx, ypm + 0.02, 3.5, ACCENT4);
ypm += 0.22;
const emergencies = [
  { cond: "Retrobulbar hemorrhage", rx: "→ Lateral canthotomy + cantholysis STAT", color: ACCENT4 },
  { cond: "Orbital cellulitis w/ vision loss", rx: "→ Emergency surgical drainage", color: ACCENT4 },
  { cond: "TED optic neuropathy", rx: "→ IV MP 1g/day × 3d, urgent decompression", color: ACCENT2 },
  { cond: "Mucormycosis", rx: "→ IV liposomal AmB + surgical debridement", color: ACCENT4 },
  { cond: "Corneal exposure → perforation", rx: "→ Urgent tarsorrhaphy / decompression", color: YELLOW },
];
emergencies.forEach(e => {
  slide.addText([
    { text: e.cond + " ", options: { bold: true, color: e.color, fontSize: 5.8 } },
    { text: e.rx, options: { bold: false, color: LGRAY, fontSize: 5.6 } }
  ], {
    x: cx + 0.1, y: ypm, w: 3.3, h: 0.13,
    fontFace: "Calibri", valign: "top", margin: [1,2,1,2]
  });
  ypm += 0.132;
});

// --- QUICK REFERENCE CHART: Direction of Proptosis ---
ypm += 0.08;
sectionHeader("📐  DIRECTION → LIKELY LESION", cx, ypm, 3.5, ACCENT1);
ypm += 0.18;
const dirChart = [
  ["AXIAL (straight forward)", "Intraconal: Cavernous hemangioma, ON tumour"],
  ["DOWN & OUT", "Supermedial: Mucocele, frontal sinus"],
  ["UP (hyperglobus)", "Inferior: Maxillary sinus CA, floor mass"],
  ["DOWN (hypoglobus)", "Superior: Dermoid, lacrimal, meningioma"],
  ["PULSATILE", "CCF, NF (sphenoid dysplasia)"],
  ["INTERMITTENT", "Orbital varices (increases w/ Valsalva)"],
];
dirChart.forEach(row => {
  slide.addText([
    { text: row[0] + ": ", options: { bold: true, color: ACCENT5, fontSize: 5.5 } },
    { text: row[1], options: { color: LGRAY, fontSize: 5.5 } }
  ], {
    x: cx + 0.1, y: ypm, w: 3.3, h: 0.125,
    fontFace: "Calibri", valign: "top", margin: [0.5,2,0.5,2]
  });
  ypm += 0.126;
});

// ─── FOOTER ───────────────────────────────────────────
slide.addShape(pres.shapes.RECTANGLE, {
  x: 0, y: 7.38, w: 13.3, h: 0.12,
  fill: { color: ACCENT1 }, line: { color: ACCENT1 }
});
slide.addText("Sources: Kanski's Clinical Ophthalmology 10e | Wills Eye Manual 8e | EUGOGO Guidelines 2021  —  For Educational Use Only", {
  x: 0.2, y: 7.38, w: 12.9, h: 0.12,
  fontSize: 5.0, color: BG, fontFace: "Calibri",
  align: "center", valign: "middle", margin: 0
});

// ─── WRITE FILE ───────────────────────────────────────
pres.writeFile({ fileName: "/home/daytona/workspace/proptosis-poster/Proptosis_Clinical_Poster.pptx" })
  .then(() => console.log("SUCCESS: Poster saved."))
  .catch(e => console.error("ERROR:", e));