What is the causes for DNS Recurrence even after septoplasty

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septoplasty AND revision

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persistent nasal obstruction after septoplasty causes nasal valve turbinate official patient information

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https://www.mayoclinic.org/medical-professionals/otolaryngol…

“DNS recurrence” after septoplasty may mean either the septum has become deviated again, or nasal blockage has persisted from another cause. Common reasons include:
  1. Residual deviation left at surgery
    • A posterior bony spur, high deviation, or caudal/anterior deviation may not have been fully corrected.
    • Persistent posterior septal spurs are a recognized reason for continued obstruction after septoplasty. Cummings Otolaryngology Head and Neck Surgery, section “Complications of Septoplasty.”
  2. Cartilage memory or healing-related shift
    • Septal cartilage can bend back toward its original shape, particularly in severe, S-shaped, caudal, or traumatic deviations.
    • Scar contraction during healing can also pull structures off-center.
  3. New trauma
    • Even a seemingly minor nasal injury after surgery can re-deviate the septum.
  4. Inferior turbinate enlargement
    • Turbinates can remain enlarged or enlarge again due to allergy, irritants, infection, or chronic rhinitis. A straight septum alone will not fix this. ENT Health notes that allergies and turbinate swelling commonly cause nasal blockage.
  5. Nasal valve narrowing or collapse
    • The narrowest portion of the nasal airway may collapse during inspiration, especially if support is weak or was affected by prior surgery. This can feel exactly like a deviated septum.
    • It is more likely if an external nasal strip noticeably improves breathing. Mayo Clinic describes assessment for persistent obstruction, including valve problems and altered cartilage support.
  6. Adhesions or scar bands
    • Internal scarring between the septum and turbinate/lateral nasal wall, called synechiae, can obstruct airflow.
  7. Inflammatory nasal disease
    • Allergic rhinitis, non-allergic rhinitis, chronic rhinosinusitis, nasal polyps, and medication-related congestion can cause ongoing blockage even with a corrected septum.
  8. Early postoperative swelling
    • If surgery was recent, swelling, crusting, and healing can mimic recurrence. Final airflow is often not judged until healing has progressed over several weeks to months.
  9. Mismatch between the visible anatomy and symptoms
    • Nasal obstruction is partly subjective and can vary with the normal nasal cycle, seasons, allergies, and sleep position. A small residual bend is not always the actual cause of symptoms.
What to do: Get reassessed by an ENT, ideally with nasal endoscopy. They can distinguish residual/recurrent septal deviation from turbinate hypertrophy, scar tissue, sinus disease, and nasal valve collapse. Medical treatment for inflammation or allergy may be enough; revision septoplasty, turbinate treatment, or functional rhinoplasty is considered only when a correctable structural cause is confirmed.
Seek earlier review for persistent heavy bleeding, worsening pain/swelling, fever, foul discharge, a new change in nasal shape, or a blocked nose on both sides soon after surgery.

How long should I wait before considering revision septoplasty?

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septoplasty AND revision

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revision septoplasty wait 6 months healing ENT

In most cases, wait at least 6 months after the original septoplasty before deciding on revision surgery. Many ENT surgeons prefer 9-12 months when there is substantial swelling, scarring, altered nasal shape, or possible nasal-valve surgery, because tissues and cartilage need time to settle.
A practical timeline:
  • 0-6 weeks: blockage is often from swelling, crusts, splints, or healing. Do not judge the final result yet.
  • 6 weeks to 3 months: your ENT can assess healing and treat contributors such as allergies, turbinate swelling, infection, or adhesions.
  • 3-6 months: persistent, clearly documented obstruction warrants a detailed reassessment, often including nasal endoscopy and evaluation for nasal-valve collapse.
  • 6-12 months: usual window to consider revision if symptoms remain significant despite healing and appropriate medical treatment, and an anatomical cause is found.
Do not wait for a routine revision decision if you develop severe worsening obstruction, fever, increasing pain, foul discharge, recurrent significant bleeding, a visible new nasal deformity, or suspected septal hematoma/abscess. These need prompt ENT review.
A revision should be based on what is actually causing the blockage, not only the impression that the DNS has recurred. Common overlooked causes include a residual posterior bony spur, turbinate hypertrophy from allergy/rhinitis, scar adhesions, and nasal-valve narrowing or collapse. Persistent obstruction is the most common reported complaint after septoplasty, and residual posterior septal spurs can be relevant. Cummings Otolaryngology Head and Neck Surgery, “Complications of Septoplasty.”
Recent systematic reviews support that septoplasty can improve obstruction overall, but they do not establish a single universal timing rule for revision, so the decision should be individualized with an ENT examination (2025 systematic review).

What tests can confirm the cause of persistent blockage?

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nasal obstruction AND rhinomanometry

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persistent nasal obstruction after septoplasty nasal endoscopy rhinomanometry acoustic rhinometry evaluation

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https://www.mayoclinic.org/medical-professionals/otolaryngol…

The most useful evaluation is an ENT examination with nasal endoscopy. No single test confirms every cause, so the diagnosis usually combines examination, a trial of decongestant, and selected objective tests.
Test / assessmentWhat it can identify
History and symptom scoringWhether blockage is one-sided or both, constant or intermittent, allergy-related, sleep-related, or triggered by exercise. The validated NOSE score measures how severe nasal-obstruction symptoms are and can compare before and after treatment.
External nasal examination + anterior rhinoscopyResidual/recurrent septal deviation, caudal septal deviation, septal perforation, scar bands, visible turbinate enlargement, and external nostril narrowing.
Nasal endoscopyUsually the key test after septoplasty. A thin camera examines the posterior septum for an untreated bony spur, synechiae (scar adhesions), turbinate hypertrophy, polyps, sinus drainage/inflammation, infection, and deeper obstruction. Mayo Clinic explains nasal endoscopy.
Before-and-after decongestant examinationThe ENT examines or measures airflow before and after a topical decongestant. Clear improvement suggests swelling of the lining/turbinates from rhinitis or allergy. Little improvement suggests a fixed structural issue, such as residual deviation, scar, or valve narrowing. Scott-Brown's Otorhinolaryngology Head & Neck Surgery, Vol. 1, p. 1184.
Nasal-valve assessmentInspection while breathing in, plus modified Cottle or Bachmann maneuvers. If gently supporting a particular part of the nasal sidewall improves airflow, nasal-valve narrowing/collapse may contribute. A trial of external nasal dilator strips can also be informative. Mayo Clinic describes these maneuvers.
RhinomanometryMeasures airflow and pressure during breathing to calculate nasal airway resistance. It provides an objective measure of obstruction, though results can vary with the normal nasal cycle.
Acoustic rhinometryUses reflected sound to estimate nasal cross-sectional area and cavity volume. It can help document a narrow area, but may miss dynamic nasal-valve collapse because it does not measure airflow during inspiration.
CT scan of nose/sinusesNot routinely needed for simple blockage. It is useful when endoscopy or symptoms suggest chronic sinusitis, polyps, a deep posterior bony deviation, prior trauma, unusual anatomy, or when planning revision surgery. It does not by itself diagnose dynamic valve collapse or allergy.
Allergy evaluationSkin-prick or blood-specific IgE testing can help if congestion fluctuates with seasons, dust, pets, or sneezing/itching/watery discharge. It identifies allergic triggers but does not prove that allergy is the only cause.
Culture or biopsy, rarelyUsed only if there is persistent purulent discharge, crusting, suspicious mass, or concern for infection or another disease.
A sensible order after septoplasty:
  1. ENT review with anterior examination and nasal endoscopy.
  2. Assess airflow before and after a decongestant.
  3. Check specifically for nasal-valve collapse.
  4. If the cause is still unclear or revision is being considered, consider rhinomanometry/acoustic rhinometry and a CT if sinus disease or complex anatomy is suspected.
Objective tests help document airflow, but they cannot replace the examination. Current ENT texts note that no technology reliably identifies every exact level or cause of obstruction, so clinical examination remains central. Scott-Brown's Otorhinolaryngology Head & Neck Surgery, Vol. 1, p. 1184.

Is this Recurrence is common?

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septoplasty AND revision

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septoplasty revision rate persistent nasal obstruction systematic review

True recurrence or need for revision is not common, but some persistent nasal blockage after septoplasty is not rare.
  • In a large US study of 295,236 patients, about 1.1% underwent revision septoplasty. That measures repeat surgery, so it likely underestimates people who still have symptoms but do not choose another operation. Large revision-rate study
  • A 2025 meta-analysis of randomized trials reported a revision rate of about 0.31%, with overall symptom improvement more apparent at 6 and 12 months. 2025 meta-analysis
  • Studies of outcomes report a wider range of “not fully relieved” symptoms, sometimes up to about 15%, because this includes all persistent blockage, not just an actual recurrent septal bend.
The distinction matters:
  • Actual septal re-deviation: relatively uncommon.
  • Persistent feeling of blockage: more frequent, and often due to something other than recurrence, such as turbinate swelling from rhinitis/allergy, residual posterior bony deviation, scar adhesions, or unrecognized nasal-valve collapse.
ENT texts list persistent septal deformity, intranasal scarring, and nasal-valve collapse among recognized causes of ongoing obstruction after septal surgery. K J Lee’s Essential Otolaryngology, “Postoperative Complications.”
If you are still within the first few months after surgery, swelling and healing can make it seem as though the deviation has returned. If blockage is still substantial after about 6 months, a targeted ENT assessment with endoscopy and nasal-valve evaluation is reasonable.
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Interpret

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Mayo Clinic CT sinus what it shows nasal septum sinus inflammation nasal obstruction

This is a single axial CT slice of the paranasal sinuses, viewed from below. Thus, the right side of the image is your left side and vice versa, as marked R and L.
What appears visible on this screenshot:
  • Maxillary sinuses: Both look largely air-filled and clear on this slice. I do not see obvious fluid levels or marked sinus opacification here.
  • Nasal septum: It does not look perfectly midline on this one image. There appears to be a mild residual deviation/irregularity, with relative narrowing of one nasal passage. However, its exact direction and severity cannot be reliably established from one screenshot.
  • Turbinates/nasal lining: There may be some turbinate prominence, but this needs assessment through the complete CT series and, more importantly, nasal endoscopy.
  • No obvious destructive bone lesion or large mass is apparent on this one image.

Important limitation

This image cannot by itself confirm recurrent DNS or explain persistent blockage. Septal deviation, especially the front/caudal part, posterior bony spurs, scar adhesions, and dynamic nasal-valve collapse can be missed or underappreciated on a single axial slice. The full CT in axial, coronal, and sagittal planes plus an ENT endoscopic examination is needed.
For your symptoms after septoplasty, ask the ENT/radiologist specifically to comment on:
  1. Residual or recurrent septal deviation, including caudal and posterior bony spur
  2. Inferior turbinate hypertrophy
  3. Synechiae, meaning internal scar bands
  4. Nasal-valve narrowing/collapse
  5. Sinus drainage-pathway blockage or chronic sinus inflammation
CT helps delineate septal deviation and sinonasal disease, but clinical examination remains necessary to identify the actual cause of nasal obstruction. Scott-Brown's Otorhinolaryngology Head & Neck Surgery, Vol. 1, “Imaging.”

Tpo elevated due to

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thyroid peroxidase antibodies AND thyroiditis

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thyroid peroxidase TPO antibodies elevated causes Hashimoto Graves American Thyroid Association

If by TPO you mean anti-thyroid peroxidase antibody (anti-TPO / TPOAb), elevation usually means the immune system is reacting against thyroid tissue.

Most common cause

  • Hashimoto’s thyroiditis: the commonest cause. It may eventually cause an underactive thyroid, but TSH and free T4 can still be normal early on.

Other possible causes

  • Graves’ disease, an autoimmune cause of overactive thyroid
  • Postpartum thyroiditis or painless/silent thyroiditis
  • Less commonly, other autoimmune conditions can coexist
  • Sometimes it is positive in people with normal thyroid function who may never develop overt thyroid disease
A high TPO antibody level does not itself tell whether thyroid hormone is low or high, and the number does not reliably reflect severity. Interpret it with:
  • TSH: most important
  • Free T4, sometimes Free T3
  • Thyroglobulin antibody (TgAb)
  • Thyroid ultrasound only if there is enlargement, a lump/nodule, pain, or an uncertain diagnosis
Typical interpretation:
ResultUsual meaning
TPO high + TSH normal + free T4 normalThyroid autoimmunity with normal function. Monitor TSH periodically.
TPO high + TSH high + free T4 low/normalHashimoto-related hypothyroidism or subclinical hypothyroidism.
TPO high + TSH low + free T4/T3 highCould be Graves’ disease or a thyroiditis. Check TSH-receptor antibodies/TRAb to help distinguish.
TPO antibodies are a marker of autoimmune thyroid disease, particularly Hashimoto’s thyroiditis and sometimes Graves’ disease, as explained by the American Thyroid Association.
If you share the TPO value with lab range, TSH, free T4, and symptoms, I can explain the pattern more specifically.

Treatment for hashimoto

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Hashimoto disease AND levothyroxine

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American Thyroid Association Hashimoto thyroiditis treatment levothyroxine TSH monitoring

Treatment depends on your TSH and free T4, not the TPO antibody level alone.
Thyroid testsUsual approach
TPO high, TSH and free T4 normalNo thyroid hormone treatment is usually needed. Check TSH once or twice yearly. Repeating TPO antibody levels is generally not useful.
TSH mildly high, free T4 normal: subclinical hypothyroidismTreatment may or may not be needed. It depends on TSH level, symptoms, age, TPO positivity, goiter, cholesterol/cardiac risk, and plans for pregnancy. Your clinician may monitor or start levothyroxine.
TSH high, free T4 low: overt hypothyroidismLevothyroxine (synthetic T4) is standard treatment, usually long term. Dose is individualized and adjusted according to TSH.

Levothyroxine basics

  • Take it on an empty stomach with water, consistently at the same time daily, usually 30-60 minutes before breakfast.
  • Separate it from iron, calcium, antacids, and multivitamins by at least 4 hours, because they can reduce absorption.
  • TSH is usually rechecked about 6-8 weeks after starting or changing dose. Once stable, it is commonly checked every 6-12 months.
  • Do not change the dose or stop the medication on your own.

What is not routinely recommended

  • Treating an elevated TPO antibody alone with thyroid hormone when TSH and free T4 are normal.
  • Using T3 or desiccated thyroid routinely instead of levothyroxine.
  • High-dose iodine or selenium supplements without clinician advice. Excess iodine can worsen autoimmune thyroid disease. Selenium is not a standard substitute for hormone replacement.

Pregnancy or planning pregnancy

Tell your doctor early. Thyroid targets and monitoring are stricter in pregnancy, and levothyroxine needs often increase. Do not wait for symptoms if you are pregnant or trying to conceive.
The American Thyroid Association guidance states that antibody-positive people with normal TSH and free T4 usually need monitoring rather than treatment, while clinical hypothyroidism is treated with levothyroxine.

35 years male with elevated tsh and tpo with normal free t4, what is the diagnosis and management

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subclinical hypothyroidism AND levothyroxine

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subclinical hypothyroidism management TSH 10 positive TPO guideline adults

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Likely diagnosis

This pattern is most consistent with subclinical hypothyroidism due to autoimmune thyroiditis (Hashimoto’s thyroiditis):
  • Elevated TSH means the pituitary is working harder to stimulate the thyroid.
  • Normal free T4 means thyroid hormone production is still adequate.
  • Elevated anti-TPO antibody supports an autoimmune cause, most often Hashimoto’s.
It is not yet overt hypothyroidism, but TPO positivity makes progression more likely. Scott-Brown's Otorhinolaryngology Head & Neck Surgery, p. 785, notes that elevated TSH plus thyroid autoantibodies carries an approximately 5% yearly risk of progression to overt hypothyroidism.

Management for a 35-year-old man

1. Confirm and assess

  • Repeat TSH and free T4 in about 2-3 months if this is a first abnormal result, especially if TSH is only mildly raised.
  • Review symptoms: fatigue, cold intolerance, constipation, dry skin, weight gain, low mood, hair loss, reduced exercise tolerance, libido/sexual-function changes.
  • Review medicines and factors that can affect TSH, including amiodarone, lithium, iodine-containing supplements, and recent acute illness.
  • Check a lipid profile and cardiovascular risk factors.
  • Do not repeatedly measure TPO antibodies. Once positive, following TSH and free T4 is more useful.
  • Thyroid ultrasound is not routinely required. Use it if there is thyroid enlargement, a lump/nodule, asymmetry, neck pressure, hoarseness, or trouble swallowing.

2. Decide on levothyroxine based mainly on TSH

TSH patternUsual approach
TSH ≥10 mIU/L, confirmed on repeat testingUsually start levothyroxine, unless there is a specific reason not to.
TSH above lab range but <10 mIU/LIndividualize. At age 35, a 6-month monitored trial of levothyroxine is reasonable to discuss if there are hypothyroid symptoms, positive TPO antibodies, goiter, progressively rising TSH, high cholesterol, or relevant cardiovascular risk.
Mildly elevated TSH, no symptoms, stable resultMonitoring without medicine is reasonable, but because TPO is positive, check TSH and free T4 annually.
NICE recommends considering levothyroxine when TSH is at least 10 mIU/L on two tests 3 months apart. For adults under 65 with persistent TSH elevation below 10, a trial can be considered based on symptoms and features of underlying thyroid disease such as positive antibodies. NICE recommendations

3. If levothyroxine is started

  • The prescriber chooses the dose based on TSH level, body weight, symptoms, cardiac history, and other medicines. In mild/subclinical cases, treatment often begins with a lower dose and is adjusted, rather than automatically using a full replacement dose.
  • Take it consistently on an empty stomach with water, typically 30-60 minutes before breakfast.
  • Keep calcium, iron, antacids, and multivitamins at least 4 hours apart from it.
  • Recheck TSH about 6-8 weeks after starting or changing a dose.
  • Aim for a TSH in the laboratory reference range. Avoid overtreatment, which can cause palpitations, tremor, anxiety, and long-term bone/heart risks.

4. Avoid unproven approaches

  • Do not take high-dose iodine or “thyroid support” products. Excess iodine can aggravate autoimmune thyroid disease.
  • Selenium is not a replacement for levothyroxine and should not be self-prescribed at high doses.
  • Surgery is not a standard treatment for Hashimoto’s unless there is a suspicious nodule, major goiter with compression, or another specific surgical indication.
The exact next decision depends most on the actual TSH value. If you provide the TSH number, reference range, free T4 value, symptoms, and whether this result has been repeated, I can place you in the appropriate management group.

Create a Hashimoto’s monitoring plan

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Hashimoto disease AND monitoring

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Hashimoto thyroiditis monitoring TSH free T4 positive TPO annual American Thyroid Association NICE

Hashimoto’s Monitoring Plan

For: 35-year-old man with elevated TSH, positive TPO antibodies, and normal free T4
This is usually subclinical hypothyroidism due to Hashimoto’s thyroiditis.

Now: baseline review

Arrange a primary-care or endocrinology review with:
  • Repeat TSH and free T4 to confirm the pattern if this was the first abnormal test.
  • Record symptoms: fatigue, cold intolerance, constipation, dry skin, weight change, low mood, hair loss, reduced libido, muscle aches.
  • Physical examination for thyroid enlargement, asymmetry, nodules, or neck pressure.
  • Lipid profile and routine cardiovascular-risk assessment.
  • Review medicines/supplements, especially lithium, amiodarone, iodine-containing products, biotin, and “thyroid support” supplements.
  • Consider thyroid ultrasound only if there is a goiter, lump/nodule, asymmetry, persistent neck discomfort, swallowing difficulty, hoarseness, or abnormal examination. It is not needed routinely.
Do not keep rechecking TPO antibody levels. TPO establishes autoimmune thyroid disease, but changes in its value do not guide treatment.

Blood-test schedule

SituationTSH and free T4 monitoring
First abnormal result, TSH <10 mIU/LRepeat in 2-3 months to confirm persistence
Confirmed subclinical hypothyroidism, no medicationEvery 6-12 months. Given positive TPO, yearly testing at minimum is sensible
New or worsening hypothyroid symptomsTest earlier, rather than waiting for the scheduled check
Start or change levothyroxineRecheck TSH in 6-8 weeks
Stable on levothyroxineTSH every 6-12 months, and 6-8 weeks after any dose, major weight, or interacting-medication change
The American Thyroid Association advises checking TSH once or twice yearly in mild Hashimoto-related thyroid dysfunction and does not recommend serial TPO antibody monitoring. ATA Hashimoto guidance

Treatment decision points

1. TSH remains mildly high but is below 10 mIU/L

Discuss either observation or a monitored 6-month trial of levothyroxine if one or more of the following apply:
  • Symptoms compatible with hypothyroidism
  • TSH is rising over time
  • TPO antibodies are positive
  • Goiter
  • High LDL cholesterol or significant cardiovascular risk
  • Strong preference after discussing uncertain symptom benefit
If treatment is not started, continue the yearly TSH/free T4 plan.

2. TSH is 10 mIU/L or higher

If confirmed on repeat testing, levothyroxine is generally recommended, particularly in a young adult with positive TPO antibodies. NICE guidance recommends considering treatment when TSH is at least 10 mIU/L on two tests about 3 months apart.

3. Free T4 becomes low

This indicates overt primary hypothyroidism. Start levothyroxine under clinician supervision rather than continuing observation.

If levothyroxine is prescribed

  1. Take it at the same time every day, with water, on an empty stomach.
  2. Take it 30-60 minutes before food, or at bedtime at least 3-4 hours after the evening meal.
  3. Keep calcium, iron, antacids, multivitamins, and some cholesterol medicines at least 4 hours apart.
  4. Do not alter the dose based only on symptoms or antibody levels.
  5. Dose adjustments should be based primarily on TSH after 6-8 weeks.
The aim is a TSH within the laboratory reference interval, not a suppressed TSH. Too much hormone can cause palpitations, anxiety, tremor, and longer-term bone or heart effects.

What to track between visits

Keep a simple monthly note of:
  • Energy, sleep, mood, bowel pattern
  • Weight trend
  • Cold sensitivity and skin/hair changes
  • Resting heart rate or palpitations
  • New neck swelling, pain, swallowing symptoms, or voice change
  • Adherence to any levothyroxine and timing with supplements

Seek an earlier review if

  • Rapidly increasing fatigue, marked constipation, swelling, or unexplained weight gain
  • Persistent palpitations, tremor, heat intolerance, or unexplained weight loss
  • New thyroid swelling, neck lump, trouble swallowing, breathlessness when lying flat, or persistent hoarseness
  • TSH rises to 10 mIU/L or above
  • Free T4 becomes low
Avoid: high-dose iodine, kelp products, and unregulated thyroid supplements. These can worsen autoimmune thyroid dysfunction or interfere with testing.

Sign and symptoms of hashimoto

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Hashimoto disease AND symptoms

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Hashimoto thyroiditis symptoms signs American Thyroid Association

Hashimoto’s thyroiditis often develops slowly. Early on, many people have no symptoms, even with elevated TPO antibodies.
As thyroid hormone production falls and hypothyroidism develops, common symptoms include:

Common symptoms

  • Tiredness, low energy, excessive sleepiness
  • Feeling unusually cold
  • Weight gain or difficulty losing weight
  • Constipation
  • Dry, coarse skin
  • Hair thinning or hair loss, brittle nails
  • Puffy face or swelling around the eyes
  • Brain fog, poor concentration, slowed thinking
  • Low mood or depression
  • Muscle aches, joint pains, cramps, weakness
  • Reduced exercise tolerance
  • Hoarse voice
  • Reduced libido or erectile difficulties in men

Signs a clinician may find

  • Goiter: enlarged, firm thyroid gland in the front of the neck
  • Slow pulse
  • Dry/cool skin
  • Puffiness
  • Slowed reflexes
  • High cholesterol
  • In more advanced disease, anemia or low sodium can occur

Neck-related symptoms

The thyroid can enlarge and cause:
  • Neck fullness or pressure
  • Discomfort when wearing a collar
  • Difficulty swallowing
  • Rarely, breathlessness or persistent hoarseness

In your current pattern

With high TSH, positive TPO, and normal free T4, symptoms may be mild or absent. This is called subclinical hypothyroidism. Symptoms alone cannot confirm that Hashimoto’s is the cause, because fatigue, weight change, hair loss, and low mood are common for many other reasons.
The American Thyroid Association’s Hashimoto overview lists fatigue, weight gain, constipation, cold sensitivity, dry skin, depression, muscle aches, and reduced exercise tolerance as typical symptoms when hypothyroidism develops.
Seek medical review sooner if you have a rapidly enlarging neck lump, trouble swallowing or breathing, or persistent hoarseness.
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