Ultrasound scan for kidney

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Kidney Ultrasound (Renal Sonography)

Ultrasound is the first-line imaging modality for the kidney - it is non-invasive, radiation-free, widely available, and provides real-time structural information. Here is a complete overview.

Indications

Renal ultrasound is used to evaluate:
  • Acute kidney injury (AKI) - to exclude urinary obstruction as a cause
  • Chronic kidney disease (CKD) - assess kidney size, echogenicity, and chronicity
  • Hydronephrosis - grading and identifying the level of obstruction
  • Renal colic / suspected stones - detect nephrolithiasis
  • Urinary tract infection (UTI) - especially in children; detect congenital anomalies, abscess, or pyonephrosis
  • Haematuria - detect masses, cysts, or stones
  • Hypertension - evaluate kidney size and detect renal artery abnormalities
  • Transplant kidney - monitor for rejection, perinephric collections, and vascular complications
  • Guidance for biopsy and percutaneous procedures
(Comprehensive Clinical Nephrology, 7th Ed.)

Technique

Probe and Patient Position

  • A curvilinear (convex) transducer is the standard choice. A phased array probe can be used as a substitute but offers inferior parenchymal detail.
  • Patient is typically supine, though lateral decubitus, oblique, or prone positions may be needed (especially for the left kidney, where overlying bowel gas is a challenge).
  • Acoustic windows:
    • Right kidney - imaged through the liver
    • Left kidney - imaged through the spleen
    • This avoids bowel gas interference.

Probe Positioning

  • Place the transducer in the mid- or anterior axillary line at the 10th rib interspace, orientation marker pointing toward the patient's head, angled slightly posteriorly.
  • Fan (tilt) anteriorly and posteriorly to image the kidney completely in longitudinal view.
  • Rotate 90 degrees counterclockwise for the short axis (transverse) view, then fan superiorly and inferiorly to image from pole to pole.
  • Color Doppler should always be added for global perfusion assessment and to differentiate vascular structures from dilated collecting systems.
Ultrasound probe orientation and kidney imaging technique
Fig. 5.4 - Probe orientation for kidney ultrasound. The right kidney is shown with color Doppler flow. (Comprehensive Clinical Nephrology, 7th Ed.)

Normal Sonographic Appearances

Normal kidney longitudinal and transverse views
Fig. 5.5 - Longitudinal (A) and transverse (B) views of a normal kidney. C = cortex; F = sinus fat; * = medullary pyramid; arrowhead = renal vein. (Comprehensive Clinical Nephrology, 7th Ed.)
FeatureNormal Finding
ShapeWell-defined, bean-shaped with echogenic capsule
Size9-12 cm in longitudinal plane (varies with body height)
CortexHypoechoic or isoechoic relative to liver/spleen
Medullary pyramidsAnechoic or hypoechoic compared to cortex; prominent in children
Columns of BertinCortical tissue separating pyramids (can hypertrophy and mimic a mass)
Sinus fatEchogenic; occupies inner kidney; encases collecting system
Collecting systemNot visible when undilated; any anechoic area in sinus fat raises suspicion for hydronephrosis
Transverse (short axis) viewC-shaped at midportion; circular at poles

Key Pathological Findings

1. Hydronephrosis

Appears as anechoic branching, interconnected areas in the collecting system (backlogged urine).
GradeFeatures
MildDilation of renal pelvis and calyces; parenchymal architecture intact
ModerateMedullary pyramids begin to flatten; increasing pelvicalyceal dilation
SevereBallooned pelvis and calyces; corticomedullary differentiation lost; thin parenchyma
  • If internal echoes are present within the hydronephrotic area → consider pyonephrosis (pus in the collecting system), especially with fever and flank pain.
  • Pitfall: Color Doppler differentiates blood vessels (show flow) from hydronephrosis (no flow). Parapelvic cysts can mimic hydronephrosis but are round, well-circumscribed, and not connected to the ureter.

2. Kidney Stones (Nephrolithiasis)

  • Appear as hyperechoic structures with posterior acoustic shadow (signal void beyond the stone).
  • On color Doppler: exhibit the "twinkling sign" - a rapidly alternating color Doppler signal that is more pronounced with rough-surfaced stones.

3. Echogenicity Changes (CKD / AKI)

  • Normal cortex is hypoechoic compared to liver.
  • Increased cortical echogenicity (cortex brighter than liver) = parenchymal disease (CKD, glomerulonephritis, diabetic nephropathy, etc.)
  • In CKD: kidneys become small and echogenic, with loss of corticomedullary differentiation.
  • In AKI: kidneys are often normal or slightly enlarged; echogenicity alone cannot distinguish cause.

4. Renal Cysts

  • Appear as smooth, round, anechoic structures with posterior acoustic enhancement.
  • Simple cysts: thin walls, no internal echoes = benign.
  • Complex cysts: internal echoes, septations, or thick walls = require further evaluation (CT or MRI).

5. Masses

  • Solid renal masses appear as hyper- or isoechoic lesions disturbing normal architecture.
  • Ultrasound is a screening tool; CT or MRI is needed for characterization.

6. Renal Vein Thrombosis

  • Kidney enlargement, loss of corticomedullary differentiation, linear echogenicity radiating from the renal hilum (from venous clot).
  • Doppler shows absent or reversed diastolic flow.

Doppler Assessment

ApplicationFinding
Color DopplerGlobal perfusion; differentiates vessels from hydronephrosis/cysts
Spectral Doppler (RI)Resistive Index (RI) = (Peak systolic velocity - End diastolic velocity) / Peak systolic velocity
Normal RI< 0.70
Elevated RI (>0.70)Suggests obstruction, rejection (transplant), or parenchymal disease
Renal artery stenosisPeak systolic velocity > 180-200 cm/s at stenosis; dampened waveform ("tardus-parvus") distally

Limitations of Renal Ultrasound

  1. Operator-dependent - image quality and interpretation vary with experience.
  2. Bowel gas - can obscure the left kidney.
  3. Body habitus - difficult in obese patients.
  4. Not sensitive for acute pyelonephritis - abnormalities found in only 20-69% vs. 40-92% with DMSA scintigraphy.
  5. Not diagnostic for vesicoureteral reflux (VUR) or kidney scarring.
  6. False negatives for hydronephrosis - can occur with acute/partial obstruction, volume depletion, or retroperitoneal fibrosis.
  7. Cannot assess function - functional studies (DMSA, MAG3 scintigraphy) or GFR measurement needed for functional information.

Clinical Decision Points

Clinical QuestionRole of Ultrasound
AKI - is it obstructive?Rule out hydronephrosis (high sensitivity)
CKD - how chronic?Small, echogenic kidneys = chronic; normal size with AKI = acute
Renal colicDetect stones and hydronephrosis; CT KUB more sensitive for small stones
HaematuriaScreen for mass, cyst, stone
Paediatric UTIDetect congenital anomalies (CAKUT), abscess, pyonephrosis
Transplant monitoringPerinephric collections, Doppler for rejection
Pre-biopsyConfirm kidney position, size, and guide needle placement

Sources: Comprehensive Clinical Nephrology, 7th Edition (Chapter 5 - Kidney and Bladder Ultrasound, p. 80-82); Brenner and Rector's The Kidney, 2-Volume Set (Imaging Tests chapter)
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