I now have rich content from Miller's, Barash (Stoelting), and Morgan & Mikhail. Let me compile the comprehensive viva-style overview.
Pediatric Anesthesia for Adenotonsillectomy: Viva Overview
Sources: Miller's Anesthesia 10e, Morgan & Mikhail's Clinical Anesthesiology 7e, Barash/Stoelting's Clinical Anesthesia 9e
1. INDICATIONS FOR ADENOTONSILLECTOMY
Q: What are the indications for adenotonsillectomy in children?
- Recurrent/chronic tonsillitis (most common) - typically defined as >7 episodes/year or >5/year for 2 consecutive years
- Peritonsillar abscess
- Tonsillar/adenoidal hyperplasia with airway obstruction
- Obstructive Sleep Apnea Syndrome (OSAS) - most important anesthetic concern
- Failure to thrive, speech disorders, dental abnormalities from chronic obstruction
- Cardiac valvular disease with recurrent streptococcal bacteremia
- Malignant disease (lymphoma - important caveat for dexamethasone use)
(Barash 9e, p.4079)
2. PREOPERATIVE EVALUATION - KEY VIVA POINTS
Q: What is your preoperative focus for this child?
A - Airway assessment:
- Size of tonsils and adenoids
- Degree of nasopharyngeal obstruction
- Mouth opening, neck mobility
B - Screen for OSAS:
- Snoring, witnessed apneas, restless sleep, daytime somnolence, nocturnal enuresis, behavioral changes
- The "gold standard" is polysomnography (PSG)
- Apnea-Hypopnea Index (AHI): severe OSA = AHI >10 AND oxygen saturation nadir <80%
- Barash: "Despite only mild-to-moderate tonsillar enlargement, these patients have upper airway obstruction while awake and apnea during sleep - do not underestimate severity based on tonsillar size alone"
C - Cardiac comorbidities from chronic OSAS:
- Cor pulmonale - right ventricular hypertrophy, cardiomegaly
- Pulmonary hypertension, systemic hypertension
- ECG for RVH; CXR for cardiomegaly
- Each apneic episode spikes pulmonary artery pressure further
D - Recent URTI:
- Active fever or productive cough = grounds for postponement
- Recent URTI within 2-4 weeks increases risk of laryngospasm, bronchospasm
E - Coagulation status:
- History of bleeding, family bleeding history
- Platelet count, clotting screen if indicated
F - Obesity:
- Obese children: especially high risk for OSA, opioid sensitivity, respiratory arrest post-op
(Miller 10e, Morgan 7e, Barash 9e)
3. PEDIATRIC AIRWAY - ANATOMICAL DIFFERENCES (VIVA FAVORITE)
Q: How is the pediatric airway different from adult?
| Feature | Pediatric | Clinical Implication |
|---|
| Head | Proportionately larger | Sniffing position - less neck extension needed |
| Tongue | Larger relative to oral cavity | Higher risk of obstruction |
| Larynx | Anterior and cephalad (C3-C4 vs C4-C5 in adult) | More anterior - view can be difficult |
| Epiglottis | Longer, floppy, U-shaped | Use straight blade (Miller) for better lift |
| Narrowest point | Cricoid ring (<5 years) vs glottis in adults | Uncuffed tube may leak; cuffed tubes now safe if chosen correctly |
| Trachea | Shorter | Higher risk of endobronchial intubation |
| Nasal breathers | Until ~5 months | Obligate nasal breathers - blocked nose = respiratory distress |
| FRC | Reduced (chest wall very compliant) | Rapid desaturation during apnea |
(Morgan & Mikhail 7e, p.1671; Barash 9e)
Q: What is the formula for uncuffed ETT size?
- (Age/4) + 4 for uncuffed; (Age/4) + 3.5 for cuffed
- Confirm with air leak at 15-20 cmH2O (uncuffed) or cuff pressure <20 cmH2O
4. ANESTHETIC INDUCTION
Q: How would you induce anesthesia?
Inhalational induction (preferred in children):
- Sevoflurane is the agent of choice - greater therapeutic index than halothane
- MAC of sevoflurane is highest in infants (2.5%) vs adults (2.0%)
- Inhalational induction followed by IV cannulation
- Glycopyrrolate 10 mcg/kg IV after IV access - reduces secretions, attenuates bradycardia
IV induction (if IV access present or older child):
- Propofol 3-4 mg/kg + fentanyl 1-2 mcg/kg
- Ketamine useful if haemodynamically compromised
Q: What is important about MAC in pediatric patients?
- MAC is highest in infants (not neonates), decreasing with age
- Exception: sevoflurane MAC shows no difference between neonates and infants
- Physiological reason: higher alveolar ventilation/FRC ratio, greater cardiac output to vessel-rich group = faster wash-in of volatile agents
(Morgan & Mikhail 7e)
5. AIRWAY DEVICE
Q: ETT or LMA for adenotonsillectomy?
Options:
- Oral RAE (Ring-Adair-Elwyn) preformed ETT - most commonly used; taped in the midline to mandible; keeps tube out of surgical field; risk of kinking with mouth gag
- Wire-reinforced (armored) ETT - resistant to kinking
- Flexible LMA - used in some centers; kinking/displacement with Boyle-Davis gag is a concern; requires experienced team; advantage of avoiding laryngoscopy
Key points:
- Tube taped in midline of mandible (not corner of mouth)
- After gag placement: always recheck tube position - kinking or displacement is not uncommon
- ETT cuff inflation pressure must be checked after position change (neck extension for surgery)
- Throat pack placement by surgeon - mandatory documentation, must be removed before extubation
(Miller 10e, p.9812; Barash 9e)
6. MAINTENANCE OF ANESTHESIA
Q: What agents do you use for maintenance?
- Either volatile (sevoflurane/isoflurane) or TIVA (propofol infusion) - both acceptable
- TIVA preferred by some due to reduced PONV, no theatre pollution, cleaner emergence
- Opioids: Fentanyl or morphine (use cautiously in OSA - reduce dose by up to 50%)
- Dexamethasone 0.15-0.5 mg/kg IV: reduces PONV, reduces postoperative swelling, improves oral intake
- CONTRAINDICATED if lymphoma is suspected - may cause lethal hyperkalemia from tumor lysis
- NSAIDs (e.g., ketorolac, ibuprofen): good evidence for analgesia without increased bleeding risk, though some surgeons avoid
- Paracetamol/acetaminophen: inadequate alone for tonsillectomy pain
- Ondansetron for PONV prophylaxis
- Local anaesthetic infiltration to tonsillar bed (with or without epinephrine) by surgeon - caution: injection into tonsillar vessels beneath tonsillar bed can cause seizures or cerebral infarction
(Miller 10e; Barash 9e, p.10647)
Q: Why avoid NSAIDs in some centers?
- Theoretical concern about platelet dysfunction and post-tonsillectomy haemorrhage
- Evidence: bleeding rate NOT significantly increased with NSAIDs; most guidelines support their use
- Individual surgeon/institutional preference governs
7. OSA AND OPIOID SENSITIVITY - CRITICAL VIVA POINT
Q: Why are OSA children sensitive to opioids?
- Chronic intermittent hypoxemia upregulates central opioid receptors
- Altered CO2 response curves - blunted hypercapnic drive
- Risk of post-op respiratory arrest even with standard doses
- Reduce opioid dose by up to 50% in OSA patients (Barash 9e, Key Point 3)
- Maximize non-opioid multimodal analgesia
8. EXTUBATION - DEEP vs. AWAKE
Q: When do you extubate - deep or awake?
Awake extubation (more common, safer overall):
- Patient regains protective airway reflexes
- Reduces risk of airway obstruction post-extubation
- Risk: coughing/bucking on tube may trigger bleeding from surgical site
Deep extubation:
- Smoother emergence, less coughing/straining
- Reduces bleeding risk from Valsalva-like maneuvers
- Risk: airway obstruction - must be managed in high-dependency environment
- Only appropriate if very experienced team and environment capable of rapid detection/management of obstruction
Adjuncts for smooth emergence (awake route):
- Lignocaine (lidocaine) 1.5 mg/kg IV or topical down ETT (cuff deflated)
- Light remifentanil infusion during emergence
- Suction oropharynx thoroughly + remove throat pack before extubation
- Pass orogastric tube to decompress stomach (swallowed blood/secretions)
(Miller 10e, p.9812)
9. COMPLICATIONS
A. Post-Tonsillectomy Haemorrhage (PTH) - MOST FEARED COMPLICATION
Q: How do you manage a child with post-tonsillectomy haemorrhage?
Primary (within 6 hours): often from inadequate surgical haemostasis
Secondary (days 5-10): usually infective sloughing of eschar
Anaesthetic management - key principles:
- Volume resuscitate first - IV access, fluids, blood if needed; hypovolemia reduces induction drug requirement - consider etomidate
- Treat as full stomach - significant swallowed blood in stomach
- Rapid sequence induction (RSI) with cricoid pressure - mandatory
- Prepare for difficult airway - bleeding + swelling + anxious child = previously easy laryngoscopy can quickly become impossible
- Have multiple laryngoscope sizes/blades available
- Videolaryngoscope on standby
- Have smaller ETT sizes ready
- Vigorous suction needed during laryngoscopy
- Surgeon must be present and scrubbed before induction
(Miller 10e, p.9812; Barash 9e, Key Point 4)
B. Laryngospasm
- Most common airway complication in pediatric anesthesia
- Risk factors: light anesthesia, secretions/blood, recent URTI
- Treatment: CPAP, jaw thrust, deepen anesthesia (propofol 0.5-1 mg/kg), suxamethonium 1-2 mg/kg IV (or 4 mg/kg IM) if complete
C. Negative Pressure Pulmonary Edema (NPPE)
- Occurs after sudden relief of chronic upper airway obstruction
- Mechanism: high negative intrapleural pressures (-30 cmH2O in obstruction vs. -10 cmH2O normally) increase venous return and disrupt pulmonary microvasculature
- Frothy pink fluid in ETT, SpO2 drop, bilateral interstitial infiltrates on CXR
- Prevention: apply moderate CPAP during induction to allow circulatory adaptation
- Treatment: supportive - oxygen, CPAP/PEEP, diuretics; usually resolves within 24 hours
(Barash 9e, p.4094-4095)
D. Post-operative Nausea & Vomiting (PONV)
- Very common - multimodal prophylaxis essential
- Dexamethasone + ondansetron + TIVA where possible
E. Airway Obstruction Post-extubation
- Especially with residual tonsillar tissue, edema, or in OSA children
- Lateral "tonsil position" (lateral decubitus) for recovery
10. OSA - POSTOPERATIVE DISPOSITION
Q: Who needs overnight admission after adenotonsillectomy?
Admit to hospital (Barash Table 48-1) if ANY of:
- Age <3 years
- Severe OSA (AHI >10, SpO2 nadir <80%)
- Cor pulmonale / cardiac abnormality
- Failure to thrive / poor oral intake
- Craniofacial abnormality
- Neuromuscular disorder
- Obesity (BMI >95th percentile)
- Sickle cell disease
- Post-op SpO2 <80% in recovery
- Bleeding concerns
- Lives far from hospital / no reliable carer
Day-surgery discharge criteria: no active bleeding, PONV controlled, adequate analgesia, adequate oral intake of fluids, SpO2 acceptable on room air for >1 hour, appropriate carer/distance.
11. PHARMACOLOGY REMINDERS (VIVA SPECIFICS)
| Drug | Dose | Notes |
|---|
| Sevoflurane MAC | ~2.5% (infant) | Higher than adult (2.0%) |
| Propofol induction | 3-4 mg/kg | Reduce in OSA/hypovolemia |
| Fentanyl | 1-2 mcg/kg | Reduce 50% in OSA |
| Dexamethasone | 0.15-0.5 mg/kg (max 8mg) | Avoid if lymphoma suspected |
| Ondansetron | 0.1 mg/kg (max 4mg) | PONV prophylaxis |
| Glycopyrrolate | 10 mcg/kg | Anti-sialagogue, attenuates bradycardia |
| Suxamethonium (laryngospasm) | 1-2 mg/kg IV; 4 mg/kg IM | Beware bradycardia in children |
| Lignocaine (smooth emergence) | 1.5 mg/kg IV | Or topical via deflated cuff |
12. SURGICAL SETUP - VIVA POINTS
- Position: supine, head ring, neck extended (shoulder roll)
- Mouth gag: Boyle-Davis gag - risk of ETT/LMA displacement, kinking; ALWAYS recheck after placement
- Throat pack: surgeon places; anaesthetist must document and ensure removal before extubation ("count" system)
- Shared airway: requires constant communication between surgeon and anaesthetist
SUMMARY ALGORITHM FOR THE CASE
Pre-op: Screen for OSA severity → Echo/ECG if cor pulmonale → Check coags → Postpone if active URTI/fever
Induction: Inhaled sevoflurane → IV access → glycopyrrolate → RSI if full stomach/PTH
Airway: Oral RAE ETT (midline taped) or flexible LMA
Maintenance: Volatile or TIVA + reduced-dose opioids (OSA) + dexamethasone + paracetamol + NSAID
Intraop: Check ETT after gag placement; monitor EtCO2, SpO2, temp
End of case: Remove throat pack + suction oropharynx + OGT to empty stomach
Extubation: Awake preferred; deep only if skilled team; lateral recovery position
Post-op: Multimodal analgesia; PONV prophylaxis; admit if OSA criteria met
Complication readiness: PTH → RSI protocol; Laryngospasm → sux protocol; NPPE → CPAP/PEEP
References:
- Miller's Anesthesia 10e, Ch. 27 & 29 - Tonsillectomy and Adenoidectomy
- Morgan & Mikhail's Clinical Anesthesiology 7e, Ch. 54 - Pediatric Anesthesia
- Barash/Stoelting's Clinical Anesthesia 9e, Ch. 48 - Anesthesia for Pediatric ENT Surgery