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This is a SpermoLyzer Computer Assisted Semen Analysis (CASA) report for Faizan Asad, age 26, dated 23/05/2026. The lab comment says "Normal seminal profile" and all key parameters passed WHO 2010 criteria - but there are notable sub-findings worth flagging. Here is a full analysis:
Semen Analysis Report - Abnormalities & Notable Findings
Patient: Faizan Asad | Age: 26 | Date: 23/05/2026
Physical Properties - Abnormalities
| Parameter | Result | Reference | Finding |
|---|---|---|---|
| Viscosity | Thick | Normal/Liquefied | ABNORMAL - increased viscosity |
| White Blood Cells | 2-3 /HPF | < 5 /HPF | Borderline - approaching leukocytospermia threshold |
Thick viscosity can interfere with sperm motility and forward progression, and may indicate accessory gland dysfunction (prostate or seminal vesicles). The lab noted "Complete" liquefaction, so the sample did liquefy at 30 minutes, but the viscosity remained thick.
Morphology - Significant Abnormalities (Page 4)
52.94% of sperm are teratozoospermic (abnormal forms). Specific defects found:
Head Abnormalities (most significant):
| Defect | Percentage |
|---|---|
| Big head | 17.65% |
| Amorphous head | 12% |
| No acrosome | 12% |
| Small head | 6% |
| Small acrosome | 6% |
- Big head (17.65%) - Macrocephalic sperm; often associated with polyploidy and genetic abnormalities
- Amorphous head (12%) - Irregularly shaped heads with no defined form
- No acrosome (12%) - Globozoospermia-type defect; acrosome is essential for fertilization (zona pellucida penetration). This is functionally significant - sperm without acrosomes cannot fertilize an egg naturally
Neck & Midpiece Abnormalities:
| Defect | Percentage |
|---|---|
| Bent neck | 12% |
Morphometric Comparison (Terato vs Normal sperms):
| Parameter | Normal | Terato | Reference |
|---|---|---|---|
| Head length | 4.36 µm | 4.71 µm | 4-5.5 µm |
| Head width | 3.01 µm | 3.12 µm | 2.5-3.5 µm |
| L/W ratio | 1.42 | 1.00 | 1.5-1.75 |
| Acrosome % | 50.61% | 34% | 40-70% |
The teratozoospermic sperm have a length/width ratio of 1.00 (below 1.5 reference) indicating abnormally round heads, and an acrosome percentage of 34% which is below the 40% lower reference limit.
Motility - Detailed Assessment (Page 2)
All motility parameters officially passed WHO thresholds, but kinematic parameters show low velocities:
| Parameter | Result | Finding |
|---|---|---|
| VCL (Curvilinear velocity) | 27.96 µm/s | Low (normal >25 µm/s, borderline) |
| VSL (Straight-line velocity) | 11.54 µm/s | Low (typically >16 µm/s preferred) |
| VAP (Average path velocity) | 17.68 µm/s | Low-normal |
| LIN (Linearity) | 46.78% | Borderline low |
| STR (Straightness) | 70.56% | Acceptable but low-normal |
The velocity histograms (Page 3) show that >62% of sperm have progressive velocity < 10 µm/s and >38% have track speed < 10 µm/s, confirming slow-moving progressive sperm despite meeting the basic WHO motility percentage cutoff.
26.04% immotile sperm - while within acceptable range (<40%), still a quarter of all sperm are non-functional.
Key Indices
| Index | Value | Significance |
|---|---|---|
| TZI (Teratozoospermic Index) | 1.11 | Mean defects per abnormal sperm (closer to 1 = better; acceptable) |
| MAI (Multiple Anomalies Index) | 1.22 | Mean anomalies per abnormal spermatozoon |
| SDI (Sperm Deformity Index) | 0.65 | Total defects / total sperm counted (>1.6 predicts IVF failure) |
Summary of Abnormalities
Despite the lab's overall "Normal seminal profile" comment (based on WHO count/motility/morphology index thresholds being met):
- Thick viscosity - physical abnormality, may impair sperm function
- 52.94% teratozoospermia - although morphology index of 47.06% passes the WHO ≥4% threshold, more than half the sperm are abnormally formed
- Big head sperm (17.65%) - associated with chromosomal/DNA abnormalities
- Acrosome-deficient sperm (12% no acrosome + 6% small acrosome = 18%) - major functional defect; these sperm cannot penetrate the zona pellucida
- Amorphous heads (12%) and Bent neck (12%) - structural defects
- Low sperm velocities (VCL, VSL, VAP all low-normal) indicating sluggish forward progression
- WBC 2-3/HPF - borderline; worth monitoring for subclinical genital tract infection
The "Passed" stamps reflect WHO minimum thresholds, not optimal fertility parameters. The acrosome deficiency in particular deserves attention if this patient is being evaluated for subfertility, as it may indicate the need for ICSI (intracytoplasmic sperm injection) rather than standard IUI or natural conception.
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