Anatomy of eye acc to khurrna

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anatomy of the eye diagram layers fibrous uveal nervous coat

This composite educational graphic illustrates human ocular anatomy and diagnostic imaging. Section A presents a sagittal schematic diagram of the eye, highlighting the three posterior layers: the retina (inner), the choroid (middle vascular layer), and the sclera (outer fibrous layer). A black box indicates the posterior pole region being analyzed. Section B features a Spectral Domain Optical Coherence Tomography (SD-OCT) scan centered on the fovea. The left side of panel B shows a grayscale infrared fundus image with a green horizontal line indicating the scan acquisition path. The right side displays the corresponding cross-sectional OCT B-scan, which provides high-resolution visualization of the retinal architecture, the underlying choroidal layer with its characteristic vascular luminal and stromal spaces, and the interface with the sclera. Labels on the B-scan confirm the stratified arrangement of the retina, choroid, and sclera, making this a foundational resource for understanding posterior segment imaging and choroidal thickness assessment.

This composite educational graphic illustrates human ocular anatomy and diagnostic imaging. Section A presents a sagittal schematic diagram of the eye, highlighting the three posterior layers: the retina (inner), the choroid (middle vascular layer), and the sclera (outer fibrous layer). A black box indicates the posterior pole region being analyzed. Section B features a Spectral Domain Optical Coherence Tomography (SD-OCT) scan centered on the fovea. The left side of panel B shows a grayscale infrared fundus image with a green horizontal line indicating the scan acquisition path. The right side displays the corresponding cross-sectional OCT B-scan, which provides high-resolution visualization of the retinal architecture, the underlying choroidal layer with its characteristic vascular luminal and stromal spaces, and the interface with the sclera. Labels on the B-scan confirm the stratified arrangement of the retina, choroid, and sclera, making this a foundational resource for understanding posterior segment imaging and choroidal thickness assessment.

This medical-botanical schematic illustration depicts a longitudinal cross-section of a barley kernel (Hordeum vulgare), serving as a model for cereal grain anatomy relevant to human nutrition and dietetics. The diagram identifies key structural components involved in nutrient distribution, specifically the localization of anthocyanins and fiber. The anatomical layers are labeled from the periphery to the interior: the outermost fibrous Husk, the thin protective Testa, and the Aleurone layer composed of structured, brick-like cells. The largest central region is the Endosperm, characterized by a grainy, fibrous texture. At the base of the kernel, the embryo-related structures, the Scutellum and the Germ, are clearly demarcated. This diagram is educationally significant for understanding the localization of bioactive compounds like phenolic pigments, which are primarily concentrated in the outer layers (pericarp and aleurone) and are often lost during commercial milling processes.

This medical-botanical schematic illustration depicts a longitudinal cross-section of a barley kernel (Hordeum vulgare), serving as a model for cereal grain anatomy relevant to human nutrition and dietetics. The diagram identifies key structural components involved in nutrient distribution, specifically the localization of anthocyanins and fiber. The anatomical layers are labeled from the periphery to the interior: the outermost fibrous Husk, the thin protective Testa, and the Aleurone layer composed of structured, brick-like cells. The largest central region is the Endosperm, characterized by a grainy, fibrous texture. At the base of the kernel, the embryo-related structures, the Scutellum and the Germ, are clearly demarcated. This diagram is educationally significant for understanding the localization of bioactive compounds like phenolic pigments, which are primarily concentrated in the outer layers (pericarp and aleurone) and are often lost during commercial milling processes.

This composite educational graphic details the neuroanatomical continuity between the eye and the central nervous system. Panel A features a sagittal pathophysiology diagram illustrating the connection from the eyeball to the brain via the optic nerve. It highlights the layers of the eye (sclera, choroid, retina), the vitreum, and the optic foramen. A magnified histological inset shows the optic nerve head, lamina cribrosa, and central retinal vessels. Crucially, the diagram labels the subarachnoid space (SAS), demonstrating its continuity from the intracranial compartment to the orbital optic nerve sheath. Panel B provides clinical correlation with an axial T2-weighted MRI scan, where high-intensity (bright) signal represents cerebrospinal fluid (CSF) within the optic nerve SAS, contrasting against the dark optic nerves extending from the posterior globes. Panel C displays a coronal MRI slice further demonstrating the bilateral symmetry of the optic nerve sheaths. This material is designed to teach the physiological link between intracranial pressure and ocular health, relevant to specialties like ophthalmology, neurology, and radiology.

This composite educational graphic details the neuroanatomical continuity between the eye and the central nervous system. Panel A features a sagittal pathophysiology diagram illustrating the connection from the eyeball to the brain via the optic nerve. It highlights the layers of the eye (sclera, choroid, retina), the vitreum, and the optic foramen. A magnified histological inset shows the optic nerve head, lamina cribrosa, and central retinal vessels. Crucially, the diagram labels the subarachnoid space (SAS), demonstrating its continuity from the intracranial compartment to the orbital optic nerve sheath. Panel B provides clinical correlation with an axial T2-weighted MRI scan, where high-intensity (bright) signal represents cerebrospinal fluid (CSF) within the optic nerve SAS, contrasting against the dark optic nerves extending from the posterior globes. Panel C displays a coronal MRI slice further demonstrating the bilateral symmetry of the optic nerve sheaths. This material is designed to teach the physiological link between intracranial pressure and ocular health, relevant to specialties like ophthalmology, neurology, and radiology.

This educational illustration is an anatomical diagram of the human eye in sagittal cross-section, overlaid with a portrait of Hermann von Helmholtz. The diagram, rendered in red linework, depicts essential ophthalmic structures including the cornea (labeled B), the crystalline lens (labeled A), and the ciliary body (b). Various alphabetical annotations (c, d, e, f, g, h, i, k, m, n) indicate specific histological and anatomical regions, such as the sclera, retina, choroid layers, and the optic nerve exit (d). The lens is shown in its anatomical position behind the anterior chamber and iris. The image serves as a conceptual tribute to physiological optics, bridging the anatomy of vision with the historical figure responsible for major advancements in the field, such as the invention of the ophthalmoscope and the primary treatise on physiological optics. The spatial arrangement emphasizes the internal ocular environment, with the retinal lining and posterior segment framing the central portrait.

This educational illustration is an anatomical diagram of the human eye in sagittal cross-section, overlaid with a portrait of Hermann von Helmholtz. The diagram, rendered in red linework, depicts essential ophthalmic structures including the cornea (labeled B), the crystalline lens (labeled A), and the ciliary body (b). Various alphabetical annotations (c, d, e, f, g, h, i, k, m, n) indicate specific histological and anatomical regions, such as the sclera, retina, choroid layers, and the optic nerve exit (d). The lens is shown in its anatomical position behind the anterior chamber and iris. The image serves as a conceptual tribute to physiological optics, bridging the anatomy of vision with the historical figure responsible for major advancements in the field, such as the invention of the ophthalmoscope and the primary treatise on physiological optics. The spatial arrangement emphasizes the internal ocular environment, with the retinal lining and posterior segment framing the central portrait.

Brightfield light microscopy of a hematoxylin and eosin stained sagittal cross‑section through an ocular globe. The slide displays the layered architecture of the eye, with a prominent circular structure representing the crystalline lens encased by a thin capsule and adjacent zonular fibers. Surrounding tissues reveal the scleral white of the globe and the immediately subjacent uveal tissues, including choroid and pigmented retinal pigment epithelium, transitioning to the multi‑layered neural retina at the inner surface. Nuclei appear dark purple on hematoxylin, while cytoplasm and extracellular matrix stain pink to pale pink, creating distinct optic nerve/retinal nerve fiber layer boundaries peripherally and centrally. The vitreous body appears relatively acellular and eosinophilic, separating the lens from the retina. The optic axis and ciliary body regions may be suggested at the periphery by tubular structures and vascular patterns. Overall, this image demonstrates normal ocular histomorphology suitable for educational reference, anatomical atlas documentation, and pattern recognition training in ophthalmic pathology. Potential clinical applications include teaching ocular anatomy (globe, lens, retina, sclera, choroid), diagnosing cataract or retinal disorders in histological specimens, and serving as a baseline for comparative studies in ocular development and disease. This representation emphasizes laminar organization, including anterior corneal–limbal regions not visible here, posterior retina layers such as ganglion cell layer and inner nuclear layer, and lens substructures—capsule, cortex, and nucleus—facilitating recognition tasks for students and clinicians. High-quality reference for ophthalmology education.

Brightfield light microscopy of a hematoxylin and eosin stained sagittal cross‑section through an ocular globe. The slide displays the layered architecture of the eye, with a prominent circular structure representing the crystalline lens encased by a thin capsule and adjacent zonular fibers. Surrounding tissues reveal the scleral white of the globe and the immediately subjacent uveal tissues, including choroid and pigmented retinal pigment epithelium, transitioning to the multi‑layered neural retina at the inner surface. Nuclei appear dark purple on hematoxylin, while cytoplasm and extracellular matrix stain pink to pale pink, creating distinct optic nerve/retinal nerve fiber layer boundaries peripherally and centrally. The vitreous body appears relatively acellular and eosinophilic, separating the lens from the retina. The optic axis and ciliary body regions may be suggested at the periphery by tubular structures and vascular patterns. Overall, this image demonstrates normal ocular histomorphology suitable for educational reference, anatomical atlas documentation, and pattern recognition training in ophthalmic pathology. Potential clinical applications include teaching ocular anatomy (globe, lens, retina, sclera, choroid), diagnosing cataract or retinal disorders in histological specimens, and serving as a baseline for comparative studies in ocular development and disease. This representation emphasizes laminar organization, including anterior corneal–limbal regions not visible here, posterior retina layers such as ganglion cell layer and inner nuclear layer, and lens substructures—capsule, cortex, and nucleus—facilitating recognition tasks for students and clinicians. High-quality reference for ophthalmology education.

This medical illustration presents an anatomical diagram of a human brain in a mid-sagittal section, featuring the superimposition of the Eye of Horus over key neuroanatomical structures. The underlying anatomy displays the cerebrum with its cortical gyri and sulci, the corpus callosum, the cerebellum showing the arbor vitae pattern, the brainstem, and the diencephalic region. The Eye of Horus is strategically aligned to illustrate perceived correlations between its geometric components and functional brain anatomy: the eyebrow corresponds to the corpus callosum; the pupil is centered over the thalamus and interthalamic adhesion (massa intermedia); the anterior triangular component aligns with the olfactory trigone; and the descending extensions correspond to the pathways for hearing (Brodmann areas 41/42), taste, and the somatosensory tract. The image serves as a comparative conceptual diagram linking ancient symbolic art with functional neuroanatomy, highlighting the central nervous system's sensory processing centers and commissural fibers.

This medical illustration presents an anatomical diagram of a human brain in a mid-sagittal section, featuring the superimposition of the Eye of Horus over key neuroanatomical structures. The underlying anatomy displays the cerebrum with its cortical gyri and sulci, the corpus callosum, the cerebellum showing the arbor vitae pattern, the brainstem, and the diencephalic region. The Eye of Horus is strategically aligned to illustrate perceived correlations between its geometric components and functional brain anatomy: the eyebrow corresponds to the corpus callosum; the pupil is centered over the thalamus and interthalamic adhesion (massa intermedia); the anterior triangular component aligns with the olfactory trigone; and the descending extensions correspond to the pathways for hearing (Brodmann areas 41/42), taste, and the somatosensory tract. The image serves as a comparative conceptual diagram linking ancient symbolic art with functional neuroanatomy, highlighting the central nervous system's sensory processing centers and commissural fibers.

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cross section of eye cornea lens retina choroid sclera diagram

This educational graphic illustrates the anatomical and diagnostic visualization of the posterior segment of the human eye. Section (a) contains three panels: a sagittal cross-sectional diagram of the eye showing the anterior (cornea, lens) and posterior segments; a sample Optical Coherence Tomography (OCT) B-scan identifying the retina (innermost), choroid (middle), and sclera (outermost); and an annotated OCT B-scan specifically delineating the choroid. The annotated scan highlights the choroidal inner boundary (CIB), the choroidal outer boundary (COB) at the choroid-sclera interface, and individual choroidal vessels within the vascular stroma. Section (b) presents a diagnostic flowchart for clinical decision-making, emphasizing 'Quality Assessment' as a mandatory intermediary step between data acquisition and disease screening. This material is designed for ophthalmology education, focusing on retinal imaging, choroidal biomarker quantification (such as thickness and vascularity index), and the importance of image quality in automated diagnostic pipelines for conditions like central serous chorioretinopathy and age-related macular degeneration.

This educational graphic illustrates the anatomical and diagnostic visualization of the posterior segment of the human eye. Section (a) contains three panels: a sagittal cross-sectional diagram of the eye showing the anterior (cornea, lens) and posterior segments; a sample Optical Coherence Tomography (OCT) B-scan identifying the retina (innermost), choroid (middle), and sclera (outermost); and an annotated OCT B-scan specifically delineating the choroid. The annotated scan highlights the choroidal inner boundary (CIB), the choroidal outer boundary (COB) at the choroid-sclera interface, and individual choroidal vessels within the vascular stroma. Section (b) presents a diagnostic flowchart for clinical decision-making, emphasizing 'Quality Assessment' as a mandatory intermediary step between data acquisition and disease screening. This material is designed for ophthalmology education, focusing on retinal imaging, choroidal biomarker quantification (such as thickness and vascularity index), and the importance of image quality in automated diagnostic pipelines for conditions like central serous chorioretinopathy and age-related macular degeneration.

This educational graphic combines an anatomical diagram of the human eye with corresponding ophthalmic imaging modalities. The 'Ocular Anatomy' section features a detailed sagittal cross-section identifying key structures: the cornea, aqueous humor, iris, pupil, biconvex lens, zonule fibers, and ciliary muscle in the anterior segment; and the vitreous humor, retina, fovea, choroid, sclera, and optic nerve in the posterior segment. The 'Image Modalities' section illustrates diagnostic tools used to visualize these structures. A color Fundus Photograph provides a surface view of the retina, optic disc, and vasculature. A 3D Volumetric Optical Coherence Tomography (OCT) scan displays a high-resolution, grayscale cross-sectional view of retinal layers, highlighting tissue stratification. Finally, Optical Coherence Tomography Angiography (OCTA) panels show non-invasive, depth-resolved images of the retinal and choroidal microvasculature. This composite serves as a reference for correlating anatomical landmarks with clinical diagnostic imaging used in the management of retinal diseases such as Age-related Macular Degeneration (AMD).

This educational graphic combines an anatomical diagram of the human eye with corresponding ophthalmic imaging modalities. The 'Ocular Anatomy' section features a detailed sagittal cross-section identifying key structures: the cornea, aqueous humor, iris, pupil, biconvex lens, zonule fibers, and ciliary muscle in the anterior segment; and the vitreous humor, retina, fovea, choroid, sclera, and optic nerve in the posterior segment. The 'Image Modalities' section illustrates diagnostic tools used to visualize these structures. A color Fundus Photograph provides a surface view of the retina, optic disc, and vasculature. A 3D Volumetric Optical Coherence Tomography (OCT) scan displays a high-resolution, grayscale cross-sectional view of retinal layers, highlighting tissue stratification. Finally, Optical Coherence Tomography Angiography (OCTA) panels show non-invasive, depth-resolved images of the retinal and choroidal microvasculature. This composite serves as a reference for correlating anatomical landmarks with clinical diagnostic imaging used in the management of retinal diseases such as Age-related Macular Degeneration (AMD).

This educational illustration is an anatomical diagram of the human eye in sagittal cross-section, overlaid with a portrait of Hermann von Helmholtz. The diagram, rendered in red linework, depicts essential ophthalmic structures including the cornea (labeled B), the crystalline lens (labeled A), and the ciliary body (b). Various alphabetical annotations (c, d, e, f, g, h, i, k, m, n) indicate specific histological and anatomical regions, such as the sclera, retina, choroid layers, and the optic nerve exit (d). The lens is shown in its anatomical position behind the anterior chamber and iris. The image serves as a conceptual tribute to physiological optics, bridging the anatomy of vision with the historical figure responsible for major advancements in the field, such as the invention of the ophthalmoscope and the primary treatise on physiological optics. The spatial arrangement emphasizes the internal ocular environment, with the retinal lining and posterior segment framing the central portrait.

This educational illustration is an anatomical diagram of the human eye in sagittal cross-section, overlaid with a portrait of Hermann von Helmholtz. The diagram, rendered in red linework, depicts essential ophthalmic structures including the cornea (labeled B), the crystalline lens (labeled A), and the ciliary body (b). Various alphabetical annotations (c, d, e, f, g, h, i, k, m, n) indicate specific histological and anatomical regions, such as the sclera, retina, choroid layers, and the optic nerve exit (d). The lens is shown in its anatomical position behind the anterior chamber and iris. The image serves as a conceptual tribute to physiological optics, bridging the anatomy of vision with the historical figure responsible for major advancements in the field, such as the invention of the ophthalmoscope and the primary treatise on physiological optics. The spatial arrangement emphasizes the internal ocular environment, with the retinal lining and posterior segment framing the central portrait.

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The Kanski sections found are clinical chapters, not basic anatomy chapters. Since Khurrana's "Comprehensive Ophthalmology" is not in the library, I have enough information from the Ganong physiology section (which covers the same anatomy) and my own knowledge to give a thorough, well-structured answer aligned with Khurrana's approach. Let me now compose the comprehensive answer based on all sources gathered.

Anatomy of the Eye (as per Khurrana's Comprehensive Ophthalmology)

Note: Khurrana's Comprehensive Ophthalmology is not directly available in our textbook library. The following is presented according to Khurrana's well-known organizational framework, supplemented by Kanski's Clinical Ophthalmology and Ganong's Review of Medical Physiology available in our library.
Anatomy of the Eye - Cross Section
Cross-section of the human eye showing all major structures - Ganong's Review of Medical Physiology

Overview

The eyeball (globe) is a roughly spherical structure, approximately 24 mm in anteroposterior diameter. It sits in the bony orbit surrounded by orbital fat and is moved by six extraocular muscles. The wall of the eyeball is made up of three concentric coats (tunics):
  1. Fibrous coat (outer)
  2. Uveal coat / Vascular coat (middle)
  3. Nervous coat / Retina (inner)
The interior is divided into compartments filled with transparent media.

1. Fibrous Coat (Outer Coat)

A. Sclera (Posterior 5/6)

  • Tough, opaque, white fibrous tissue made of dense collagen bundles
  • Provides structural rigidity and protects intraocular contents
  • Perforated posteriorly by the lamina cribrosa (where optic nerve fibres pass through)
  • Externally, is continuous with the dural sheath of the optic nerve
  • Anteriorly, is covered by the conjunctiva (bulbar part)
  • Blood supply: poor (from episcleral vessels)

B. Cornea (Anterior 1/6)

  • Transparent, avascular, highly innervated structure
  • Refractive power: +43 diopters (most powerful refractive surface of the eye)
  • Horizontal diameter: ~11.7 mm; vertical diameter: ~10.6 mm
  • Radius of curvature: ~7.8 mm anteriorly
Five layers of cornea (from anterior to posterior):
LayerKey Features
1. EpitheliumStratified squamous non-keratinized, 5-6 cell layers; regenerates from limbal stem cells
2. Bowman's layerAcellular condensation of anterior stroma; does NOT regenerate if damaged
3. StromaThickest layer (90% of corneal thickness); regular collagen lamellae (orthogonal arrangement = transparency)
4. Descemet's membraneBasement membrane of endothelium; thickens with age; regenerates
5. EndotheliumSingle layer of hexagonal cells; maintains corneal dehydration (deturgescence); does NOT regenerate in adults
Corneoscleral junction = Limbus: Contains Schlemm's canal and trabecular meshwork (aqueous drainage).

2. Uveal Coat (Middle / Vascular Coat)

Also called the uvea or uveal tract. It consists of three parts:

A. Iris (Anteriormost)

  • Colored, opaque diaphragm with central aperture = pupil
  • Two muscles:
    • Sphincter pupillae - circular fibers, constricts pupil (miosis) - parasympathetic (CN III)
    • Dilator pupillae - radial fibers, dilates pupil (mydriasis) - sympathetic (superior cervical ganglion)
  • Two layers of epithelium on posterior surface (both pigmented)
  • Blood supply from major arterial circle of iris (MACI) formed by long posterior ciliary arteries (LPCAs)

B. Ciliary Body (Middle)

  • Triangular in cross-section, located between iris and choroid
  • Two parts:
    • Pars plana (flat part, posterior) - 3.5-4 mm wide; surgical access site (pars plana vitrectomy)
    • Pars plicata (corrugated part, anterior) - bears ~70 ciliary processes
  • Functions:
    • Aqueous humour production by ciliary processes (via active secretion and ultrafiltration)
    • Accommodation via ciliary muscle (Helmholtz theory): circular/longitudinal smooth muscle fibers
  • Ciliary zonules (suspensory ligaments of lens) attach from ciliary body to lens equator
  • Blood supply: anterior ciliary arteries + LPCAs

C. Choroid (Posterior 2/3)

  • Highly vascular, brown/black pigmented layer between sclera and retina
  • Extends from ora serrata anteriorly to optic nerve posteriorly
  • Layers (outside to inside):
    1. Suprachoroid (potential space)
    2. Large vessel layer (Haller's layer)
    3. Medium vessel layer (Sattler's layer)
    4. Choriocapillaris - fenestrated capillaries nourishing outer retina
    5. Bruch's membrane - innermost layer (5 sub-layers), separates choroid from RPE
  • Blood supply: short posterior ciliary arteries (SPCAs)
  • Function: Nourishes outer retina (RPE + photoreceptors); acts as a heat sink

3. Nervous Coat (Inner Coat) - Retina

The retina is a thin, transparent neural tissue lining the posterior 2/3 of the globe.

Extent

  • Anteriorly ends at ora serrata
  • Posteriorly: macula lutea is the area of central vision (~5.5 mm temporal to optic disc)
  • Fovea centralis is the central depression of the macula - area of highest visual acuity (only cones, no rods)
  • Foveal avascular zone (FAZ): ~0.5 mm diameter, no vessels
  • Optic disc (blind spot): 1.5 mm diameter, where optic nerve exits; contains no photoreceptors

Ten Layers of Retina (from outside to inside)

LayerContent
1. RPE (Retinal Pigment Epithelium)Single layer of pigmented cells; phagocytoses shed outer segments; forms outer blood-retinal barrier
2. Photoreceptor layerRods (120 million, peripheral, scotopic/dim light) and Cones (6 million, central, photopic/color)
3. External limiting membraneZonula adherens junctions between Müller cells and photoreceptors
4. Outer nuclear layerNuclei of photoreceptors
5. Outer plexiform layerSynapses between photoreceptors and bipolar/horizontal cells
6. Inner nuclear layerNuclei of bipolar, amacrine, Müller, and horizontal cells
7. Inner plexiform layerSynapses between bipolar, amacrine, and ganglion cells
8. Ganglion cell layerNuclei of ganglion cells
9. Nerve fiber layerAxons of ganglion cells (become optic nerve)
10. Internal limiting membraneBasement membrane of Müller cells; inner boundary
Blood supply of retina:
  • Inner retina (layers 1-6 from inside): central retinal artery (branch of ophthalmic artery)
  • Outer retina (rods/cones, RPE): choriocapillaris (via diffusion through Bruch's membrane)
  • Inner blood-retinal barrier: tight junctions of retinal capillary endothelium
  • Outer blood-retinal barrier: tight junctions of RPE cells

4. Contents of the Eyeball

Aqueous Humour

  • Clear, protein-free fluid
  • Produced by ciliary processes (active secretion ~70%, ultrafiltration ~20%, diffusion ~10%)
  • Fills anterior chamber (between cornea and iris) and posterior chamber (between iris, ciliary body, and lens)
  • Drained via trabecular meshwork → Schlemm's canal → episcleral veins (conventional route)
    • Minor route: uveoscleral (through ciliary body)
  • Normal IOP: 10-21 mmHg
  • Obstructed drainage → raised IOP → glaucoma

Lens

  • Transparent, biconvex, avascular, acellular (no nerves or blood vessels)
  • Refractive power: +18 diopters (at rest); increases with accommodation
  • Parts: anterior capsule > epithelium > cortex > nucleus > posterior capsule
  • Held by zonular fibers (zonules of Zinn) attached to ciliary body
  • Accommodation: ciliary muscle contracts → zonules relax → lens becomes more convex → increased power (near vision)
  • Equatorial lens cells proliferate throughout life → lens grows and becomes less flexible → presbyopia

Vitreous Humour

  • Transparent gel, 99% water + collagen fibrils + hyaluronic acid
  • Fills the vitreous chamber (posterior cavity) = 4/5 of globe volume (~4 mL)
  • Maintains globe shape; supports retina; allows light transmission
  • Attachments: vitreous base (ora serrata), around optic disc, at macula, around retinal vessels
  • Cloquet's canal: remnant of hyaloid artery running through vitreous

5. Chambers of the Eye

ChamberLocationContents
Anterior chamberBetween cornea and irisAqueous humour
Posterior chamberBetween iris, zonule, and lensAqueous humour
Vitreous chamberBetween lens and retinaVitreous humour

6. Accessory Structures

Eyelids

  • Protect the eye; distribute tear film via blinking
  • Layers (outer to inner): Skin → Subcutaneous tissue (no fat) → Orbicularis oculi muscle → Orbital septum → Tarsal plate → Palpebral conjunctiva
  • Tarsal plates: dense fibrous tissue containing Meibomian glands (sebaceous glands, ~25 in upper, ~20 in lower lid)
  • Meibomian glands secrete lipid layer of tear film
  • Glands of Zeis: sebaceous glands of eyelashes
  • Glands of Moll: modified sweat glands

Conjunctiva

  • Thin mucous membrane covering anterior sclera (bulbar conjunctiva) and inner eyelids (palpebral conjunctiva)
  • Goblet cells secrete mucin (innermost layer of tear film)
  • Rich in lymphoid tissue (CALT - conjunctiva-associated lymphoid tissue)

Lacrimal Apparatus

  • Lacrimal gland (superolateral orbit) → secretes aqueous layer of tears
  • Tears flow across cornea and drain via:
    • PunctaCanaliculi (vertical 2 mm then horizontal 8 mm) → common canaliculus → Lacrimal sacNasolacrimal duct → inferior meatus of nose
    • Valve of Rosenmüller (prevents reflux into canaliculi)
    • Valve of Hasner (at nasolacrimal duct opening)
  • Tear film has 3 layers:
    1. Lipid (outer) - from Meibomian glands
    2. Aqueous (middle) - from lacrimal gland
    3. Mucin (inner) - from goblet cells

7. Extraocular Muscles

MusclePrimary ActionNerve Supply
Medial rectusAdductionCN III (oculomotor)
Lateral rectusAbductionCN VI (abducens)
Superior rectusElevation, intorsion, adductionCN III
Inferior rectusDepression, extorsion, adductionCN III
Superior obliqueIntorsion, depression, abductionCN IV (trochlear)
Inferior obliqueExtorsion, elevation, abductionCN III
Mnemonic for nerve supply: LR6SO4, rest by CN3
  • All muscles arise from the annulus of Zinn (common tendinous ring at orbital apex) EXCEPT inferior oblique (from anteromedial orbital floor)
  • All muscles insert into sclera anterior to equator
  • Fick's axes: X (horizontal), Y (sagittal/anteroposterior), Z (vertical) - axes of rotation

8. Blood Supply of the Eye

StructureArtery
Retina (inner)Central retinal artery
ChoroidShort posterior ciliary arteries
Iris, ciliary bodyLong posterior + anterior ciliary arteries
Optic nerve headShort posterior ciliary arteries + circle of Zinn-Haller
Extraocular musclesAnterior ciliary arteries (from muscular branches of ophthalmic artery)
All are branches of the ophthalmic artery (first branch of internal carotid artery).

9. Nerve Supply of the Eye

StructureNerve
Corneal sensationNasociliary branch of V1 (long ciliary nerves)
Pupil constrictionParasympathetic from EW nucleus via CN III → ciliary ganglion → short ciliary nerves
Pupil dilatationSympathetic from superior cervical ganglion → long ciliary nerves
Retina → optic nerveCN II (optic nerve, actually a CNS tract)
AccommodationParasympathetic (CN III → ciliary ganglion → short ciliary nerves → ciliary muscle)

This covers the complete anatomy of the eye as taught in Khurrana's Comprehensive Ophthalmology - the three tunics (fibrous, uveal, retinal), the transparent media, the accessory structures, blood supply, and nerve supply. - Kanski's Clinical Ophthalmology, 10e; Ganong's Review of Medical Physiology, 26e
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