You are answering a USMLE-style medical question. Question: A 4-month-old boy is brought to the pediatrician by his parents. He presents to the pediatric ward with fever, dyspnea, and cough, which he developed 3 days ago. His mother also reports he had poor weight gain despite a good appetite during the past 2 months as well as frequent stools with an unpleasant smell. He was born at 29 weeks via spontaneous vaginal delivery. He is meeting all of his milestones and is up to date with all vaccines. The child is breastfed exclusively. His blood pressure is 80/50 mm Hg, the heart rate is 109/min, the respiratory rate is 29/min, and the temperature is 39.1°C (102.4°F). The patient’s weight is between the 5th and 10th percentile. His length is between the 50th and 75th percentile. The patient is sluggish and reacts torpidly to examination. His skin is pale and dry with decreased turgor and elasticity. On auscultation, there are diminished vesicular sounds and disseminated moist rales at the bases of both lungs. Heart sounds are normal. The abdomen is distended without palpable masses. The patient’s blood analysis shows the following findings: Complete blood count Erythrocytes 3.3 x 106/mm3 Hb 12 g/dL Total leukocyte count 17,500/mm3 Neutrophils 59% Lymphocytes 32% Eosinophils 3% Monocytes 6% Basophils 0 Platelet count 232,000/mm3 Sputum culture grows Pseudomonas aeruginosa. A sweat test shows chloride concentration of 85 mEq/L (elevated). Which of the following is involved in the pathogenesis of this patient’s symptoms? Options: A) Neutrophil elastase damages lung tissue due to lack of alpha-1-antitrypsin. B) Abnormal CFTR protein C) Electron transport chain in mitochondria is disrupted due to lack of glycerol-3-phosphate dehydrogenase. D) Due to mutations in dynein, the ciliary epithelium fails to provide appropriate mucociliary clearance. Reply with ONLY the letter of the correct answer (A, B, C, or D). No explanation.