Here is the complete breakdown of all treatments prescribed on this sheet, with full clinical explanation:
Patient Diagnosis
CAD - Inferior Wall MI (IWMI) + Right Ventricular (RV) Involvement
- Killip Class assessed (noted as TMU - 3/14, likely day 3 of 14-day admission plan)
- NSR = Normal Sinus Rhythm on monitor
- No edema noted; patient appears hemodynamically stable
All Treatments - Full Detail
1. Inj. Clonita / Cannula 0.6 ml SC BD
Most likely: Subcutaneous Injection via cannula, 0.6 ml, Twice Daily
- Likely refers to Low Molecular Weight Heparin (LMWH) - Enoxaparin or a similar anticoagulant given subcutaneously
- In post-MI care, anticoagulation is given SC BD (twice daily) to prevent thrombus extension and DVT
- Alternatively could be insulin if the patient has diabetes - common in CAD patients
2. Tab. Deplatt-A 75/75 OD PC (After meals)
= Aspirin 75 mg + Clopidogrel 75 mg (combined tablet), Once Daily, After Food
This is Dual Antiplatelet Therapy (DAPT) - the cornerstone of post-MI treatment.
- Aspirin irreversibly inhibits COX-1, blocking thromboxane A2-mediated platelet aggregation
- Clopidogrel blocks the P2Y12 ADP receptor on platelets, preventing further clot formation
- Together they dramatically reduce the risk of re-infarction and stent thrombosis
- Guidelines recommend DAPT for 12 months after STEMI
- Taken after food to reduce GI irritation
"Dual antiplatelet therapy with aspirin and a P2Y12 receptor antagonist (clopidogrel, prasugrel, or ticagrelor) is recommended for 12 months after a STEMI." - Harrison's Principles of Internal Medicine, 22nd Ed.
3. Tab. Rosunn (Rosuvastatin) 40 mg OD NE (Night)
= Rosuvastatin 40 mg, Once Daily at Night
A high-intensity statin for:
- Plaque stabilization - prevents further rupture of vulnerable plaques
- LDL cholesterol reduction (target >50% reduction)
- Anti-inflammatory effects on the coronary endothelium
- Taken at night because cholesterol synthesis peaks at night
"Lipid-lowering therapy (high-intensity statin) regardless of LDL: target LDL reduction of ≥50%; give rosuvastatin 20-40 mg PO on admission and continue daily." - Goldman-Cecil Medicine
4. Tab. Telmo (Telmisartan) 20 mg OD W (With meals)
= Telmisartan 20 mg (ARB), Once Daily
An Angiotensin Receptor Blocker (ARB) used when ACE inhibitors are not tolerated (e.g., due to cough):
- Prevents adverse cardiac remodeling after MI (prevents the heart from dilating and weakening)
- Controls blood pressure
- Reduces mortality in post-MI patients with reduced ejection fraction
- Standard dose in post-MI is started low (20 mg) and titrated up
5. Tab. Pan (Pantoprazole) 40 mg OD BF (Before Food)
= Pantoprazole 40 mg (Proton Pump Inhibitor), Once Daily Before Breakfast
Gastroprotection - mandatory when on dual antiplatelet therapy:
- Aspirin + Clopidogrel significantly increases the risk of peptic ulcer and GI bleeding
- Pantoprazole suppresses gastric acid, protecting the stomach lining
- Taken on an empty stomach (before food) for maximum efficacy
6. Tab. Elpa / Alpha 0.25 mg OD NU (At Night)
Most likely: Alprazolam 0.25 mg or Clonazepam 0.25 mg, Once Daily at Night
A low-dose benzodiazepine/anxiolytic given at night:
- Post-MI anxiety and insomnia are common
- Reduces sympathetic overdrive which can trigger arrhythmias
- Standard admission orders for STEMI include "anxiolytic or hypnotic if needed"
- Very low dose (0.25 mg) suggests it is for mild anxiety/sleep aid only
7. Syp. Cremaffin Plus 20 ml OD NS (Night)
= Cremaffin syrup (liquid paraffin + milk of magnesia - a laxative), 20 ml, Once Daily at Night
Stool softener/laxative:
- Post-MI patients must avoid straining during bowel movements
- Straining triggers the Valsalva maneuver, which increases intrathoracic pressure, reduces cardiac preload, and can precipitate dangerous arrhythmias or re-infarction
- Cremaffin is a gentle osmotic + lubricant laxative widely used in Indian cardiac wards
"Stool softener" is explicitly listed in the Goldman-Cecil Medicine STEMI admission orders as standard care.
8. Inj. NS (Normal Saline) @ 100 ml/hr IV
= 0.9% Normal Saline infusion, running at 100 ml per hour
This is the most critical treatment specifically for RV Infarction:
- In RV MI, the right ventricle fails and cannot pump blood through the lungs adequately
- The right ventricle depends entirely on adequate preload (fluid) to maintain output
- IV fluid loading with NS is the primary treatment - it fills the RV and maintains cardiac output
- Nitrates, diuretics, and morphine are contraindicated in RV MI as they reduce preload and can cause catastrophic hypotension
"Management of right ventricular infarction consists of early maintenance of preload with intravenous fluids, reduction of RV afterload, early reperfusion, short-term inotropic support if needed, and avoidance of vasodilators (e.g., nitrates)." - Goldman-Cecil Medicine
+ ECG Post Leads (Circled note)
= Request for Right-sided ECG leads (V3R, V4R, V5R)
- Standard ECG only shows left-sided leads
- To confirm RV infarction, right-sided chest leads are applied
- ST elevation in V4R is the hallmark sign of RV MI
- This is why "post leads" / posterior leads are specifically requested
Summary Table
| # | Drug | Purpose | Why given |
|---|
| 1 | Inj. LMWH/Enoxaparin SC BD | Anticoagulation | Prevent thrombus extension |
| 2 | Deplatt-A 75/75 OD PC | Dual antiplatelet | Prevent re-occlusion |
| 3 | Rosuvastatin 40 mg ON | High-intensity statin | Plaque stabilization, LDL reduction |
| 4 | Telmisartan 20 mg OD | ARB | Prevent cardiac remodeling |
| 5 | Pantoprazole 40 mg OD | PPI gastroprotection | Protect GI from antiplatelet bleed |
| 6 | Alprazolam 0.25 mg ON | Anxiolytic/sleep | Reduce anxiety, sympathetic tone |
| 7 | Cremaffin 20 ml ON | Laxative | Prevent Valsalva/straining |
| 8 | NS @ 100 ml/hr IV | IV fluid preload | Critical for RV infarction management |
| + | ECG post (right-sided) leads | Diagnostic | Confirm RV infarction (V4R ST elevation) |
Note: This is a standard, evidence-based regimen for IWMI + RV involvement as taught in Goldman-Cecil Medicine and Harrison's Principles of Internal Medicine. The prescription follows current STEMI management guidelines. Drug names are interpreted from handwriting - always verify with the prescribing physician.