Diffrent types of oxygen therapy - give table

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Types of Oxygen Therapy

Based on Roberts and Hedges' Clinical Procedures in Emergency Medicine and Rosen's Emergency Medicine.

Low-Flow Devices (Variable FiO₂)

These deliver O₂ at a flow less than the patient's inspiratory flow rate; room air is entrained to make up the difference, so FiO₂ varies with the patient's breathing pattern.
DeviceFlow RateFiO₂ DeliveredKey Features / Notes
Nasal Cannula1-6 L/min~24-44%Comfortable, well-tolerated; FiO₂ rises ~4% per L/min; nasopharynx acts as reservoir; fire risk if patient smokes
Simple Face Mask5-10 L/min~35-55% (up to 80-90% at 30 L/min)Mask volume (~200 mL) acts as reservoir; vent holes allow room air entrainment; min 5 L/min to flush CO₂
Partial Non-Rebreather Mask6-15 L/min~50-70%Reservoir bag adds oxygen reserve; no one-way valves; some exhaled gas re-enters bag
Non-Rebreather Mask (NRM)10-15 L/min (standard); up to 45+ L/min~70% at 15 L/min; ~90%+ at 45 L/minOne-way valves prevent exhaled gas entering reservoir + room air entering mask; commonly misunderstood to deliver near 100% - in practice ~70% at standard settings

High-Flow / Fixed FiO₂ Devices

These deliver total gas flow that meets or exceeds the patient's inspiratory demand, minimizing room air entrainment and providing more consistent FiO₂.
DeviceFlow RateFiO₂ DeliveredKey Features / Notes
Venturi Mask (Air-Entrainment Mask)2-15 L/min O₂ source (total gas flow ~30 L/min)24%, 28%, 31%, 35%, 40%, 60% (color-coded jets)Precise, titratable FiO₂; preferred in COPD patients; cannot reliably exceed 35% FiO₂; FiO₂ drops in respiratory distress if inspiratory flow >30 L/min
High-Flow Nasal Cannula (HFNC)5-60 L/min (heated, humidified)70-80% at 15 L/min; ~90%+ at 45 L/min; up to ~100%Wide-bore nasal prongs; requires humidifier; provides ~5 cmH₂O PEEP effect; better tolerated than face mask/NPPV; suitable for hypoxemic respiratory failure

Positive Pressure / Ventilatory Support Devices

DeviceFiO₂Key Features / Notes
Non-Invasive Positive Pressure Ventilation (NPPV/NIV) - includes CPAP & BiPAP21-100% (titrated)Tight-fitting mask; delivers set pressures; used in COPD exacerbation, pulmonary edema, OSA; avoids intubation
Bag-Valve-Mask (BVM / Ambu bag)~40-60% without O₂ reservoir; ~90-100% with reservoir + 15 L/min O₂Manual ventilation for apneic patients; rescue device after failed intubation; tidal volume ~500 mL over 1-1.5 sec to minimize gastric inflation
Invasive Mechanical Ventilation (Endotracheal Tube / ETT)21-100% (precisely set)Full control of FiO₂, PEEP, tidal volume, rate; used for respiratory failure, airway protection, apnea; gold standard for most critical patients

Hyperbaric / Specialized Devices

DeviceFiO₂ / PressureKey Features / Notes
Hyperbaric Oxygen Chamber100% O₂ at >1 atm (2-3 ATA)Used for CO poisoning, decompression sickness, gas gangrene, wound healing; CO half-life cut from ~4-5 hr (room air) to ~20 min
Portable Hyperbaric Chamber (Gamow bag)Simulates descent by pressurizationUsed in wilderness/altitude medicine for high-altitude illness when descent is impossible
Transtracheal Oxygen (TTO)Low flow (0.5-2 L/min)Catheter inserted percutaneously into trachea; used for long-term home O₂; more efficient than nasal cannula, cosmetically preferred

Quick Reference: FiO₂ by Device

DeviceMin FiO₂Max FiO₂
Nasal cannula~24%~44%
Simple mask~35%~90% (high flow)
Non-rebreather mask~60%~90% (high flow)
Venturi mask24%~60% (but unreliable >35%)
HFNC~30%~100%
NPPV/NIV21%100%
Mechanical ventilation21%100%
Hyperbaric chamber100%100% at elevated pressure

Key clinical points:
  • Never withhold O₂ from a hypoxemic patient out of fear of complications; CO₂ retention is a reason for caution, not a contraindication
  • Target SpO₂ 94-98% in most patients; 88-92% in COPD (to avoid blunting hypoxic drive)
  • In STEMI, O₂ is only indicated if SpO₂ <90%; routine O₂ in normoxic MI patients increases infarct size
  • At 100% FiO₂, CO-poisoning carboxyhemoglobin half-life drops from ~5 hours to ~1 hour
Sources: Roberts and Hedges' Clinical Procedures in Emergency Medicine; Rosen's Emergency Medicine, 10e

High flow , low flow

Here is a focused comparison of High-Flow vs Low-Flow Oxygen Systems:

Low-Flow vs High-Flow Oxygen Systems

The key distinction is not the liter-per-minute rate but whether the device meets the patient's total inspiratory demand.

Core Concept

ParameterLow-Flow SystemHigh-Flow System
DefinitionO₂ flow is LESS than patient's inspiratory flow rateO₂ flow MEETS or EXCEEDS patient's inspiratory flow rate
Room air entrainmentYES - variable amount entrained to make up the deficitMINIMAL to NONE
FiO₂Variable - changes with patient's breathing patternFixed / predictable
Effect of tachypnoeaFiO₂ drops as respiratory rate/depth increasesFiO₂ remains stable
Patient's inspiratory flowTypically 30-100 L/min in distressDevice matches or exceeds this

Low-Flow Devices

DeviceO₂ Flow (L/min)Approx FiO₂Notes
Nasal Cannula1~24%+4% per extra L/min (rough rule)
2~28%
3~32%
4~36%
5~40%
6~44%Max for standard nasal cannula
Simple Face Mask5-6~35-40%Min 5 L/min to wash out CO₂
8-10~45-55%
Partial Rebreather Mask6-10~40-70%Reservoir bag, no one-way valves
Non-Rebreather Mask10-15~60-80%One-way valves; commonly thought to give 100% but actually ~70% at 15 L/min
Limitation: In a distressed, tachypnoeic patient, all low-flow devices deliver LESS FiO₂ than predicted because more room air is entrained.

High-Flow Devices

DeviceO₂ Flow (L/min)FiO₂Notes
Venturi Mask224%Color-coded jets (blue = 24%)
428%White jet
631%Yellow jet
835%Red jet
1040%Green jet
1560%Pink jet (unreliable >35% in distress)
High-Flow Nasal Cannula (HFNC)15~70-80%Heated, humidified; wide-bore prongs
30-40~90%
40-60~95-100%Provides ~5 cmH₂O PEEP effect
NRM at flush flow40-45+~90%+Standard flowmeter opened to flush

Side-by-Side Summary

FeatureLow-FlowHigh-Flow
ExamplesNasal cannula, simple mask, NRM (standard)Venturi mask, HFNC, NRM at flush
FiO₂ precisionPoor - variableGood - predictable
FiO₂ range24-80%24-100%
Affected by breathing pattern?YESMinimally (Venturi) / No (HFNC at high flows)
Humidification needed?Not usually (up to 4 L/min nasal cannula)YES for HFNC (nearly 100% humidity required)
PEEP effectNoneSmall (~3-5 cmH₂O with HFNC)
Equipment complexitySimple, cheapMore complex (HFNC needs special setup)
Patient comfortHigh (cannula) / Moderate (mask)High (HFNC) / Moderate (Venturi mask)
Best forMild-moderate hypoxia, stable breathingSevere hypoxia, respiratory distress, COPD (Venturi)
Use in COPDRisky without titrationVenturi preferred (precise low FiO₂)

Clinical Decision Guide

SpO₂ < 90%, stable breathing → Nasal cannula 2-4 L/min (low-flow)
SpO₂ < 90%, COPD → Venturi mask 24-28% (high-flow, controlled)
Moderate hypoxia, distress → Simple mask / NRM 10-15 L/min
Severe hypoxia, avoid intubation → HFNC 30-60 L/min
CO poisoning → NRM at flush / 100% O₂
Apnoea / arrest → BVM + 100% O₂ → Intubation

Key rule to remember: A Venturi mask running at only 2 L/min source O₂ is classified as high-flow because its total delivered gas (O₂ + entrained air) = ~30 L/min, matching the patient's inspiratory demand. A non-rebreather at 15 L/min is technically low-flow because 15 L/min still falls short of a distressed patient's 50-100 L/min inspiratory demand.
Source: Roberts and Hedges' Clinical Procedures in Emergency Medicine
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