from reportlab.lib.pagesizes import letter
from reportlab.pdfgen import canvas
from reportlab.lib import colors
from reportlab.pdfbase.pdfmetrics import stringWidth
from reportlab.lib.units import inch
from pypdf import PdfReader

OUT = '/tmp/workspace/acs-timeline-pdf/output/ACS_Timeline_Quick_Reference.pdf'
W, H = letter

NAVY = colors.HexColor('#102A43')
BLUE = colors.HexColor('#2563A8')
PALE_BLUE = colors.HexColor('#EAF3FA')
RED = colors.HexColor('#B42318')
PALE_RED = colors.HexColor('#FDECEC')
GREEN = colors.HexColor('#19734A')
PALE_GREEN = colors.HexColor('#EAF7EF')
AMBER = colors.HexColor('#9A6700')
PALE_AMBER = colors.HexColor('#FFF7E6')
GRAY = colors.HexColor('#52606D')
LINE = colors.HexColor('#CBD5E1')
WHITE = colors.white

c = canvas.Canvas(OUT, pagesize=letter)
c.setTitle('ACS Timeline Quick Reference')
c.setAuthor('Orris')

M = 30

def rect(x,y,w,h,fill,stroke=None, radius=0):
    c.setFillColor(fill)
    c.setStrokeColor(stroke or fill)
    if radius:
        c.roundRect(x,y,w,h,radius,fill=1,stroke=1 if stroke else 0)
    else:
        c.rect(x,y,w,h,fill=1,stroke=1 if stroke else 0)

def txt(x,y,text,size=9,color=NAVY,font='Helvetica', maxw=None, leading=None):
    c.setFillColor(color); c.setFont(font,size)
    if maxw is None:
        c.drawString(x,y,text); return y-size
    words=text.split(); lines=[]; line=''
    for word in words:
        test=(line+' '+word).strip()
        if stringWidth(test,font,size) <= maxw: line=test
        else: lines.append(line); line=word
    if line: lines.append(line)
    ld=leading or size*1.25
    for i,ln in enumerate(lines): c.drawString(x,y-i*ld,ln)
    return y-len(lines)*ld

def bold(x,y,text,size=9,color=NAVY):
    return txt(x,y,text,size,color,'Helvetica-Bold')

def pill(x,y,label,bg,fg):
    width=stringWidth(label,'Helvetica-Bold',7.2)+12
    rect(x,y,width,16,bg,radius=8)
    c.setFillColor(fg); c.setFont('Helvetica-Bold',7.2); c.drawCentredString(x+width/2,y+4.5,label)
    return width

def bullet(x,y,text,width,size=8.2,color=NAVY):
    c.setFillColor(BLUE); c.circle(x+3,y+2.6,1.6,fill=1,stroke=0)
    return txt(x+10,y,text,size,color,'Helvetica',width-10,10.2)

# header
rect(0,H-88,W,88,NAVY)
c.setFillColor(WHITE); c.setFont('Helvetica-Bold',22); c.drawString(M,H-43,'ACUTE CORONARY SYNDROME')
c.setFont('Helvetica-Bold',11); c.setFillColor(colors.HexColor('#B9E3FF')); c.drawString(M,H-62,'TIMELINE QUICK REFERENCE  |  Adult suspected ACS')
c.setFont('Helvetica',7.5); c.setFillColor(colors.HexColor('#D9E2EC')); c.drawRightString(W-M,H-62,'2025 ACC/AHA and 2023 ESC guidance')

# immediate action bar
Y=H-112
rect(M,Y-36,W-2*M,36,PALE_BLUE,LINE,5)
bold(M+12,Y-14,'0-10 MIN',10,BLUE)
txt(M+82,Y-14,'Monitor, obtain IV access, focused assessment, and acquire/interpret a 12-lead ECG.',9,NAVY)
txt(M+82,Y-27,'Give aspirin promptly when appropriate. Do not delay STEMI reperfusion for troponin.',8,GRAY)

# diagnostic strip
Y-=56
bold(M,Y,'1. CLASSIFY THE PRESENTATION',11,NAVY)
rect(M,Y-67,174,54,PALE_RED,LINE,5); pill(M+10,Y-31,'STEMI / equivalent',PALE_RED,RED)
txt(M+10,Y-47,'Persistent ST elevation or ischemic',8,NAVY,154)
txt(M+10,Y-58,'equivalent: activate reperfusion.',8,NAVY,154)
rect(M+187,Y-67,174,54,PALE_AMBER,LINE,5); pill(M+197,Y-31,'NSTE-ACS',PALE_AMBER,AMBER)
txt(M+197,Y-47,'No persistent ST elevation:',8,NAVY,154)
txt(M+197,Y-58,'serial hs-troponin + risk stratify.',8,NAVY,154)
rect(M+374,Y-67,174,54,PALE_GREEN,LINE,5); pill(M+384,Y-31,'ONGOING SUPPORT',PALE_GREEN,GREEN)
txt(M+384,Y-47,'Oxygen only if hypoxemia, distress,',8,NAVY,154)
txt(M+384,Y-58,'or shock. Treat instability at once.',8,NAVY,154)

# STEMI Panel
Y-=91
rect(M,Y-229,267,216,colors.HexColor('#FAFCFE'),LINE,6)
rect(M,Y-41,267,28,RED,RED,6)
c.setFillColor(WHITE); c.setFont('Helvetica-Bold',12); c.drawString(M+12,Y-31,'2. STEMI: REPERFUSION PATHWAY')
y=Y-59
bold(M+13,y,'Symptom onset <12 h',9,RED); y-=17
y=bullet(M+13,y,'Primary PCI is preferred when first-medical-contact to device time is 120 min or less.',240); y-=5
y=bullet(M+13,y,'If expected PCI delay is >120 min and no contraindication: give fibrinolysis promptly, then transfer immediately to a PCI centre.',240); y-=5
rect(M+13,y-31,239,29,PALE_RED,None,4)
bold(M+22,y-13,'Fibrinolysis target: needle ≤30 min',8.8,RED)
txt(M+22,y-24,'from hospital arrival / first contact pathway.',7.7,GRAY)
y-=48
y=bullet(M+13,y,'Suspected failed fibrinolysis: immediate rescue PCI.',240); y-=5
y=bullet(M+13,y,'Successful fibrinolysis: angiography with planned PCI at 2-24 h.',240); y-=5
y=bullet(M+13,y,'Ongoing ischemia, shock, acute HF, or electrical instability: urgent angiography/PCI regardless of delay.',240)

# NSTEMI panel
rect(M+282,Y-229,300,216,colors.HexColor('#FAFCFE'),LINE,6)
rect(M+282,Y-41,300,28,AMBER,AMBER,6)
c.setFillColor(WHITE); c.setFont('Helvetica-Bold',12); c.drawString(M+294,Y-31,'3. NSTE-ACS: TIMING OF ANGIOGRAPHY')
y=Y-60
# rows
rows=[
 ('IMMEDIATE  <2 h', 'Very high risk: shock/hemodynamic instability, refractory pain, life-threatening arrhythmia, acute HF, mechanical complication, recurrent dynamic ST changes.', PALE_RED, RED),
 ('EARLY  <24 h', 'High risk: confirmed NSTEMI, dynamic ST-T changes, transient ST elevation, or GRACE >140.', PALE_AMBER, AMBER),
 ('IN-HOSPITAL / SELECTIVE', 'Intermediate risk: invasive assessment during admission. Low-risk or uncertain ACS: selective testing/observation pathway.', PALE_GREEN, GREEN),
]
for label,body,bg,fg in rows:
    rect(M+294,y-49,276,44,bg,None,4)
    bold(M+303,y-18,label,8.4,fg)
    txt(M+303,y-30,body,7.5,NAVY,255,9)
    y-=54
bold(M+294,Y-222,'Do NOT use fibrinolysis for NSTEMI or unstable angina.',8.2,RED)

# medication and disposition
Y-=251
bold(M,Y,'4. EARLY MEDICAL THERAPY AND DISCHARGE CHECKPOINTS',11,NAVY)
rect(M,Y-82,552,68,PALE_BLUE,LINE,5)
# 3 columns
bold(M+12,Y-32,'NOW',8.8,BLUE)
txt(M+12,Y-45,'Aspirin, P2Y12 inhibitor and anticoagulation as indicated. Nitrates if suitable. High-intensity statin early.',7.7,NAVY,164,9.5)
bold(M+194,Y-32,'BEFORE DISCHARGE',8.8,BLUE)
txt(M+194,Y-45,'DAPT plan, secondary prevention, cardiac rehabilitation, smoking cessation, and follow-up.',7.7,NAVY,164,9.5)
bold(M+376,Y-32,'4-8 WEEKS',8.8,BLUE)
txt(M+376,Y-45,'Check fasting lipid panel after starting or changing lipid-lowering therapy.',7.7,NAVY,164,9.5)

# footer caution + sources
Y=42
rect(M,Y,552,30,colors.HexColor('#FFF5F5'),colors.HexColor('#F8B4B4'),5)
bold(M+10,Y+17,'SAFETY:',8.2,RED)
txt(M+58,Y+17,'Use local protocols and senior cardiology/emergency input. This is an educational quick-reference, not a standalone order set.',7.4,NAVY)
txt(M,Y-12,'Sources: 2025 ACC/AHA/ACEP/NAEMSP/SCAI ACS Guideline (Circulation, PMID 40014670); 2023 ESC ACS Guideline.',6.8,GRAY)
txt(M,Y-22,'Key targets: ECG ≤10 min; PCI decision threshold FMC-to-device 120 min; fibrinolysis target ≤30 min; NSTE-ACS immediate <2 h / early <24 h.',6.8,GRAY)

c.showPage(); c.save()
# Verify one page and extract text
reader=PdfReader(OUT)
assert len(reader.pages)==1, f'Expected one page, got {len(reader.pages)}'
text=reader.pages[0].extract_text()
assert 'ACUTE CORONARY SYNDROME' in text and 'STEMI' in text and 'NSTE-ACS' in text
print(f'Created {OUT} | pages={len(reader.pages)} | text_chars={len(text)}')

Successfully replaced 1 instance(s) of the string in '/tmp/workspace/acs-timeline-pdf/src/create_acs_timeline.py'

Successfully replaced 1 instance(s) of the string in '/tmp/workspace/acs-timeline-pdf/src/create_acs_timeline.py'

Successfully replaced 1 instance(s) of the string in '/tmp/workspace/acs-timeline-pdf/src/create_acs_timeline.py'