from reportlab.lib.pagesizes import A4
from reportlab.lib import colors
from reportlab.lib.styles import getSampleStyleSheet, ParagraphStyle
from reportlab.lib.units import cm
from reportlab.platypus import (
    SimpleDocTemplate, Paragraph, Spacer, Table, TableStyle,
    HRFlowable, PageBreak, ListFlowable, ListItem
)
from reportlab.lib.enums import TA_CENTER, TA_LEFT, TA_JUSTIFY
from reportlab.platypus import KeepTogether

OUTPUT = "/home/daytona/workspace/pharmacy-study-guide/Role_of_Pharmacist_Study_Guide.pdf"

# ── Colours ──────────────────────────────────────────────────────────────────
DARK_BLUE   = colors.HexColor("#1A3A5C")
MED_BLUE    = colors.HexColor("#2563A8")
LIGHT_BLUE  = colors.HexColor("#E8F0FB")
ACCENT      = colors.HexColor("#F4A81D")
WHITE       = colors.white
LIGHT_GRAY  = colors.HexColor("#F5F5F5")
MID_GRAY    = colors.HexColor("#D0D0D0")
TEXT_DARK   = colors.HexColor("#1C1C1C")
GREEN       = colors.HexColor("#1E7A44")
LIGHT_GREEN = colors.HexColor("#E6F4EC")
RED         = colors.HexColor("#C0392B")
LIGHT_RED   = colors.HexColor("#FDECEA")

doc = SimpleDocTemplate(
    OUTPUT,
    pagesize=A4,
    rightMargin=1.8*cm, leftMargin=1.8*cm,
    topMargin=2*cm,     bottomMargin=2*cm,
)

styles = getSampleStyleSheet()

# Custom styles
def S(name, **kw):
    return ParagraphStyle(name, **kw)

title_style = S("Title",
    fontSize=22, fontName="Helvetica-Bold",
    textColor=WHITE, alignment=TA_CENTER, spaceAfter=4)

subtitle_style = S("Subtitle",
    fontSize=11, fontName="Helvetica",
    textColor=LIGHT_BLUE, alignment=TA_CENTER, spaceAfter=2)

h1 = S("H1",
    fontSize=14, fontName="Helvetica-Bold",
    textColor=WHITE, spaceAfter=6, spaceBefore=4,
    leftIndent=0)

h2 = S("H2",
    fontSize=11, fontName="Helvetica-Bold",
    textColor=DARK_BLUE, spaceAfter=4, spaceBefore=8)

h3 = S("H3",
    fontSize=10, fontName="Helvetica-Bold",
    textColor=MED_BLUE, spaceAfter=3, spaceBefore=5)

body = S("Body",
    fontSize=9.5, fontName="Helvetica",
    textColor=TEXT_DARK, leading=14, spaceAfter=3,
    alignment=TA_JUSTIFY)

bullet_style = S("Bullet",
    fontSize=9.5, fontName="Helvetica",
    textColor=TEXT_DARK, leading=13,
    leftIndent=16, spaceAfter=2)

note_style = S("Note",
    fontSize=9, fontName="Helvetica-Oblique",
    textColor=GREEN, leading=13, leftIndent=8)

exam_style = S("Exam",
    fontSize=9.5, fontName="Helvetica-Bold",
    textColor=RED)

mcq_q = S("MCQ_Q",
    fontSize=9.5, fontName="Helvetica-Bold",
    textColor=TEXT_DARK, leading=13, spaceAfter=2)

mcq_a = S("MCQ_A",
    fontSize=9, fontName="Helvetica",
    textColor=TEXT_DARK, leading=12, spaceAfter=1, leftIndent=12)

mcq_ans = S("MCQ_Ans",
    fontSize=9, fontName="Helvetica-Bold",
    textColor=GREEN, spaceAfter=8, leftIndent=12)

story = []

# ════════════════════════════════════════════════════════════════════════
# COVER HEADER
# ════════════════════════════════════════════════════════════════════════
cover_data = [[
    Paragraph("PHARMACY PRACTICE - SEMESTER 7", subtitle_style),
    Paragraph("STUDY GUIDE", title_style),
    Paragraph("Role of Pharmacist", S("sub2", fontSize=16, fontName="Helvetica-Bold",
              textColor=ACCENT, alignment=TA_CENTER, spaceAfter=2)),
    Paragraph("B.Pharm | Exam Preparation Notes", subtitle_style),
]]

cover_table = Table(cover_data, colWidths=[doc.width])
cover_table.setStyle(TableStyle([
    ("BACKGROUND",    (0,0), (-1,-1), DARK_BLUE),
    ("TOPPADDING",    (0,0), (-1,-1), 18),
    ("BOTTOMPADDING", (0,0), (-1,-1), 18),
    ("LEFTPADDING",   (0,0), (-1,-1), 20),
    ("RIGHTPADDING",  (0,0), (-1,-1), 20),
    ("ROWBACKGROUNDS",(0,0), (-1,-1), [DARK_BLUE]),
]))
story.append(cover_table)
story.append(Spacer(1, 0.4*cm))

# Quick overview pill badges
overview_items = [
    ["5 Key Roles", "Industry · Research · Academics · Hospitals · Community Pharmacy"],
    ["Subject", "Pharmacy Practice (Sem 7)"],
    ["Purpose", "Exam Long-Answer + MCQ + Viva Prep"],
]
for badge, desc in overview_items:
    badge_data = [[
        Paragraph(f"<b>{badge}</b>", S("badge", fontSize=9, fontName="Helvetica-Bold",
                  textColor=WHITE, alignment=TA_CENTER)),
        Paragraph(desc, S("bdesc", fontSize=9, fontName="Helvetica",
                  textColor=DARK_BLUE)),
    ]]
    bt = Table(badge_data, colWidths=[3.5*cm, doc.width - 3.5*cm])
    bt.setStyle(TableStyle([
        ("BACKGROUND",    (0,0), (0,0), MED_BLUE),
        ("BACKGROUND",    (1,0), (1,0), LIGHT_BLUE),
        ("TOPPADDING",    (0,0), (-1,-1), 5),
        ("BOTTOMPADDING", (0,0), (-1,-1), 5),
        ("LEFTPADDING",   (0,0), (-1,-1), 8),
        ("RIGHTPADDING",  (0,0), (-1,-1), 8),
        ("VALIGN",        (0,0), (-1,-1), "MIDDLE"),
    ]))
    story.append(bt)
    story.append(Spacer(1, 0.15*cm))

story.append(Spacer(1, 0.3*cm))
story.append(HRFlowable(width="100%", thickness=1, color=MID_GRAY))
story.append(Spacer(1, 0.3*cm))

# ════════════════════════════════════════════════════════════════════════
# HELPER: section header banner
# ════════════════════════════════════════════════════════════════════════
def section_header(roman, title, icon=""):
    data = [[Paragraph(f"{roman})  {title}", h1)]]
    t = Table(data, colWidths=[doc.width])
    t.setStyle(TableStyle([
        ("BACKGROUND",    (0,0), (-1,-1), MED_BLUE),
        ("TOPPADDING",    (0,0), (-1,-1), 8),
        ("BOTTOMPADDING", (0,0), (-1,-1), 8),
        ("LEFTPADDING",   (0,0), (-1,-1), 12),
        ("RIGHTPADDING",  (0,0), (-1,-1), 12),
    ]))
    return t

def sub_header(text):
    return Paragraph(text, h2)

def sub2_header(text):
    return Paragraph(text, h3)

def bullet(text):
    return Paragraph(f"• {text}", bullet_style)

def body_para(text):
    return Paragraph(text, body)

def note(text):
    data = [[Paragraph(f"📌 {text}", note_style)]]
    t = Table(data, colWidths=[doc.width])
    t.setStyle(TableStyle([
        ("BACKGROUND",    (0,0), (-1,-1), LIGHT_GREEN),
        ("TOPPADDING",    (0,0), (-1,-1), 5),
        ("BOTTOMPADDING", (0,0), (-1,-1), 5),
        ("LEFTPADDING",   (0,0), (-1,-1), 10),
        ("RIGHTPADDING",  (0,0), (-1,-1), 10),
        ("BOX",           (0,0), (-1,-1), 0.5, GREEN),
    ]))
    return t

def exam_tip(text):
    data = [[Paragraph(f"★ EXAM TIP: {text}", exam_style)]]
    t = Table(data, colWidths=[doc.width])
    t.setStyle(TableStyle([
        ("BACKGROUND",    (0,0), (-1,-1), LIGHT_RED),
        ("TOPPADDING",    (0,0), (-1,-1), 5),
        ("BOTTOMPADDING", (0,0), (-1,-1), 5),
        ("LEFTPADDING",   (0,0), (-1,-1), 10),
        ("RIGHTPADDING",  (0,0), (-1,-1), 10),
        ("BOX",           (0,0), (-1,-1), 0.5, RED),
    ]))
    return t

# ════════════════════════════════════════════════════════════════════════
# I. INDUSTRY
# ════════════════════════════════════════════════════════════════════════
story.append(section_header("I", "Role in Industry"))
story.append(Spacer(1, 0.2*cm))
story.append(body_para(
    "The pharmaceutical industry is one of the largest employers of pharmacists. "
    "Their involvement spans from the birth of a drug idea to the product reaching the market shelf."
))
story.append(Spacer(1, 0.2*cm))

industry_sections = [
    ("A. Drug Development & Formulation", [
        "Work in R&D departments to design new drug formulations - tablets, capsules, syrups, patches, injectables, and biologics.",
        "Study physicochemical properties of drug molecules and select appropriate excipients (binders, fillers, disintegrants, preservatives).",
        "Perform preformulation studies: solubility, stability, compatibility, and polymorphism testing.",
        "Develop innovative drug delivery systems: nanoparticles, liposomes, transdermal patches, controlled-release formulations.",
    ]),
    ("B. Manufacturing", [
        "Supervise large-scale manufacturing processes following GMP (Good Manufacturing Practices) guidelines.",
        "Ensure Standard Operating Procedures (SOPs) are followed at every step of production.",
        "Oversee batch production records, in-process quality checks, and yield calculations.",
        "Manage scale-up from laboratory to pilot plant to commercial-scale production.",
    ]),
    ("C. Quality Control (QC) & Quality Assurance (QA)", [
        "QC pharmacists test raw materials, intermediates, and finished products for identity, purity, potency, and safety.",
        "Perform tests: dissolution, disintegration, content uniformity, sterility, microbial limits, and stability testing.",
        "QA pharmacists develop and maintain quality systems, conduct internal audits, handle deviations and non-conformities.",
        "Ensure compliance with IP (Indian Pharmacopoeia), BP, USP, and ICH guidelines.",
    ]),
    ("D. Regulatory Affairs", [
        "Prepare and file drug registration dossiers for new drug approvals with CDSCO (India), US FDA, and EMA (Europe).",
        "Handle drug licensing, patent applications, and product labeling compliance.",
        "Manage post-approval changes and annual product reviews.",
        "Track changing regulations and ensure company compliance at all times.",
    ]),
    ("E. Pharmacovigilance (Drug Safety)", [
        "Monitor and evaluate post-marketing safety data for approved drugs.",
        "Prepare Periodic Safety Update Reports (PSURs) and report serious adverse events to regulators.",
        "Manage Risk Management Plans (RMPs) for drugs with known serious risks.",
        "Coordinate global safety databases (e.g., Vigibase, Argus Safety).",
    ]),
    ("F. Sales & Marketing", [
        "Work as Medical Representatives (MRs), Product Managers, or Brand Managers.",
        "Educate doctors and healthcare providers about the company's drug portfolio.",
        "Develop promotional literature, drug monographs, and training materials for the sales team.",
        "Ensure marketing materials comply with regulatory guidelines (no off-label promotion).",
    ]),
]

for title, bullets in industry_sections:
    story.append(sub2_header(title))
    for b in bullets:
        story.append(bullet(b))
    story.append(Spacer(1, 0.1*cm))

story.append(exam_tip("Common exam question: 'What is the role of a pharmacist in Quality Control vs Quality Assurance?' - QC = testing product, QA = maintaining the system."))
story.append(Spacer(1, 0.3*cm))

# ════════════════════════════════════════════════════════════════════════
# II. RESEARCH
# ════════════════════════════════════════════════════════════════════════
story.append(PageBreak())
story.append(section_header("II", "Role in Research"))
story.append(Spacer(1, 0.2*cm))
story.append(body_para(
    "Pharmacists are actively involved in scientific research at every level - from bench to bedside. "
    "Research pharmacists bridge the gap between laboratory science and clinical application."
))
story.append(Spacer(1, 0.2*cm))

research_sections = [
    ("A. Drug Discovery Research", [
        "Assist in high-throughput screening of compound libraries to find potential drug candidates.",
        "Conduct SAR (Structure-Activity Relationship) studies to optimize drug molecules.",
        "Work with computational pharmacology tools for in silico drug design and molecular docking.",
        "Identify lead compounds and assist medicinal chemists in structural modifications.",
    ]),
    ("B. Preclinical Research", [
        "Conduct in vitro and in vivo pharmacological studies - testing efficacy, safety, and toxicity.",
        "Perform ADME studies (Absorption, Distribution, Metabolism, Excretion) for new drugs.",
        "Conduct acute, subacute, and chronic toxicity studies in animal models.",
        "Prepare preclinical study reports for IND (Investigational New Drug) applications.",
    ]),
    ("C. Clinical Trials (Phases I-IV)", [
        "Phase I: Manage first-in-human studies - dose escalation, safety, and pharmacokinetics in healthy volunteers.",
        "Phase II: Monitor drug efficacy and dose-response in small patient groups.",
        "Phase III: Oversee large-scale randomized controlled trials for efficacy and safety comparison.",
        "Phase IV: Conduct post-marketing surveillance studies after drug approval.",
        "Manage investigational drug supply - storage, dispensing, accountability, and destruction.",
        "Act as Clinical Research Associate (CRA) or Clinical Research Coordinator (CRC).",
    ]),
    ("D. Pharmacokinetic & Pharmacodynamic Research", [
        "Develop and validate analytical methods (HPLC, LC-MS/MS) to measure drug levels in biological samples.",
        "Build PK/PD models to predict optimal dosing regimens for different patient populations.",
        "Conduct bioavailability and bioequivalence studies - essential for generic drug approvals.",
        "Perform TDM (Therapeutic Drug Monitoring) research for narrow therapeutic index drugs.",
    ]),
    ("E. Publication & Scientific Communication", [
        "Write and publish research papers in peer-reviewed journals (PubMed-indexed).",
        "Prepare systematic reviews and meta-analyses on drug therapies.",
        "Present findings at national and international pharmacy/pharmacology conferences.",
        "File patents for novel formulations, drug delivery systems, or manufacturing processes.",
    ]),
]

for title, bullets in research_sections:
    story.append(sub2_header(title))
    for b in bullets:
        story.append(bullet(b))
    story.append(Spacer(1, 0.1*cm))

story.append(note("Clinical trial phases I-IV is a very common exam topic. Remember: I = Safety, II = Efficacy (small), III = Efficacy (large/comparison), IV = Post-marketing."))
story.append(Spacer(1, 0.3*cm))

# ════════════════════════════════════════════════════════════════════════
# III. ACADEMICS
# ════════════════════════════════════════════════════════════════════════
story.append(PageBreak())
story.append(section_header("III", "Role in Academics"))
story.append(Spacer(1, 0.2*cm))
story.append(body_para(
    "Pharmacists in academia shape the next generation of pharmacy professionals. "
    "They combine teaching, research, and service to advance the pharmacy profession."
))
story.append(Spacer(1, 0.2*cm))

academics_sections = [
    ("A. Teaching & Lecturing", [
        "Teach undergraduate (B.Pharm), postgraduate (M.Pharm), and doctoral (Ph.D) students.",
        "Cover subjects: Pharmacology, Pharmaceutics, Pharmaceutical Chemistry, Pharmacy Practice, Pharmacognosy, Clinical Pharmacy.",
        "Deliver lectures, conduct practicals/labs, organize seminars and workshops.",
        "Use modern teaching tools: problem-based learning (PBL), case studies, simulation labs.",
    ]),
    ("B. Curriculum Development", [
        "Design and update syllabus content in line with PCI (Pharmacy Council of India) guidelines.",
        "Integrate new advances in pharmacotherapy and clinical practice into the curriculum.",
        "Develop case-based learning modules, MCQ banks, and study materials.",
        "Periodically revise curriculum to reflect changes in drug approvals and treatment guidelines.",
    ]),
    ("C. Student Mentorship & Supervision", [
        "Guide students in final-year projects, dissertations, and research work.",
        "Supervise M.Pharm and Ph.D scholars as thesis guide/co-guide.",
        "Mentor students for competitive exams (GPAT, NIPER JEE, USMLE for PharmD).",
        "Provide career guidance for students exploring industry, hospital, or research pathways.",
    ]),
    ("D. Research in Academia", [
        "Conduct funded research projects supported by DST, ICMR, DBT, CSIR, or UGC.",
        "Publish findings in indexed journals, building the institution's research output.",
        "File patents for novel formulations or drug delivery systems.",
        "Establish inter-institutional and industry-academia collaborations.",
    ]),
    ("E. Continuing Pharmacy Education (CPE)", [
        "Organize CMEs (Continuing Medical Education) and CPE programs for practicing pharmacists.",
        "Collaborate with industries, hospitals, and government bodies for skill development workshops.",
        "Update practicing pharmacists about new drugs, treatment guidelines, and technologies.",
        "Conduct training programs for pharmacy technicians and paramedical staff.",
    ]),
    ("F. Administrative Roles", [
        "Serve as HOD (Head of Department), Dean, or Principal of pharmacy institutions.",
        "Handle accreditation processes: NAAC, NBA, and PCI inspections.",
        "Manage institutional regulatory compliance and maintain academic standards.",
        "Represent the institution in professional bodies like IPA (Indian Pharmaceutical Association).",
    ]),
]

for title, bullets in academics_sections:
    story.append(sub2_header(title))
    for b in bullets:
        story.append(bullet(b))
    story.append(Spacer(1, 0.1*cm))

story.append(exam_tip("'What is CPE / CME?' - CPE stands for Continuing Pharmacy Education; it ensures practicing pharmacists stay updated with advances in drug therapy throughout their careers."))
story.append(Spacer(1, 0.3*cm))

# ════════════════════════════════════════════════════════════════════════
# IV. HOSPITALS
# ════════════════════════════════════════════════════════════════════════
story.append(PageBreak())
story.append(section_header("IV", "Role in Hospitals"))
story.append(Spacer(1, 0.2*cm))
story.append(body_para(
    "Hospital pharmacy is the core of Pharmacy Practice. The hospital pharmacist is an integral member of the "
    "multidisciplinary healthcare team. This is the most detailed and exam-heavy section of Pharmacy Practice Sem 7."
))
story.append(Spacer(1, 0.2*cm))

hospital_sections = [
    ("A. Drug Dispensing", [
        "Dispense inpatient (ward) and outpatient prescriptions accurately and promptly.",
        "Verify prescriptions for completeness, legibility, correct dose, route, and frequency.",
        "Manage unit-dose dispensing (UDD) - individual patient doses packed per administration.",
        "Maintain floor stock and ward stock with proper inventory management.",
        "Implement barcode-assisted dispensing to reduce medication errors.",
    ]),
    ("B. Clinical Pharmacy Services", [
        "Participate in medical ward rounds alongside doctors and nurses.",
        "Conduct Medication Therapy Management (MTM) - reviewing each patient's complete drug regimen.",
        "Identify and resolve Drug-Related Problems (DRPs): subtherapeutic dosing, drug-drug interactions, drug-disease contraindications, unnecessary medications.",
        "Perform Therapeutic Drug Monitoring (TDM) for narrow therapeutic index drugs: digoxin, vancomycin, phenytoin, lithium, aminoglycosides.",
        "Provide dosing recommendations for patients with renal/hepatic impairment.",
        "Contribute to patient care plans and document interventions in medical records.",
    ]),
    ("C. Drug Information Services", [
        "Run a Drug Information Centre (DIC) to answer drug-related queries from doctors, nurses, and patients.",
        "Provide information on drug dose, interactions, adverse effects, storage, and availability.",
        "Maintain and update hospital drug formulary - the approved list of drugs for hospital use.",
        "Prepare drug monographs, drug bulletins, and newsletters for the healthcare team.",
        "Access databases like Micromedex, Lexicomp, UpToDate, and WHO drug information.",
    ]),
    ("D. Pharmacovigilance", [
        "Monitor, detect, assess, and report Adverse Drug Reactions (ADRs) in hospital settings.",
        "Use the WHO-Uppsala Monitoring Centre (UMC) causality assessment scale to evaluate ADRs.",
        "Submit ADR reports to the National Pharmacovigilance Programme (PvPI) coordinated by CDSCO.",
        "Educate healthcare staff about identifying, documenting, and reporting ADRs.",
        "Maintain ADR data for hospital-level trend analysis and formulary decisions.",
    ]),
    ("E. Medication Reconciliation", [
        "At admission: compile a complete, accurate list of the patient's current home medications (BPMH - Best Possible Medication History).",
        "At transfer: compare and reconcile medications when a patient moves between wards or units.",
        "At discharge: compare discharge medications with admission medications; resolve discrepancies.",
        "Prevent medication errors due to omissions, duplications, dosing changes, or drug interactions.",
    ]),
    ("F. Sterile Preparations & Compounding", [
        "Prepare IV admixtures, chemotherapy doses (cytotoxics/hazardous drugs) under laminar airflow hoods in a clean room.",
        "Prepare Total Parenteral Nutrition (TPN) solutions with appropriate electrolytes, vitamins, and nutrients.",
        "Compound specialized formulations not commercially available (e.g., pediatric oral liquids from adult tablets).",
        "Ensure aseptic technique and sterility assurance through environmental monitoring and sterility testing.",
    ]),
    ("G. Formulary Management & P&T Committee", [
        "Develop and maintain the hospital drug formulary using evidence-based criteria.",
        "Evaluate new drugs for addition to the formulary based on safety, efficacy, and cost-effectiveness.",
        "Participate in or chair the Pharmacy and Therapeutics (P&T) Committee.",
        "Conduct drug use evaluations (DUEs) to assess appropriateness of drug therapy in the hospital.",
    ]),
    ("H. Antibiotic Stewardship Program (ASP)", [
        "Implement hospital antibiotic stewardship programs to prevent antimicrobial resistance (AMR).",
        "Review antibiotic prescriptions for appropriate drug selection, dose, route, and duration.",
        "Recommend de-escalation from broad-spectrum to narrow-spectrum antibiotics when possible.",
        "Monitor antibiograms (local resistance patterns) and advise empiric antibiotic therapy.",
        "Educate prescribers on rational antibiotic use and infection prevention.",
    ]),
    ("I. Patient Counseling at Discharge", [
        "Counsel patients on all discharge medications: dose, timing, frequency, storage, and side effects.",
        "Explain drug-drug and drug-food interactions relevant to prescribed medications.",
        "Provide written medication summaries, especially for polypharmacy patients.",
        "Emphasize medication adherence - especially for chronic disease patients (hypertension, diabetes, epilepsy).",
        "Arrange follow-up appointments and educate on warning signs requiring urgent medical attention.",
    ]),
]

for title, bullets in hospital_sections:
    story.append(sub2_header(title))
    for b in bullets:
        story.append(bullet(b))
    story.append(Spacer(1, 0.1*cm))

story.append(note("TDM Drugs to remember: Digoxin, Vancomycin, Phenytoin, Lithium, Carbamazepine, Aminoglycosides (gentamicin), Cyclosporine, Theophylline."))
story.append(Spacer(1, 0.2*cm))
story.append(exam_tip("'What is a P&T Committee?' - Pharmacy and Therapeutics Committee decides which drugs go into the hospital formulary. Pharmacist plays a key role in evidence review and recommendations."))
story.append(Spacer(1, 0.3*cm))

# ════════════════════════════════════════════════════════════════════════
# V. COMMUNITY PHARMACY
# ════════════════════════════════════════════════════════════════════════
story.append(PageBreak())
story.append(section_header("V", "Role in Community Pharmacy"))
story.append(Spacer(1, 0.2*cm))
story.append(body_para(
    "The community pharmacist is the most accessible healthcare provider - often the first and most frequent "
    "point of contact for the general public. Nine in 10 people live within 5 km of a community pharmacy."
))
story.append(Spacer(1, 0.2*cm))

community_sections = [
    ("A. Prescription Dispensing", [
        "Receive, verify, and dispense prescription medications accurately.",
        "Screen prescriptions for drug-drug interactions, drug-food interactions, and contraindications.",
        "Check dose appropriateness and clarify with the prescriber if needed.",
        "Maintain dispensing records and prescription registers as required under Drugs & Cosmetics Act.",
        "Implement dispensing software with drug interaction alerts and clinical decision support.",
    ]),
    ("B. OTC Drug Management", [
        "Advise patients on self-medication with OTC products for minor ailments (cold, fever, headache, acidity, allergies).",
        "Prevent OTC drug misuse - especially with analgesics, antihistamines, and cough syrups.",
        "Educate patients about maximum OTC doses and duration limits.",
        "Recommend appropriate OTC alternatives when a prescribed drug is unavailable.",
    ]),
    ("C. Patient Counseling", [
        "Counsel every patient on how to take the medicine (with/without food, time of day).",
        "Explain side effects to expect and how to manage them (e.g., take metronidazole with food).",
        "Advise on proper storage: room temperature, refrigeration, protection from light and moisture.",
        "Warn about specific drug interactions: warfarin-aspirin, metformin-alcohol, MAOIs-tyramine-rich foods.",
        "Provide written instructions for elderly, pediatric caregivers, or patients with low health literacy.",
    ]),
    ("D. Health Screening & Wellness Services", [
        "Offer point-of-care screening services: blood pressure measurement, blood glucose testing, BMI assessment.",
        "Conduct cholesterol screening, INR monitoring (for warfarin patients), and pregnancy tests.",
        "Identify at-risk individuals and refer them to physicians for further evaluation and management.",
        "Provide smoking cessation counseling and nicotine replacement therapy.",
        "Advise on weight management, diet, and lifestyle modification for chronic disease prevention.",
    ]),
    ("E. Chronic Disease Management", [
        "Counsel and monitor patients with diabetes: correct use of insulin, blood glucose monitoring technique, hypoglycemia management.",
        "Hypertension: adherence to antihypertensives, home BP monitoring, dietary sodium restriction.",
        "Asthma/COPD: proper inhaler technique (MDI, DPI, spacer use), trigger avoidance.",
        "Epilepsy: importance of strict dose timing, missed dose protocol, drug interactions with AEDs.",
        "Set up Medication Adherence Programs (MAPs) with follow-up calls and pill organizers.",
    ]),
    ("F. Drug Abuse Prevention", [
        "Prevent prescription forgery and overuse of controlled substances (opioids, benzodiazepines, stimulants).",
        "Monitor prescription patterns for signs of drug-seeking behavior.",
        "Participate in drug de-addiction awareness programs and needle exchange services.",
        "Report suspected misuse or drug diversion to appropriate authorities.",
    ]),
    ("G. Referral System", [
        "Recognize symptoms indicating an emergency or serious illness: chest pain, stroke symptoms, severe allergic reactions.",
        "Refer patients appropriately to GPs, specialists, or emergency departments without delay.",
        "Act as the gateway to the healthcare system - especially in rural and underserved areas.",
        "Provide first-aid advice and oral rehydration therapy (ORS) for gastroenteritis cases.",
    ]),
    ("H. Public Health & Community Education", [
        "Conduct health camps and awareness drives: rational antibiotic use, avoiding self-medication.",
        "Advise on proper disposal of unused and expired medicines (environmental protection).",
        "Promote awareness on vaccine-preventable diseases and immunization schedules.",
        "Collaborate with NGOs and government health programs (NRHM, Ayushman Bharat, Jan Aushadhi).",
        "Participate in national public health campaigns: World Health Day, No Tobacco Day, World Diabetes Day.",
    ]),
]

for title, bullets in community_sections:
    story.append(sub2_header(title))
    for b in bullets:
        story.append(bullet(b))
    story.append(Spacer(1, 0.1*cm))

story.append(exam_tip("'What is Jan Aushadhi?' - Pradhan Mantri Bhartiya Janaushadhi Pariyojana (PMBJP) - government scheme providing quality generic medicines at affordable prices through Jan Aushadhi Kendras."))
story.append(Spacer(1, 0.3*cm))

# ════════════════════════════════════════════════════════════════════════
# SUMMARY TABLE
# ════════════════════════════════════════════════════════════════════════
story.append(PageBreak())
header_data = [[Paragraph("QUICK REVISION - SUMMARY TABLE", S("sumtitle",
    fontSize=13, fontName="Helvetica-Bold", textColor=WHITE, alignment=TA_CENTER))]]
ht = Table(header_data, colWidths=[doc.width])
ht.setStyle(TableStyle([
    ("BACKGROUND",    (0,0), (-1,-1), DARK_BLUE),
    ("TOPPADDING",    (0,0), (-1,-1), 10),
    ("BOTTOMPADDING", (0,0), (-1,-1), 10),
]))
story.append(ht)
story.append(Spacer(1, 0.3*cm))

table_data = [
    [Paragraph("<b>Setting</b>", S("th", fontSize=10, fontName="Helvetica-Bold", textColor=WHITE)),
     Paragraph("<b>Primary Function</b>", S("th", fontSize=10, fontName="Helvetica-Bold", textColor=WHITE)),
     Paragraph("<b>Key Keywords</b>", S("th", fontSize=10, fontName="Helvetica-Bold", textColor=WHITE))],
    [Paragraph("INDUSTRY", S("tc", fontSize=9.5, fontName="Helvetica-Bold", textColor=MED_BLUE)),
     Paragraph("Drug manufacturing, QC/QA, Regulatory affairs, Drug safety", body),
     Paragraph("GMP, CDSCO, QC, QA, GCP, Pharmacovigilance, PSUR", body)],
    [Paragraph("RESEARCH", S("tc", fontSize=9.5, fontName="Helvetica-Bold", textColor=MED_BLUE)),
     Paragraph("Drug discovery, Preclinical & clinical trials, PK/PD studies", body),
     Paragraph("SAR, ADME, Phase I-IV, CRA, Bioequivalence, TDM", body)],
    [Paragraph("ACADEMICS", S("tc", fontSize=9.5, fontName="Helvetica-Bold", textColor=MED_BLUE)),
     Paragraph("Teaching, Mentoring, Research, Curriculum, CPE", body),
     Paragraph("PCI, GPAT, CME, CPE, NAAC, NBA, IPA", body)],
    [Paragraph("HOSPITAL", S("tc", fontSize=9.5, fontName="Helvetica-Bold", textColor=MED_BLUE)),
     Paragraph("Clinical pharmacy, Dispensing, DIC, PV, Stewardship", body),
     Paragraph("TDM, DRP, MTM, ASP, P&T Committee, ADR, PvPI, TPN", body)],
    [Paragraph("COMMUNITY", S("tc", fontSize=9.5, fontName="Helvetica-Bold", textColor=MED_BLUE)),
     Paragraph("OTC dispensing, Counseling, Health screening, Public health", body),
     Paragraph("OTC, MAPs, Jan Aushadhi, NRHM, Ayushman Bharat, ORS", body)],
]

summary_table = Table(table_data, colWidths=[3.5*cm, 7.5*cm, doc.width - 11*cm])
summary_table.setStyle(TableStyle([
    ("BACKGROUND",    (0,0), (-1,0), MED_BLUE),
    ("BACKGROUND",    (0,1), (-1,1), LIGHT_BLUE),
    ("BACKGROUND",    (0,2), (-1,2), WHITE),
    ("BACKGROUND",    (0,3), (-1,3), LIGHT_BLUE),
    ("BACKGROUND",    (0,4), (-1,4), WHITE),
    ("BACKGROUND",    (0,5), (-1,5), LIGHT_BLUE),
    ("TOPPADDING",    (0,0), (-1,-1), 7),
    ("BOTTOMPADDING", (0,0), (-1,-1), 7),
    ("LEFTPADDING",   (0,0), (-1,-1), 8),
    ("RIGHTPADDING",  (0,0), (-1,-1), 8),
    ("VALIGN",        (0,0), (-1,-1), "TOP"),
    ("GRID",          (0,0), (-1,-1), 0.5, MID_GRAY),
    ("ROWBACKGROUNDS",(0,1), (-1,-1), [LIGHT_BLUE, WHITE]),
]))
story.append(summary_table)
story.append(Spacer(1, 0.5*cm))

# ════════════════════════════════════════════════════════════════════════
# MCQ SECTION
# ════════════════════════════════════════════════════════════════════════
mcq_header_data = [[Paragraph("MCQ PRACTICE - EXAM STYLE QUESTIONS", S("mcqtitle",
    fontSize=13, fontName="Helvetica-Bold", textColor=WHITE, alignment=TA_CENTER))]]
mcqht = Table(mcq_header_data, colWidths=[doc.width])
mcqht.setStyle(TableStyle([
    ("BACKGROUND",    (0,0), (-1,-1), GREEN),
    ("TOPPADDING",    (0,0), (-1,-1), 10),
    ("BOTTOMPADDING", (0,0), (-1,-1), 10),
]))
story.append(mcqht)
story.append(Spacer(1, 0.3*cm))

mcqs = [
    ("1. A pharmacist working in the QA department of a pharmaceutical company is primarily responsible for:",
     ["a) Testing finished drug products in the laboratory",
      "b) Developing and maintaining quality management systems and auditing",
      "c) Manufacturing drugs on a large scale",
      "d) Filing drug registration with CDSCO"],
     "Answer: (b) - QA maintains the quality system; QC does the actual product testing."),

    ("2. Which phase of clinical trials is conducted in healthy volunteers to assess safety and pharmacokinetics?",
     ["a) Phase II", "b) Phase III", "c) Phase I", "d) Phase IV"],
     "Answer: (c) - Phase I is first-in-human, conducted in healthy volunteers for safety and PK."),

    ("3. Therapeutic Drug Monitoring (TDM) is most important for which of the following?",
     ["a) Amoxicillin", "b) Paracetamol", "c) Phenytoin", "d) Metformin"],
     "Answer: (c) - Phenytoin has a narrow therapeutic index and requires TDM to avoid toxicity."),

    ("4. The Pharmacy and Therapeutics (P&T) Committee in a hospital is responsible for:",
     ["a) Managing hospital finances",
      "b) Developing and maintaining the hospital drug formulary",
      "c) Conducting clinical trials",
      "d) Prescribing medications to patients"],
     "Answer: (b) - P&T Committee manages the drug formulary based on safety, efficacy, and cost."),

    ("5. Pradhan Mantri Bhartiya Janaushadhi Pariyojana (PMBJP) is related to:",
     ["a) Free surgical services in government hospitals",
      "b) Providing quality generic medicines at affordable prices",
      "c) Drug rehabilitation program",
      "d) National immunization program"],
     "Answer: (b) - Jan Aushadhi Kendras provide affordable generic medicines under PMBJP."),

    ("6. In hospital pharmacy, BPMH stands for:",
     ["a) Best Possible Medical History",
      "b) Best Possible Medication History",
      "c) Basic Pharmacist Medication Handbook",
      "d) Bedside Patient Medication History"],
     "Answer: (b) - BPMH (Best Possible Medication History) is compiled during medication reconciliation at admission."),

    ("7. Antibiotic Stewardship Programs (ASP) in hospitals primarily aim to:",
     ["a) Increase the use of broad-spectrum antibiotics",
      "b) Reduce hospital drug costs only",
      "c) Prevent antimicrobial resistance and optimize antibiotic use",
      "d) Replace all generic antibiotics with branded ones"],
     "Answer: (c) - ASP optimizes antibiotic selection, dose, and duration to prevent AMR."),

    ("8. A pharmacist conducting SAR (Structure-Activity Relationship) studies is involved in:",
     ["a) Community pharmacy",
      "b) Hospital drug information",
      "c) Drug discovery research",
      "d) Clinical trial phase III"],
     "Answer: (c) - SAR studies are performed in drug discovery to optimize molecular structures."),
]

for q, options, answer in mcqs:
    story.append(Paragraph(q, mcq_q))
    for opt in options:
        story.append(Paragraph(opt, mcq_a))
    story.append(Paragraph(answer, mcq_ans))

# ════════════════════════════════════════════════════════════════════════
# IMPORTANT ABBREVIATIONS
# ════════════════════════════════════════════════════════════════════════
story.append(PageBreak())
abbr_header = [[Paragraph("IMPORTANT ABBREVIATIONS & FULL FORMS", S("abbrtitle",
    fontSize=13, fontName="Helvetica-Bold", textColor=WHITE, alignment=TA_CENTER))]]
abbrht = Table(abbr_header, colWidths=[doc.width])
abbrht.setStyle(TableStyle([
    ("BACKGROUND",    (0,0), (-1,-1), colors.HexColor("#6A1B9A")),
    ("TOPPADDING",    (0,0), (-1,-1), 10),
    ("BOTTOMPADDING", (0,0), (-1,-1), 10),
]))
story.append(abbrht)
story.append(Spacer(1, 0.3*cm))

abbr_data = [
    [Paragraph("<b>Abbreviation</b>", S("th2", fontSize=9.5, fontName="Helvetica-Bold", textColor=WHITE)),
     Paragraph("<b>Full Form</b>", S("th2", fontSize=9.5, fontName="Helvetica-Bold", textColor=WHITE)),
     Paragraph("<b>Context</b>", S("th2", fontSize=9.5, fontName="Helvetica-Bold", textColor=WHITE))],
    ["GMP", "Good Manufacturing Practices", "Industry"],
    ["QC / QA", "Quality Control / Quality Assurance", "Industry"],
    ["CDSCO", "Central Drugs Standard Control Organisation", "Regulatory (India)"],
    ["PSUR", "Periodic Safety Update Report", "Pharmacovigilance"],
    ["ADME", "Absorption, Distribution, Metabolism, Excretion", "Research / PK"],
    ["SAR", "Structure-Activity Relationship", "Drug Discovery"],
    ["CRA / CRC", "Clinical Research Associate / Coordinator", "Clinical Trials"],
    ["TDM", "Therapeutic Drug Monitoring", "Hospital Pharmacy"],
    ["DRP", "Drug-Related Problem", "Clinical Pharmacy"],
    ["MTM", "Medication Therapy Management", "Hospital/Community"],
    ["ASP", "Antibiotic Stewardship Program", "Hospital Pharmacy"],
    ["P&T", "Pharmacy and Therapeutics Committee", "Hospital Pharmacy"],
    ["DIC", "Drug Information Centre", "Hospital Pharmacy"],
    ["TPN", "Total Parenteral Nutrition", "Hospital Pharmacy"],
    ["PvPI", "Pharmacovigilance Programme of India", "Pharmacovigilance"],
    ["ADR", "Adverse Drug Reaction", "Pharmacovigilance"],
    ["BPMH", "Best Possible Medication History", "Medication Reconciliation"],
    ["CPE", "Continuing Pharmacy Education", "Academics"],
    ["PCI", "Pharmacy Council of India", "Academics/Regulation"],
    ["MAPs", "Medication Adherence Programs", "Community Pharmacy"],
    ["OTC", "Over-The-Counter", "Community Pharmacy"],
    ["PMBJP", "Pradhan Mantri Bhartiya Janaushadhi Pariyojana", "Community/Govt"],
    ["AMR", "Antimicrobial Resistance", "Antibiotic Stewardship"],
    ["IPA", "Indian Pharmaceutical Association", "Professional Body"],
]

formatted_abbr = []
for i, row in enumerate(abbr_data):
    if i == 0:
        formatted_abbr.append(row)
    else:
        formatted_abbr.append([
            Paragraph(row[0], S(f"ac{i}", fontSize=9, fontName="Helvetica-Bold", textColor=MED_BLUE)),
            Paragraph(row[1], body),
            Paragraph(row[2], S(f"ctx{i}", fontSize=9, fontName="Helvetica-Oblique", textColor=GREEN)),
        ])

abbr_table = Table(formatted_abbr, colWidths=[3*cm, 9.5*cm, doc.width - 12.5*cm])
abbr_table.setStyle(TableStyle([
    ("BACKGROUND",    (0,0), (-1,0), colors.HexColor("#6A1B9A")),
    ("ROWBACKGROUNDS",(0,1), (-1,-1), [LIGHT_BLUE, WHITE]),
    ("TOPPADDING",    (0,0), (-1,-1), 5),
    ("BOTTOMPADDING", (0,0), (-1,-1), 5),
    ("LEFTPADDING",   (0,0), (-1,-1), 8),
    ("RIGHTPADDING",  (0,0), (-1,-1), 8),
    ("VALIGN",        (0,0), (-1,-1), "TOP"),
    ("GRID",          (0,0), (-1,-1), 0.4, MID_GRAY),
]))
story.append(abbr_table)
story.append(Spacer(1, 0.5*cm))

# ════════════════════════════════════════════════════════════════════════
# MIND MAP / FLOW DIAGRAM (text-based)
# ════════════════════════════════════════════════════════════════════════
mindmap_header = [[Paragraph("MIND MAP - ROLE OF PHARMACIST", S("mmtitle",
    fontSize=13, fontName="Helvetica-Bold", textColor=WHITE, alignment=TA_CENTER))]]
mmht = Table(mindmap_header, colWidths=[doc.width])
mmht.setStyle(TableStyle([
    ("BACKGROUND",    (0,0), (-1,-1), ACCENT),
    ("TOPPADDING",    (0,0), (-1,-1), 10),
    ("BOTTOMPADDING", (0,0), (-1,-1), 10),
]))
story.append(mmht)
story.append(Spacer(1, 0.3*cm))

mind_map_data = [
    ["INDUSTRY", "Manufacturing → QC/QA → Regulatory → Pharmacovigilance → Marketing"],
    ["RESEARCH", "Drug Discovery → Preclinical → Clinical Trials (I-IV) → PK/PD → Publication"],
    ["ACADEMICS", "Teaching → Curriculum → Mentorship → Research → CPE → Admin Roles"],
    ["HOSPITAL", "Dispensing → Clinical Pharmacy → Drug Info → PV → TDM → ASP → Counseling"],
    ["COMMUNITY", "Dispensing → OTC → Counseling → Screening → Chronic Mgmt → Public Health"],
]

colours_mm = [MED_BLUE, GREEN, colors.HexColor("#6A1B9A"), RED, ACCENT]
text_cols = [WHITE, WHITE, WHITE, WHITE, DARK_BLUE]

for idx, (role, flow) in enumerate(mind_map_data):
    row = [[
        Paragraph(role, S(f"mm_r{idx}", fontSize=10, fontName="Helvetica-Bold",
                  textColor=text_cols[idx], alignment=TA_CENTER)),
        Paragraph(flow, S(f"mm_f{idx}", fontSize=9, fontName="Helvetica",
                  textColor=TEXT_DARK, leading=13)),
    ]]
    rt = Table(row, colWidths=[3*cm, doc.width - 3*cm])
    rt.setStyle(TableStyle([
        ("BACKGROUND",    (0,0), (0,0), colours_mm[idx]),
        ("BACKGROUND",    (1,0), (1,0), LIGHT_GRAY),
        ("TOPPADDING",    (0,0), (-1,-1), 8),
        ("BOTTOMPADDING", (0,0), (-1,-1), 8),
        ("LEFTPADDING",   (0,0), (-1,-1), 8),
        ("RIGHTPADDING",  (0,0), (-1,-1), 8),
        ("VALIGN",        (0,0), (-1,-1), "MIDDLE"),
        ("BOX",           (0,0), (-1,-1), 0.5, MID_GRAY),
    ]))
    story.append(rt)
    story.append(Spacer(1, 0.12*cm))

# ════════════════════════════════════════════════════════════════════════
# FOOTER NOTE
# ════════════════════════════════════════════════════════════════════════
story.append(Spacer(1, 0.5*cm))
story.append(HRFlowable(width="100%", thickness=1, color=MID_GRAY))
story.append(Spacer(1, 0.2*cm))
footer_data = [[
    Paragraph(
        "Pharmacy Practice - Semester 7  |  B.Pharm Study Guide  |  Role of Pharmacist  |  Prepared for Exam Preparation",
        S("footer", fontSize=8, fontName="Helvetica-Oblique", textColor=colors.gray, alignment=TA_CENTER)
    )
]]
ft = Table(footer_data, colWidths=[doc.width])
story.append(ft)

# ════════════════════════════════════════════════════════════════════════
# BUILD
# ════════════════════════════════════════════════════════════════════════
doc.build(story)
print(f"PDF created successfully: {OUTPUT}")

const pptxgen = require("pptxgenjs");

const pres = new pptxgen();
pres.layout = "LAYOUT_16x9";
pres.title = "Role of Pharmacist";
pres.author = "B.Pharm Semester 7";

// ── Color Palette ─────────────────────────────────────────────────────
const DARK_BLUE  = "1A3A5C";
const MED_BLUE   = "2563A8";
const LIGHT_BLUE = "D6E4F7";
const ACCENT     = "F4A81D";
const WHITE      = "FFFFFF";
const LIGHT_GRAY = "F0F4FA";
const MID_GRAY   = "CCCCCC";
const TEXT_DARK  = "1C1C1C";
const GREEN      = "1E7A44";
const LIGHT_GREEN= "D6F0E0";
const RED        = "C0392B";
const LIGHT_RED  = "FDECEA";
const PURPLE     = "6A1B9A";

// ════════════════════════════════════════════════════════════════════════
// SLIDE 1 — TITLE SLIDE
// ════════════════════════════════════════════════════════════════════════
{
  const slide = pres.addSlide();

  // Dark blue full background
  slide.addShape(pres.ShapeType.rect, { x: 0, y: 0, w: 10, h: 5.625, fill: { color: DARK_BLUE } });

  // Accent bar top
  slide.addShape(pres.ShapeType.rect, { x: 0, y: 0, w: 10, h: 0.18, fill: { color: ACCENT } });

  // Accent bar bottom
  slide.addShape(pres.ShapeType.rect, { x: 0, y: 5.445, w: 10, h: 0.18, fill: { color: ACCENT } });

  // Decorative circle top-right
  slide.addShape(pres.ShapeType.ellipse, { x: 7.8, y: -0.8, w: 2.5, h: 2.5, fill: { color: MED_BLUE }, line: { color: MED_BLUE } });

  // Decorative circle bottom-left
  slide.addShape(pres.ShapeType.ellipse, { x: -0.5, y: 4.3, w: 1.8, h: 1.8, fill: { color: MED_BLUE }, line: { color: MED_BLUE } });

  // Subject label
  slide.addText("PHARMACY PRACTICE — SEMESTER 7", {
    x: 0.5, y: 1.0, w: 9, h: 0.4,
    fontSize: 11, color: ACCENT, bold: true, align: "center",
    charSpacing: 3, fontFace: "Calibri"
  });

  // Main title
  slide.addText("Role of Pharmacist", {
    x: 0.5, y: 1.55, w: 9, h: 1.1,
    fontSize: 40, color: WHITE, bold: true, align: "center", fontFace: "Calibri"
  });

  // Subtitle
  slide.addText("Industry  |  Research  |  Academics  |  Hospital  |  Community", {
    x: 0.5, y: 2.75, w: 9, h: 0.45,
    fontSize: 13, color: LIGHT_BLUE, align: "center", fontFace: "Calibri"
  });

  // Divider line
  slide.addShape(pres.ShapeType.rect, { x: 3.5, y: 3.35, w: 3, h: 0.04, fill: { color: ACCENT } });

  // Presenter info
  slide.addText("B.Pharm  |  Seminar Presentation  |  2026", {
    x: 0.5, y: 3.6, w: 9, h: 0.35,
    fontSize: 11, color: MID_GRAY, align: "center", italic: true, fontFace: "Calibri"
  });
}

// ════════════════════════════════════════════════════════════════════════
// SLIDE 2 — OVERVIEW / AGENDA
// ════════════════════════════════════════════════════════════════════════
{
  const slide = pres.addSlide();
  slide.addShape(pres.ShapeType.rect, { x: 0, y: 0, w: 10, h: 5.625, fill: { color: LIGHT_GRAY } });
  slide.addShape(pres.ShapeType.rect, { x: 0, y: 0, w: 10, h: 0.9, fill: { color: DARK_BLUE } });
  slide.addShape(pres.ShapeType.rect, { x: 0, y: 0.9, w: 10, h: 0.07, fill: { color: ACCENT } });

  slide.addText("Overview", {
    x: 0.4, y: 0.1, w: 9, h: 0.7,
    fontSize: 26, color: WHITE, bold: true, fontFace: "Calibri"
  });

  // 5 role cards in a row
  const roles = [
    { label: "I", title: "Industry", color: MED_BLUE },
    { label: "II", title: "Research", color: GREEN },
    { label: "III", title: "Academics", color: PURPLE },
    { label: "IV", title: "Hospital", color: RED },
    { label: "V", title: "Community", color: ACCENT },
  ];

  roles.forEach((role, i) => {
    const x = 0.3 + i * 1.9;
    const textColor = role.color === ACCENT ? TEXT_DARK : WHITE;
    slide.addShape(pres.ShapeType.rect, {
      x, y: 1.3, w: 1.7, h: 1.5,
      fill: { color: role.color }, line: { color: role.color },
      shadow: { type: "outer", blur: 5, offset: 2, angle: 45, color: "888888", opacity: 0.3 }
    });
    slide.addText(role.label, {
      x, y: 1.35, w: 1.7, h: 0.6,
      fontSize: 22, color: textColor, bold: true, align: "center", fontFace: "Calibri"
    });
    slide.addText(role.title, {
      x, y: 1.95, w: 1.7, h: 0.7,
      fontSize: 12, color: textColor, bold: true, align: "center", fontFace: "Calibri"
    });
  });

  // What is a Pharmacist?
  slide.addShape(pres.ShapeType.rect, { x: 0.3, y: 3.1, w: 9.4, h: 1.9, fill: { color: LIGHT_BLUE }, line: { color: MED_BLUE, pt: 1 } });
  slide.addText([
    { text: "What is a Pharmacist?\n", options: { bold: true, color: DARK_BLUE, fontSize: 12, breakLine: true } },
    { text: "A pharmacist is a highly trained medication expert who bridges the gap between the science of drugs and the needs of patients. They work across 5 major settings: pharmaceutical industry, research, academic institutions, hospitals, and community pharmacies.", options: { color: TEXT_DARK, fontSize: 11 } }
  ], { x: 0.5, y: 3.2, w: 9.0, h: 1.7, fontFace: "Calibri" });
}

// ════════════════════════════════════════════════════════════════════════
// SLIDE 3 — ROLE IN INDUSTRY
// ════════════════════════════════════════════════════════════════════════
{
  const slide = pres.addSlide();
  slide.addShape(pres.ShapeType.rect, { x: 0, y: 0, w: 10, h: 5.625, fill: { color: WHITE } });
  slide.addShape(pres.ShapeType.rect, { x: 0, y: 0, w: 0.18, h: 5.625, fill: { color: MED_BLUE } });
  slide.addShape(pres.ShapeType.rect, { x: 0, y: 0, w: 10, h: 0.9, fill: { color: MED_BLUE } });
  slide.addShape(pres.ShapeType.rect, { x: 0, y: 0.9, w: 10, h: 0.06, fill: { color: ACCENT } });

  slide.addText("I.  Role in Industry", {
    x: 0.4, y: 0.08, w: 8, h: 0.72,
    fontSize: 26, color: WHITE, bold: true, fontFace: "Calibri"
  });
  slide.addText("Pharmaceutical Industry", {
    x: 0.4, y: 0.08, w: 9.3, h: 0.72,
    fontSize: 13, color: LIGHT_BLUE, align: "right", fontFace: "Calibri"
  });

  const items = [
    ["Drug Dev & Formulation", "Designs tablets, capsules, injectables; preformulation studies (solubility, stability)"],
    ["Manufacturing (GMP)", "Oversees batch production following Good Manufacturing Practices and SOPs"],
    ["QC / QA", "QC: Tests product purity & potency  |  QA: Maintains quality systems & audits"],
    ["Regulatory Affairs", "Files drug dossiers with CDSCO/FDA; manages licensing & labeling compliance"],
    ["Pharmacovigilance", "Monitors drug safety post-market; prepares PSURs; manages Risk Management Plans"],
    ["Sales & Marketing", "Works as Medical Representative, Product Manager; develops promotional materials"],
  ];

  items.forEach(([title, desc], i) => {
    const y = 1.1 + i * 0.73;
    slide.addShape(pres.ShapeType.rect, { x: 0.3, y, w: 2.3, h: 0.6, fill: { color: LIGHT_BLUE }, line: { color: MED_BLUE, pt: 0.5 } });
    slide.addText(title, { x: 0.35, y: y + 0.03, w: 2.2, h: 0.55, fontSize: 9.5, color: MED_BLUE, bold: true, align: "center", fontFace: "Calibri", valign: "middle" });
    slide.addText(desc, { x: 2.75, y: y + 0.03, w: 7.0, h: 0.55, fontSize: 10, color: TEXT_DARK, fontFace: "Calibri", valign: "middle" });
  });

  slide.addText("Key: GMP | CDSCO | QC | QA | PSUR | Pharmacovigilance", {
    x: 0.3, y: 5.25, w: 9.4, h: 0.3,
    fontSize: 9, color: MED_BLUE, bold: true, italic: true, fontFace: "Calibri"
  });
}

// ════════════════════════════════════════════════════════════════════════
// SLIDE 4 — ROLE IN RESEARCH
// ════════════════════════════════════════════════════════════════════════
{
  const slide = pres.addSlide();
  slide.addShape(pres.ShapeType.rect, { x: 0, y: 0, w: 10, h: 5.625, fill: { color: WHITE } });
  slide.addShape(pres.ShapeType.rect, { x: 0, y: 0, w: 0.18, h: 5.625, fill: { color: GREEN } });
  slide.addShape(pres.ShapeType.rect, { x: 0, y: 0, w: 10, h: 0.9, fill: { color: GREEN } });
  slide.addShape(pres.ShapeType.rect, { x: 0, y: 0.9, w: 10, h: 0.06, fill: { color: ACCENT } });

  slide.addText("II.  Role in Research", {
    x: 0.4, y: 0.08, w: 8, h: 0.72,
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    ["Preclinical Research", "In vitro & in vivo studies; ADME profiling; acute & chronic toxicity testing"],
    ["Clinical Trials (I-IV)", "Manages investigational drug supply; monitors ADRs; works as CRA/CRC"],
    ["PK/PD Studies", "Develops analytical methods (HPLC, LC-MS/MS); bioavailability & bioequivalence"],
    ["Scientific Communication", "Publishes research papers; systematic reviews; patent filing; conference presentations"],
  ];

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  });
}

// ════════════════════════════════════════════════════════════════════════
// SLIDE 5 — ROLE IN ACADEMICS
// ════════════════════════════════════════════════════════════════════════
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  const cards = [
    { title: "Teaching", desc: "Lectures B.Pharm, M.Pharm, Ph.D students in Pharmacology, Pharmaceutics, Pharmacy Practice etc." },
    { title: "Curriculum Dev", desc: "Designs syllabus per PCI guidelines; develops case-based modules, MCQ banks" },
    { title: "Mentorship", desc: "Guides project work, dissertations, Ph.D research; preps students for GPAT/NIPER" },
    { title: "Research", desc: "Funded projects (DST, ICMR, DBT); publishes in indexed journals; files patents" },
    { title: "CPE / CME", desc: "Organizes Continuing Pharmacy Education programs to update practicing pharmacists" },
    { title: "Admin Roles", desc: "Serves as HOD, Dean, or Principal; handles NAAC/NBA accreditation" },
  ];

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      x, y, w: 3.0, h: 1.75,
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}

// ════════════════════════════════════════════════════════════════════════
// SLIDE 6 — ROLE IN HOSPITALS
// ════════════════════════════════════════════════════════════════════════
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    ["Drug Dispensing", "Inpatient/outpatient prescriptions; unit-dose dispensing; barcode-assisted dispensing"],
    ["Clinical Pharmacy", "Ward rounds; Medication Therapy Management (MTM); identifies Drug-Related Problems (DRPs)"],
    ["TDM", "Monitors narrow therapeutic index drugs: Digoxin, Vancomycin, Phenytoin, Lithium"],
    ["Drug Information", "Runs Drug Information Centre (DIC); answers drug queries; updates hospital formulary"],
    ["Pharmacovigilance", "Detects & reports ADRs to PvPI (National Pharmacovigilance Programme of India)"],
    ["Med. Reconciliation", "Compiles BPMH at admission; resolves discrepancies at transfer and discharge"],
    ["Sterile Preparation", "Prepares IV admixtures, chemotherapy, TPN in laminar airflow (aseptic technique)"],
    ["Antibiotic Stewardship", "Leads ASP to prevent AMR; reviews antibiotic appropriateness; recommends de-escalation"],
  ];

  items.forEach(([title, desc], i) => {
    const col = i % 2;
    const row = Math.floor(i / 2);
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    const y = 1.08 + row * 1.06;
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    fontSize: 9, color: RED, bold: true, italic: true, fontFace: "Calibri"
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// ════════════════════════════════════════════════════════════════════════
// SLIDE 7 — ROLE IN COMMUNITY PHARMACY
// ════════════════════════════════════════════════════════════════════════
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  slide.addShape(pres.ShapeType.rect, { x: 0, y: 0.9, w: 10, h: 0.06, fill: { color: DARK_BLUE } });

  slide.addText("V.  Role in Community Pharmacy", {
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    ["Prescription Dispensing", "Verifies & dispenses Rx; screens interactions; maintains dispensing records"],
    ["OTC Management", "Advises on self-medication; prevents misuse of analgesics, antihistamines"],
    ["Patient Counseling", "Dose, timing, side effects, storage, drug-food interactions; written instructions"],
    ["Health Screening", "BP monitoring, blood glucose, BMI, cholesterol; refers at-risk patients to doctors"],
    ["Chronic Disease Mgmt", "Counsels diabetics (insulin use), asthmatics (inhaler technique), hypertensives"],
    ["Drug Abuse Prevention", "Prevents Rx forgery; monitors controlled substances; de-addiction awareness"],
    ["Referral System", "Recognizes emergencies; refers to GP/specialist; first gateway to healthcare"],
    ["Public Health Education", "Antibiotic awareness; medicine disposal; collaborates with Jan Aushadhi/NRHM"],
  ];

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// ════════════════════════════════════════════════════════════════════════
// SLIDE 8 — SUMMARY TABLE
// ════════════════════════════════════════════════════════════════════════
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    ["RESEARCH",   "Drug Discovery · Preclinical · Clinical Trials",     "ADME, SAR, Phase I-IV, CRA, BE"],
    ["ACADEMICS",  "Teaching · Mentorship · Research · CPE",             "PCI, GPAT, CME, NAAC, IPA"],
    ["HOSPITAL",   "Clinical Pharmacy · TDM · Drug Info · Stewardship",  "TDM, DRP, MTM, ASP, PvPI, TPN"],
    ["COMMUNITY",  "Dispensing · Counseling · Screening · Public Health","OTC, MAPs, Jan Aushadhi, NRHM"],
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// ════════════════════════════════════════════════════════════════════════
// SLIDE 9 — CONCLUSION + THANK YOU
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// ════════════════════════════════════════════════════════════════════════
// WRITE FILE
// ════════════════════════════════════════════════════════════════════════
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