Yes, clonazepam can reduce tetanus-related spasms because it is a benzodiazepine, but it is not usually the standard first-choice agent in acute tetanus. Guidelines and emergency medicine texts most commonly use diazepam or midazolam, with ICU monitoring, because severe tetanus may cause sudden laryngospasm and respiratory failure. Tetanus management review

Do not give clonazepam at home or use it as the only treatment. Suspected tetanus is a medical emergency requiring urgent hospital care for airway support, spasm control, wound cleaning, antibiotics, tetanus immune globulin, and vaccination.

If the person has jaw stiffness, difficulty swallowing, painful spasms, breathing difficulty, or a recent contaminated wound, seek emergency care now.