A total of 35 Whipple specimens were analysed over the last 5.5 years. Out of the 36 specimens, 20 were periampullary tumor, 11 were ampullary and 4 involved both mixed site. Amongst the periampullary tumors, the most common histological diagnosis was adenocarcinoma, pancreatobiliary type. The most common diagnosis in ampullary tumors was adenocarcinoma, pancreatobilary followed by intestinal types. The most common precursor lesions encountered were- adenoma, tubulovillous and intestital type, high grade dysplasia and intra-ampullary papillary neoplasm. Apart from adenocarcinoma, 2 case each of signet ring cell carcinoma and adenosquamous carcinoma were identified. Refine the above text into scientic paragraph
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Over the past 5.5 years, a total of 35 Whipple resection specimens were analysed. Of these, 20 cases were periampullary tumours, 11 were ampullary tumours, and 4 involved mixed sites. Among periampullary tumours, adenocarcinoma of pancreatobiliary type was the most frequent histological diagnosis. Similarly, ampullary tumours most commonly comprised pancreatobiliary-type adenocarcinoma, followed by intestinal-type adenocarcinoma. The most frequently encountered precursor lesions included tubulovillous adenoma of intestinal type with high-grade dysplasia and intra-ampullary papillary neoplasm. In addition to conventional adenocarcinoma, two cases each of signet-ring cell carcinoma and adenosquamous carcinoma were identified.
Note: The original text states both 35 and 36 specimens. This version uses 35; please verify the total before submission.
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