FESS: Anaesthesia Implications for MD Anaesthesia Viva
FESS = functional endoscopic sinus surgery, commonly performed for chronic rhinosinusitis with/without polyposis, recurrent sinusitis, fungal disease, mucoceles, epistaxis, selected tumors, and orbital decompression.
Anaesthetic goals
- Dry, bloodless operative field
- Immobility
- Stable haemodynamics and ventilation
- Protection from aspiration of blood
- Smooth, non-coughing emergence
- Early detection and management of rare but catastrophic orbital, vascular, and intracranial complications.
Miller emphasizes these four central goals: a blood-free field, immobility, stable cardiorespiratory conditions, and gentle emergence.
Miller's Anesthesia, 10e, p. 9812
1. Preoperative assessment
History
- Indication and extent of surgery: routine FESS versus tumor, skull-base, orbital, revision, or extensive polyposis surgery.
- Severity of nasal obstruction, mouth breathing, snoring and obstructive sleep apnea.
- Asthma, aspirin-exacerbated respiratory disease, allergic fungal sinusitis.
- Previous surgery, radiation, trauma, difficult airway, prior major epistaxis.
- Drugs:
- Anticoagulants, antiplatelets, NSAIDs, herbal drugs.
- Antihypertensives and beta-blockers.
- Steroids: assess need for perioperative supplementation if prolonged systemic use.
- Comorbidities relevant to controlled hypotension: coronary artery disease, cerebrovascular disease, chronic hypertension, arrhythmias, severe valvular disease, renal impairment, anemia.
Examination and investigations
- Standard airway examination. Nasal route is unavailable, but facial anatomy, mouth opening and OSA are relevant.
- Baseline BP, Hb, coagulation testing where indicated, ECG in appropriate patients.
- Review CT sinuses to understand proximity to orbit, skull base and carotid canal in high-risk surgery.
Important viva point
Avoid aggressive deliberate hypotension in patients with impaired cerebral, coronary, renal, or uteroplacental perfusion reserve. In chronic hypertension, cerebral autoregulation may be shifted rightward.
2. Choice of anaesthetic technique
General anaesthesia
Usually preferred because it provides:
- Complete immobility
- Secure control of ventilation
- Better tolerance of the procedure
- Ability to manage significant bleeding or complications rapidly
TIVA versus volatile anaesthesia
Propofol-based TIVA, usually with a short-acting opioid such as remifentanil, is often favored for better surgical visibility. A 2025 systematic review of 26 RCTs involving 1,472 patients found lower blood loss and shorter operating time with intravenous compared with inhalational anaesthesia, although PONV outcomes varied.
2025 meta-analysis
Mechanisms include lower heart rate and cardiac output. Miller notes propofol-remifentanil can provide better surgical conditions than a traditional balanced volatile-opioid technique.
Miller's Anesthesia, 10e, p. 9812
Airway: ETT or supraglottic airway?
Cuffed oral ETT
- Preferred for prolonged, extensive, revision, skull-base, high-bleeding-risk surgery, reflux/aspiration risk, obesity/OSA, or when controlled ventilation is required.
- Secure the tube well, typically taped to the lower lip/chin and away from the surgical field.
- Use a reinforced tube if tube kinking or surgical interference is anticipated.
Supraglottic airway
- May allow smoother emergence and less coughing.
- May offer improved field conditions in selected low-risk ambulatory cases.
- Disadvantages: less protection against blood and regurgitation, malposition or leakage.
- Miller describes smoother emergence with an SGA but less protection from regurgitation compared with ETT. Miller's Anesthesia, 10e, p. 9812
Exam answer: For major FESS, bleeding risk, skull-base work, or uncertain duration, I would use a cuffed oral ETT.
3. Intraoperative management
Position
- Supine, head elevated 10 to 30 degrees.
- Reverse Trendelenburg/head-up position promotes venous drainage and reduces bleeding.
- Head in neutral position, eyes accessible if possible.
- Protect pressure points.
Monitoring
- Standard ASA monitoring for routine cases.
- Consider arterial line when:
- Deliberate hypotension is planned in a high-risk patient
- Major/revision/skull-base/tumor surgery
- Significant cardiovascular disease
- Anticipated major blood loss
Measures to optimize the surgical field
Non-pharmacological
- Head-up position.
- Normothermia.
- Avoid hypercapnia, coughing, bucking, hypertension, and tachycardia.
- Avoid excessive PEEP if it worsens venous congestion.
- Ensure adequate depth during stimulation.
- Surgeon-administered topical vasoconstrictors and local infiltration.
Topical vasoconstrictors
Commonly used:
- Adrenaline/epinephrine infiltration, often lidocaine 1% with epinephrine 1:100,000.
- Oxymetazoline or xylometazoline pledgets.
- Cocaine-soaked pledgets in some institutions.
Anaesthetic implications
- Communicate clearly before topical/infiltration doses.
- Watch for hypertension, tachyarrhythmia, myocardial ischemia, ventricular arrhythmias, pulmonary edema, and seizures with systemic toxicity.
- Avoid intravascular injection: aspiration, incremental injection, dose accounting.
- Be particularly cautious in ischemic heart disease, uncontrolled hypertension, hyperthyroidism, and arrhythmia.
Miller notes that nasal decongestion and infiltration with lidocaine-epinephrine are typical, with cocaine pledgets also used in some settings.
Miller's Anesthesia, 10e, p. 9812
4. Controlled hypotension
Why?
Even small volumes of blood can obscure the endoscopic field, increasing risk to the orbit, optic nerve, skull base, carotid/ethmoidal vessels, and brain.
Target
- Individualize the BP target.
- In a healthy normotensive adult, a commonly used target is MAP approximately 60-65 mmHg, provided end-organ perfusion is satisfactory.
- Do not treat a numerical target as more important than patient safety.
Methods
- Adequate depth of anaesthesia and analgesia.
- Propofol-remifentanil TIVA.
- Beta-blockade: esmolol is useful when tachycardia contributes to bleeding.
- Dexmedetomidine can reduce HR and sympathetic responses.
- Vasodilators such as nitroglycerin or sodium nitroprusside may reduce BP, but can cause reflex tachycardia and may be less favorable for the surgical field.
- Magnesium may be an adjunct in selected patients.
High-yield statement: Lowering
heart rate and cardiac output is often more beneficial to the surgical field than isolated arterial vasodilatation. Miller states that beta-adrenergic blockade yields better operating conditions than vasodilator drugs when controlled hypotension is used.
Miller's Anesthesia, 10e, p. 9812
Contraindications or major cautions
- Significant coronary artery disease
- Critical cerebrovascular disease
- Severe anemia/hypovolemia
- Severe aortic stenosis or obstructive cardiomyopathy
- Uncontrolled arrhythmias
- Severe renal dysfunction
- Pregnancy and compromised uteroplacental circulation
- Elderly/frail patients or those with poor autoregulatory reserve
5. Fluid and blood management
- Usually low blood loss, but blood loss can become substantial unexpectedly.
- Obtain IV access appropriate to case complexity.
- Use balanced crystalloid judiciously.
- Avoid fluid overload, which can worsen mucosal edema.
- Crossmatch blood for extensive/revision/tumor/skull-base cases.
- Maintain normothermia and correct coagulopathy if present.
6. Critical surgical complications and anaesthetic response
A. Massive hemorrhage
May arise from sphenopalatine, anterior/posterior ethmoidal, internal maxillary, or rarely carotid injury.
Management
- Inform surgeon and call for help.
- Stop surgery/pack nose.
- 100% oxygen, secure airway, suction continuously.
- Two large-bore IV lines, arterial line, blood products and massive hemorrhage protocol if necessary.
- Correct hypotension, hypocalcemia, acidosis, and coagulopathy.
- Prepare for conversion, interventional radiology, or vascular assistance.
B. Orbital injury or retrobulbar hematoma
Signs: proptosis, tense orbit, chemosis, rapidly swollen eyelids, ophthalmoplegia, loss of pupillary response, rising intraocular pressure.
Action
- Immediate communication with surgeon.
- This is a vision-threatening emergency.
- Urgent orbital decompression/canthotomy-cantholysis may be required.
- Avoid hypotension in this situation and restore adequate perfusion.
C. CSF leak or intracranial entry
- Stop surgical dissection.
- Maintain stable haemodynamics and avoid coughing/straining.
- Facilitate repair; consider neurosurgical involvement.
- Postoperative observation for CSF rhinorrhea, meningitis, pneumocephalus, and neurological signs.
D. Venous air embolism
Rare, but possible in head-up position and venous injury.
- Sudden fall in ETCO₂, hypoxia, hypotension, mill-wheel murmur.
- Stop surgery, flood field, 100% oxygen, support circulation, reduce head elevation if feasible.
E. Aspiration of blood
- Meticulous suctioning.
- Throat pack only if local protocol supports it, with a documented insertion-removal check.
- Suction pharynx thoroughly before emergence.
- Consider awake extubation when bleeding/aspiration risk is significant.
Major FESS complications include orbital hematoma, blindness, CSF leak, carotid or ethmoid artery injury, intracranial entry, severe hemorrhage, and death.
Miller's Anesthesia, 10e, p. 9812
7. Emergence and postoperative care
Emergence
The key objective is to prevent coughing, bucking, hypertension, bleeding, and laryngospasm.
- Ensure full reversal of neuromuscular blockade.
- Thorough oral and pharyngeal suctioning under direct vision where possible.
- Remove throat pack with a documented check.
- Provide analgesia, antiemetic prophylaxis, and adequate oxygenation.
- Consider lidocaine, opioid titration, dexmedetomidine, or remifentanil strategy to blunt emergence responses.
- Extubate fully awake when aspiration risk is present. Deep extubation is only for carefully selected, low-risk patients with a clean airway.
Analgesia
Usually mild to moderate pain:
- Paracetamol
- NSAID/COX-2 inhibitor if surgeon permits and bleeding risk is acceptable
- Small titrated opioid doses
- Local infiltration by surgeon
PONV prophylaxis
FESS patients are at high risk because swallowed blood is emetogenic.
- Use multimodal prophylaxis: dexamethasone plus ondansetron, with further agents according to risk.
- Minimize opioid use.
- TIVA may also be useful in high-PONV-risk patients.
Postoperative observation
Monitor for:
- Epistaxis or concealed swallowed blood
- Airway obstruction/laryngospasm
- Nausea, vomiting and aspiration
- Hypertension causing rebleeding
- Visual symptoms, proptosis, altered consciousness, severe headache, or CSF rhinorrhea
One-minute viva answer
“FESS is an endoscopic ENT procedure in which the principal anaesthetic problem is maintaining a dry surgical field without compromising organ perfusion. I assess for OSA, asthma, aspirin sensitivity, anticoagulants, steroid use, cardiovascular disease, anemia and suitability for controlled hypotension. General anaesthesia is usual. For extensive or high-bleeding-risk cases I use a cuffed oral ETT; an SGA may be suitable for selected minor ambulatory cases but provides less protection from blood aspiration. I use head-up positioning, normocapnia, adequate anaesthetic depth, topical vasoconstrictor vigilance, and often propofol-based TIVA with control of heart rate. Controlled hypotension is individualized, commonly around MAP 60-65 mmHg in healthy patients, but is avoided or used cautiously in coronary or cerebrovascular disease and other low-perfusion states. Emergence must be smooth, with confirmed throat-pack removal, meticulous suctioning, full reversal, PONV prophylaxis, and monitoring for hemorrhage, aspiration, orbital injury and CSF leak.”