Tuberculosis causative agent, transmission of disease. 2. Epidemic sit

Tuberculosis causative agent, transmission of disease. 2. Epidemic situation of tuberculosis in the world. Main epidemiological indicators (morbidity, mortality, prevalence). 3. Laboratory diagnostics of tuberculosis (bacterioscopic, bacteriological, molecular genetic). 4. Methods for timely detection of tuberculosis. 5. Prevention of tuberculosis. 6. Milliary and disseminated pulmonary tuberculosis, differential diagnostics. 7. Infiltrative pulmonary tuberculosis, differential diagnostics. 8. Pulmonary tuberculoma, differential diagnostics 9. Fibro-cavernous pulmonary tuberculosis, differential diagnostics. 10. Tuberculous pleurisy, differential diagnosis. 11. Pulmonary hemoptysis and bleeding in patients with tuberculosis. Diagnosis and treatment methods 12. Spontaneous pneumothorax as a complication of pulmonary tuberculosis, diagnosis, treatment. 13. Tuberculosis in combination with HIV infection, diagnosis, course features, treatment. 14. Tuberculosis, pregnancy, motherhood. 15. General principles of treatment of tuberculosis. Diagnostics and differential diagnostics

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tuberculosis epidemiology global incidence mortality

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WHO tuberculosis global epidemiology 2024 incidence mortality prevalence

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This guide covers all 15 of your TB topics. Here's a quick map of what's included:

Topics 1-5 (Microbiology, Epidemiology, Diagnostics, Detection, Prevention) cover the foundational science: M. tuberculosis biology and aerosol transmission, current WHO 2024 global data (10.7 million new cases, 1.23 million deaths), the full diagnostic ladder from ZN smear to Xpert MTB/RIF to WGS, active vs. passive case-finding, and BCG/LTBI treatment/IPC.

Topics 6-10 (Clinical Forms and Differential Diagnosis) cover each major radiological-clinical form: miliary (bilateral micronodular "snowstorm"), infiltrative (upper lobe exudative consolidation with cavitation), tuberculoma (round, calcified, with satellite lesions), fibro-cavernous (thick-walled fibrous cavities with destroyed lung), and TB pleurisy (lymphocytic exudate with high ADA >40 U/L as the key diagnostic marker).

Topics 11-15 (Complications and Special Situations) cover: hemoptysis management including bronchial artery embolization for massive bleeding; pneumothorax drainage and tension management; HIV/TB coinfection (atypical presentation, ART timing, drug interactions, IRIS); pregnancy safety profiles (streptomycin and aminoglycosides contraindicated); and the standard 2HRZE/4HR regimen plus the new WHO-recommended BPaLM regimen for MDR-TB.

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