book_title | section_heading | file_path | line_start | line_end | snippet -----------+-----------------+-----------+------------+----------+--------- Lippincott Illustrated Reviews Pharmacology (Lippincott | A. Biguanides | /textbooks/9781975170561/9781975170561_block3.md | 1168 | 1170 | >>>Metformin<<< [met-FOR-min], the only >>>biguanide<<<, is the preferred initial therapy for type 2 diabetes, and the drug should be initiated upon diagnosis. It is also beneficial in the prevention of type 2 diabetes in patients with prediabetes. [Note... Lippincott Illustrated Reviews Pharmacology (Lippincott | Chapter Summary | /textbooks/9781975170561/9781975170561_block3.md | 1318 | 1330 | ...The >>>biguanide<<< >>>metformin<<< is the preferred initial agent for type 2 diabetes. The primary >>>mechanism<<< of action of >>>metformin<<< is reduced hepatic gluconeogenesis. The drug should be avoided in severe renal impairment or acute heart failure due to the risk... Swanson's family medicine review - a problem-oriented approach | ANSWERS | /textbooks/9780323698115/9780323698115_block4.md | 3019 | 3023 | ...>>>Metformin<<<, a second-generation >>>biguanide<<<, should also be con- sidered a first-line treatment option for PCOS be- cause it addresses the underlying problem of insulin resistance. Clinical studies have shown that women on >>>metformin<<< (500 mg three times a... Sleisenger and Fordtran's Gastrointestinal and Liver Disease | REFERENCES | /textbooks/9780323609623/9780323609623_block27.md | 378 | 386 | ...Malabsorption of vitamin B12 and intrinsic factor secretion during >>>biguanide<<< therapy. Diabetolo-gia 1983;24:16-8. L. T. Lundgren-B. A. Snyder-H. et al. >>>Metformin<<< induces reduc-tions in plasma cubin, and biopterin bound cobalamin complex. In: Chandler... Brenner and Rector's The Kidney, 2-Volume Set | CAN RENAL AGING BE MODIFIED? | /textbooks/9780323532655/9780323532655_block13.md | 2566 | 2566 | ...Other agents, such as the >>>biguanide<<< >>>metformin<<<, may also have antiaging effects via an action on the AMPK/