You are answering a USMLE-style medical question. Question: A 55-year-old woman presents with severe pruritus and fatigue. She denies any similar symptoms in the past. No significant past medical history. Upon physical examination, scleral icterus is present, and significant hepatosplenomegaly is noted. Mild peripheral edema is also present. Laboratory findings are significant for elevated serum levels of bilirubin, aminotransferases, alkaline phosphatase (ALP), γ-glutamyl transpeptidase (GGTP), immunoglobulins, as well as cholesterol (especially HDL fraction). Antiviral antibodies are not present. The erythrocyte sedimentation rate is also elevated. Anti-mitochondrial antibodies are found. A liver biopsy is performed, and the histopathologic examination shows bile duct injury, cholestasis, and granuloma formation. Which of the following is the most likely diagnosis in this patient? Options: A) Primary biliary cirrhosis B) Hemolytic anemia C) Hepatitis A D) Gilbert syndrome Reply with ONLY the letter of the correct answer (A, B, C, or D). No explanation.