Create a clerking diagnostic approach template for a lump/mass
e.g., "A swelling in the right side of my neck for 3 weeks"
| Feature | Questions to Ask |
|---|---|
| Site | Exact anatomical location; surface marking |
| Size | Approximate dimensions (cm); has it changed? |
| Shape | Round, oval, irregular, lobulated |
| Surface | Smooth, nodular, irregular |
| Edge/Margin | Well-defined (encapsulated) vs. ill-defined (infiltrative) |
| Consistency | Soft, firm, hard, rubbery, fluctuant, bony-hard |
| Colour | Overlying skin — normal, erythematous, blue-black |
| Tenderness | Tender on palpation? Spontaneously painful? |
| Temperature | Warm to touch? |
| System | Key Questions |
|---|---|
| General | Weight loss, appetite, fatigue, fever |
| Skin | Prior skin lesions, sun exposure, pigmented lesions (melanoma) |
| Breast | Nipple discharge, skin changes, prior biopsies |
| GI | Change in bowel habit, rectal bleeding, dysphagia |
| GU | Haematuria, testicular swelling |
| Resp | Haemoptysis, cough, dyspnoea |
| Lymphatic | Other lumps elsewhere (generalised lymphadenopathy) |
| Endocrine | Thyroid symptoms (heat/cold intolerance, palpitations, weight change) |
| Region | Key Test |
|---|---|
| Neck | Swallowing (thyroid), tongue protrusion (thyroglossal), CN assessment |
| Groin | Cough impulse, above/below inguinal ligament, reducibility |
| Scrotum | Transillumination, get above it (inguinal extension?), separate from testis |
| Breast | Skin tethering, nipple inversion, peau d'orange, axillary nodes |
| Abdomen | Percussion for resonance/dullness, bimanual palpation (kidney), Murphy's sign |
| Limb/Soft tissue | Tinel's sign, neurovascular distal exam |
| Category | Examples |
|---|---|
| Vascular | Haemangioma, AVM, aneurysm, lymphangioma |
| Infective/Inflammatory | Abscess, lymphadenitis, TB, cat-scratch, sarcoid |
| Traumatic | Haematoma, seroma, foreign body granuloma |
| Autoimmune | Rheumatoid nodule, SLE, Sjögren's (parotid) |
| Metabolic/Congenital | Lipoma, cyst (dermoid, sebaceous, thyroglossal, branchial) |
| Idiopathic | Fibrous histiocytoma |
| Neoplastic — Benign | Lipoma, fibroma, neurofibroma, leiomyoma |
| Neoplastic — Malignant | Primary sarcoma, SCC, BCC, metastasis, lymphoma |
| Congenital | Branchial cyst, thyroglossal cyst, dermoid, teratoma |
| Degenerative | Ganglion (joint degeneration) |
| Test | Rationale |
|---|---|
| FBC + differential | Anaemia, leucocytosis, lymphocytosis (lymphoma/leukaemia) |
| ESR / CRP | Inflammatory / infective process |
| LFTs, LDH | Hepatic metastases; LDH raised in lymphoma |
| TFTs | Thyroid mass |
| Ca²⁺, ACE | Sarcoidosis |
| Tumour markers | CEA, AFP, β-hCG, PSA, CA-125, CA19-9 (context-dependent) |
| HIV serology | Immunosuppressed states |
| Modality | Use |
|---|---|
| USS | First-line for superficial lumps; cystic vs. solid; Doppler for vascularity |
| CT chest/abdomen/pelvis | Staging; lymphadenopathy; deep masses |
| MRI | Soft-tissue characterisation (soft tissue sarcoma, spinal involvement) |
| PET-CT | Metabolic activity; occult primary; lymphoma staging |
| Mammography / breast USS | Breast lump ≥35 years |
| Plain X-ray | Calcification; bony involvement; chest (mediastinal mass) |
| Procedure | Indication |
|---|---|
| FNAC (Fine Needle Aspiration Cytology) | Quick; cysts, lymph nodes, thyroid |
| Core needle biopsy | Histological architecture; soft tissue tumours |
| Incisional biopsy | Large, deep tumours where core is non-diagnostic |
| Excisional biopsy | Small (<2 cm), easily accessible; diagnostic + therapeutic |
| Sentinel node biopsy | Staging of melanoma, breast cancer |
⚠️ Key rule: Do NOT incise a pulsatile mass before imaging — risk of catastrophic haemorrhage from aneurysm.