50 kg: 350 mg = 35 mL of 1% lidocaine with epinephrine
60 kg: 420 mg = 42 mL
70 kg: calculated 490 mg = 49 mL
≥72 kg: maximum 50 mL
For larger-field infiltration, dilute 1% lidocaine with epinephrine using normal saline while keeping the total lidocaine amount within the calculated limit. A commonly used dilution is 0.5% lidocaine with epinephrine, which allows twice the volume but not twice the lidocaine dose.
Allow approximately 25-30 minutes after injection for maximal epinephrine vasoconstriction before incision. Be prepared to treat local-anesthetic systemic toxicity and have phentolamine available for rare persistent epinephrine-related digital ischemia. Use added caution or avoid WALANT in severely compromised digital circulation, such as significant peripheral vascular disease or vasospastic disorders.
Source: Campbell's Operative Orthopaedics, 15th ed., WALANT section; the WALANT state-of-the-art review also describes the commonly recommended 7 mg/kg limit.
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