In microscopy of breast carcinoma in morphology of it is the basement

In microscopy of breast carcinoma in morphology of it is the basement membrane breached or intact

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Here is a clear, textbook-sourced answer to your question:

Breast Carcinoma: Basement Membrane - Breached or Intact?

The answer depends entirely on whether the carcinoma is in situ or invasive. This distinction is the single most important morphologic feature in breast carcinoma.

Carcinoma In Situ - Basement Membrane INTACT

In ductal carcinoma in situ (DCIS) and lobular carcinoma in situ (LCIS), the malignant cells are confined within ducts and lobules - the basement membrane is intact and not breached.

As Robbins Pathology states: "Carcinoma in situ refers to cancer cells confined within ducts and lobules by a basement membrane."
Robbins & Kumar Basic Pathology adds: "Both [DCIS and LCIS] 'respect' the basement membrane and do not invade into stroma or lymphovascular vessels."
Myoepithelial cells are generally preserved in involved ducts/lobules in DCIS.
Because the basement membrane is intact, there is no metastatic potential in true in situ disease.

Histologic patterns of DCIS (all with intact basement membrane):

Pattern	Feature
Comedo type	High-grade cells with central necrosis and calcifications
Cribriform	Rounded "cookie-cutter" spaces
Micropapillary	Bulbous protrusions without fibrovascular cores
Papillary	True papillae with fibrovascular cores, lacking myoepithelial cells

Invasive (Infiltrating) Carcinoma - Basement Membrane BREACHED

In invasive ductal carcinoma (now called "No Special Type" / NST) and invasive lobular carcinoma, malignant cells have broken through the basement membrane into the surrounding stroma.

Bailey & Love's Surgery states: "Infiltration of the surrounding tissue through a breach in the basement membrane leads to 'invasive or infiltrative' ductal or lobular carcinoma."
Sabiston Surgery notes: "The basement membrane layer is an important boundary, differentiating noninvasive breast cancer (DCIS) from invasive breast cancer. Invasion or infiltration across this boundary confers metastatic potential."

Histology Image - In Situ Carcinoma (Intact Basement Membrane)

In situ carcinoma - DCIS and LCIS histology

(A) DCIS - distorted lobular spaces with calcified secretory material. (B) LCIS - monomorphic cells filling the lobule. (C) Comedo DCIS - central necrosis and calcifications. (D) Mammogram showing linear ductal calcifications of DCIS.

Summary Table

Type	Basement Membrane	Metastatic Risk
DCIS	Intact	None (local recurrence only)
LCIS	Intact	None (risk marker for future cancer)
Invasive carcinoma	BREACHED	Present - can spread to nodes and distant sites

Special note - Paget disease of the nipple: DCIS cells extend up lactiferous ducts into nipple skin without crossing the basement membrane, so this remains classified as in situ disease even though it involves the skin.

Sources: Robbins, Cotran & Kumar Pathologic Basis of Disease; Robbins & Kumar Basic Pathology; Bailey & Love's Short Practice of Surgery 28th Ed; Sabiston Textbook of Surgery.

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