Here's your complete ECG guide β from absolute basics to disease patterns, drawn from Guyton & Hall, Ganong's Physiology, and Harrison's Principles of Internal Medicine.
π ECG: A Complete Guide β Basics to Disease
PART 1: What Is an ECG?
An ECG (electrocardiogram) records the electrical activity of the heart at the body surface. When a cardiac impulse travels through the heart, current spreads to surrounding tissue and reaches the skin β electrodes placed on the skin detect these tiny voltage changes and plot them over time.
The result is a trace of waves and intervals that tell you exactly what the heart's electrical system is doing.
"A normal ECG for two beats of the heart is shown in Fig. 11.1. The ECG is composed of a P wave, a QRS complex, and a T wave." β Guyton & Hall Textbook of Medical Physiology
PART 2: The 12 Leads β What Are They?
A standard ECG has 12 leads β 12 different "viewpoints" of the heart's electrical activity.
Limb Leads (Frontal Plane)
| Lead | What It Looks At |
|---|
| I | Left arm vs Right arm (lateral) |
| II | Left leg vs Right arm (inferior) |
| III | Left leg vs Left arm (inferior) |
| aVR | Right arm β looks INTO the cavity |
| aVL | Left arm β lateral wall |
| aVF | Left leg β inferior wall |
Precordial (Chest) Leads (Horizontal Plane)
Placed across the chest to look at the heart from front to back:
Normal ECG with tracings from each lead β note how the waveform morphology changes across the chest leads (Ganong's Review of Medical Physiology)
Precordial lead placement: V1βV6 (Harrison's Principles of Internal Medicine)
Key rule: A wave moving toward a lead electrode = positive (upward) deflection. Moving away = negative (downward) deflection.
PART 3: The ECG Waveforms β One by One
π΅ The P Wave
- Represents atrial depolarization (SA node β right atrium β left atrium)
- Normal: upright in lead II, inverted in aVR
- Duration: <120 ms | Amplitude: 0.1β0.3 mV
- Atrial repolarization is NOT seen β it's buried inside the QRS complex
π΄ The QRS Complex
- Represents ventricular depolarization β the electrical event just before ventricular contraction
- Made of 3 components:
- Q wave = initial septal depolarization (left β right)
- R wave = main ventricular depolarization
- S wave = late depolarization moving away from the electrode
- Normal duration: 0.06β0.10 sec (wider = conduction problem)
Two phases of ventricular depolarization: Phase 1 = septal (leftβright), Phase 2 = LV dominance (left-posterior). This explains the rS pattern in V1 and qR pattern in V6 (Harrison's)
π’ The T Wave
- Represents ventricular repolarization
- Normally upright in most leads (I, II, V3βV6)
- Normally inverted in aVR
- The T wave is broad because repolarization is not simultaneous β it spreads over ~0.15 sec
π‘ The U Wave (bonus)
- A small positive wave after the T wave
- May represent late Purkinje or M-cell repolarization
- Prominent U waves = think hypokalemia
PART 4: The Intervals β The Numbers You MUST Know
| Interval | What It Measures | Normal Value |
|---|
| PR interval | Atrial depolarization + AV node delay | 0.12β0.20 sec |
| QRS duration | Ventricular depolarization | < 0.10 sec (< 0.12 sec) |
| QT interval | Total ventricular activity (depolarization + repolarization) | ~0.35β0.44 sec (rate-corrected) |
| RR interval | Time between two beats | Used to calculate heart rate |
Heart rate formula: HR = 60 Γ· RR interval (in seconds)
- e.g., RR = 0.83 sec β HR = 72 bpm
ECG paper speed: 25 mm/sec
- 1 small box = 0.04 sec, 1 mm
- 1 large box = 0.20 sec, 5 mm
PART 5: A Systematic Approach to Reading Any ECG
Use this 7-step method every single time:
- Rate β count the RR interval β 60 Γ· RR (normal 60β100 bpm)
- Rhythm β regular or irregular? Is every QRS preceded by a P wave?
- Axis β is the QRS upright in lead I and aVF? (Normal axis = β30Β° to +90Β°)
- P waves β present? Normal shape? One per QRS?
- PR interval β 0.12β0.20 sec? (Long = heart block, short = pre-excitation)
- QRS β wide or narrow? Q waves present?
- ST & T waves β elevated? Depressed? Inverted?
PART 6: Common ECG Abnormalities in Disease
π΄ Myocardial Infarction (MI)
Three electrical events happen in infarcted tissue, all causing ST elevation in leads over the infarct:
| Event | Result |
|---|
| Rapid repolarization of dead cells | Current flows OUT of infarct β ST elevation |
| Decreased resting membrane potential | TQ depression β recorded as ST elevation |
| Delayed depolarization | Current flows OUT of infarct β ST elevation |
Timeline of ECG changes in MI:
| Time | ECG Finding |
|---|
| Minutes | Hyperacute tall T waves |
| Hours | ST elevation in leads over the infarct |
| HoursβDays | T wave inversion |
| DaysβWeeks | Pathological Q waves develop (dead, electrically silent muscle) |
Localization by leads:
| Leads with Changes | Territory | Artery |
|---|
| II, III, aVF | Inferior wall | Right coronary artery |
| V1βV4 | Anterior wall | LAD |
| I, aVL, V5βV6 | Lateral wall | LCx |
| V1βV2 (tall R, ST depression) | Posterior wall | RCA/LCx |
"The hallmark of acute myocardial infarction is elevation of the ST segments in the leads overlying the area of infarction. Leads on the opposite side of the heart show ST segment depression." β Ganong's Review of Medical Physiology
π‘ Heart Blocks (AV Blocks)
| Type | ECG Finding |
|---|
| 1st degree AV block | PR > 0.20 sec, all beats conducted |
| 2nd degree β Mobitz I (Wenckebach) | PR progressively lengthens, then a QRS drops |
| 2nd degree β Mobitz II | Fixed PR, sudden dropped QRS β more dangerous |
| 3rd degree (complete) AV block | P waves and QRS completely independent, slow escape rhythm |
π Bundle Branch Blocks
| Type | QRS | Key Feature |
|---|
| RBBB | Wide (>0.12 sec) | RSR' pattern in V1 ("rabbit ears"), wide S in V6 |
| LBBB | Wide (>0.12 sec) | Broad notched R in V5βV6, deep S in V1 |
Memory trick: In RBBB, the R Rabbit ears are in V1. In LBBB, the big R is on the Left (V5βV6).
π΅ Electrolyte Abnormalities
| Condition | ECG Clue |
|---|
| Hyperkalemia | Tall peaked T waves β wide QRS β no P waves β sine wave β VF |
| Hypokalemia | Flat T waves, prominent U waves, QT prolongation |
| Hypercalcemia | Short QT |
| Hypocalcemia | Long QT |
π£ Arrhythmias
| Arrhythmia | ECG Pattern |
|---|
| Sinus tachycardia | Regular, rate >100, normal P + QRS |
| AF (Atrial Fibrillation) | Irregularly irregular, no P waves, chaotic baseline |
| Atrial Flutter | Sawtooth P waves at ~300 bpm, 2:1 or 3:1 block |
| SVT | Regular narrow complex tachycardia, P waves may be hidden |
| VT | Wide complex tachycardia, no preceding P waves, rate 100β250 |
| VF | Chaotic, no recognizable complexes β cardiac arrest |
PART 7: Quick Memory Summary
SA node fires β P wave (atria depolarize)
β
AV node delay β PR interval
β
Bundle of His β Bundle branches β Purkinje β QRS (ventricles depolarize)
β
Ventricles contract
β
Ventricles repolarize β T wave
What to Study Next
Now that you have the framework, I'd suggest going deeper in this order:
- Arrhythmias β AF, SVT, VT (most clinically tested)
- MI localization β which leads, which artery
- Bundle branch blocks β very common in wards
- Axis calculation β often asked in exams
Want me to go deep on any of these? I can quiz you, walk through example ECGs, or explain any section in more detail.
Sources: Guyton and Hall Textbook of Medical Physiology | Ganong's Review of Medical Physiology (26th ed.) | Harrison's Principles of Internal Medicine (22nd ed.) | Goldman-Cecil MedicineThat's the full picture β from why an ECG tracing looks the way it does at the cellular level, all the way to recognizing MI, heart blocks, and arrhythmias.
A few tips for making it stick:
- Draw the PQRST wave yourself a few times and label each part β kinesthetic memory helps a lot
- Practice with real ECGs β once you know the pattern, recognition becomes fast
- The 7-step method is your safety net β never skip steps, even when the answer seems obvious
Let me know which section you'd like to explore further, or if you want me to quiz you on what you've just read! π©Ί