python3 -c " import pdfplumber pdf_path = '/home/daytona/workspace/attachments/c…

mkdir -p /home/daytona/workspace/journal-club-cbct && ls /home/daytona/workspace…

~/journal-club-cbct/create_pptx.js

const pptxgen = require("pptxgenjs");

let pres = new pptxgen();
pres.layout = 'LAYOUT_16x9';
pres.author = 'Journal Club';
pres.title = 'CBCT-Guided Biomimetic Management of Internal Inflammatory Resorption';

// Color palette - deep teal/dark blue dental theme
const DARK_BG = "0D2B45";       // dark navy blue – title/section slides
const LIGHT_BG = "F4F7FB";      // near-white – content slides
const ACCENT = "1BADA6";        // teal accent
const ACCENT2 = "E84855";       // coral red for highlights
const TEXT_DARK = "0D2B45";     // navy for body text on light bg
const TEXT_LIGHT = "FFFFFF";    // white text on dark bg
const SUBTEXT = "5A7A94";       // muted blue-gray
const CARD_BG = "FFFFFF";       // white card
const STRIPE = "E0EBF5";        // light blue stripe

// Helper: add a dark background slide header bar
function addSlide(bg) {
  let s = pres.addSlide();
  s.addShape(pres.ShapeType.rect, { x: 0, y: 0, w: 10, h: 5.625, fill: { color: bg || LIGHT_BG }, line: { type: "none" } });
  return s;
}

function addSectionHeader(label) {
  let s = pres.addSlide();
  s.addShape(pres.ShapeType.rect, { x: 0, y: 0, w: 10, h: 5.625, fill: { color: DARK_BG }, line: { type: "none" } });
  s.addShape(pres.ShapeType.rect, { x: 0, y: 2.3, w: 0.18, h: 1.1, fill: { color: ACCENT }, line: { type: "none" } });
  s.addText(label, {
    x: 0.4, y: 2.25, w: 9.2, h: 1.2,
    fontSize: 36, bold: true, color: TEXT_LIGHT, fontFace: "Calibri", valign: "middle"
  });
  return s;
}

function slideTitle(slide, title) {
  // Top accent bar
  slide.addShape(pres.ShapeType.rect, { x: 0, y: 0, w: 10, h: 0.55, fill: { color: DARK_BG }, line: { type: "none" } });
  slide.addShape(pres.ShapeType.rect, { x: 0, y: 0.55, w: 10, h: 0.04, fill: { color: ACCENT }, line: { type: "none" } });
  slide.addText(title, {
    x: 0.35, y: 0, w: 9.3, h: 0.58,
    fontSize: 16, bold: true, color: TEXT_LIGHT, fontFace: "Calibri", valign: "middle", margin: 0
  });
}

function bullets(slide, items, x, y, w, h, opts) {
  let rows = items.map((item, i) => ({
    text: item,
    options: { bullet: { code: "2022" }, color: opts && opts.color ? opts.color : TEXT_DARK, fontSize: opts && opts.fontSize ? opts.fontSize : 14, fontFace: "Calibri", paraSpaceAfter: 6, breakLine: i < items.length - 1 }
  }));
  slide.addText(rows, { x, y, w, h, valign: "top" });
}

// ─── SLIDE 1: TITLE ─────────────────────────────────────────────────────────
{
  let s = pres.addSlide();
  // Full dark background
  s.addShape(pres.ShapeType.rect, { x: 0, y: 0, w: 10, h: 5.625, fill: { color: DARK_BG }, line: { type: "none" } });
  // Teal bottom stripe
  s.addShape(pres.ShapeType.rect, { x: 0, y: 4.8, w: 10, h: 0.825, fill: { color: ACCENT }, line: { type: "none" } });
  // Decorative left bar
  s.addShape(pres.ShapeType.rect, { x: 0.4, y: 0.5, w: 0.12, h: 3.5, fill: { color: ACCENT }, line: { type: "none" } });
  // Journal club label
  s.addText("JOURNAL CLUB PRESENTATION", {
    x: 0.65, y: 0.55, w: 9, h: 0.45,
    fontSize: 11, color: ACCENT, bold: true, fontFace: "Calibri", charSpacing: 3
  });
  // Main title
  s.addText("CBCT-Guided Biomimetic Management of Extensive Internal Inflammatory Resorption", {
    x: 0.65, y: 1.15, w: 8.8, h: 2.1,
    fontSize: 26, bold: true, color: TEXT_LIGHT, fontFace: "Calibri"
  });
  // Subtitle: with histopathologic correlation
  s.addText("with Histopathologic Correlation", {
    x: 0.65, y: 3.05, w: 8.8, h: 0.55,
    fontSize: 18, color: ACCENT, italic: true, fontFace: "Calibri"
  });
  // Horizontal rule
  s.addShape(pres.ShapeType.rect, { x: 0.65, y: 3.65, w: 4, h: 0.03, fill: { color: STRIPE }, line: { type: "none" } });
  // Authors
  s.addText("Z. K. Sincy, Shiji Dinakaran, Keerthana Surendran, C. Leela Krishnan", {
    x: 0.65, y: 3.75, w: 8.8, h: 0.45,
    fontSize: 12, color: TEXT_LIGHT, fontFace: "Calibri"
  });
  // Institution
  s.addText("Dept. of Conservative Dentistry & Endodontics | Govt. Dental College, Thiruvananthapuram, Kerala, India", {
    x: 0.65, y: 4.2, w: 8.8, h: 0.4,
    fontSize: 10, color: SUBTEXT, fontFace: "Calibri"
  });
  // Journal label
  s.addText("Case Report  |  Conservative Dentistry & Endodontics", {
    x: 0.3, y: 4.87, w: 9.4, h: 0.45,
    fontSize: 11, bold: true, color: TEXT_LIGHT, fontFace: "Calibri", align: "center"
  });
}

// ─── SLIDE 2: AGENDA ────────────────────────────────────────────────────────
{
  let s = addSlide(LIGHT_BG);
  slideTitle(s, "Presentation Outline");

  const items = [
    ["Background & Rationale", "What is internal inflammatory resorption? Why is it clinically significant?"],
    ["Case Presentation", "Patient history, clinical examination, radiographic findings"],
    ["CBCT Findings", "3D assessment, lesion extent, perforation status"],
    ["Treatment Protocol", "Nonsurgical RCT, obturation, biomimetic reinforcement"],
    ["Histopathologic Correlation", "Tissue findings confirming the diagnosis"],
    ["Outcomes & Follow-Up", "6-month radiographic and clinical results"],
    ["Discussion & Key Takeaways", "Biomimetic concepts, limitations, future directions"],
  ];

  let yStart = 0.75;
  let rowH = 0.6;

  items.forEach((item, i) => {
    let bg = i % 2 === 0 ? STRIPE : CARD_BG;
    s.addShape(pres.ShapeType.rect, { x: 0.3, y: yStart + i * rowH, w: 9.4, h: rowH - 0.04, fill: { color: bg }, line: { type: "none" }, rounding: 0.06 });
    // Number badge
    s.addShape(pres.ShapeType.ellipse, { x: 0.38, y: yStart + i * rowH + 0.09, w: 0.38, h: 0.38, fill: { color: ACCENT }, line: { type: "none" } });
    s.addText(`${i + 1}`, { x: 0.38, y: yStart + i * rowH + 0.09, w: 0.38, h: 0.38, fontSize: 11, bold: true, color: TEXT_LIGHT, fontFace: "Calibri", align: "center", valign: "middle" });
    s.addText(item[0], { x: 0.88, y: yStart + i * rowH + 0.05, w: 3.5, h: 0.28, fontSize: 12, bold: true, color: TEXT_DARK, fontFace: "Calibri", valign: "top" });
    s.addText(item[1], { x: 0.88, y: yStart + i * rowH + 0.28, w: 8.5, h: 0.28, fontSize: 9, color: SUBTEXT, fontFace: "Calibri", valign: "top" });
  });
}

// ─── SLIDE 3: SECTION – BACKGROUND ──────────────────────────────────────────
addSectionHeader("Background & Rationale");

// ─── SLIDE 4: WHAT IS INTERNAL INFLAMMATORY RESORPTION ───────────────────────
{
  let s = addSlide(LIGHT_BG);
  slideTitle(s, "What is Internal Inflammatory Resorption (IIR)?");

  // Definition box
  s.addShape(pres.ShapeType.rect, { x: 0.3, y: 0.72, w: 9.4, h: 1.0, fill: { color: DARK_BG }, line: { type: "none" }, rounding: 0.1 });
  s.addText("Progressive destruction of intraradicular dentin caused by clastic activity within chronically inflamed vital pulp tissue, resulting in balloon-like widening of the canal space.", {
    x: 0.5, y: 0.72, w: 9.0, h: 1.0, fontSize: 13, color: TEXT_LIGHT, fontFace: "Calibri", italic: true, valign: "middle"
  });

  // Three columns: Etiology / Prevalence / Clinical features
  const cols = [
    { title: "Etiology", items: ["Pulpal trauma (most common)", "Caries, deep restorations", "Orthodontic forces", "Chronic pulpitis"], icon: "⚡" },
    { title: "Characteristics", items: ["Uncommon, often asymptomatic", "Pink/gray discoloration", "Balloon-like radiolucency on X-ray", "Cervical region most vulnerable"], icon: "🔍" },
    { title: "Challenge", items: ["Silent until significant damage", "2D X-ray underestimates extent", "Differentiation from external resorption difficult", "Risk of perforation"], icon: "⚠️" },
  ];

  cols.forEach((col, i) => {
    let x = 0.3 + i * 3.2;
    s.addShape(pres.ShapeType.rect, { x, y: 1.85, w: 3.0, h: 3.4, fill: { color: i === 2 ? "FFF0F1" : STRIPE }, line: { color: i === 2 ? ACCENT2 : ACCENT, pt: 1.5 }, rounding: 0.1 });
    s.addText(col.icon + "  " + col.title, { x: x + 0.1, y: 1.92, w: 2.8, h: 0.4, fontSize: 13, bold: true, color: i === 2 ? ACCENT2 : ACCENT, fontFace: "Calibri" });
    s.addShape(pres.ShapeType.rect, { x: x + 0.1, y: 2.32, w: 2.8, h: 0.03, fill: { color: i === 2 ? ACCENT2 : ACCENT }, line: { type: "none" } });
    let bRows = col.items.map((item, j) => ({
      text: item,
      options: { bullet: { code: "25CF" }, color: TEXT_DARK, fontSize: 11, fontFace: "Calibri", paraSpaceAfter: 5, breakLine: j < col.items.length - 1 }
    }));
    s.addText(bRows, { x: x + 0.12, y: 2.4, w: 2.8, h: 2.75, valign: "top" });
  });
}

// ─── SLIDE 5: WHY CBCT? ─────────────────────────────────────────────────────
{
  let s = addSlide(LIGHT_BG);
  slideTitle(s, "Why CBCT? — Diagnostic Superiority");

  // Two-column layout: 2D vs CBCT
  // Left column – Conventional 2D
  s.addShape(pres.ShapeType.rect, { x: 0.3, y: 0.72, w: 4.4, h: 4.6, fill: { color: "FFF0F1" }, line: { color: ACCENT2, pt: 1.5 }, rounding: 0.1 });
  s.addShape(pres.ShapeType.rect, { x: 0.3, y: 0.72, w: 4.4, h: 0.55, fill: { color: ACCENT2 }, line: { type: "none" }, rounding: 0.1 });
  s.addText("Conventional 2D Radiography", { x: 0.4, y: 0.72, w: 4.2, h: 0.55, fontSize: 13, bold: true, color: TEXT_LIGHT, fontFace: "Calibri", valign: "middle" });
  let left = ["Only two-dimensional image", "Superimposition of structures", "Cannot determine true lesion extent", "Difficult to distinguish internal from external resorption", "Underestimates remaining dentin thickness", "Perforation status uncertain"];
  let leftRows = left.map((t, i) => ({ text: t, options: { bullet: { code: "2716" }, color: ACCENT2, fontSize: 12, fontFace: "Calibri", paraSpaceAfter: 7, breakLine: i < left.length - 1 } }));
  s.addText(leftRows, { x: 0.48, y: 1.38, w: 4.05, h: 3.8, valign: "top" });

  // Right column – CBCT
  s.addShape(pres.ShapeType.rect, { x: 5.0, y: 0.72, w: 4.7, h: 4.6, fill: { color: "EBF7F6" }, line: { color: ACCENT, pt: 1.5 }, rounding: 0.1 });
  s.addShape(pres.ShapeType.rect, { x: 5.0, y: 0.72, w: 4.7, h: 0.55, fill: { color: ACCENT }, line: { type: "none" }, rounding: 0.1 });
  s.addText("CBCT — 3D Assessment", { x: 5.1, y: 0.72, w: 4.5, h: 0.55, fontSize: 13, bold: true, color: TEXT_LIGHT, fontFace: "Calibri", valign: "middle" });
  let right = ["True 3D morphology of lesion", "Accurate measurement of lesion extent", "Identifies remaining dentin thickness", "Differentiates internal from external resorption", "Detects root perforations", "Guides conservative treatment planning (ESE position statement)"];
  let rightRows = right.map((t, i) => ({ text: t, options: { bullet: { code: "2714" }, color: ACCENT, fontSize: 12, fontFace: "Calibri", paraSpaceAfter: 7, breakLine: i < right.length - 1 } }));
  s.addText(rightRows, { x: 5.12, y: 1.38, w: 4.4, h: 3.8, valign: "top" });
}

// ─── SLIDE 6: SECTION – CASE PRESENTATION ───────────────────────────────────
addSectionHeader("Case Presentation");

// ─── SLIDE 7: PATIENT PROFILE ────────────────────────────────────────────────
{
  let s = addSlide(LIGHT_BG);
  slideTitle(s, "Patient Profile & Chief Complaint");

  // Patient card
  s.addShape(pres.ShapeType.rect, { x: 0.3, y: 0.72, w: 3.8, h: 4.6, fill: { color: DARK_BG }, line: { type: "none" }, rounding: 0.1 });

  s.addText("PATIENT PROFILE", { x: 0.45, y: 0.85, w: 3.5, h: 0.4, fontSize: 10, bold: true, color: ACCENT, fontFace: "Calibri", charSpacing: 2 });
  const profileData = [
    ["Age", "30 years"],
    ["Sex", "Male"],
    ["Tooth", "Maxillary right central incisor (Tooth 11)"],
    ["Chief Complaint", "Progressive discoloration of upper front tooth"],
    ["Duration", "Past few months"],
    ["Pain", "No spontaneous pain"],
    ["Medical Hx", "Non-contributory"],
    ["Past History", "Trauma to anterior teeth ~24 years ago (age 6)"],
  ];
  profileData.forEach(([label, val], i) => {
    s.addText(label + ":", { x: 0.45, y: 1.35 + i * 0.48, w: 1.2, h: 0.42, fontSize: 10, bold: true, color: ACCENT, fontFace: "Calibri" });
    s.addText(val, { x: 1.7, y: 1.35 + i * 0.48, w: 2.2, h: 0.42, fontSize: 10, color: TEXT_LIGHT, fontFace: "Calibri", wrap: true });
  });

  // Right side: clinical findings
  s.addShape(pres.ShapeType.rect, { x: 4.3, y: 0.72, w: 5.4, h: 4.6, fill: { color: STRIPE }, line: { type: "none" }, rounding: 0.1 });
  s.addText("Clinical Examination Findings", { x: 4.5, y: 0.85, w: 5.0, h: 0.4, fontSize: 13, bold: true, color: ACCENT, fontFace: "Calibri" });
  s.addShape(pres.ShapeType.rect, { x: 4.5, y: 1.25, w: 5.0, h: 0.03, fill: { color: ACCENT }, line: { type: "none" } });

  const clinFindings = [
    { label: "Appearance", text: "Discoloration of tooth 11 with cervical thinning; incisal enamel intact" },
    { label: "Percussion/Palpation", text: "Asymptomatic" },
    { label: "Periodontal probing", text: "Within normal limits" },
    { label: "Thermal test", text: "Exaggerated but non-lingering response (Endo-Frost)" },
    { label: "Swelling/sinus tract", text: "Absent" },
    { label: "Mobility", text: "Normal" },
    { label: "Periapical X-ray", text: "Well-defined radiolucent enlargement in coronal/cervical pulp space — balloon-like appearance; intact external root contour; mild widening of apical PDL space" },
  ];
  clinFindings.forEach((f, i) => {
    let yy = 1.38 + i * 0.48;
    s.addText(f.label + ":", { x: 4.5, y: yy, w: 1.8, h: 0.44, fontSize: 10, bold: true, color: TEXT_DARK, fontFace: "Calibri" });
    s.addText(f.text, { x: 6.3, y: yy, w: 3.3, h: 0.44, fontSize: 10, color: TEXT_DARK, fontFace: "Calibri", wrap: true });
  });
}

// ─── SLIDE 8: CBCT FINDINGS ──────────────────────────────────────────────────
{
  let s = addSlide(LIGHT_BG);
  slideTitle(s, "CBCT Findings & Diagnosis");

  // Protocol box
  s.addShape(pres.ShapeType.rect, { x: 0.3, y: 0.72, w: 9.4, h: 0.75, fill: { color: DARK_BG }, line: { type: "none" }, rounding: 0.08 });
  s.addText("CBCT Protocol: Limited FOV (6 cm × 6 cm) to evaluate lesion extent and rule out external cervical resorption", {
    x: 0.5, y: 0.72, w: 9.1, h: 0.75, fontSize: 12, color: TEXT_LIGHT, fontFace: "Calibri", italic: true, valign: "middle"
  });

  // CBCT findings cards
  const findings = [
    { title: "Lesion Location", desc: "Cervical third of tooth 11", color: ACCENT },
    { title: "External Surface", desc: "Intact — no perforation detected", color: "2E8B57" },
    { title: "Lesion Character", desc: "Internal resorption confirmed — balloon-like expansion of pulp space", color: ACCENT },
    { title: "Perforation Status", desc: "Absent — conservative orthograde approach feasible", color: "2E8B57" },
  ];
  findings.forEach((f, i) => {
    let x = 0.3 + (i % 2) * 4.85;
    let y = 1.62 + Math.floor(i / 2) * 1.75;
    s.addShape(pres.ShapeType.rect, { x, y, w: 4.55, h: 1.6, fill: { color: CARD_BG }, line: { color: f.color, pt: 2 }, rounding: 0.1 });
    s.addShape(pres.ShapeType.rect, { x, y, w: 4.55, h: 0.42, fill: { color: f.color }, line: { type: "none" }, rounding: 0.1 });
    s.addText(f.title, { x: x + 0.15, y, w: 4.3, h: 0.42, fontSize: 12, bold: true, color: TEXT_LIGHT, fontFace: "Calibri", valign: "middle" });
    s.addText(f.desc, { x: x + 0.15, y: y + 0.5, w: 4.3, h: 1.0, fontSize: 12, color: TEXT_DARK, fontFace: "Calibri", valign: "top", wrap: true });
  });

  // AAE Diagnosis box
  s.addShape(pres.ShapeType.rect, { x: 0.3, y: 5.05, w: 9.4, h: 0.45, fill: { color: ACCENT }, line: { type: "none" }, rounding: 0.08 });
  s.addText("AAE Diagnosis: Asymptomatic Irreversible Pulpitis with Asymptomatic Apical Periodontitis", {
    x: 0.5, y: 5.05, w: 9.1, h: 0.45, fontSize: 12, bold: true, color: TEXT_LIGHT, fontFace: "Calibri", valign: "middle"
  });
}

// ─── SLIDE 9: SECTION – TREATMENT ───────────────────────────────────────────
addSectionHeader("Treatment Protocol");

// ─── SLIDE 10: TREATMENT STEPS ──────────────────────────────────────────────
{
  let s = addSlide(LIGHT_BG);
  slideTitle(s, "Treatment Protocol — Nonsurgical Root Canal Therapy");

  const steps = [
    { num: "1", title: "Access & Tissue Extirpation", detail: "Rubber dam isolation | Conventional access cavity | Vascular pulp-like tissue extirpated & sent for histopath in 10% neutral buffered formalin" },
    { num: "2", title: "Chemomechanical Preparation", detail: "Working length: Electronic apex locator (Root ZX) + radiographic confirmation | Rotary NiTi system: Orodeka Plex V (25/0.06, crown-down) | Irrigation: 5.25% NaOCl + 17% EDTA (RC Help) + saline" },
    { num: "3", title: "Intracanal Medication", detail: "Calcium hydroxide (RC Cal) placed | Temporary seal — patient reviewed at next appointment, asymptomatic" },
    { num: "4", title: "Obturation", detail: "Single-cone gutta-percha (Dentsply Sirona) + Bioceramic sealer BioRoot RCS (Septodont) | Satisfactory adaptation to irregular canal anatomy confirmed radiographically" },
  ];

  steps.forEach((step, i) => {
    let y = 0.72 + i * 1.2;
    s.addShape(pres.ShapeType.rect, { x: 0.3, y, w: 9.4, h: 1.1, fill: { color: i % 2 === 0 ? STRIPE : CARD_BG }, line: { color: ACCENT, pt: 0.75 }, rounding: 0.08 });
    s.addShape(pres.ShapeType.rect, { x: 0.3, y, w: 0.7, h: 1.1, fill: { color: ACCENT }, line: { type: "none" }, rounding: 0.08 });
    s.addText(step.num, { x: 0.3, y, w: 0.7, h: 1.1, fontSize: 22, bold: true, color: TEXT_LIGHT, fontFace: "Calibri", align: "center", valign: "middle" });
    s.addText(step.title, { x: 1.1, y: y + 0.08, w: 8.4, h: 0.38, fontSize: 13, bold: true, color: ACCENT, fontFace: "Calibri" });
    s.addText(step.detail, { x: 1.1, y: y + 0.45, w: 8.4, h: 0.6, fontSize: 10.5, color: TEXT_DARK, fontFace: "Calibri", wrap: true });
  });
}

// ─── SLIDE 11: BIOMIMETIC REINFORCEMENT ─────────────────────────────────────
{
  let s = addSlide(LIGHT_BG);
  slideTitle(s, "Biomimetic Reinforcement Strategy");

  // Concept explanation at top
  s.addShape(pres.ShapeType.rect, { x: 0.3, y: 0.72, w: 9.4, h: 0.7, fill: { color: DARK_BG }, line: { type: "none" }, rounding: 0.08 });
  s.addText("Biomimetic Concept: Preserve and reinforce compromised tooth structure using fiber-reinforced composite — avoiding aggressive post preparation", {
    x: 0.5, y: 0.72, w: 9.1, h: 0.7, fontSize: 12, color: TEXT_LIGHT, italic: true, fontFace: "Calibri", valign: "middle"
  });

  // Steps in order
  const rSteps = [
    { title: "Gutta-percha Removal", text: "~2 mm of GP removed from canal orifice to create space for reinforcement" },
    { title: "Adhesive System", text: "Clearfil SE Bond (Kuraray) applied + light-cured — self-etch protocol" },
    { title: "Flowable Composite Base", text: "Estelite Flow Quick (Tokuyama) placed at orifice as matrix" },
    { title: "Polyethylene Fiber (Ribbond)", text: "Adapted within composite — acts as stress-distributing scaffold; limits crack propagation; internal splint effect" },
    { title: "Fiber-Reinforced Composite", text: "everX Flow (GC Corp) placed at cervical region — reinforces thinned dentin, improves fracture resistance" },
    { title: "Bulk-Fill Composite", text: "Filtek Bulk Fill (3M ESPE) for remaining coronal restoration — finishing & polishing restores natural contour" },
  ];

  rSteps.forEach((step, i) => {
    let col = i % 2;
    let row = Math.floor(i / 2);
    let x = 0.3 + col * 4.85;
    let y = 1.58 + row * 1.3;
    s.addShape(pres.ShapeType.rect, { x, y, w: 4.55, h: 1.22, fill: { color: STRIPE }, line: { color: ACCENT, pt: 1 }, rounding: 0.08 });
    // Step number
    s.addShape(pres.ShapeType.ellipse, { x: x + 0.1, y: y + 0.12, w: 0.36, h: 0.36, fill: { color: ACCENT }, line: { type: "none" } });
    s.addText(`${i + 1}`, { x: x + 0.1, y: y + 0.12, w: 0.36, h: 0.36, fontSize: 10, bold: true, color: TEXT_LIGHT, fontFace: "Calibri", align: "center", valign: "middle" });
    s.addText(step.title, { x: x + 0.55, y: y + 0.08, w: 3.9, h: 0.38, fontSize: 11, bold: true, color: TEXT_DARK, fontFace: "Calibri" });
    s.addText(step.text, { x: x + 0.12, y: y + 0.48, w: 4.3, h: 0.68, fontSize: 10, color: TEXT_DARK, fontFace: "Calibri", wrap: true });
  });
}

// ─── SLIDE 12: SECTION – HISTOPATH ──────────────────────────────────────────
addSectionHeader("Histopathologic Correlation");

// ─── SLIDE 13: HISTOPATH FINDINGS ───────────────────────────────────────────
{
  let s = addSlide(LIGHT_BG);
  slideTitle(s, "Histopathologic Examination — H&E Staining");

  // Two columns
  // Left: method
  s.addShape(pres.ShapeType.rect, { x: 0.3, y: 0.72, w: 4.0, h: 4.65, fill: { color: DARK_BG }, line: { type: "none" }, rounding: 0.1 });
  s.addText("Specimen", { x: 0.45, y: 0.82, w: 3.6, h: 0.38, fontSize: 11, bold: true, color: ACCENT, fontFace: "Calibri", charSpacing: 2 });
  s.addText("Pulp-like vascular tissue extirpated from resorptive cavity during access", { x: 0.45, y: 1.22, w: 3.6, h: 0.7, fontSize: 11, color: TEXT_LIGHT, fontFace: "Calibri", italic: true });

  s.addText("Preservation", { x: 0.45, y: 2.0, w: 3.6, h: 0.38, fontSize: 11, bold: true, color: ACCENT, fontFace: "Calibri", charSpacing: 2 });
  s.addText("10% neutral buffered formalin", { x: 0.45, y: 2.4, w: 3.6, h: 0.4, fontSize: 11, color: TEXT_LIGHT, fontFace: "Calibri" });

  s.addText("Staining", { x: 0.45, y: 2.9, w: 3.6, h: 0.38, fontSize: 11, bold: true, color: ACCENT, fontFace: "Calibri", charSpacing: 2 });
  s.addText("Haematoxylin & Eosin (H&E)", { x: 0.45, y: 3.3, w: 3.6, h: 0.4, fontSize: 11, color: TEXT_LIGHT, fontFace: "Calibri" });

  s.addText("Significance", { x: 0.45, y: 3.82, w: 3.6, h: 0.38, fontSize: 11, bold: true, color: ACCENT, fontFace: "Calibri", charSpacing: 2 });
  s.addText("Biological confirmation of IIR — rarely documented in clinical case reports", { x: 0.45, y: 4.22, w: 3.6, h: 0.7, fontSize: 11, color: TEXT_LIGHT, fontFace: "Calibri", italic: true });

  // Right: findings
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  s.addText("Histopathologic Findings", { x: 4.65, y: 0.82, w: 4.8, h: 0.4, fontSize: 13, bold: true, color: ACCENT, fontFace: "Calibri" });
  s.addShape(pres.ShapeType.rect, { x: 4.65, y: 1.22, w: 4.8, h: 0.03, fill: { color: ACCENT }, line: { type: "none" } });

  const histoFindings = [
    { icon: "1", text: "Fibrovascular connective tissue" },
    { icon: "2", text: "Chronic inflammatory cell infiltration" },
    { icon: "3", text: "Dilated blood vessels" },
    { icon: "4", text: "Resorptive lacunae adjacent to dentinal fragments (Howship's lacunae)" },
    { icon: "5", text: "Multinucleated giant cells — consistent with odontoclast-like activity" },
    { icon: "✓", text: "All findings consistent with chronic pulpal inflammation and internal inflammatory resorption" },
  ];
  histoFindings.forEach((f, i) => {
    let isLast = i === histoFindings.length - 1;
    let y = 1.35 + i * 0.58;
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    s.addText(f.icon, { x: 4.7, y, w: 0.32, h: 0.32, fontSize: 9, bold: true, color: TEXT_LIGHT, fontFace: "Calibri", align: "center", valign: "middle" });
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  });
}

// ─── SLIDE 14: SECTION – OUTCOMES ───────────────────────────────────────────
addSectionHeader("Outcomes & Follow-Up");

// ─── SLIDE 15: OUTCOMES ──────────────────────────────────────────────────────
{
  let s = addSlide(LIGHT_BG);
  slideTitle(s, "Clinical Outcomes — Follow-Up at 1 Week & 6 Months");

  // Timeline bar
  const timepoints = [
    { label: "Day 0", sub: "Treatment completed", color: ACCENT },
    { label: "1 Week", sub: "First follow-up", color: ACCENT },
    { label: "6 Months", sub: "Review", color: "2E8B57" },
  ];
  timepoints.forEach((tp, i) => {
    let x = 1.0 + i * 3.5;
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      s.addShape(pres.ShapeType.rect, { x: x + 0.55, y: 1.0, w: 3.5 - 0.55, h: 0.08, fill: { color: STRIPE }, line: { type: "none" } });
    }
  });

  // Two outcome cards
  const cards = [
    {
      title: "1-Week Follow-Up",
      items: ["No discomfort reported", "Satisfactory aesthetics", "Good marginal adaptation of restoration"],
      color: ACCENT
    },
    {
      title: "6-Month Follow-Up",
      items: [
        "Tooth asymptomatic and functional",
        "No progression of resorptive defect on radiograph",
        "Reduction in apical PDL space widening",
        "Obturation integrity maintained",
        "Fiber-reinforced restoration intact"
      ],
      color: "2E8B57"
    }
  ];

  cards.forEach((card, i) => {
    let x = 0.3 + i * 4.9;
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    s.addShape(pres.ShapeType.rect, { x, y: 2.2, w: 4.6, h: 0.5, fill: { color: card.color }, line: { type: "none" }, rounding: 0.1 });
    s.addText(card.title, { x: x + 0.15, y: 2.2, w: 4.3, h: 0.5, fontSize: 13, bold: true, color: TEXT_LIGHT, fontFace: "Calibri", valign: "middle" });
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    s.addText(bRows, { x: x + 0.18, y: 2.82, w: 4.2, h: 2.3, valign: "top" });
  });
}

// ─── SLIDE 16: SECTION – DISCUSSION ─────────────────────────────────────────
addSectionHeader("Discussion & Key Takeaways");

// ─── SLIDE 17: DISCUSSION ────────────────────────────────────────────────────
{
  let s = addSlide(LIGHT_BG);
  slideTitle(s, "Discussion — Biomimetic Concepts & Literature Context");

  const points = [
    {
      heading: "Why Polyethylene Fiber (Ribbond)?",
      text: "Acts as an internal splint — distributes stress across weakened dentin, limits crack propagation. Avoids aggressive post preparation that further weakens the root."
    },
    {
      heading: "Bio-Block / Bio-Bulk Concept (Fráter et al.)",
      text: "Short fiber-reinforced composite used to fill resorptive defects and restore biomechanical integrity. The present case adapts this concept conservatively."
    },
    {
      heading: "Bioceramic Sealer (BioRoot RCS)",
      text: "Provides satisfactory adaptation within the irregular, balloon-shaped canal anatomy characteristic of IIR. Calcium silicate chemistry ensures biocompatibility."
    },
    {
      heading: "Histopathologic Correlation — Added Value",
      text: "Provides biological confirmation of diagnosis. Multinucleated odontoclast-like cells + resorptive lacunae = definitive evidence of IIR. Rarely documented in routine clinical reports."
    },
    {
      heading: "CBCT as Standard of Care",
      text: "ESE position statement supports CBCT in endodontics when conventional radiography is inadequate. Here it changed the management plan by confirming no perforation → orthograde approach."
    },
  ];

  points.forEach((p, i) => {
    let y = 0.72 + i * 0.96;
    s.addShape(pres.ShapeType.rect, { x: 0.3, y, w: 9.4, h: 0.88, fill: { color: i % 2 === 0 ? STRIPE : CARD_BG }, line: { color: ACCENT, pt: 0.5 }, rounding: 0.07 });
    s.addShape(pres.ShapeType.rect, { x: 0.3, y, w: 0.2, h: 0.88, fill: { color: ACCENT }, line: { type: "none" }, rounding: 0.07 });
    s.addText(p.heading, { x: 0.62, y: y + 0.05, w: 9.0, h: 0.33, fontSize: 11.5, bold: true, color: ACCENT, fontFace: "Calibri" });
    s.addText(p.text, { x: 0.62, y: y + 0.36, w: 8.9, h: 0.46, fontSize: 10.5, color: TEXT_DARK, fontFace: "Calibri", wrap: true });
  });
}

// ─── SLIDE 18: LIMITATIONS & CRITICAL APPRAISAL ──────────────────────────────
{
  let s = addSlide(LIGHT_BG);
  slideTitle(s, "Critical Appraisal — Strengths & Limitations");

  // Strengths
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  s.addShape(pres.ShapeType.rect, { x: 0.3, y: 0.72, w: 4.5, h: 0.5, fill: { color: ACCENT }, line: { type: "none" }, rounding: 0.1 });
  s.addText("✔  Strengths", { x: 0.45, y: 0.72, w: 4.2, h: 0.5, fontSize: 13, bold: true, color: TEXT_LIGHT, fontFace: "Calibri", valign: "middle" });
  const strengths = [
    "Multidisciplinary approach — endodontics + restorative + pathology",
    "CBCT used for accurate 3D diagnosis (ESE guideline–aligned)",
    "Histopathologic confirmation — adds scientific rigor",
    "Conservative approach — no post, minimal tissue sacrifice",
    "6-month radiographic + clinical follow-up documented",
    "Clear, step-by-step clinical description reproducible by clinicians",
  ];
  let sRows = strengths.map((t, i) => ({ text: t, options: { bullet: { code: "2714" }, color: ACCENT, fontSize: 11, fontFace: "Calibri", paraSpaceAfter: 8, breakLine: i < strengths.length - 1 } }));
  s.addText(sRows, { x: 0.45, y: 1.32, w: 4.25, h: 3.95, valign: "top" });

  // Limitations
  s.addShape(pres.ShapeType.rect, { x: 5.1, y: 0.72, w: 4.6, h: 4.65, fill: { color: "FFF4F4" }, line: { color: ACCENT2, pt: 1.5 }, rounding: 0.1 });
  s.addShape(pres.ShapeType.rect, { x: 5.1, y: 0.72, w: 4.6, h: 0.5, fill: { color: ACCENT2 }, line: { type: "none" }, rounding: 0.1 });
  s.addText("✖  Limitations", { x: 5.25, y: 0.72, w: 4.3, h: 0.5, fontSize: 13, bold: true, color: TEXT_LIGHT, fontFace: "Calibri", valign: "middle" });
  const limitations = [
    "Single case report — lowest level of evidence",
    "Short follow-up (6 months) — long-term durability unknown",
    "No control group or comparative data",
    "Fracture resistance not quantitatively measured",
    "Enamel chipping during access — technique-sensitive",
    "Larger RCTs needed to validate biomimetic reinforcement",
  ];
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  s.addText(lRows, { x: 5.25, y: 1.32, w: 4.35, h: 3.95, valign: "top" });
}

// ─── SLIDE 19: KEY TAKEAWAYS ─────────────────────────────────────────────────
{
  let s = addSlide(LIGHT_BG);
  slideTitle(s, "Key Takeaways for Clinical Practice");

  const takeaways = [
    { num: "01", text: "IIR can be clinically silent — routine radiographic screening is important, especially in patients with a history of dental trauma.", color: ACCENT },
    { num: "02", text: "CBCT should be the standard when 2D radiography cannot determine lesion extent or differentiate internal from external resorption.", color: ACCENT },
    { num: "03", text: "Histopathologic examination provides biological proof of IIR — consider sending extirpated tissue for analysis.", color: ACCENT },
    { num: "04", text: "Biomimetic reinforcement with polyethylene fiber (Ribbond) + fiber-reinforced composite offers a conservative alternative to post placement.", color: "2E8B57" },
    { num: "05", text: "Bioceramic sealers adapt well to irregular IIR canal anatomy — an advantage over conventional sealers.", color: "2E8B57" },
  ];

  takeaways.forEach((t, i) => {
    let y = 0.72 + i * 0.96;
    s.addShape(pres.ShapeType.rect, { x: 0.3, y, w: 9.4, h: 0.88, fill: { color: i % 2 === 0 ? STRIPE : CARD_BG }, line: { color: t.color, pt: 1 }, rounding: 0.08 });
    s.addShape(pres.ShapeType.rect, { x: 0.3, y, w: 0.7, h: 0.88, fill: { color: t.color }, line: { type: "none" }, rounding: 0.08 });
    s.addText(t.num, { x: 0.3, y, w: 0.7, h: 0.88, fontSize: 16, bold: true, color: TEXT_LIGHT, fontFace: "Calibri", align: "center", valign: "middle" });
    s.addText(t.text, { x: 1.1, y: y + 0.12, w: 8.45, h: 0.66, fontSize: 12, color: TEXT_DARK, fontFace: "Calibri", wrap: true, valign: "middle" });
  });
}

// ─── SLIDE 20: CONCLUSION ────────────────────────────────────────────────────
{
  let s = pres.addSlide();
  s.addShape(pres.ShapeType.rect, { x: 0, y: 0, w: 10, h: 5.625, fill: { color: DARK_BG }, line: { type: "none" } });
  s.addShape(pres.ShapeType.rect, { x: 0, y: 4.9, w: 10, h: 0.725, fill: { color: ACCENT }, line: { type: "none" } });
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  s.addText("CONCLUSION", { x: 0.65, y: 0.6, w: 9, h: 0.42, fontSize: 11, bold: true, color: ACCENT, fontFace: "Calibri", charSpacing: 3 });
  s.addText("A Clinically Useful Strategy for Structurally Compromised Teeth", {
    x: 0.65, y: 1.08, w: 9, h: 0.65, fontSize: 20, bold: true, color: TEXT_LIGHT, fontFace: "Calibri"
  });

  const concl = [
    "Internal inflammatory resorption may remain clinically silent despite progressive structural compromise.",
    "CBCT enables accurate diagnosis and guides treatment planning — key to avoiding unnecessary surgical intervention.",
    "Conservative nonsurgical RCT can arrest resorption; biomimetic reinforcement addresses the resultant structural weakness.",
    "This case demonstrates that CBCT assessment + histopathologic correlation + fiber-reinforced biomimetic rehabilitation is a clinically valid multidisciplinary strategy.",
    "Long-term RCTs are needed to confirm durability of polyethylene fiber reinforcement in IIR cases.",
  ];

  concl.forEach((c, i) => {
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  });

  s.addText("Thank You — Questions Welcome", { x: 0.4, y: 4.93, w: 9.2, h: 0.45, fontSize: 13, bold: true, color: TEXT_LIGHT, fontFace: "Calibri", align: "center", valign: "middle" });
}

// ─── SLIDE 21: REFERENCES ────────────────────────────────────────────────────
{
  let s = addSlide(LIGHT_BG);
  slideTitle(s, "References");

  const refs = [
    "1. Patel S, Ricucci D, Durak C, Tay F. Internal root resorption: A review. J Endod 2010;36:1107-21.",
    "2. Patel S, Saberi N. The ins and outs of root resorption. Br Dent J 2018;224:691-9.",
    "3. Patel S, Brown J, Semper M, Abella F, Mannocci F. ESE position statement: The use of CBCT in Endodontics. Int Endod J 2019;52:1675-8.",
    "4. Soares CJ, et al. How biomechanics can affect the endodontic treated teeth and their restorative procedures? Braz Oral Res 2018;32:e76.",
    "5. Garoushi S, et al. Short fiber-reinforced composite restorations: A review. J Investig Clin Dent 2018;9:e12330.",
    "6. Belli S, et al. The effect of fibre insertion on fracture resistance of endodontically treated molars. Int Endod J 2006;39:505-10.",
    "7. Deepika, Nagpal AK. Comparative evaluation of simulated perforating resorptive defects repaired using calcium-silicate cements. J Conserv Dent Endod 2025;28:972-6.",
    "8. Fráter M, et al. Bioblock technique to treat severe internal resorption with periapical pathology. Restor Dent Endod 2020;45:e43.",
    "9. Garoushi S, et al. Direct restoration of severely damaged incisors using short fibre-reinforced composite. Open Dent J 2013;7:169-72.",
  ];

  refs.forEach((r, i) => {
    let y = 0.72 + i * 0.52;
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  });
}

// Save
pres.writeFile({ fileName: "/home/daytona/workspace/journal-club-cbct/CBCT_Biomimetic_IIR_JournalClub.pptx" })
  .then(() => console.log("SAVED"))
  .catch(e => console.error(e));

cd /home/daytona/workspace/journal-club-cbct && node create_pptx.js 2>&1

ls -lh /home/daytona/workspace/journal-club-cbct/

ls -lh /home/daytona/workspace/journal-club-cbct/ && file /home/daytona/workspac…

cp /home/daytona/workspace/journal-club-cbct/CBCT_Biomimetic_IIR_JournalClub.ppt…

cd /home/daytona/workspace && libreoffice --headless --convert-to pdf journal-cl…

mkdir -p /home/daytona/workspace/output && libreoffice --headless --convert-to p…

chmod 777 /home/daytona/workspace/output && libreoffice --headless --convert-to …

ls -la /home/daytona/workspace/ && whoami && id

cp /home/daytona/workspace/CBCT_Biomimetic_IIR_JournalClub.pptx /home/daytona/CB…

libreoffice --headless --convert-to pdf /home/daytona/CBCT_Biomimetic_IIR_Journa…

cp /home/daytona/CBCT_Biomimetic_IIR_JournalClub.pdf /home/daytona/workspace/CBC…