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Here is the complete unit-wise compilation of every question from all 21 question papers (April 2015 - July 2025) for First BNYS - Paper IV: Human Physiology II (Q.P. Code: 821506).

FIRST BNYS - HUMAN PHYSIOLOGY II (821506)

COMPLETE UNIT-WISE QUESTION BANK (2015–2025)


UNIT 1: MUSCLE PHYSIOLOGY

Essay Questions

  • List the various changes taking place during muscular contraction. Write the properties of nerve fibres. (Apr 2016, Oct 2021)
  • Explain the different parts and functions of the cerebellum. Write note on cerebellar lesions. (May 2017, Mar 2021)
  • Write about the types, pathways, and physiology of pain. (Oct 2017)
  • Write about Electrical changes during Muscular contraction. (Oct 2022)
  • Write in detail about the electron microscopic structure of skeletal muscle and the molecular mechanism of muscular contraction. (Mar 2023)
  • Mechanism of muscle contraction and add a note on neuromuscular junction. (Sep 2023)
  • Mechanism of Muscle contraction and add a note on Neuro Muscular junction. (Oct 2019)

Write Notes

  • Changes during muscular contraction. (Oct 2017, Jan 2024)
  • Properties of skeletal muscle. (May 2017, May 2019)
  • Excitation-Contraction-Coupling. (Aug 2016)
  • Excitation contraction coupling. (Jan 2025)
  • Neuromuscular Junction. (Apr 2015, Oct 2015, Aug 2016, Mar 2021, Oct 2021, Mar 2023, Sep 2023, Jan 2024, Jan 2025, Jul 2025)
  • Classification and properties of muscle / Classification and properties of nerve fibers. (Oct 2019, Jul 2025)
  • Properties of Smooth muscle. (May 2022)
  • Note on structure of Skeletal muscle / Write in detail about structure of Skeletal muscle. (Mar 2022, Aug 2024)
  • Note on type Contraction of Muscle. (May 2022)
  • Sarcotubular system. (Oct 2022, Jan 2025)
  • Various changes during muscular contraction. (Jan 2025)
  • Myelination of nervous system. (Jul 2025)
  • Receptors and its classification. (Jul 2025)

Short Answers

  • Neuromuscular Junction / Sarcolemma. (Apr 2015)
  • Sarcolemma. (Apr 2015, Jan 2025)
  • Fatigue. (Apr 2015)
  • Spike Potential / Define spike potential. (Apr 2015, Oct 2015, May 2022, Aug 2024)
  • Define Tetanus. (Oct 2015)
  • Neuromuscular Junction. (Oct 2015)
  • Sarcomere. (Aug 2016, Mar 2021, Sep 2023, Jan 2025, Jul 2025)
  • Acetylcholine. (Aug 2016, Mar 2021)
  • Neurotransmitters / Name 4 Neurotransmitters. (Oct 2015, May 2017, May 2019, Oct 2018, Jan 2025)
  • What are muscle proteins? / Name the Muscle Proteins. (Oct 2017, Oct 2022)
  • Isotonic contraction. (May 2018)
  • End plate potential. (May 2018, Aug 2024)
  • Classification of Muscle. (Oct 2018)
  • Properties of Reflex. (Oct 2018)
  • Action Potential. (May 2019, Sep 2023)
  • Saltatory conduction. (May 2019)
  • Power stroke. (May 2019)
  • Types of muscle contraction. (May 2019)
  • Starlings law of Muscle / Define Starling's law of muscle. (Oct 2022, Aug 2024)
  • Rheobase. (Oct 2022, Aug 2024)
  • Name the different stages of Spermatogenesis. (Oct 2022) (see Reproductive section)
  • What are cross bridges? (Jan 2024)
  • What is rigour? (Jan 2024)
  • What is stimulus? (Jan 2024)
  • What is chronaxie? (Jan 2024, Aug 2024)
  • Types of Troponin. (Mar 2023)
  • What is synaptic delay? (Mar 2023)
  • Define proprioreceptors. (Aug 2024)
  • Define Rheobase. (Aug 2024)
  • What is called end plate potential? (Aug 2024)

UNIT 2: NERVOUS SYSTEM - SPINAL CORD & TRACTS

Essay Questions

  • Describe the origin, course termination and functions of pyramidal tract. Write a note on Upper Motor lesions. (Mar 2022)
  • Pyramidal tract its function and lesion. (Jul 2025)

Write Notes

  • Origin and termination of Ascending tracts. (Oct 2015, Mar 2021)
  • Explain Anterior Spinothalamic Tract. (Oct 2015, Mar 2021, May 2022, Aug 2024)
  • List of descending tracts of spinal cord. Write detail about pyramidal tracts. (Aug 2016)
  • Lateral spinothalamic tract. (May 2017)
  • Ventral spinocerebellar tract. (Oct 2017)
  • Brown-Sequard Syndrome. (Oct 2017, Oct 2021, Mar 2022, Aug 2024)
  • Brown Sequard syndrome / Brown sequard syndrome. (Apr 2015, Oct 2015, May 2017 short, Oct 2018, Jan 2025 short, Jul 2025 short)
  • Corticospinal tract. (Oct 2018)
  • Pyramidal tract and its lesion. (May 2019)
  • Upper and lower motor neuron and its lesion. (Oct 2019)
  • Pathway of Pain / Pain pathway. (Oct 2018, May 2019, Oct 2019 ─ under pain, Oct 2022, Jan 2024)
  • Tabes dorsalis. (May 2018)
  • Note on Lower Motor neuron lesions. (Oct 2022)

Short Answers

  • Brown Sequard Syndrome. (Apr 2015, Jul 2025)
  • Syringomyelia. (May 2017, Oct 2019)
  • Babinski sign / Babinski's sign. (Apr 2016, Oct 2021, Oct 2022, Jan 2024)
  • Clonus. (Mar 2022)
  • What is Somatic pain? (Mar 2022)
  • Lumbar puncture. (Oct 2022)
  • Define Brown sequard syndrome. (Jan 2025)

UNIT 3: NERVOUS SYSTEM - BRAIN (CEREBRUM, CEREBELLUM, BASAL GANGLIA, HYPOTHALAMUS, THALAMUS)

Essay Questions

  • Name the hypothalamic nuclei, explain the functions and lesions of hypothalamus. (May 2018)
  • Explain in detail about Limbic System. Enumerate the functional anatomy, connections and functions. (May 2022)
  • Explain in detail about physiology of reticular formation and add a note on EEG. (Mar 2023)
  • Explain in detail about hypothalamo-hypophyseal axis. (Jan 2025)

Write Notes

  • Functions of thalamus / Functions of Thalamus. (Apr 2015, Oct 2015, Mar 2021, Mar 2023, Jan 2025, Jul 2025)
  • Extra Pyramidal Tract. (Apr 2015)
  • Physiology of Sleep. (Apr 2015, Oct 2015, May 2017, Aug 2016, May 2019, Oct 2019, Mar 2021, Mar 2023, Sep 2023, Jul 2025)
  • Reticular formation of brain / Reticular formation. (Oct 2018, May 2017)
  • Motor areas of cerebral cortex. (May 2018)
  • Memory and its classification. (Oct 2018, Jan 2025)
  • Body temperature and its regulation. (May 2019)
  • Function and lesion of Hypothalamus. (May 2019, Oct 2019, Jan 2024, Sep 2023, Jul 2025)
  • Function and lesion of Basal Ganglion / Basal ganglia. (May 2019, Aug 2024, May 2017, Jul 2025 male sex hormones in its place - no, basal ganglia separate)
  • Basal ganglia. (May 2017, May 2019, May 2022, Aug 2024)
  • Functions of Frontal lobe. (Oct 2022, Jan 2024)
  • Smell pathway / Olfactory pathway. (May 2019, Oct 2022)
  • Neuroglial cells / Define neuroglia / Astrocytes. (May 2018, May 2019, Mar 2022)
  • Sympathetic nervous system. (Oct 2018)

Short Answers

  • Proprioceptors. (May 2017)
  • Satiety center / What is Satiety centre? (May 2017, Mar 2022)
  • Broca's area / Define broca's area. (Oct 2017, Aug 2024)
  • Motion sickness. (Oct 2017)
  • Chorean. (May 2018)
  • Petit mal epilepsy. (May 2018)
  • What is Anosognosia? (Aug 2016, Mar 2021, Jan 2025)
  • Electro encephalogram / Waves of EEG. (Oct 2019, Jul 2025)
  • Name the sleep disorders. (Mar 2022)
  • What is Stereognosis? (May 2019)
  • What is Satiety centre? (Mar 2022)
  • Narcolepsy / Define narcolepsy. (Oct 2017, Aug 2024)
  • Types of sleep. (May 2017, Jan 2025)
  • Hypothalamus-hypophyseal system. (May 2019)
  • Function of Cerebral cortex. (Oct 2019)
  • Lesion of cerebellum. (Oct 2019)
  • Schwann cells. (Mar 2023, Jan 2024)

UNIT 4: SPECIAL SENSES - VISION

Essay Questions

  • Draw and explain visual pathway. Explain the effects of lesions at different levels of the visual pathway. (Aug 2016, Aug 2024)
  • Describe in detail the photochemical mechanism of Vision and mechanism of dark adaptation. (Mar 2022)

Write Notes

  • Visual Pathway / course of the visual pathway. (Apr 2015, Apr 2016, Oct 2021)
  • Errors of Refraction / Refractive errors. (Apr 2015, May 2017, Oct 2019, May 2022, Sep 2023)
  • Define Accommodation. Write detail about accommodation reflex and its Pathway. (Apr 2016, Oct 2021, Aug 2024)
  • Colour blindness and test for colour blindness. (Oct 2018, Sep 2023)
  • Colour blindness. (May 2022)
  • Note on Colour blindness. (May 2022)
  • Define adaptation in Eye. (Oct 2022)

Short Answers

  • Errors of Refraction. (Apr 2015)
  • Protanopia. (Apr 2015)
  • Draw a neat labelled diagram of the visual pathway. (Oct 2015)
  • What is 'blind spot' / What is Blind spot. (Oct 2015, Mar 2022, Aug 2024)
  • Dichromatism. (Apr 2016, Oct 2017, Oct 2021, Sep 2023, Jan 2024)
  • Nystagmus. (Aug 2016, Mar 2021, May 2017, Mar 2023, Sep 2023)
  • Glaucoma. (Aug 2016, Mar 2021, Mar 2023, Jan 2025)
  • Accommodation reflex. (Oct 2017)
  • Field of vision. (Oct 2017)
  • Optic chiasm / Optic chiasma. (Apr 2016, May 2018, Oct 2021)
  • Cataract. (May 2018)
  • Colour blindness. (Oct 2019)
  • Light adaptation. (Oct 2019)
  • What is presbyopia? (Mar 2022)
  • Vitreous humor. (Oct 2022)
  • Exophthalmos. (Oct 2022)
  • What is Trichromatism? (Mar 2023)
  • Functions of rods and cones / Functions of rods and cons. (Apr 2016, Oct 2021, Sep 2023)
  • Hypermetropia. (Jul 2025)
  • Circulation of tears. (Oct 2019)
  • Structure of Eye. (Mar 2023 - write notes)

UNIT 5: SPECIAL SENSES - HEARING & VESTIBULAR

Essay Questions

  • Explain in detail about the mechanism of hearing and add a note on hearing tests. (Oct 2015, Mar 2021)
  • Mechanism of Hearing. (May 2018)

Write Notes

  • Tests for hearing / Test of Hearing / Theories of hearing. (Aug 2016, Mar 2022, Oct 2021, Jan 2024, Sep 2023)
  • Auditory pathway. (Mar 2023)
  • Mechanism of Hearing / Explain the Mechanism of Hearing. (Oct 2018, Oct 2019, Oct 2022, Jan 2025, Jul 2025)
  • Functions of vestibular apparatus / Functions of Inner Ear. (Apr 2015, May 2018, Aug 2024)
  • Functions of Middle ear. (Mar 2022)

Short Answers

  • Name the auditory ossicles. (Oct 2015)
  • What is ageusia? (Oct 2015)
  • Rennie's test / Renne's test. (Oct 2017)
  • Audiometry / Explain audiometry. (Apr 2016, Oct 2021, Sep 2023)
  • Type of Deafness. (May 2022)
  • What is chronaxie? (Mar 2023)
  • Taste buds. (Jul 2025)

UNIT 6: SPECIAL SENSES - TASTE & SMELL

Write Notes

  • Pathway for taste / Note on taste pathway / Taste pathway. (Oct 2017, Mar 2022, Aug 2024)
  • Olfactory pathway / Smell pathway. (May 2019, Oct 2022)

Short Answers

  • What is ageusia? (Oct 2015)
  • Taste buds. (Jul 2025)

UNIT 7: CEREBROSPINAL FLUID & REFLEXES

Essay Questions

  • Methods of collection of clinical significance of Cerebro Spinal fluid. (Jan 2024)

Write Notes

  • Cerebrospinal Fluid / Functions of Cerebro Spinal Fluid / CSF. (Apr 2015, Oct 2015, Aug 2016, Mar 2021, May 2022, Mar 2022, Jan 2025, Jul 2025)
  • Cerebro spinal fluid its formation, circulation and function. (Oct 2019)
  • Draw the components of reflex Arc / Reflex Arc. (Oct 2015, Mar 2021, Sep 2023, Jan 2024)
  • Properties of Reflexes. (Mar 2022)
  • Draw the components of reflex Arc and explain. (Jan 2024)

Short Answers

  • Reflex Arc. (Apr 2015, Oct 2019)
  • Properties of Reflex. (Oct 2018)
  • Choroid plexus. (May 2022)
  • Stretch reflex. (Mar 2023)
  • Law of projection. (Mar 2023)

UNIT 8: NERVE PHYSIOLOGY & SYNAPSE

Write Notes

  • Synapse and its function. (Oct 2017, Oct 2018, May 2019, Mar 2022)
  • Mode and action of steroid hormones. (Oct 2017)
  • Mode and action of protein hormone. (May 2018)
  • Mechanism of hormones / Mechanism of actions of hormones on Target cells. (May 2018, Oct 2022)
  • Classification and properties of nerve fibers. (Oct 2019)
  • Note on classification of Synapse. (Mar 2022)
  • Neuromuscular junction. (throughout - see Unit 1)

Short Answers

  • Neurotransmitters / Name 4 Neurotransmitters. (Oct 2015, May 2017, Oct 2018)
  • Kinins. (Aug 2016, Mar 2021)
  • Synapse. (May 2019)
  • Neurons. (Oct 2018)
  • What are Astrocytes? (Mar 2022)
  • What is synaptic delay? (Mar 2023)
  • Schwann cells. (Mar 2023, Jan 2024)

UNIT 9: ENDOCRINOLOGY - THYROID & PARATHYROID

Essay Questions

  • Explain the functions and regulation of Thyroid Hormone. (Apr 2015)
  • Describe the synthesis, storage, functions and regulation of secretion of thyroid hormone. (Apr 2016, Oct 2021)
  • Describe the synthesis, secretion, storage, release, transport, functions and regulation of thyroid hormones. (May 2017)
  • Enlist the hormones secreted by the thyroid gland. Explain the functions and regulations of its hormones. (May 2019)
  • Explain the functions, storage, synthesis, secretion and regulation of thyroid hormone. (Sep 2023)
  • Explain the functions, storage, synthesis, secretion and regulation of Parathyroid. (Jan 2025)

Write Notes

  • Actions of calcitonin and regulation of calcitonin secretion. (Apr 2016, Oct 2021)
  • Stages in synthesis of thyroid hormone. (May 2018)
  • Regulation of blood calcium level. (Oct 2017)
  • Actions of Parathormone / Functions of Parathormone. (Mar 2023, May 2022)
  • Function and applied physiology of thyroid hormones. (Jul 2025)

Short Answers

  • Dwarfism / What is Dwarfism. (Aug 2016, Oct 2017, Mar 2021, Oct 2022, Jan 2025)
  • Graves disease / What is gravis disease. (Aug 2016, Mar 2021, Sep 2023)
  • Coupling reaction of thyroid gland / coupling reactions of thyroid gland. (May 2018, Aug 2024)
  • Osteoporosis. (Apr 2016, Oct 2021)
  • Difference between cretinism and dwarfism. (Mar 2022)
  • What is Goitre? (May 2022)
  • Exophthalmos. (Oct 2022)
  • Acromegaly. (Oct 2022, Jul 2025)

UNIT 10: ENDOCRINOLOGY - PITUITARY & GROWTH HORMONE

Essay Questions

  • Explain in detail about hypothalamo-hypophyseal axis. (Jan 2025)

Write Notes

  • Functions of posterior pituitary hormones. (Oct 2017, Oct 2019)
  • Enumerate the hormones secreted by anterior pituitary gland. (Mar 2023)
  • Note on Growth hormone. (Mar 2022, Jan 2024)
  • Function of Antidiuretic hormone. (May 2022)

Short Answers

  • Gigantism. (Apr 2015)
  • Virilism / What is Virilism. (Apr 2015, Mar 2022)
  • Normal sugar level-fasting and postprandial. (Oct 2017)
  • Hypothalamus-hypophyseal system. (May 2019)
  • Hormones secreted by heart. (May 2017)
  • Releasing Hormones of Hypothalamus. (Oct 2018)
  • Acromegaly. (Oct 2022, Jul 2025)
  • Melatonin. (May 2022)
  • Simmond disease. (May 2022)
  • Sheehan Syndrome. (May 2022, Jan 2024)

UNIT 11: ENDOCRINOLOGY - ADRENAL GLAND & PANCREAS

Essay Questions

  • Enlist the hormones secreted by the pancreas. Explain the functions and regulations of insulin. (Oct 2017)
  • Hormones of adrenal gland, its secretion function and lesion. (Oct 2018)
  • Classify the hormones secreted by adrenal cortex. Explain the action and regulation of secretion of cortisol. (May 2022)

Write Notes

  • Functions of Glucocorticoids. (Aug 2016)
  • Functions of beta cells of Pancreas. (Oct 2015, Mar 2021)
  • Endocrine function of Pancreas. (May 2019)
  • Renin Angiotensin Mechanism. (May 2019)
  • Cushing Syndrome. (Oct 2018)
  • Note on actions of adrenaline and noradrenaline. (Mar 2022)
  • Difference between actions of Adrenalin and Noradrenalin. (Oct 2022)

Short Answers

  • Normal sugar level-fasting and postprandial. (Oct 2017)
  • Secretion of adrenal medulla. (May 2018)
  • Name the Hormones of Adrenal medulla. (May 2022, Jan 2024)
  • Function of Prostaglandin. (May 2019)
  • What is Dwarfism? (Oct 2022)

UNIT 12: REPRODUCTIVE PHYSIOLOGY - MALE

Essay Questions

  • Write in detail about function of testes and spermatogenesis and composition of semen. (Jan 2024)
  • Explain in detail about Spermatogenesis stages. Add a note on semen and its composition. (May 2019)

Write Notes

  • Explain about Spermatogenesis. (Aug 2016)
  • Functions of testis / Functions of testes. (Oct 2015, Oct 2017, Mar 2021, Sep 2023)
  • Physiology of reproduction. (May 2018)
  • Functions of testosterone in adult life. (Apr 2016, Oct 2021, Aug 2024)
  • Composition of Semen. (May 2018, May 2019, Mar 2023)
  • Explain about the composition of semen. (Aug 2024, Jul 2025)
  • Male sex hormones and its function. (Jul 2025)
  • Explain functions of spermatogenesis. (Mar 2021)

Short Answers

  • Cryptorchidism. (Apr 2015, Aug 2016, Mar 2021, Sep 2023)
  • Vasectomy. (Aug 2016, Mar 2021, Jan 2025)
  • Properties of Semen. (Apr 2015)
  • Oligozoospermia. (Apr 2016, Oct 2021)
  • Functions of seminiferous tubules. (May 2018)
  • Spermatogenesis. (Oct 2018)
  • Testosterone. (Oct 2018)
  • Gonads. (May 2019)
  • Fertilization / Define fertilization. (Oct 2018, Aug 2024)
  • Name the different stages of Spermatogenesis. (Oct 2022)
  • Composition of semen. (Oct 2021, May 2022, Jan 2025, Jul 2025)

UNIT 13: REPRODUCTIVE PHYSIOLOGY - FEMALE

Essay Questions

  • Define Menstrual Cycle. Explain the Ovarian changes during the Menstrual cycle. (Apr 2015)
  • Menstrual cycle and its changes in the ovaries and uterus and add a note on physiology of pregnancy. (Oct 2015)
  • Describe uterine changes occurring during menstrual cycle. Add a note on hormonal regulation of the menstrual cycle. (Aug 2016)
  • Menstrual Cycle its stages and Hormonal regulation. (Oct 2019)
  • Give an account of Menstrual cycle and explain the hormonal regulations of menstrual cycle. (Oct 2022)
  • Define Menstrual Cycle. Explain the various phases in Menstrual cycle with its hormonal regulation. (Jul 2025)
  • Explain in detail about Ovarian cycle its events and hormonal regulation. (Oct 2018)

Write Notes

  • Regulation and secretion of ovarian hormones. (May 2017)
  • Uterine changes during menstrual cycle. (May 2017)
  • Ovarian changes during menstrual cycle / Ovarian cycle. (Apr 2016, May 2018, Oct 2021, Jan 2024, Sep 2023)
  • Physiology of lactation / Lactation. (Apr 2016, May 2017, Oct 2019, Oct 2021, Jan 2025)
  • Define ovulation. Process and hormonal regulation of ovulation. (Apr 2016, Oct 2021)
  • Development of corpus luteum, functions and fate of corpus luteum. (Apr 2016, Oct 2021)
  • Milk ejection reflex. (Aug 2016, Sep 2023)
  • Female sex hormones / What are the Female sex hormones and their actions. (Oct 2018, May 2022, Aug 2024, Jul 2025)
  • Physiology of lactation. (Oct 2019)
  • Write a note on Oogenesis. (Oct 2022)
  • Process of Ovulation. (Mar 2023)

Short Answers

  • Infertility. (Apr 2016, Oct 2021)
  • Functions of oxytocin / Explain the functions of Oxytocin. (Oct 2015, Apr 2016, May 2017, Oct 2021, Sep 2023, Jan 2025, Jul 2025)
  • Define ovulation. (Oct 2015)
  • Menopause / Define Menopause. (May 2017, May 2022, Mar 2023, Sep 2023, Jul 2025 LH surge)
  • LH surge. (Jul 2025)
  • Test for Ovulation. (Oct 2019)
  • What is parturition? (Jan 2024)
  • Changes takes place during puberty. (Jul 2025)
  • Melatonin. (May 2022)
  • Sheehan Syndrome. (May 2022)

UNIT 14: SYNAPSE, PAIN & GENERAL NEUROPHYSIOLOGY

Essay Questions

  • Explain in detail about the types of synapses and their structure and properties of neurotransmitters. (Aug 2024)

Write Notes

  • Synapse and its function. (Oct 2017, Oct 2018)
  • Pain pathway / Pathway of Pain. (Oct 2018, May 2019, Oct 2022, Jan 2024)
  • Note on classification of Synapse. (Mar 2022)
  • Neuroglial cells. (May 2019)

Short Answers

  • Benefits of pain sensation. (Apr 2016, Oct 2021)
  • Synapse. (May 2019)
  • What is Somatic pain? (Mar 2022)

MOST REPEATED TOPICS (Exam Priority)

TopicTimes Asked
Menstrual Cycle (Essay)7 times
Neuromuscular Junction (Notes)10+ times
Thyroid Hormone (Essay/Notes)6 times
Physiology of Sleep10+ times
Mechanism of Hearing8 times
CSF (composition, functions)8 times
Visual Pathway6 times
Brown-Sequard Syndrome7 times
Muscle Contraction / Changes8 times
Functions of Thalamus7 times
Errors of Refraction6 times
Spermatogenesis / Testis7 times
Colour Blindness5 times
Pyramidal Tract5 times
Basal Ganglia5 times
Neuromuscular Junction (Short)repeated
Sarcomere5 times
Nystagmus5 times
Dichromatism5 times
Oxytocin functions7 times
Hypothalamus (function/lesion)6 times
Composition of Semen7 times
Reflex Arc5 times

Total Papers Covered: 21 (April 2015 to July 2025) Subject: First BNYS - Paper IV Human Physiology II (Q.P. Code 821506) University: The Tamil Nadu Dr. M.G.R. Medical University
Every single question from every paper is included above, organized into 14 units. The "Most Repeated Topics" table at the end shows which topics to prioritize for maximum exam score.
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