what subjects are included in plab 1

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PLAB 1 exam subjects topics included 2025

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PLAB 1 subjects topics syllabus

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GMC PLAB 1 blueprint subjects clinical areas official

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PLAB 1 subjects clinical areas blueprint topics

Here's a comprehensive breakdown of all subjects covered in PLAB 1 (now aligned with the UKMLA Applied Knowledge Test / AKT):

PLAB 1 — Subjects & Clinical Areas

Core Clinical Specialties

SubjectKey Topics
MedicineCardiology, respiratory, gastroenterology, nephrology, neurology, endocrinology, rheumatology, dermatology, infectious diseases, haematology
SurgeryGeneral surgery, orthopaedics, urology, vascular surgery, surgical emergencies
PaediatricsChild development, paediatric emergencies, neonatal conditions, common childhood illnesses
Obstetrics & GynaecologyAntenatal/postnatal care, labour, gynaecological conditions, contraception, fertility
PsychiatryMental health disorders, psychopharmacology, Mental Health Act, suicide/self-harm
Emergency MedicineAcute presentations, resuscitation, ABCDE approach, trauma

Applied & Professional Knowledge Areas

SubjectDetails
Clinical Pharmacology & TherapeuticsDrug prescribing, interactions, adverse effects, pain management
Medical Ethics & LawConsent, capacity, confidentiality, end-of-life care, GMC Good Medical Practice
Microbiology & Infection ControlAntibiotics, infection prevention, sepsis management
Clinical ImagingSelecting appropriate investigations, interpreting common findings
Laboratory HaematologyBlood tests, transfusion medicine
Clinical BiochemistryInterpreting biochemical results, chemical pathology
Genetics & GenomicsPrinciples relevant to clinical practice
HistopathologyIncluding cytology basics
Human Factors & Quality ImprovementPatient safety, audit, clinical governance
Allergy & ImmunologyIncluding clinical physiology and pathology
Biomedical SciencesAnatomy, physiology, pathology, science of ageing

Cross-Cutting Themes

  • Primary care — long-term condition management (diabetes, hypertension, COPD, etc.)
  • Patient safety — prescribing errors, duty of candour
  • Public health & epidemiology — screening, population health
  • Communication & professionalism — GMC standards

Exam Format (Quick Reference)

  • 180 SBA (Single Best Answer) MCQs — 3 hours
  • Questions based on clinical scenarios, not pure fact recall
  • Aligned to NICE guidelines and UK best practice
  • Standard equivalent to a UK Foundation Year 2 (FY2) doctor
  • Held 4 times a year by the GMC

How to Prepare

The GMC directs candidates to the MLA Content Map as the official blueprint — it lists every topic area examined. Standard resources include:
  • Oxford Handbook of Clinical Medicine
  • NICE guidelines
  • Passmedicine / Plabkeys / Pastest question banks
  • BNF (British National Formulary) for pharmacology
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