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Sprain Management
A sprain is a ligamentous injury caused by a force that stretches or tears a ligament. The ankle is the most commonly affected joint (lateral > medial), followed by the knee and wrist.
Classification (Grading)
| Grade | Pathology | Clinical Features | Weight-Bearing |
|---|
| I | Microscopic tearing; no complete fiber disruption | Minimal tenderness, small/no effusion | Tolerated immediately or within 24 hrs |
| II | Partial (incomplete) tear of some ligament fibers | Moderate tenderness, hematoma, small-moderate effusion | Unable to bear weight for >24 hrs |
| III | Complete tear of all ligament fibers | Significant tenderness, hematoma, large effusion; positive anterior drawer + talar tilt | Unable to bear weight; positive stress tests |
Joint stability - not just grade - is the primary determinant of the treatment plan. - Rosen's Emergency Medicine, p.741
Acute (Initial) Management: PRICE Protocol
PRICE = Protection, Rest, Ice, Compression, Elevation
Apply within the first 24-72 hours of injury:
- Protection - avoid re-injury; splint or brace as needed
- Rest - reduce loading on the injured ligament
- Ice - apply for 15-20 min every 1-2 hours to limit swelling and pain
- Compression - elastic/compression bandage; lace-up support is most effective for short-term edema reduction
- Elevation - raise the limb above the level of the heart
A lace-up ankle splint is more effective in short-term edema reduction than semirigid support, elastic bandaging, or taping alone. - Rosen's Emergency Medicine
Grade-Specific Management
Grade I
- PRICE protocol
- Weight-bearing as tolerated
- ROM (range of motion), proprioceptive, and functional exercises as tolerated
- Compression bandage or taping
Grade II
- PRICE protocol
- Air cast or lace-up brace (immobilization)
- Crutches for a few days if needed
- ROM + proprioceptive + functional exercises when tolerated
- A lace-up brace combined with elastic wrapping gives earlier return to function than either alone
Grade III
- PRICE protocol
- Lace-up support or air cast (permits some motion - preferred over rigid cast)
- Crutches until the patient can bear weight without significant pain (varies from a few days to 2-3 weeks)
- Delayed ROM, proprioceptive, and functional exercises
- Prolonged rehabilitation phase
- Surgery is rarely needed initially; delayed operative repair (even years later) yields results equivalent to primary repair
Functional Rehabilitation: 3 Phases
Current evidence favors early functional treatment over prolonged immobilization. Patients return to mobility 4.6-7.1 days sooner with functional treatment vs. immobilization. - Tintinalli's Emergency Medicine
- Phase 1 (0-24 hrs): PRICE protocol - pain/swelling control
- Phase 2 (48-72 hrs onward): Begin active range-of-motion and strengthening exercises
- Phase 3: Endurance training, sport-specific training, and proprioception/balance training
Analgesia
- NSAIDs (e.g., ibuprofen, naproxen) - first-line for pain and inflammation
- Acetaminophen - alternative or adjunct
- Short course of oral opioids (2-3 days) - only if pain is severe; generally not routine
- Corticosteroid injections are not indicated in acute ankle sprain management
Ottawa Ankle Rules (When to X-Ray)
Before treating conservatively, rule out fracture. Radiography is indicated if:
- Bone tenderness at the posterior edge/tip of the lateral or medial malleolus
- Bone tenderness at the base of the 5th metatarsal (navicular for foot rules)
- Inability to bear weight immediately and in the ED (4 steps)
Also consider imaging the full fibula if deltoid tenderness is present to exclude a Maisonneuve fracture.
Differential Diagnoses to Exclude
Always consider when "ankle sprain" is suspected:
- Fracture of the lateral process of talus or base of 5th metatarsal
- Osteochondral lesion of the talar dome
- Peroneal tendon dislocation
- Syndesmotic ("high ankle") sprain
- Maisonneuve fracture (proximal fibula)
Return to Activity
| Grade | Expected Recovery |
|---|
| I | 1-2 weeks |
| II | 2-4 weeks |
| III | 4-8+ weeks; sometimes months |
Patients not returning to normal activity within the expected window should be re-evaluated with advanced imaging (MRI) for osteochondral lesions, syndesmotic injury, or occult fracture.
Special Situations
- High ankle sprain (syndesmotic injury): More serious than lateral sprain; occurs with hyperdorsiflexion + external rotation; significantly prolongs recovery. - Campbell's Operative Orthopaedics
- Medial deltoid sprain: Rare in isolation (<5%); usually associated with lateral malleolar fracture
- Severe acute sprain: A below-knee cast or Aircast produces faster recovery than a tubular bandage alone, though outcomes are equal at 9 months. - Goldman-Cecil Medicine
- Hand/wrist sprains (MCP ligaments): Grade I and II treated nonoperatively with splinting; Grade III UCL tear in the thumb is usually treated surgically (Stener lesion risk). - Rockwood & Green's Fractures
Sources: Rosen's Emergency Medicine 9e | Tintinalli's Emergency Medicine | Goldman-Cecil Medicine | Rockwood & Green's Fractures in Adults 10e | Campbell's Operative Orthopaedics 15e