Here is a thorough overview of Smith+Nephew's knee replacement implant portfolio as of mid-2026:
Smith+Nephew Knee Replacement Implant Systems
1. JOURNEY II Total Knee Arthroplasty (TKA)
The flagship kinematic system, designed around the philosophy of replicating the normal, healthy knee.
- Key design features: Reproduces normal femoral shapes, restores midline A/P position and 3° varus joint-line, and mimics natural knee motion (rollback, rotation)
- Goal: Improve patient satisfaction and function in active/demanding patients who found standard TKA "not feeling normal"
- Variants:
- JOURNEY II BCS (Bi-Cruciate Stabilized) - preserves both cruciate ligament functions without requiring them
- JOURNEY II CR (Cruciate Retaining)
- JOURNEY II PS (Posterior Stabilized)
- JOURNEY II ROX - newer version with CONCELOC porous ingrowth and OXINIUM bearing technology for cementless fixation
- JOURNEY II UK (Unicompartmental) - partial knee replacement for single-compartment disease
- Technology pairing: Designed for use with the CORI robotic surgical system and VISIONAIRE cutting guides
2. LEGION Total Knee System
A versatile, workhorse system for primary and revision TKA.
- Design approach: Customisable options to address diverse patient needs and complex intraoperative scenarios
- Variants:
- LEGION CR (Cruciate Retaining) - including Porous CoCo (cementless) option
- LEGION PS (Posterior Stabilized)
- LEGION Narrow CR/PS - for smaller anatomy
- LEGION Revision Knee (RK) - for failed primary replacements
- LEGION Hinge Knee (HK) - for severely compromised ligamentous stability
- Key tech: Compatible with VERILAST Technology (OXINIUM femoral + highly cross-linked polyethylene = 30-year wear claim*) and VISIONAIRE patient-matched instrumentation
- Track record: One of S+N's longest-running systems with extensive registry data
3. GENESIS II
A trusted legacy system with decades of clinical data.
- Introduced in 1997; became the first OXINIUM implant in knee replacement
- Variants: CR (Cruciate Retaining), PS (Posterior Stabilized), High Flex inserts, SPC (Symmetric Posterior Condyles)
- Material technology: OXINIUM oxidized zirconium femoral component - combines ceramic-like wear resistance with the toughness of a metal alloy, reducing polyethylene wear
- Includes VERILAST Technology pairing (OXINIUM + XLPE)
- Still widely used; supported by MIS (Minimally Invasive Surgery) instruments
4. ANTHEM Total Knee System
Designed for global anatomic diversity - a relatively newer, internationally focused system.
- Developed with extensive morphological data on anatomical differences across ethnicities (Asian, Middle Eastern, Latin American, etc.)
- Features advanced femoral and tibial anatomic design for improved implant fit and coverage
- Backed by National Joint Registry (NJR) data and AOANJRR registry data
5. JOURNEY II UK (Unicompartmental Knee System)
A partial knee replacement for patients with disease limited to one compartment (usually medial).
- Preserves bone, both cruciate ligaments, and the healthy compartments
- Medial or lateral compartment options
- Can be performed with CORI robotic assistance or NAVIO (now being phased into CORI workflow)
6. LANDMARK Knee System (Upcoming - 2026/2027)
S+N's next-generation platform, described by their CEO as their "most differentiating knee system yet".
- Cementless version: On track to launch in H2 2026
- Cemented version: Expected H1 2027
- Key attributes:
- Combines kinematics from JOURNEY II with ease-of-use and personalization
- Tray-efficient design - optimized for ambulatory surgical centers (ASCs)
- Fills the gap of no cementless JOURNEY offering
- Designed to pair with CORI robotics
- Represents S+N's consolidation of multiple platforms into one next-gen system
Key Supporting Technologies
| Technology | Description |
|---|
| OXINIUM | Oxidized zirconium femoral bearing - ceramic hardness, metallic toughness. Reduces wear. |
| VERILAST | OXINIUM femur + XLPE liner combo - 30-year wear claim* |
| CORI Surgical System | Handheld robotic platform for precise implant positioning (imageless; no CT required) |
| VISIONAIRE | Patient-matched cutting guides using MRI/X-ray data |
| CONCELOC | Porous metal ingrowth surface for cementless fixation |
| XLPE | Highly cross-linked polyethylene liners for reduced wear |
Quick System Comparison
| System | Best For | Fixation | Cruciate Options |
|---|
| JOURNEY II | Active patients seeking natural feel | Cemented / Cementless (ROX) | CR, PS, BCS |
| LEGION | Complex primary & revision | Cemented / Porous cementless | CR, PS, Revision, Hinge |
| GENESIS II | Standard primary TKA, proven track record | Cemented | CR, PS, High Flex |
| ANTHEM | Diverse ethnic anatomies / global markets | Cemented | CR, PS |
| JOURNEY II UK | Single compartment disease | Cemented | Unicompartmental |
| LANDMARK | Next-gen primary TKA (launching 2026) | Cementless first, cemented later | TBD |
*30-year wear claim based on laboratory testing; long-term clinical equivalence not guaranteed.
For official product details and IFUs, visit
Smith+Nephew's orthopaedics page or contact your local S+N representative.