Paracetamol 250 mg/5 ml, 5 ml TDS for a 15 kg child
Short answer: YES, it is acceptable - but read the details below.
Dose Calculation
| Parameter | Value |
|---|
| Child's weight | 15 kg |
| Dose given | 5 ml = 250 mg per dose |
| Dose per kg | 250 ÷ 15 = 16.7 mg/kg/dose |
| Frequency | TDS = 3 times daily |
| Total daily dose | 750 mg/day = 50 mg/kg/day |
Is It Within Safe Range?
Standard oral paracetamol dose:
- Per dose: 10-15 mg/kg (commonly used range)
- Maximum single dose: up to 20 mg/kg loading in some protocols
- Maximum daily dose: 60 mg/kg/day (general), up to 75 mg/kg/day for post-operative pain (BNFC)
Your dose of 16.7 mg/kg/dose is at the upper end of the standard range but well within safe limits.
Your total daily dose of 50 mg/kg/day is well within the maximum of 60 mg/kg/day.
- Park's Textbook of Preventive Medicine confirms: paracetamol in children 10-15 mg/kg/dose, maximum 100 mg/kg/day
- NHS guidance for the 250 mg/5 ml formulation is for children aged 6 years and above - at 15 kg, the child's age matters
Age Consideration - IMPORTANT
The 250 mg/5 ml ("Six plus") formulation is intended for children 6 years and over per NHS/UK guidelines.
- A 15 kg child is typically around 2-3 years of age
- At this age, the 120 mg/5 ml suspension is the standard formulation
- For a 15 kg child aged ~2-3 years: correct dose would be 150-225 mg per dose (10-15 mg/kg x 15 kg)
- With 120 mg/5 ml: 6-9 ml per dose would be appropriate
However, if this is an older/smaller child (6+ years, 15 kg), the dose is fine.
Summary
| Check | Result |
|---|
| Dose per kg (16.7 mg/kg) | Safe - within range |
| Total daily dose (50 mg/kg/day) | Safe - below 60 mg/kg/day max |
| Formulation (250 mg/5 ml) for ~2-3 yr old | Caution - this formulation is usually for 6+ years; consider 120 mg/5 ml syrup |
| TDS frequency | Fine - 4 times daily is also acceptable if needed |
Bottom line: The dose is pharmacologically safe for a 15 kg child. If the child is indeed 6+ years and small for age, it is perfectly fine. If the child is a toddler (~2-3 years), consider switching to the 120 mg/5 ml suspension and giving 6-7.5 ml TDS instead, as that is the age-appropriate formulation.