1. Colonoscopy
Definition: A procedure in which a flexible tube with a camera, called a colonoscope, is passed through the anus to examine the rectum and entire large intestine.
Uses / indications
- Screening for colorectal cancer
- Detecting and removing polyps
- Finding cause of rectal bleeding, chronic diarrhea, anemia, or altered bowel habits
- Taking biopsy specimens
- Monitoring inflammatory bowel disease
Preparation
- Explain procedure and obtain informed consent
- Check allergy, comorbidities, anticoagulants, diabetes medicines, and baseline vital signs
- Clear-liquid diet and prescribed bowel preparation are required
- Keep patient NPO as ordered
- Establish IV access and prepare for sedation
Nursing care after procedure
- Monitor pulse, BP, SpO₂, consciousness, and abdominal pain/distension
- Do not give oral fluids until fully awake and gag reflex is normal if sedation used
- Advise no driving, alcohol, or important decisions for 24 hours after sedation
- Observe for rectal bleeding, severe abdominal pain, fever, dizziness, or vomiting. Report urgently as these can indicate perforation or bleeding.
Complications: Bleeding, perforation, sedation-related respiratory depression, abdominal discomfort, and infection are uncommon. Colonoscopy is contraindicated or deferred in shock and known bowel perforation until stabilized.
Text reference: Yamada's Textbook of Gastroenterology, section “Contraindications to colonoscopy.”
2. ERCP
Full form: Endoscopic Retrograde Cholangiopancreatography.
Definition: ERCP is an endoscopic procedure in which a scope is passed through the mouth into the duodenum. Contrast dye is injected into the bile and pancreatic ducts, and X-ray imaging is used. It is mainly done for treatment, not only diagnosis.
Uses / indications
- Removal of common bile duct stones
- Relief of bile duct obstruction or jaundice
- Biliary or pancreatic stent insertion
- Treatment of strictures
- Bile leak management
- Drainage in selected cases of cholangitis
Preparation
- Check informed consent and NPO status
- Review coagulation profile, platelet count, liver function tests, and renal function as ordered
- Ask about allergy to contrast agents/medicines and anticoagulant use
- Establish IV access; prepare for sedation or anesthesia
- Give prescribed antibiotics, analgesics, or prophylactic medicines
Nursing care after procedure
- Monitor vital signs, oxygen saturation, level of consciousness, and pain
- Observe for abdominal pain, nausea/vomiting, fever/chills, bleeding, or hypotension
- Keep patient NPO until awake and able to swallow safely
- Inform the doctor urgently if severe epigastric pain radiating to the back occurs, as this may suggest pancreatitis
Main complications
- Post-ERCP pancreatitis: most common
- Bleeding, especially after sphincterotomy
- Cholangitis or infection
- Perforation
- Sedation-related respiratory or cardiac complications
ERCP can provide biliary decompression, stone retrieval, and stent placement.
Text reference: Yamada's Textbook of Gastroenterology, section “Endoscopic retrograde cholangiopancreatography”; Clinical Gastrointestinal Endoscopy, section “Complications.”
3. Endoscopy (Upper GI Endoscopy / OGD / EGD)
Definition: Upper gastrointestinal endoscopy is a procedure in which a flexible camera tube is introduced through the mouth to inspect the esophagus, stomach, and first part of the duodenum.
Uses / indications
- Dysphagia or painful swallowing
- Persistent vomiting or upper abdominal pain
- Upper GI bleeding, hematemesis, or melena
- Suspected peptic ulcer or gastritis
- Detection of esophageal varices, tumors, or foreign body
- Biopsy for conditions such as gastritis, celiac disease, or suspected malignancy
- Therapeutic procedures such as injection/clipping of bleeding ulcers or variceal banding
Preparation
- Explain procedure and obtain consent
- Keep patient NPO for the prescribed period, usually 6-8 hours for solids
- Check allergies, denture removal, medications, anticoagulants, and baseline vital signs
- Ensure IV access if sedation is planned
- Give local throat anesthetic and/or sedation as prescribed
Nursing care after procedure
- Place patient in left lateral position during procedure
- Monitor airway, breathing, circulation, SpO₂, pulse, BP, and consciousness
- After procedure, keep NPO until gag reflex returns
- Start sips of water, then diet, as ordered
- Advise no driving for 24 hours if sedated
- Report chest pain, severe abdominal pain, fever, dyspnea, hematemesis, or persistent vomiting
Complications: Sore throat, aspiration, bleeding after biopsy/therapy, perforation, and sedation-related respiratory depression.
Viva point: Upper GI endoscopy is also called esophagogastroduodenoscopy (EGD) or oesophagogastroduodenoscopy (OGD).
Text reference: Fischer's Mastery of Surgery, section “Endoscopic Anatomy of Upper Gastrointestinal Tract.”
4. Liver Biopsy
Definition: Liver biopsy is removal of a small piece of liver tissue for microscopic examination. It helps identify the cause and severity of liver disease.
Types
- Percutaneous liver biopsy: needle inserted through the skin, usually under ultrasound guidance.
- Transjugular liver biopsy: needle passed through the internal jugular vein into a hepatic vein. Preferred when there is ascites or increased bleeding risk.
- Laparoscopic biopsy: done during laparoscopy in selected cases.
Uses / indications
- Diagnosis of unexplained liver disease
- Assessment of fibrosis and cirrhosis
- Evaluation of hepatitis, fatty liver disease, autoimmune liver disease, infiltrative disease, or liver masses
- Assessment before or after liver transplantation in selected patients
Preparation
- Explain procedure and obtain written informed consent
- Check platelet count, PT/INR, blood group, hemoglobin, and liver function tests
- Review anticoagulant/antiplatelet medicines and withhold only as prescribed
- Keep patient NPO as ordered
- Record baseline vital signs and ensure IV access
- Ask the patient to empty the bladder before the procedure
Nursing care after percutaneous biopsy
- Position patient as ordered, commonly on the right side after biopsy to apply pressure at the puncture area
- Monitor vital signs frequently, especially pulse and BP
- Observe the biopsy site for bleeding
- Assess for right upper abdominal pain or right shoulder pain
- Maintain bed rest for the prescribed observation period
- Avoid heavy lifting and strenuous activity for the period advised by the clinician
Complications
- Pain at biopsy site or right shoulder
- Bleeding or hemoperitoneum
- Hypotension/shock due to internal bleeding
- Bile leak, infection, or injury to adjacent organs, rarely
- Pneumothorax, rarely, if the pleura is injured
Viva point: Significant ascites, prolonged INR, thrombocytopenia, or coagulopathy may make percutaneous biopsy unsafe. In such patients, the transjugular route is often preferred because it avoids puncturing the liver capsule and reduces risk of bleeding into the peritoneal cavity.
Text reference: Harrison’s Principles of Internal Medicine, section “Other Diagnostic Tests”; Yamada's Textbook of Gastroenterology, section “Transjugular liver biopsy.”