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paediatric clinic anthropometry weight height head circumference BMI techniques child examination

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Paediatric Clinic: Anthropometry and Clinical Examination

A comprehensive guide covering measurements, techniques, interpretation, and the full systematic examination of children in clinic.

PART 1 - ANTHROPOMETRY

Anthropometry is the science of measuring the human body. In paediatrics, it forms the backbone of assessing growth, nutritional status, and development. As Park's Textbook of Preventive and Social Medicine states: "Anthropometric measurements such as height, weight, skinfold thickness and arm circumference are valuable indicators of nutritional status. In young children, additional measurements such as head and chest circumference are made. If recorded over time, they reflect patterns of growth and development and how individuals deviate from the average."

1.1 Core Anthropometric Parameters

MeasurementAge GroupToolNormal Reference
WeightAll agesCalibrated beam/digital scaleWHO Growth Charts
Length (supine)0-2 yearsInfantometer / length boardWHO 0-2 yr charts
Height (standing)>2 yearsStadiometerWHO/CDC 2-18 yr charts
Head circumference (OFC)0-2 years (up to 3 yrs)Non-stretch measuring tapeWHO charts
Mid-upper arm circumference (MUAC)6 months - 5 yearsMUAC tape (tri-colour)<11.5 cm = SAM; 11.5-12.5 = MAM
Chest circumference0-5 yearsMeasuring tapeCC > HC after 6 months = normal
Skinfold thicknessOlder childrenHarpenden callipersTriceps, subscapular
BMI (wt/ht²)2-18 yearsCalculatedz-scores or percentiles
Waist circumference>2 yearsTapeMetabolic risk screen

1.2 How to Measure - Techniques

Weight

  • Infants (<2 years): Use a pan/beam scale. Remove all clothing and nappies. Weigh to the nearest 10 g.
  • Children (>2 years): Stand on upright digital scale. Minimal clothing, no shoes. Weigh to nearest 100 g.
  • Trick: Weigh mother holding baby, subtract mother's weight if infant is uncooperative.

Length (0-2 years)

  • Use an infantometer (length board with fixed headplate and movable footplate).
  • Child lies supine. One observer holds the head with the Frankfurt plane vertical (eyes looking straight up). Second observer extends the knees, keeps feet flat at 90°, and reads the footplate.
  • Measure to the nearest 0.1 cm.
  • Children measured lying are approximately 0.7 cm longer than standing - remember this at the 2-year handover.

Height (>2 years)

  • Use a stadiometer fixed to a flat wall (no skirting board).
  • Child stands barefoot, feet together, heels/buttocks/shoulder blades/back of head touching the wall (not all four are always possible - heels and head are priorities).
  • Frankfurt plane horizontal (bottom of eye socket level with the top of the ear canal, eyes looking straight ahead).
  • Deep breath in, read at maximum inspiration with the headpiece pressed firmly.
  • Measure to nearest 0.1 cm, best in the morning (diurnal variation: children are ~1 cm shorter in the afternoon due to spinal compression).

Head Circumference (OFC - Occipito-Frontal Circumference)

  • Use a non-stretch tape (paper or fibreglass, never cloth).
  • Measure the maximum circumference: tape passes over the most prominent part of the occiput posteriorly and the glabella (supraorbital ridges) anteriorly.
  • Take the largest of 3 readings.
  • Key values (approximate):
    • Birth: ~34 cm
    • 3 months: ~40 cm
    • 6 months: ~43 cm
    • 1 year: ~46-47 cm
    • 2 years: ~49 cm
    • Adult: ~54-57 cm
  • Growth rate: ~2 cm/month in months 1-3; ~1 cm/month months 4-6; ~0.5 cm/month months 7-12.

MUAC (Mid-Upper Arm Circumference)

  • Locate the midpoint between the acromion and the tip of the olecranon with the arm bent at 90°. Mark with a pen.
  • Let the arm hang relaxed at the side. Place the tape around the mid-arm, ensuring it is horizontal and snug but not compressing tissue.
  • Interpretation (WHO, 6 months - 5 years):
    • ≥12.5 cm: Normal
    • 11.5 - <12.5 cm: Moderate acute malnutrition (MAM)
    • <11.5 cm: Severe acute malnutrition (SAM)
  • MUAC is preferred over weight-for-height in field settings because it does not require age verification.

Chest Circumference

  • Measured at the level of the nipples during mid-respiration.
  • At birth: CC ≈ HC (both ~32-34 cm). After 6 months, CC exceeds HC = normal. If HC > CC persists beyond 6 months = consider macrocephaly or undernutrition.

Skinfold Thickness

  • Triceps skinfold: Posterior midline of the upper arm at the marked midpoint. Grasp a vertical fold of skin and subcutaneous fat, apply Harpenden callipers, read after 2 seconds.
  • Subscapular skinfold: Just below the inferior angle of the scapula at 45°.
  • Together these estimate percentage body fat.

1.3 Indices and Derived Measurements

BMI (Body Mass Index)

  • Formula: Weight (kg) / Height² (m²)
  • In children, BMI is age- and sex-specific; use z-scores or percentiles (not adult cut-offs).
  • WHO thresholds for children 5-19 years:
    • <-2 SD: Thinness
    • <-3 SD: Severe thinness
    • +1 SD: Overweight
    • +2 SD: Obese

Weight-for-Age (WFA)

  • Reflects overall growth, but cannot distinguish between stunting and wasting.
  • <-2 SD = Underweight; <-3 SD = Severe underweight.

Height/Length-for-Age (HFA/LFA)

  • Reflects chronic malnutrition / stunting.
  • <-2 SD = Stunted; <-3 SD = Severely stunted.

Weight-for-Height (WFH) / Weight-for-Length (WFL)

  • Reflects acute malnutrition / wasting. Independent of age.
  • <-2 SD = Wasted (acute malnutrition); <-3 SD = Severely wasted.

Interpretation Summary (WHO Classification)

ConditionIndexCut-off
StuntingHeight-for-age<-2 SD
WastingWeight-for-height<-2 SD
UnderweightWeight-for-age<-2 SD
OverweightBMI-for-age>+1 SD (5-19 yrs) or WFH >+2 SD (<5 yrs)
ObesityBMI-for-age>+2 SD

1.4 Growth Charts

  • WHO Growth Standards (0-5 years): Based on healthy, breastfed children from 6 countries. Prescriptive (how children should grow).
  • WHO Growth Reference (5-19 years): Descriptive (how children do grow in population sample).
  • CDC Charts (2000): Alternative reference; used primarily in the USA.
  • UK-WHO 0-4 Charts (RCPCH): Hybrid charts used in the UK.
How to plot:
  1. Identify child's age (correct for prematurity until 2 years for <32 weeks, until 1 year for 32-36 weeks).
  2. Find the intersection of age (x-axis) and measurement (y-axis).
  3. Identify which centile/SD line the point falls on.
  4. Concern if crossing 2+ centile lines downward, or consistently below -2 SD.

PART 2 - CLINICAL EXAMINATION IN PAEDIATRICS

2.1 The Paediatric Consultation: General Principles

  • History first - children cannot fully articulate; parents are key informants.
  • Observe before touching. A child playing happily in the waiting room is not critically ill.
  • Build rapport - talk to the child at eye level, use their name, offer a toy, let them see and touch equipment.
  • Opportunistic examination - examine what you can when the child cooperates; don't follow rigid head-to-toe order in toddlers.
  • Respect modesty in older children.
  • Parental presence is usually reassuring for younger children; for adolescents, offer time alone for sensitive questions.

2.2 The Approach by Age

Age GroupKey Approach
Neonate (0-28 days)Full undressed examination; parent holds initially
Infant (1-12 months)Examine on parent's lap; cardiac/respiratory while quiet
Toddler (1-3 years)Most difficult - use distraction, games, toys
Pre-school (3-5 years)Can follow simple instructions; "show me where it hurts"
School-age (5-12 years)Systematic exam; explain what you are doing
Adolescent (>12 years)Privacy, confidentiality; consider HEADS screening

2.3 General Inspection (The Global Assessment)

Before laying hands, observe:
  • Colour: Pink (normal), pale (anaemia), cyanosis (central vs peripheral), jaundice, mottled (poor perfusion), plethoric.
  • Breathing: Tachypnoea, recession (subcostal, intercostal, sternal), head-bobbing in infants, nasal flaring, stridor, grunting, wheeze.
  • Conscious state: Alert, irritable, lethargic, AVPU scale.
  • Tone: Hypotonic ("floppy") vs hypertonic.
  • Dysmorphic features: Syndromes (Down's, Turner's, Marfan's, etc.)
  • Nutritional state: Wasting, oedema (kwashiorkor), pot belly.
  • Skin: Rashes, bruising, marks, pallor, eczema.
Traffic Light System (NICE) for acutely ill child:
  • Green = Low risk; Amber = Intermediate risk; Red = High risk.

2.4 Vital Signs - Paediatric Normal Values

AgeRR (breaths/min)HR (beats/min)SBP (mmHg)
Neonate40-60100-16060-90
Infant (1-12 mo)30-40100-16070-100
Toddler (1-3 yr)25-3590-15080-110
Pre-school (3-5 yr)25-3080-14080-110
School-age (5-12 yr)20-2570-12090-120
Adolescent (>12 yr)15-2060-100100-130
  • Tachycardia is the most sensitive early indicator of shock in children.
  • Hypotension is a late sign of decompensated shock - paediatric patients maintain BP until 25-30% blood loss.
Temperature:
  • Normal: 36.5 - 37.5°C (axillary or tympanic).
  • Fever: ≥38.0°C rectal; ≥37.5°C axillary.
  • In infants <3 months: any fever ≥38°C = serious until proven otherwise.
Oxygen saturation:
  • SpO₂ >95% is normal in most children.
  • 92-94%: supplemental oxygen needed; <92%: urgent management.
Blood pressure:
  • Use the correct cuff size: cuff width = 40% of upper arm circumference.
  • Normal lower limit of SBP = 70 + (2 × age in years) for 1-10 years.

2.5 Systematic Examination

A. Cardiovascular

Inspection:
  • Central cyanosis (tongue, mucous membranes)
  • Peripheral oedema
  • Visible precordial pulsation
  • Clubbing (chronic hypoxia, SBE, cyanotic CHD)
  • Scars (previous cardiac surgery - midline sternotomy, lateral thoracotomy)
Palpation:
  • Apex beat: 4th intercostal space, midclavicular line in <7 years; 5th space in >7 years.
  • Heaves (right or left ventricular), thrills.
  • Femoral pulses: always palpate both simultaneously to exclude coarctation of the aorta (radio-femoral delay or absence).
  • Liver: right heart failure causes hepatomegaly in children (not peripheral oedema as in adults).
Auscultation:
  • Innocent murmurs are common in children (present in up to 50%):
    • Still's murmur: musical, vibratory, 2/6, lower left sternal edge, disappears when supine.
    • Venous hum: continuous, infraclavicular, disappears with head turning/Valsalva.
    • Pulmonary flow murmur: systolic, upper left sternal edge.
  • Pathological murmur features: harsh, pansystolic, diastolic, grade ≥3, associated thrill, radiates, no change with position, associated symptoms.

B. Respiratory

Inspection:
  • Respiratory rate (count for full 60 seconds in young infants)
  • Chest shape: hyperinflation (barrel chest = chronic air trapping as in asthma), pectus excavatum, pectus carinatum, Harrison's sulcus (chronic subcostal recession leaving a groove = long-standing airways disease)
  • Work of breathing: subcostal, intercostal, supraclavicular recession; nasal flaring; tracheal tug; head bobbing (infants)
  • Breathing pattern: abdominal breathing is normal in infants
Grunting = infant closing glottis to maintain end-expiratory pressure = severe respiratory distress, lower airway disease.
Palpation: Tracheal position, chest expansion.
Percussion: Less reliable than in adults in young children; resonant / dull / stony dull / hyperresonant.
Auscultation:
  • Crackles: fine (pulmonary oedema, pneumonia), coarse (secretions, bronchiectasis)
  • Wheeze: expiratory or biphasic (obstructive)
  • Stridor: inspiratory = extrathoracic obstruction (croup, epiglottitis, inhaled foreign body); expiratory stridor = intrathoracic
  • Bronchial breathing: consolidation

C. Gastrointestinal / Abdomen

Inspection:
  • Abdominal distension: gaseous (obstruction), ascitic (liver disease, nephrotic syndrome), organomegaly.
  • Visible peristalsis: pyloric stenosis (waves from left to right in epigastrium)
  • Umbilicus: hernias are common and usually resolve by age 4-5 years.
  • Scars, skin changes.
Auscultation before palpation (standard in abdominal examination).
Palpation:
  • Begin away from the area of pain; use warm hands, distract with conversation.
  • Liver: Palpate from the RIF upward. Normal in infants up to 2 cm BCM. Note span by percussion.
  • Spleen: Palpate from the RIF toward the left hypochondrium. Enlarged spleen moves with respiration, has a notch, cannot get above it.
  • Kidneys: Bimanual palpation ("ballottement"). Right kidney is slightly lower. Kidneys are palpable in neonates and thin infants normally.
  • Assess for renal masses (Wilms' tumour - unilateral, smooth, does not cross midline).
Percussion: Liver and splenic size; shifting dullness if ascites suspected (>500 mL needed to detect clinically).
Genitalia and hernial orifices: Always examine; inspect Tanner staging in adolescents.
Hernias:
  • Inguinal hernia: More common in boys, premature infants. Indirect type. Reduces with pressure and lying. Risk of strangulation.
  • Umbilical hernia: Extremely common; typically resolve spontaneously.

D. Neurological

Conscious level: AVPU (Alert, responds to Voice, responds to Pain, Unresponsive) or GCS paediatric version.
Tone:
  • Observe posture and spontaneous movement.
  • "Floppy infant" = hypotonia. Central vs peripheral: central hypotonia usually has preserved reflexes and brisk DTRs; peripheral (LMN) has absent/reduced reflexes.
Power: Observe functional tasks (reaching, walking). Formal MRC grading in older children.
Reflexes:
  • Deep tendon reflexes: biceps (C5-6), triceps (C7), knee (L3-4), ankle (S1-2).
  • Primitive reflexes (neonatal): should disappear by stated ages:
ReflexStimulusResponseDisappears
RootingTouch cheekHead turns to that side4 months
SuckingObject in mouthSucking movement4 months
MoroSudden drop of headArms abduct then adduct4-6 months
Palmar graspPressure on palmFinger flexion3-4 months
Plantar (Babinski)Stroke lateral soleToe extension12-18 months
Tonic neck (ATNR)Head turned to sideIpsilateral arm extends4-6 months
ParachuteHeld vertically, tilted forwardArms extend forwardPermanent from 8-9 months
Cranial nerves: Observe eye movements, facial symmetry, bulbar function (feeding, cry).
Cerebellar: Gait, finger-nose (from age ~3), heel-shin, dysdiadochokinesis, nystagmus.

E. Musculoskeletal / Developmental

  • Hips: Barlow and Ortolani tests in neonates. Galeazzi sign. From 6+ months, assess gait.
  • Spine: Scoliosis screen (Adams forward bend test from ~6 years).
  • Gait: Observe walking, running; age 1-3 years have a wide-based toddler gait (normal).
  • Feet: Talipes, flat feet (usually physiological to age 7-8), in-toeing.

F. ENT

  • Ear: Otoscope; note position (low-set ears = Turner's, Down's, renal anomalies). Look for discharge, perforation, effusion ("glue ear").
  • Nose: Obstruction, discharge, septal deviation.
  • Throat: Tonsil size (Brodsky grading 1-4+), pharyngeal erythema, exudate, Koplik's spots (measles), strawberry tongue (Kawasaki, scarlet fever).

G. Skin and Lymph Nodes

Lymph nodes:
  • Up to 1 cm cervical lymph nodes are normal in children.
  • Supraclavicular nodes are always pathological.
  • Note: size, consistency, tenderness, mobility, overlying skin changes.
Neonatal skin findings:
  • Mongolian blue spots: benign, common in dark-skinned infants; lumbar/sacral; fade by age 5.
  • Erythema toxicum: benign pustules, days 1-3.
  • Milia: tiny white sebaceous cysts on nose/face; resolve spontaneously.
  • Port wine stain (Sturge-Weber association if V1 distribution).
  • Café-au-lait spots: >5, >0.5 cm = consider neurofibromatosis type 1.

2.6 Developmental Assessment

Always assess alongside anthropometry - growth and development are interlinked.
Key developmental milestones:
AgeGross MotorFine MotorLanguageSocial
6 weeksHead lag reduced; lifts head proneFixes on faceCoosSmiles socially
3 monthsHolds head steadyHolds rattleVocalisesRecognises mother
6 monthsSits with support; rollsPalmar graspBabblesStranger anxiety starts
9 monthsStands holding on; crawlsPincer grip developing"Dada/mama" (non-specific)Waves bye-bye
12 monthsWalks with one hand heldNeat pincer grip1-2 words (specific)Points with index finger
18 monthsWalks independentlyScribbles; tower of 3 cubes6-10 wordsParallel play
2 yearsRuns; up/down stairsTower of 6 cubes50+ words; 2-word sentencesSymbolic play
3 yearsTricycle; stairs alternating feetCopies circle; tower of 93-word sentences; ~250 wordsGroup play
4 yearsHops; catches ballCopies cross; dresses self1500 words; tells storiesCooperative play
5 yearsSkipsCopies square; ties laces2000+ words; reads simple wordsRule-based games
Red flags:
  • No social smile by 8 weeks
  • No babble by 12 months
  • No pointing/waving by 12 months
  • No single words by 16 months
  • No 2-word phrases by 24 months
  • Any regression at any age

2.7 Neonatal Examination (NIPE - Newborn Infant Physical Examination)

Performed within 72 hours of birth (and at 6-8 weeks). A structured screen for:
  1. Eyes - Red reflex bilaterally (absent = congenital cataract, retinoblastoma)
  2. Heart - Murmurs, femoral pulses (coarctation), four-limb saturations
  3. Hips - Ortolani and Barlow (developmental dysplasia of the hip - DDH)
  4. Testes - Descended bilaterally; undescended testes must be referred
Additional NIPE checks:
  • Palate intact (finger through mouth - submucosal clefts are missed by inspection alone)
  • Moro reflex
  • Tone and posture
  • Fontanelles: anterior (closes 12-18 months), posterior (closes 6-8 weeks)
  • Spine: sacral dimple, hair tuft, lipoma = spinal dysraphism
  • Anus: patent
  • Genitalia: normal configuration, hypospadias

2.8 The 6-8 Week Check

  • Full general examination
  • Growth: weight, length, OFC - plot on centile chart
  • Developmental milestones (smiling, fixing/following, head control)
  • Immunisation history
  • Feeding history
  • Maternal mental health (Edinburgh Postnatal Depression Score)
  • Hip check
  • Eye: red reflex, fixes and follows
  • Hearing: screen was at birth; parental concerns

PART 3 - INTEGRATED ASSESSMENT IN THE CLINIC

3.1 Nutritional Assessment (ABCDE)

ComponentWhat it Covers
A - AnthropometryWeight, height, OFC, MUAC, skinfolds, indices (WFA, HFA, WFH, BMI)
B - BiochemicalHb, albumin, serum proteins, micronutrients
C - ClinicalPhysical signs of deficiency (oedema, dermatosis, hair changes, eye signs)
D - Dietary24-hr recall, food frequency, feeding history
E - EnvironmentalSocioeconomic, hygiene, access to food, infections

3.2 Common Nutritional Signs to Examine For

SignDeficiency
Bitot's spotsVitamin A
Corneal clouding/xerophthalmiaSevere Vitamin A
Glossitis, angular cheilitisB2 (riboflavin), B3, iron
KoilonychiaIron
Rickets (bow legs, Harrison's sulcus, craniotabes, rosary)Vitamin D / Calcium
Scurvy (subperiosteal bleeding, perifollicular haemorrhage)Vitamin C
Pitting oedema + skin changes + hair changeKwashiorkor (protein)
Severe wasting + no oedemaMarasmus (energy-protein)
GoitreIodine
Pellagra (4 Ds: dermatitis, diarrhoea, dementia, death)Niacin (B3)

PART 4 - QUICK REFERENCE SUMMARY

Anthropometry Equipment Checklist for Clinic

  • Calibrated digital infant scale (0-10 kg, to 10 g)
  • Adult scale with paediatric range
  • Infantometer (length board) for <2 years
  • Wall-mounted stadiometer for ≥2 years
  • Non-stretch measuring tape (OFC, MUAC, chest)
  • WHO Growth Charts (age/sex appropriate, 0-2 and 2-18 yrs)
  • MUAC tape (tri-colour for 6 months - 5 years)
  • Harpenden skinfold callipers (optional, specialist use)

Key Formulas

ParameterFormula
Minimum systolic BP (1-10 yr)70 + (2 × age in years) mmHg
Estimated weight (1-10 yr)2 × (age in years + 4) kg
Estimated weight (1-5 yr, simpler)age × 2 + 8 kg
Normal RR upper limitDecreases with age (see table above)

Key Sources

  • Park's Textbook of Preventive and Social Medicine - covers anthropometry in nutritional assessment (Chapter 11)
  • The Harriet Lane Handbook, 23rd Edition (Johns Hopkins) - paediatric vital signs, examination norms
  • Red Book 2021, Committee on Infectious Diseases (AAP) - newborn screening
  • WHO Multicentre Growth Reference Study (MGRS) - growth standards 0-5 years
  • RCPCH UK-WHO Growth Charts - centile and z-score references
  • NICE Guideline CG160 - Fever in under 5s (traffic light system)

Tell me holiday cegar formula

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Excellent - the Harriet Lane Handbook gives the full formula with worked examples. Here is the complete guide:

Holliday-Segar Formula

The Holliday-Segar method (published 1957 by Holliday MA & Segar WE, Pediatrics) is the standard formula for calculating maintenance IV fluid requirements in children. It estimates caloric expenditure by weight category, assuming ~100 mL water is needed per 100 kcal metabolised.

The Formula

Body WeightDaily RateHourly Rate (the "4-2-1 rule")
First 10 kg100 mL/kg/day4 mL/kg/hr
Second 10 kg (10-20 kg)50 mL/kg/day2 mL/kg/hr
Each kg above 20 kg20 mL/kg/day1 mL/kg/hr
The hourly version (4-2-1) is what you use at the bedside.

How to Calculate - Step by Step

Daily volume:
  • First 10 kg: 10 × 100 = 1000 mL
  • Next 10 kg (10-20 kg): 10 × 50 = 500 mL
  • Each kg above 20 kg: × 20 mL
Hourly rate:
  • First 10 kg: 10 × 4 = 40 mL/hr
  • Next 10 kg: 10 × 2 = 20 mL/hr
  • Each kg above 20 kg: × 1 mL/hr

Worked Examples

Example 1: Child weighing 8 kg
  • All weight in first 10 kg bracket
  • Daily: 8 × 100 = 800 mL/day
  • Hourly: 8 × 4 = 32 mL/hr
Example 2: Child weighing 15 kg
  • First 10 kg: 1000 mL/day (40 mL/hr)
  • Next 5 kg: 5 × 50 = 250 mL/day (5 × 2 = 10 mL/hr)
  • Total: 1250 mL/day = 50 mL/hr
Example 3: Child weighing 25 kg (from Harriet Lane Handbook)
  • First 10 kg: 1000 mL/day (40 mL/hr)
  • Second 10 kg: 500 mL/day (20 mL/hr)
  • Remaining 5 kg: 5 × 20 = 100 mL/day (5 × 1 = 5 mL/hr)
  • Total: 1600 mL/day = 65 mL/hr

Quick Mental Formula (Summary)

WeightDaily Fluid
≤10 kgWeight × 100 mL
11-20 kg1000 + (weight - 10) × 50 mL
>20 kg1500 + (weight - 20) × 20 mL

Important Notes

  1. Not for neonates <14 days old - the formula overestimates fluid needs in newborns. Use dedicated neonatal fluid protocols instead.
  2. Maximum rate: Experts recommend a maximum of 120 mL/hr in the absence of cardiac, hepatic, or renal pathology. Lower the rate if there is risk of fluid overload.
  3. Fluid type (updated guidance): The original Holliday-Segar paper recommended hypotonic fluids (¼ NS) based on the electrolyte composition of human milk. However, AAP guidelines (2018) now recommend isotonic fluids (0.9% NaCl or Hartmann's/Lactated Ringer's) as the maintenance fluid of choice for most hospitalised children, to prevent hospital-acquired hyponatraemia. The volume calculated by Holliday-Segar remains valid; the composition has changed.
  4. Total body water (TBW) = 60% of body weight in kg (75% in infants) - used alongside Holliday-Segar when calculating dehydration deficits.
  5. Adjust upward for:
    • Fever (+12% per 1°C above 37.5°C)
    • Increased insensible losses (burns, phototherapy, high ambient temperature)
    • Ongoing losses (diarrhoea, vomiting, drains)
  6. Adjust downward for:
    • SIADH / fluid retention states
    • Oliguric renal failure
    • Post-operative states (ADH release increases fluid retention)
    • Cardiac or hepatic disease

Electrolyte Requirements (Original Holliday-Segar)

Per 100 mL water metabolised:
  • Sodium: ~3 mEq
  • Potassium: ~2 mEq
(Again, fluid composition is now guided by AAP 2018 isotonic fluid recommendations rather than these original calculations.)

Source: The Harriet Lane Handbook, 23rd Edition (Johns Hopkins Hospital), Chapter 11 - Fluids and Electrolytes; original paper: Holliday MA, Segar WE. The maintenance need for water in parenteral fluid therapy. Pediatrics. 1957;19(5):823-832.
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