National immunization schedule with dose route

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Now let me search the library and web simultaneously for the national immunization schedule.

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Searching the Web

India national immunization schedule 2025 dose route site age

Now let me read the Park's textbook section on National Immunization Schedule and extract the IMA PDF for complete details.

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Reading Web Page

https://ima-india.org/ima/pdfdata/Immunization_Schedule_CHAR…

Now let me also read the Park's NIS table block for the UIP schedule with full route/site details.

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I now have comprehensive data from Park's textbook, IMA recommendations, and the NIS (UIP). Let me compile the full, well-structured answer.

National Immunization Schedule - India

There are two parallel schedules used in India:

National Immunization Schedule (NIS) / Universal Immunization Programme (UIP) - Government of India, free at all public health centres
IAP (Indian Academy of Pediatrics) / IMA Schedule - Recommended comprehensive schedule (includes additional vaccines)

Part A: UIP / National Immunization Schedule (Government of India)

Beneficiary	Age	Vaccine	Dose	Route	Site
Infants	At Birth	BCG	0.1 mL (neonates: 0.05 mL)	Intradermal (ID)	Left upper arm
		bOPV-0 (zero dose)	2 drops	Oral	Mouth
		Hepatitis B (birth dose)	0.5 mL	IM	Left anterolateral thigh
	6 Weeks	bOPV-1	2 drops	Oral	Mouth
		Pentavalent-1 (DPT+HepB+Hib)	0.5 mL	IM	Anterolateral thigh
		fIPV-1 (fractional IPV)	0.1 mL	Intradermal (ID)	Right anterolateral thigh
		RVV-1 (Rotavirus)	5 drops	Oral	Mouth
		PCV-1	0.5 mL	IM	Anterolateral thigh
	10 Weeks	bOPV-2	2 drops	Oral	Mouth
		Pentavalent-2	0.5 mL	IM	Anterolateral thigh
		RVV-2	5 drops	Oral	Mouth
	14 Weeks	bOPV-3	2 drops	Oral	Mouth
		Pentavalent-3	0.5 mL	IM	Anterolateral thigh
		fIPV-2	0.1 mL	ID	Right anterolateral thigh
		RVV-3	5 drops	Oral	Mouth
		PCV-2	0.5 mL	IM	Anterolateral thigh
	9-11 Months	MR-1 (Measles-Rubella)	0.5 mL	SC	Right upper arm
		JE-1 (Japanese Encephalitis)	0.5 mL	SC	Right upper arm
		PCV Booster	0.5 mL	IM	Anterolateral thigh
		fIPV-3	0.1 mL	ID	Right anterolateral thigh
		Vitamin A (1st dose)	1 lakh IU (1 mL)	Oral	Mouth
Children	16-23 Months	MR-2	0.5 mL	SC	Right upper arm
		JE-2	0.5 mL	SC	Right upper arm
		DPT Booster-1	0.5 mL	IM	Anterolateral thigh
		bOPV Booster	2 drops	Oral	Mouth
		Vitamin A (2nd-9th dose, every 6 months up to 5 yrs)	2 lakh IU (1 mL)	Oral	Mouth
	5-6 Years	DPT Booster-2	0.5 mL	IM	Upper arm
	10 Years	Td	0.5 mL	IM	Upper arm
	16 Years	Td	0.5 mL	IM	Upper arm
Pregnant Women	At registration / 1st ANC	Td-1	0.5 mL	IM	Upper arm
	4 weeks after Td-1	Td-2	0.5 mL	IM	Upper arm
	(If previously vaccinated within 3 yrs)	Td Booster	0.5 mL	IM	Upper arm

Key notes:

Pentavalent = DPT + Hepatitis B + Hib (5-in-1 vaccine)

fIPV = fractional dose Inactivated Polio Vaccine (1/5th of full dose) given intradermally

JE vaccine is part of NIS in endemic states (UP, Bihar, West Bengal, Assam, Karnataka, etc.)

Td replaced TT in India's NIS

Part B: IAP / IMA Comprehensive Schedule (0-18 Years)

Age	Vaccine	Dose	Route	Site	Remarks
Birth	BCG	0.05 mL	ID	Left upper arm	Within 24-72 h
	OPV-0	2 drops	Oral	-	Before hospital discharge
	Hep B-0	0.5 mL	IM	Left thigh	Mandatory before discharge
6 Weeks	DTwP/DTaP-1	0.5 mL	IM	Anterolateral thigh	Use combination vaccines
	Hib-1	0.5 mL	IM	Anterolateral thigh
	IPV-1	0.5 mL	IM	Anterolateral thigh
	Hep B-1	0.5 mL	IM	Anterolateral thigh
	PCV10/13-1	0.5 mL	IM	Anterolateral thigh
	Rota-1	0.5-2 mL	Oral	Squirt toward buccal mucosa	Do not give after 16 weeks
10 Weeks	DTwP/DTaP-2	0.5 mL	IM	Anterolateral thigh
	Hib-2	0.5 mL	IM	Anterolateral thigh
	IPV-2	0.5 mL	IM	Anterolateral thigh
	Hep B-2	0.5 mL	IM	Anterolateral thigh
	PCV10/13-2	0.5 mL	IM	Anterolateral thigh
	Rota-2	0.5-2 mL	Oral	Buccal mucosa	2 doses for RV1
14 Weeks	DTwP/DTaP-3	0.5 mL	IM	Anterolateral thigh
	Hib-3	0.5 mL	IM	Anterolateral thigh
	IPV-3	0.5 mL	IM	Anterolateral thigh
	Hep B-3	0.5 mL	IM	Anterolateral thigh
	PCV10/13-3	0.5 mL	IM	Anterolateral thigh
	Rota-3	0.5-2 mL	Oral	Buccal mucosa	RV5/RV116E (3 doses)
6 Months	Hep B	0.5 mL	IM	-	If following 0, 1, 6 month schedule
	OPV-1	2 drops	Oral	-
	IIV-1 (Influenza)	0.25 mL	IM	-	High-risk groups
7 Months	IIV-2 (Influenza)	0.25 mL	IM	-	2nd dose if first given at 6 months
9 Months	OPV-2	2 drops	Oral	-
	MMR-1 / MR	0.5 mL	SC	Right upper arm	After 270 completed days
	Meningococcal-1	0.5 mL	IM	-	High-risk groups
10 Months	Typhoid Conjugate (TCV)-1	0.5 mL	IM	-	≥1 month gap after MMR
12 Months	Hepatitis A-1 (killed or live)	0.5 mL	IM (killed) or SC (live)	-	Single dose if live vaccine
	JE-1	0.25 mL	IM	-	Endemic areas, <3 years
	Cholera	-	Oral	-	Hyperendemic/outbreak areas
13 Months	JE-2	0.25 mL	IM	-	Endemic areas
15 Months	MMR-2	0.5 mL	SC	-
	Varicella-1	0.5 mL	SC	-
15-18 Months	PCV Booster	0.5 mL	IM	-
16-18 Months	DTwP/DTaP Booster-1	0.5 mL	IM	-	Combination vaccines preferred
	IPV Booster	0.5 mL	IM	-
	Hib Booster	0.5 mL	IM	-
18 Months	Hepatitis A-2 (killed)	0.5 mL	IM	-	2nd dose only for killed vaccine
2 Years	TCV-2 or Typhoid polysaccharide	0.5 mL	IM	Upper arm
	Meningococcal-2	0.5 mL	IM	-	Single dose if first dose at/after 2 yrs
4-6 Years	DTwP/DTaP/Tdap (Booster-2)	0.5 mL	IM	Upper arm
	OPV-3 (up to 5 years)	2 drops	Oral	-
	MMR-3	0.5 mL	SC	-
	Varicella-2	0.5 mL	SC	-	Min 3 months after first dose
9 Years+ (girls)	HPV	0.5 mL	IM	Upper arm	2 doses (6 months apart) if started before 15th birthday; 3 doses if started at/after 15 yrs
10 Years	Td / Tdap	0.5 mL	IM	Upper arm
16 Years	Td	0.5 mL	IM	Upper arm

Route Summary (Quick Reference)

Route	Vaccines
Intradermal (ID)	BCG (0.05-0.1 mL), fIPV (0.1 mL)
Oral	OPV, Rotavirus, Cholera, Vitamin A
Subcutaneous (SC)	MMR, Varicella, Hepatitis A (live), JE (some formulations)
Intramuscular (IM)	Hep B, DPT/DTwP/DTaP, Pentavalent, IPV (full dose), Hib, PCV, TCV, Typhoid, Meningococcal, HPV, Td, IIV (influenza)

Special Notes

Pentavalent replaces separate DPT + Hep B + Hib in the government UIP - do not give all three separately if pentavalent is used
fIPV (fractional IPV): Given ID in the anterolateral thigh at 6 and 14 weeks + 9 months under UIP as an effective dose-sparing strategy
BCG dose: 0.05 mL in neonates, 0.1 mL in children >1 month
Rotavirus: First dose must not be given after 16 weeks; last dose not after 8 months (varies by brand)
JE vaccine: Included in UIP only in endemic states
HPV: Included in NIS for girls 9-14 years in India (government program expanding state by state)

Sources: NIS - Government of India UIP; IAP/IMA Immunization Schedule Chart; Park's Textbook of Preventive and Social Medicine, 26th ed.

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