Suggested headings for each drug A) Introduction a. Drug class b. Why it was developed c. Potential advantage over existing drugs in that drug class B) Mechanism of action a.Receptor or enzyme involved b. Principal site of action and pathways c. Principal pharmacological effects C) Pharmacokinetics a. Onset and duration b. Metabolism and elimination c. Context-sensitive half-time d. Effect of renal or hepatic dysfunction D) Clinical uses in anaesthesia a. Induction dose (loading) and maintenance dose bolus/ infusion b. Procedural sedation c. Analgesia d. Intensive care e. For Postoperative pain or nausea and vomiting f. Use in children E) Dose modifications in a. elderly b. obese c. critically ill patients F) Advantages a. Rapid onset or rapid recovery or both b. Improvement in safety c. Haemodynamic stability d. Respiratory safety e. Organ-independent metabolism or dependent f. Availability of reversal agent (antidote) g. Opioid- or anaesthetic-sparing effect h. Patient-centred outcomes i. Predictability G) Adverse effects and limitations a. Cardiovascular b. Respiratory effects c. Drug interactions d. Contraindications e. Need for monitoring H) Cost and availability I) Comparison with the conventional alternative - repeat of what we saw in A) c... But in details, each point comparison J) Current evidence a. Important randomized trials b. Meta-analyses c. Regulatory approval d. Evidence in special populations e. Remaining knowledge gaps f. Place in present-day practice Does it offer a genuine clinical advantage? Which patients benefit most? Is the benefit sufficient to justify the cost? K) Concluding message Accordingly to above sub headings Give me details of 1)etomidate analogue drugs methoxy carbonyl etomidate and others 2) suzetrigine