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Give me a proper notes of drugs for respiratory disorder

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These notes cover 14 drug categories for respiratory disorders, compiled from Katzung's Basic & Clinical Pharmacology (16th Ed) and Goodman & Gilman's. Here's a quick overview of what's included:
  1. β₂ Agonists — SABAs (albuterol, terbutaline) and LABAs (salmeterol, formoterol, vilanterol) with mechanisms, routes, toxicities
  2. Inhaled Corticosteroids — All agents (fluticasone, budesonide, ciclesonide, etc.), local vs systemic toxicities, clinical use
  3. Systemic Corticosteroids — Prednisone and methylprednisolone doses for acute severe asthma
  4. Antimuscarinics — SAMAs (ipratropium) and LAMAs (tiotropium, umeclidinium, aclidinium, glycopyrronium); key role in COPD
  5. Methylxanthines — Theophylline/aminophylline with narrow therapeutic index and drug interactions
  6. Leukotriene Inhibitors — Zileuton (5-LOX inhibitor) and LTRAs (montelukast, zafirlukast) including black box warning
  7. Mast Cell Stabilizers — Cromolyn (prophylaxis only, not for acute)
  8. Biologics — Omalizumab, mepolizumab, dupilumab, tezepelumab and selection by biomarker
  9. PDE-4 Inhibitors — Roflumilast for severe COPD
  10. Antitussives — Codeine, dextromethorphan, benzonatate
  11. Mucolytics/Expectorants — Acetylcysteine, guaifenesin, ambroxol, dornase alfa
  12. Antihistamines — 1st vs 2nd generation, role in allergic rhinitis
  13. Pulmonary Hypertension drugs — Sildenafil, bosentan, epoprostenol, riociguat
  14. CFTR Modulators — Trikafta (elexacaftor/tezacaftor/ivacaftor) for cystic fibrosis
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