Respiratory system notes pdf
Respiratory System Notes
PDF Document · PDF
| # | Section | Highlights |
|---|---|---|
| 1 | Overview & Anatomy | Weibel model (23 airway generations), conducting vs respiratory zones, alveolar architecture, lung lobes |
| 2 | Lung Volumes & Capacities | Full table with TV, IRV, ERV, RV, TLC, VC, FRC, FEV1, FVC + obstructive vs restrictive patterns |
| 3 | Mechanics of Breathing | Compliance, airway resistance (Poiseuille's Law), work of breathing, surfactant and Laplace's Law |
| 4 | Ventilation & Dead Space | Minute ventilation, alveolar ventilation, Bohr equation, alveolar gas equation with worked values |
| 5 | Pulmonary Circulation | Pulmonary vs systemic pressures, hypoxic pulmonary vasoconstriction (HPV), West's Zones 1-3 |
| 6 | Gas Exchange & Diffusion | Fick's Law, DLCO, causes of hypoxaemia table (shunt vs V/Q mismatch vs diffusion) |
| 7 | O2 & CO2 Transport | O2 content formula, oxyhaemoglobin dissociation curve (right/left shifts, Bohr effect), CO2 transport forms, Haldane effect |
| 8 | Control of Breathing | Medullary/pontine centers, central vs peripheral chemoreceptors, hypoxic drive in COPD |
| 9 | V/Q Relationships | V/Q = 0 (shunt) vs V/Q = ∞ (dead space), vertical V/Q gradient in upright lung |
| 10 | Common Diseases | Asthma, COPD, ILD, pneumonia, PE, pneumothorax, pleural effusion, ARDS |
| 11 | Clinical Reference | ABG normal ranges, ABG interpretation framework, compensation rules, key equations quick-reference |