A clinical definition requires nasal blockage or drainage plus facial pain/pressure or reduced smell. Goldman-Cecil Medicine, p. 4166.
Most cases are viral and improve without antibiotics. Bacterial acute rhinosinusitis is more likely when any of these occur:
This approach is consistent with
CDC adult outpatient guidance. About 90-98% of acute rhinosinusitis cases are viral.
Antibiotics do not treat viral sinusitis and can cause side effects and antibiotic resistance. Imaging is generally unnecessary in uncomplicated acute cases. Textbook of Family Medicine 9e, p. 421.
A clinician may use
watchful waiting for mild uncomplicated illness when follow-up is reliable. If antibiotics are needed,
amoxicillin or amoxicillin-clavulanate is commonly first-line in adults. Antibiotic choice, dose, and duration should be individualized, especially for children, pregnancy, medication allergy, recent antibiotic use, kidney disease, or severe illness. CDC advises against routine azithromycin because of substantial pneumococcal resistance. See the
CDC sinus infection overview.
See a clinician if symptoms last over 10 days without improving, worsen after initially improving, recur frequently, or persist for 12 weeks or more.