You are answering a USMLE-style medical question. Question: A 49-year-old woman is brought to the emergency department with progressive dyspnea and cough which she developed approx. 8 hours ago. 2 weeks ago she had a prophylactic ovariectomy because of a family history of ovarian cancer. She is known to have type 2 diabetes mellitus and stage 1 hypertension, but she does not take her antihypertensives because she is not concerned about her blood pressure. Also, she has a history of opioid abuse. She takes metformin 1000 mg and aspirin 81 mg. She has been smoking 1 pack of cigarettes per day for 22 years. Her vital signs are as follows: blood pressure 155/80 mm Hg, heart rate 101/min, respiratory rate 31/min, and temperature 37.9℃ (100.2℉). Blood saturation on room air is 89%. On examination, the patient is dyspneic and acrocyanotic. Lung auscultation reveals bilateral rales over the lower lobes. A cardiac examination is significant for S2 accentuation best heard in the second intercostal space at the left sternal border and S3 presence. There is no leg edema. Neurological examination is within normal limits. Arterial blood gases analysis shows the following results: pH 7.49 PaO2 58 mm Hg PaCO2 30 mm Hg HCO3- 22 mEq/L Based on the given data, which of the following could cause respiratory failure in this patient? Options: A) Increased alveolar dead space due to absent perfusion of certain alveoli B) Alveolar fibrosis C) Depression of the respiratory center via opioid receptors activation D) Decreased V/Q due to bronchial obstruction Reply with ONLY the letter of the correct answer (A, B, C, or D). No explanation.