Acute stress reaction and ptsd nice guidelines

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NICE guidelines PTSD acute stress reaction NG116 2018 recommendations

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acute stress reaction PTSD diagnosis treatment recommendations

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PTSD drug treatment EMDR CBT adults children NICE NG116

Here is a structured summary of the NICE NG116 (2018, updated 2025) guidelines on acute stress reaction and PTSD.

NICE Guideline NG116: Post-Traumatic Stress Disorder (2018, updated 2025)


Definitions

Acute Stress Disorder (ASD) - a DSM-5 diagnosis applied in the first month after a traumatic event. Requires 9 or more symptoms across 5 categories: intrusion, negative mood, dissociation, avoidance, and arousal (symptoms must start or worsen after the event).
Acute Stress Reaction (ICD-11: QE84) - classified under ICD-11 as a normal reaction to an abnormal event, not a mental disorder. Symptoms are transient and expected to resolve without formal treatment.
Clinically important PTSD symptoms - symptoms that significantly impair functioning but don't reach full diagnostic threshold.
PTSD - symptoms persisting beyond 1 month. DSM-5 clusters: intrusion, avoidance, negative alterations in cognition/mood, hyperarousal.

Planning Treatment (1.6.1-1.6.3)

  • Use a holistic approach - consider all contributing factors, past treatment history, and patient preferences.
  • Provide information and support to enable informed choice.
  • Where there is significant risk of harm to self or others, establish a risk management and safety plan (involving family/carers where appropriate) as part of initial treatment planning.

Within the First Month After Trauma

Active Monitoring (1.6.4)

  • Consider active monitoring (watchful waiting) for adults with subthreshold PTSD symptoms within 1 month of trauma.
  • Arrange follow-up within 1 month.

Do NOT offer (1.6.5)

  • Do not offer psychologically-focused debriefing (e.g. Critical Incident Stress Debriefing) for prevention or treatment of PTSD - evidence shows it is ineffective and potentially harmful.

Adults with ASD or Clinically Important PTSD Symptoms within 1 Month (1.6.15)

  • Offer individual trauma-focused CBT (TF-CBT) - this is the recommended first-line intervention. Specific modalities include:
    • Cognitive processing therapy
    • Cognitive therapy for PTSD
    • Narrative exposure therapy
    • Prolonged exposure therapy

Drug Treatment in the First Month (1.6.24)

  • Do not offer drug treatments, including benzodiazepines, to prevent PTSD in adults.

Established PTSD (>1 month, or >3 months for EMDR)

Psychological Treatments - Adults (1.6.16-1.6.20)

Trauma-focused CBT (1.6.16-1.6.17)
  • Offer individual TF-CBT to adults with PTSD or clinically important symptoms.
  • Typically 8-12 sessions (more if multiple traumas).
  • Delivered by trained practitioners with ongoing supervision.
  • Must include:
    • Psychoeducation about trauma reactions
    • Strategies for managing arousal and flashbacks
    • Safety planning
    • Elaboration and processing of trauma memories
    • Processing trauma-related emotions (shame, guilt, loss)
    • Addressing trauma-related meanings for the individual
    • Help to overcome avoidance
    • Planning booster sessions (e.g. around trauma anniversaries)
EMDR (1.6.19-1.6.20)
  • Offer EMDR to adults with PTSD who have presented more than 3 months after a non-combat-related trauma.
  • Typically 8-12 sessions (more for multiple traumas).
  • Must be based on a validated manual, delivered by trained practitioners.
  • Delivered in a phased manner including: psychoeducation, managing distressing memories, identifying and treating target memories (often visual images), and promoting alternative positive beliefs.

Psychological Treatments - Children and Young People (1.6.6-1.6.13)

  • Within 1 month of trauma: consider active monitoring or individual TF-CBT for those under 18 with ASD or clinically important symptoms.
  • Group TF-CBT (1.6.7): consider for children aged 7-17 following large-scale shared trauma within the last month.
  • Established PTSD in children (>3 months): offer TF-CBT as first-line (12 sessions for single event; longer for chronic/recurrent trauma).
  • EMDR (1.6.13): consider for children aged 7-17 only if they do not respond to or engage with TF-CBT.

Drug Treatments - Adults (1.6.24-1.6.26)

RecommendationDetail
No drugs for prevention (1.6.24)Do not offer any drug treatment (including benzodiazepines) to prevent PTSD.
Venlafaxine or SSRI (1.6.25)Consider if the patient has a preference for drug treatment. Review regularly. Sertraline and paroxetine have UK marketing authorisation for PTSD; venlafaxine is off-label.
Antipsychotics (1.6.26)Consider risperidone in addition to psychological therapies to manage symptoms if TF-CBT/EMDR have failed or are declined, and there are severe, ongoing symptoms.
SSRIs with the best evidence in adults: fluoxetine, paroxetine, sertraline. Venlafaxine (SNRI) also supported.

Drug Treatments - Children and Young People (1.6.14)

  • Pharmacotherapy is not recommended for PTSD in children and young people (very limited evidence).
  • If comorbid disorders (depression, anxiety) require treatment, drugs may be considered to target those conditions specifically.

Key Practical Points

  • Do not delay or withhold treatment because of ongoing court proceedings or compensation claims.
  • Transitions between services: the referring team should not discharge the patient before a care plan is agreed in the new service.
  • Involve family members and carers where appropriate, both to support the patient and to address their own needs as carers.
  • Actively promote access to services - particularly for migrants, asylum seekers, and people with language or literacy needs.
  • PTSD can occur after a wide range of traumatic events (road traffic accidents, assault, childbirth, natural disasters, combat, etc.). Assessment should be thorough and consider all trauma history.

Summary Table

ScenarioRecommended Action
Subthreshold symptoms <1 monthActive monitoring, follow-up within 1 month
ASD / clinically important symptoms <1 month (adults)Offer individual TF-CBT
ASD / clinically important symptoms <1 month (children)Active monitoring or individual TF-CBT
Established PTSD >1 month (adults)Offer TF-CBT (8-12 sessions)
Non-combat PTSD >3 months (adults)Offer EMDR as alternative to TF-CBT
Established PTSD (children/young people)TF-CBT first-line; EMDR if TF-CBT fails
Patient prefers medication (adults)Sertraline/paroxetine (licensed) or venlafaxine (off-label)
Prevention of PTSD - drugsDo NOT offer (including benzodiazepines)
Psychological debriefingDo NOT offer

Source: NICE NG116 - Post-traumatic stress disorder (2018, updated 2025) | Maudsley Prescribing Guidelines in Psychiatry, 15th ed. | Kaplan & Sadock's Comprehensive Textbook of Psychiatry

Make a table of nice vs cpg guidelines of trestment for ptsd and acute stress reaction…and also give flow of psychotherapy

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