dental plaque hypothesis nonspecific specific ecological BDS final year notes

https://periobasics.com/critical-analysis-of-various-plaque-…

mkdir -p /home/daytona/workspace/dental-plaque-ppt && ls /home/daytona/workspace…

~/dental-plaque-ppt/build.js

const pptxgen = require("pptxgenjs");
const pres = new pptxgen();
pres.layout = "LAYOUT_WIDE"; // 13.3" x 7.5"
pres.title = "Dental Plaque Hypotheses";
pres.author = "BDS Final Year";

// ─── PALETTE ───────────────────────────────────────────────────────────────
const C = {
  navy:    "0F2D4A",   // dominant dark
  teal:    "0D7377",   // accent 1
  sky:     "14A9AD",   // accent 2
  mint:    "32E0C4",   // highlight
  cream:   "F5F5F0",   // slide bg
  white:   "FFFFFF",
  gray:    "64748B",
  lgray:   "E2E8F0",
  // hypothesis colours
  h1:      "E74C3C",   // Non-specific  – red
  h2:      "2980B9",   // Specific      – blue
  h3:      "27AE60",   // Ecological    – green
  h4:      "8E44AD",   // Keystone      – purple
  h1l:     "FADBD8",
  h2l:     "D6EAF8",
  h3l:     "D5F5E3",
  h4l:     "E8DAEF",
};

// ─── HELPERS ────────────────────────────────────────────────────────────────
function titleSlide(pres, C) {
  const s = pres.addSlide();
  // full dark background
  s.background = { color: C.navy };

  // top accent bar
  s.addShape(pres.shapes.RECTANGLE, { x: 0, y: 0, w: 13.3, h: 0.18, fill: { color: C.mint }, line: { color: C.mint } });

  // big title
  s.addText("DENTAL PLAQUE\nHYPOTHESES", {
    x: 0.8, y: 1.2, w: 11.7, h: 2.4,
    fontSize: 52, bold: true, color: C.white,
    fontFace: "Calibri", align: "center", valign: "middle",
    charSpacing: 3,
  });

  // subtitle
  s.addText("A Comparative Overview for BDS Final Year", {
    x: 0.8, y: 3.5, w: 11.7, h: 0.6,
    fontSize: 20, color: C.mint, fontFace: "Calibri", align: "center",
  });

  // four coloured dots representing 4 hypotheses
  const dots = [C.h1, C.h2, C.h3, C.h4];
  const labels = ["Non-Specific", "Specific", "Ecological", "Keystone Pathogen"];
  dots.forEach((col, i) => {
    const cx = 2.5 + i * 2.2;
    s.addShape(pres.shapes.OVAL, { x: cx, y: 4.5, w: 0.35, h: 0.35, fill: { color: col }, line: { color: col } });
    s.addText(labels[i], { x: cx - 0.4, y: 4.95, w: 1.2, h: 0.3, fontSize: 9, color: C.lgray, align: "center" });
  });

  // bottom bar
  s.addShape(pres.shapes.RECTANGLE, { x: 0, y: 7.3, w: 13.3, h: 0.2, fill: { color: C.teal }, line: { color: C.teal } });
}

// Slide 2 – Overview / what is plaque
function overviewSlide(pres, C) {
  const s = pres.addSlide();
  s.background = { color: C.cream };

  // heading bar
  s.addShape(pres.shapes.RECTANGLE, { x: 0, y: 0, w: 13.3, h: 0.85, fill: { color: C.navy }, line: { color: C.navy } });
  s.addText("What is Dental Plaque?", {
    x: 0.4, y: 0, w: 12.5, h: 0.85,
    fontSize: 24, bold: true, color: C.white, valign: "middle",
  });

  // definition box
  s.addShape(pres.shapes.RECTANGLE, {
    x: 0.4, y: 1.1, w: 12.5, h: 1.15,
    fill: { color: C.navy }, line: { color: C.navy },
    shadow: { type: "outer", color: "000000", blur: 6, offset: 2, angle: 135, opacity: 0.12 },
  });
  s.addText([
    { text: "DEFINITION: ", options: { bold: true, color: C.mint } },
    { text: "An adherent deposit on the tooth surface composed almost entirely of bacteria from normal oral flora. Dental plaque is the most prevalent and densest human biofilm.", options: { color: C.white } },
  ], { x: 0.6, y: 1.15, w: 12.1, h: 1.05, fontSize: 13, valign: "middle" });

  // stages row – 4 boxes
  const stages = [
    { n: "1", title: "Pellicle\nFormation", body: "Salivary proteins coat\nthe tooth surface" },
    { n: "2", title: "Early\nColonizers", body: "Gram +ve aerobes\nStreptococci, Actinomyces\n(0-2 days)" },
    { n: "3", title: "Late\nColonizers", body: "Gram −ve anaerobes\nP. gingivalis, Treponema\n(2-4 days +)" },
    { n: "4", title: "Mature\nBiofilm", body: "Glucan polymers bind\nbiofilm; 300-400 species\nin mature plaque" },
  ];
  const cols = ["2980B9", "27AE60", "E74C3C", "8E44AD"];
  stages.forEach((st, i) => {
    const x = 0.4 + i * 3.15;
    s.addShape(pres.shapes.RECTANGLE, { x, y: 2.55, w: 3.0, h: 4.55, fill: { color: C.white }, line: { color: cols[i], pt: 2 } });
    s.addShape(pres.shapes.RECTANGLE, { x, y: 2.55, w: 3.0, h: 0.7, fill: { color: cols[i] }, line: { color: cols[i] } });
    s.addText(st.n, { x, y: 2.55, w: 0.55, h: 0.7, fontSize: 20, bold: true, color: C.white, align: "center", valign: "middle" });
    s.addText(st.title, { x: x + 0.55, y: 2.55, w: 2.45, h: 0.7, fontSize: 12, bold: true, color: C.white, valign: "middle" });
    s.addText(st.body, { x: x + 0.15, y: 3.35, w: 2.7, h: 3.55, fontSize: 11.5, color: C.navy, valign: "top" });
  });
}

// Slide 3 – Individual hypothesis cards (2x2 grid)
function fourCardsSlide(pres, C) {
  const s = pres.addSlide();
  s.background = { color: C.cream };

  s.addShape(pres.shapes.RECTANGLE, { x: 0, y: 0, w: 13.3, h: 0.85, fill: { color: C.navy }, line: { color: C.navy } });
  s.addText("The Four Plaque Hypotheses – At a Glance", {
    x: 0.4, y: 0, w: 12.5, h: 0.85, fontSize: 24, bold: true, color: C.white, valign: "middle",
  });

  const hyps = [
    {
      num: "01", name: "Non-Specific\nPlaque Hypothesis",
      year: "1930s – 1976", col: C.h1, light: C.h1l,
      icon: "⚠️",
      who: "Loesche (1976)",
      concept: "All plaque accumulation → disease\nQuantity of plaque drives severity",
      bacteria: "ALL bacteria equally responsible",
      treat: "Mechanical plaque removal\n(scaling + oral hygiene)",
      limit: "Can't explain why some with\nheavy plaque stay disease-free",
    },
    {
      num: "02", name: "Specific\nPlaque Hypothesis",
      year: "1976", col: C.h2, light: C.h2l,
      icon: "🎯",
      who: "Loesche (1976)",
      concept: "Only SELECT bacteria cause disease\nShift: Gram +ve → Gram −ve anaerobes",
      bacteria: "P. gingivalis, T. denticola\nA. actinomycetemcomitans",
      treat: "Targeted antimicrobial\ntherapy",
      limit: "Pathogens can be present\nwithout causing disease",
    },
    {
      num: "03", name: "Ecological\nPlaque Hypothesis",
      year: "1994", col: C.h3, light: C.h3l,
      icon: "🌿",
      who: "Marsh (1994)",
      concept: "Environmental changes → dysbiosis\nImbalance in microbial community",
      bacteria: "Pathogens emerge from\nexisting flora under stress",
      treat: "Restore ecological balance\n(control inflammation, pH)",
      limit: "Difficult to quantify\necological shifts precisely",
    },
    {
      num: "04", name: "Keystone Pathogen\nHypothesis",
      year: "2012", col: C.h4, light: C.h4l,
      icon: "🔑",
      who: "Hajishengallis (2012)",
      concept: "Low-abundance bacteria with\ndisproportionately LARGE impact",
      bacteria: "P. gingivalis\n(subverts innate immunity)",
      treat: "Target keystone pathogen\nto disrupt dysbiotic cascade",
      limit: "Any species can be a\nkeystone; not always predictable",
    },
  ];

  const positions = [
    { x: 0.25, y: 1.0 },
    { x: 6.9,  y: 1.0 },
    { x: 0.25, y: 4.05 },
    { x: 6.9,  y: 4.05 },
  ];

  hyps.forEach((h, i) => {
    const { x, y } = positions[i];
    const w = 6.3, cardH = 2.9;

    // card background
    s.addShape(pres.shapes.RECTANGLE, {
      x, y, w, h: cardH,
      fill: { color: C.white },
      line: { color: h.col, pt: 2 },
      shadow: { type: "outer", color: "000000", blur: 5, offset: 2, angle: 135, opacity: 0.1 },
    });

    // top colour bar
    s.addShape(pres.shapes.RECTANGLE, { x, y, w, h: 0.55, fill: { color: h.col }, line: { color: h.col } });

    // number badge
    s.addShape(pres.shapes.OVAL, { x: x + 0.1, y: y + 0.1, w: 0.38, h: 0.38, fill: { color: C.white }, line: { color: C.white } });
    s.addText(h.num, { x: x + 0.1, y: y + 0.1, w: 0.38, h: 0.38, fontSize: 9, bold: true, color: h.col, align: "center", valign: "middle" });

    // title
    s.addText(h.name, { x: x + 0.58, y, w: w - 0.7, h: 0.55, fontSize: 13, bold: true, color: C.white, valign: "middle" });

    // year chip
    s.addShape(pres.shapes.ROUNDED_RECTANGLE, { x: x + w - 1.1, y: y + 0.12, w: 0.95, h: 0.28, fill: { color: C.white }, line: { color: C.white }, rectRadius: 0.05 });
    s.addText(h.year, { x: x + w - 1.1, y: y + 0.12, w: 0.95, h: 0.28, fontSize: 7.5, color: h.col, bold: true, align: "center", valign: "middle" });

    // body rows
    const rows = [
      { label: "Concept",    val: h.concept },
      { label: "Key Bug",    val: h.bacteria },
      { label: "Treatment",  val: h.treat },
      { label: "Limitation", val: h.limit },
    ];
    rows.forEach((r, ri) => {
      const ry = y + 0.62 + ri * 0.55;
      s.addShape(pres.shapes.RECTANGLE, { x, y: ry, w: 1.3, h: 0.52, fill: { color: h.light }, line: { color: h.light } });
      s.addText(r.label.toUpperCase(), { x: x + 0.05, y: ry, w: 1.2, h: 0.52, fontSize: 8, bold: true, color: h.col, valign: "middle", align: "left" });
      s.addText(r.val, { x: x + 1.35, y: ry, w: w - 1.45, h: 0.52, fontSize: 9.5, color: C.navy, valign: "middle" });
    });
  });
}

// Slide 4 – Big comparison TABLE
function comparisonTableSlide(pres, C) {
  const s = pres.addSlide();
  s.background = { color: C.cream };

  s.addShape(pres.shapes.RECTANGLE, { x: 0, y: 0, w: 13.3, h: 0.85, fill: { color: C.navy }, line: { color: C.navy } });
  s.addText("Side-by-Side Comparison Table", {
    x: 0.4, y: 0, w: 12.5, h: 0.85, fontSize: 24, bold: true, color: C.white, valign: "middle",
  });

  const hCols = [C.h1, C.h2, C.h3, C.h4];
  const hNames = ["Non-Specific\n(1930s-1976)", "Specific\n(1976)", "Ecological\n(1994)", "Keystone Pathogen\n(2012)"];

  const rows = [
    ["Criterion", "Non-Specific\n(1930s-1976)", "Specific\n(1976)", "Ecological\n(1994)", "Keystone Pathogen\n(2012)"],
    ["Core Idea", "All plaque causes disease by bulk accumulation", "Only select bacteria cause disease", "Ecological imbalance (dysbiosis) drives disease", "Low-abundance 'keystone' bugs hijack immunity"],
    ["Key Bacteria", "All oral flora equally", "P. gingivalis, T. denticola, A. actinomycetemcomitans", "Endogenous flora shift under stress", "P. gingivalis (prototype)"],
    ["Mechanism", "Bulk acid/toxin production by total plaque mass", "Shift Gram +ve → Gram −ve anaerobes; specific virulence", "Environmental stress → overgrowth of pathogens", "Subverts complement & TLR signalling → dysbiosis"],
    ["Treatment Focus", "Mechanical removal (scaling & oral hygiene)", "Targeted antibiotics vs. specific pathogens", "Restore balance: control pH & inflammation", "Disrupt keystone to collapse dysbiotic community"],
    ["Host Role", "Minimal (not considered)", "Minimal", "Acknowledged (immune status affects ecology)", "Central – immune disruption is the key event"],
    ["Strength", "Simple; explains gingivitis with plaque accumulation", "Explains site-specific & aggressive disease", "Explains why pathogens present without disease", "Explains low-abundance impact; modern dysbiosis model"],
    ["Limitation", "Ignores host variation & microbial specificity", "Pathogens present in healthy mouths too", "Hard to quantify ecological triggers", "Any species can be a keystone; not always predictable"],
    ["Current Status", "Largely abandoned", "Partially accepted", "Widely accepted – foundation of modern periodontology", "Most current; under active research"],
  ];

  // column widths: criterion col wider
  const colW = [2.3, 2.65, 2.65, 2.65, 2.65];

  const tableData = rows.map((row, ri) => {
    return row.map((cell, ci) => {
      // header row
      if (ri === 0) {
        if (ci === 0) return { text: cell, options: { fill: { color: C.navy }, color: C.white, bold: true, fontSize: 11, align: "center", valign: "middle" } };
        return { text: cell, options: { fill: { color: hCols[ci - 1] }, color: C.white, bold: true, fontSize: 10, align: "center", valign: "middle" } };
      }
      // criterion column
      if (ci === 0) return { text: cell, options: { fill: { color: C.navy }, color: C.mint, bold: true, fontSize: 9.5, align: "left", valign: "middle" } };
      // alternating row shading
      const lightCols = [C.h1l, C.h2l, C.h3l, C.h4l];
      const bg = ri % 2 === 0 ? lightCols[ci - 1] : C.white;
      return { text: cell, options: { fill: { color: bg }, color: C.navy, fontSize: 9, align: "left", valign: "middle" } };
    });
  });

  s.addTable(tableData, {
    x: 0.15, y: 1.0, w: 12.95,
    colW: colW,
    rowH: 0.64,
    border: { pt: 1, color: C.lgray },
    autoPage: false,
  });
}

// Slide 5 – Evolution timeline
function timelineSlide(pres, C) {
  const s = pres.addSlide();
  s.background = { color: C.navy };

  s.addShape(pres.shapes.RECTANGLE, { x: 0, y: 0, w: 13.3, h: 0.85, fill: { color: C.teal }, line: { color: C.teal } });
  s.addText("Evolution of Plaque Hypotheses – Timeline", {
    x: 0.4, y: 0, w: 12.5, h: 0.85, fontSize: 24, bold: true, color: C.white, valign: "middle",
  });

  // horizontal timeline bar
  s.addShape(pres.shapes.RECTANGLE, { x: 0.8, y: 3.4, w: 11.7, h: 0.1, fill: { color: C.mint }, line: { color: C.mint } });

  const events = [
    { x: 1.0,  year: "1930s", label: "Non-Specific\nPlaque Hypothesis", col: C.h1, desc: "All plaque =\nbad plaque" },
    { x: 4.1,  year: "1976",  label: "Specific\nPlaque Hypothesis",     col: C.h2, desc: "Select bacteria\ncause disease" },
    { x: 7.2,  year: "1994",  label: "Ecological\nPlaque Hypothesis",   col: C.h3, desc: "Dysbiosis /\nbalance shift" },
    { x: 10.3, year: "2012",  label: "Keystone Pathogen\nHypothesis",   col: C.h4, desc: "P. gingivalis\nhijacks immunity" },
  ];

  events.forEach((ev, i) => {
    // vertical stem
    s.addShape(pres.shapes.RECTANGLE, { x: ev.x + 0.55, y: i % 2 === 0 ? 2.1 : 3.5, w: 0.04, h: i % 2 === 0 ? 1.3 : 1.3, fill: { color: ev.col }, line: { color: ev.col } });

    // dot on line
    s.addShape(pres.shapes.OVAL, { x: ev.x + 0.38, y: 3.24, w: 0.38, h: 0.38, fill: { color: ev.col }, line: { color: C.white, pt: 2 } });

    // year
    s.addText(ev.year, { x: ev.x, y: 3.62, w: 1.2, h: 0.35, fontSize: 13, bold: true, color: ev.col, align: "center" });

    // card
    const cardY = i % 2 === 0 ? 1.1 : 4.05;
    s.addShape(pres.shapes.RECTANGLE, {
      x: ev.x - 0.1, y: cardY, w: 2.5, h: 1.6,
      fill: { color: "1A3A5C" }, line: { color: ev.col, pt: 2 },
    });
    s.addShape(pres.shapes.RECTANGLE, { x: ev.x - 0.1, y: cardY, w: 2.5, h: 0.42, fill: { color: ev.col }, line: { color: ev.col } });
    s.addText(ev.label, { x: ev.x - 0.05, y: cardY, w: 2.4, h: 0.42, fontSize: 9.5, bold: true, color: C.white, valign: "middle", align: "center" });
    s.addText(ev.desc, { x: ev.x - 0.05, y: cardY + 0.47, w: 2.4, h: 1.08, fontSize: 11, color: C.lgray, valign: "top", align: "center" });
  });

  // arrow at end of line
  s.addShape(pres.shapes.RIGHT_ARROW, { x: 12.4, y: 3.28, w: 0.6, h: 0.28, fill: { color: C.mint }, line: { color: C.mint } });
  s.addText("Present", { x: 12.2, y: 3.62, w: 1.0, h: 0.35, fontSize: 11, color: C.mint, align: "center" });

  // footnote
  s.addText("Each hypothesis built on — and refined — the previous one. Modern periodontology uses the Ecological + Keystone Pathogen frameworks.", {
    x: 0.5, y: 7.0, w: 12.3, h: 0.38, fontSize: 10, color: C.lgray, align: "center", italic: true,
  });
}

// Slide 6 – Socransky's Complexes
function socranskySlide(pres, C) {
  const s = pres.addSlide();
  s.background = { color: C.cream };

  s.addShape(pres.shapes.RECTANGLE, { x: 0, y: 0, w: 13.3, h: 0.85, fill: { color: C.navy }, line: { color: C.navy } });
  s.addText("Socransky's Microbial Complexes (1998) – Related Concept", {
    x: 0.4, y: 0, w: 12.5, h: 0.85, fontSize: 22, bold: true, color: C.white, valign: "middle",
  });

  s.addText("Socransky classified subgingival bacteria into colour-coded complexes based on disease association:", {
    x: 0.5, y: 1.0, w: 12.3, h: 0.5, fontSize: 13, color: C.navy,
  });

  const complexes = [
    { col: "C0392B", name: "RED Complex", label: "Strongly Disease-Associated", bugs: ["Porphyromonas gingivalis", "Treponema denticola", "Tannerella forsythia"], note: "Always present in deep pockets and active disease" },
    { col: "E67E22", name: "ORANGE Complex", label: "Bridge – Early to Late Colonizers", bugs: ["Fusobacterium nucleatum", "Prevotella intermedia", "Peptostreptococcus micros"], note: "Paves the way for Red complex organisms" },
    { col: "F1C40F", name: "YELLOW Complex", label: "Health-Associated (Early)", bugs: ["Streptococcus sanguis", "S. mitis", "S. gordonii"], note: "Predominant in health; inhibit pathogens" },
    { col: "27AE60", name: "GREEN Complex", label: "Early Colonizers", bugs: ["Capnocytophaga spp.", "Aggregatibacter aphrophilus", "Eikenella corrodens"], note: "Attach to pellicle; co-aggregate with early streptococci" },
    { col: "2980B9", name: "PURPLE Complex", label: "Early Colonizers", bugs: ["Veillonella parvula", "Actinomyces odontolyticus"], note: "Found in both health and disease" },
  ];

  complexes.forEach((cx, i) => {
    const x = 0.3 + i * 2.55;
    s.addShape(pres.shapes.RECTANGLE, {
      x, y: 1.65, w: 2.4, h: 5.4,
      fill: { color: C.white }, line: { color: cx.col, pt: 2 },
    });
    s.addShape(pres.shapes.RECTANGLE, { x, y: 1.65, w: 2.4, h: 0.75, fill: { color: cx.col }, line: { color: cx.col } });
    s.addText(cx.name, { x, y: 1.65, w: 2.4, h: 0.45, fontSize: 11, bold: true, color: C.white, align: "center", valign: "middle" });
    s.addText(cx.label, { x, y: 2.1, w: 2.4, h: 0.3, fontSize: 7.5, color: C.white, align: "center", italic: true });

    // bacteria list
    cx.bugs.forEach((b, bi) => {
      s.addText("• " + b, { x: x + 0.1, y: 2.5 + bi * 0.55, w: 2.2, h: 0.5, fontSize: 9.5, color: C.navy, italic: true });
    });

    // note
    s.addShape(pres.shapes.RECTANGLE, { x, y: 6.15, w: 2.4, h: 0.9, fill: { color: cx.col + "22" }, line: { color: cx.col } });
    s.addText(cx.note, { x: x + 0.1, y: 6.2, w: 2.2, h: 0.8, fontSize: 8.5, color: C.navy, italic: true, valign: "middle" });
  });
}

// Slide 7 – Exam Quick Recall
function examSlide(pres, C) {
  const s = pres.addSlide();
  s.background = { color: C.navy };

  s.addShape(pres.shapes.RECTANGLE, { x: 0, y: 0, w: 13.3, h: 0.85, fill: { color: C.h4 }, line: { color: C.h4 } });
  s.addText("⚡  Quick Recall – Exam Tips", {
    x: 0.4, y: 0, w: 12.5, h: 0.85, fontSize: 24, bold: true, color: C.white, valign: "middle",
  });

  // 5-mark answer guide
  s.addShape(pres.shapes.RECTANGLE, {
    x: 0.3, y: 1.0, w: 5.9, h: 6.0,
    fill: { color: "1A3A5C" }, line: { color: C.mint, pt: 2 },
  });
  s.addShape(pres.shapes.RECTANGLE, { x: 0.3, y: 1.0, w: 5.9, h: 0.5, fill: { color: C.mint }, line: { color: C.mint } });
  s.addText("5-MARK ANSWER STRUCTURE", { x: 0.35, y: 1.0, w: 5.8, h: 0.5, fontSize: 12, bold: true, color: C.navy, valign: "middle", align: "center" });

  const marks = [
    "1 mark  →  Define dental plaque + biofilm stages",
    "1 mark  →  Non-specific hypothesis + limitation",
    "1 mark  →  Specific hypothesis + key bacteria (Red Complex)",
    "1 mark  →  Ecological hypothesis (Marsh 1994) + dysbiosis",
    "1 mark  →  Keystone pathogen hypothesis (P. gingivalis)",
  ];
  marks.forEach((m, i) => {
    s.addShape(pres.shapes.RECTANGLE, { x: 0.38, y: 1.6 + i * 0.82, w: 0.45, h: 0.45, fill: { color: C.mint }, line: { color: C.mint } });
    s.addText(String(i + 1), { x: 0.38, y: 1.6 + i * 0.82, w: 0.45, h: 0.45, fontSize: 14, bold: true, color: C.navy, align: "center", valign: "middle" });
    s.addText(m, { x: 0.9, y: 1.6 + i * 0.82, w: 5.1, h: 0.45, fontSize: 10.5, color: C.lgray, valign: "middle" });
  });

  // mnemonics box
  s.addShape(pres.shapes.RECTANGLE, {
    x: 6.5, y: 1.0, w: 6.5, h: 6.0,
    fill: { color: "1A3A5C" }, line: { color: C.h1, pt: 2 },
  });
  s.addShape(pres.shapes.RECTANGLE, { x: 6.5, y: 1.0, w: 6.5, h: 0.5, fill: { color: C.h1 }, line: { color: C.h1 } });
  s.addText("MNEMONICS & KEY FACTS", { x: 6.55, y: 1.0, w: 6.4, h: 0.5, fontSize: 12, bold: true, color: C.white, valign: "middle", align: "center" });

  const mnemos = [
    { q: "Non-Specific", a: "\"All plaque is BAD plaque\" – no bacterial specificity" },
    { q: "Specific", a: "RED COMPLEX: P. gingivalis, T. denticola, T. forsythia" },
    { q: "Ecological", a: "MARSH 1994 – dysbiosis key word; ecological stress = disease" },
    { q: "Keystone", a: "HAJISHENGALLIS 2012 – P. gingivalis in low numbers → big damage" },
    { q: "Socransky", a: "Red > Orange > Yellow > Green > Purple (disease → health)" },
    { q: "Treatment", a: "NSH → scaling | SPH → antibiotics | EcoPH → restore balance" },
  ];
  mnemos.forEach((mn, i) => {
    const my = 1.65 + i * 0.82;
    s.addShape(pres.shapes.RECTANGLE, { x: 6.55, y: my, w: 2.0, h: 0.45, fill: { color: C.h1 + "55" }, line: { color: C.h1 } });
    s.addText(mn.q, { x: 6.6, y: my, w: 1.9, h: 0.45, fontSize: 9, bold: true, color: C.white, valign: "middle" });
    s.addText(mn.a, { x: 8.6, y: my, w: 4.2, h: 0.45, fontSize: 9.5, color: C.lgray, valign: "middle" });
  });
}

// ─── BUILD ──────────────────────────────────────────────────────────────────
titleSlide(pres, C);
overviewSlide(pres, C);
fourCardsSlide(pres, C);
comparisonTableSlide(pres, C);
timelineSlide(pres, C);
socranskySlide(pres, C);
examSlide(pres, C);

pres.writeFile({ fileName: "/home/daytona/workspace/dental-plaque-ppt/Dental_Plaque_Hypotheses.pptx" })
  .then(() => console.log("PPT created successfully"))
  .catch(err => console.error("Error:", err));

cd /home/daytona/workspace/dental-plaque-ppt && node build.js

~/dental-plaque-ppt/build.js

Successfully replaced 1 instance(s) of the string in '/home/daytona/workspace/dental-plaque-ppt/build.js'

~/dental-plaque-ppt/build.js

Successfully replaced 1 instance(s) of the string in '/home/daytona/workspace/dental-plaque-ppt/build.js'

cd /home/daytona/workspace/dental-plaque-ppt && node build.js 2>&1