Emergency Procedures: Clinical Quick Reference
1. CARDIAC ARREST
Definition
Cessation of effective cardiac output - either asystole, ventricular fibrillation (VF), pulseless ventricular tachycardia (VT), or pulseless electrical activity (PEA/electromechanical dissociation).
Diagnosis
- Sudden loss of consciousness (occasionally with convulsions)
- Absent femoral or carotid pulse (confirm within 10-15 seconds)
- Apnea or agonal gasping
- Pallor/cyanosis/skin blotching
- Dilated pupils (unless patient is on opiates)
Common Causes
- Myocardial infarction (VF or PEA)
- Hypoxia (most common cause in surgical patients - airway obstruction, hypovolemia, acidosis)
- Electrolyte imbalance (hyperkalaemia - diastolic arrest or VF)
- Drug toxicity (adrenaline, potassium, calcium, halothane combination)
- Cardiac tamponade
- Hypothermia
- Pulmonary or air embolism
- Tension pneumothorax
- Anaphylaxis
- Drowning / electrocution
Treatment Steps
Step 1 - Call for help immediately
- Activate the cardiac arrest team (in-hospital: emergency code call)
- Note the time of arrest
Step 2 - Position and airway
- Lay patient supine on a firm surface; remove pillows
- Quickly check and clear the upper airway (dentures, food bolus, vomit)
- Head-tilt / chin-lift to open the airway
Step 3 - Precordial thump
- One firm thump with the ulnar border of a clenched fist to the lower sternum (may restart asystole)
Step 4 - Chest compressions (CPR)
- Heel of hand on the lower third of the sternum, other hand on top, arms straight
- Sharp, jerky downward compressions - aim to depress sternum 4-5 cm
- Rate: approximately 100 compressions/minute (once per second)
- If alone: 30 compressions : 2 rescue breaths; if team available, continue compressions uninterrupted while airway is managed separately
- One ventilation per 8 compressions (once intubated, do not pause for ventilation)
Step 5 - Ventilation
- If untrained or alone: mouth-to-nose or mouth-to-mouth resuscitation (12-15 breaths/min)
- Preferred: endotracheal intubation (8-9 mm tube for average adult), inflate cuff, connect reservoir bag with oxygen (100%)
- Confirm ETT position: bilateral chest rise, auscultation, ETCO2 if available
- If intubation not immediately possible: tight-fitting face mask + bag-valve-mask with IPPV
Step 6 - IV access
- Large-bore IV x 2; if veins collapsed, cut-down at antecubital fossa or central line (subclavian/internal jugular)
- Give sodium bicarbonate 200 mL of 4.2% IV to counter metabolic acidosis
- Elevate the legs
Step 7 - ECG diagnosis and defibrillation
- Connect ECG monitor (often incorporated in defibrillator)
- Identify rhythm: VF/pulseless VT → immediate defibrillation; Asystole/PEA → drugs + CPR
| Rhythm | Action |
|---|
| VF / Pulseless VT | Defibrillate 200J (monophasic) or 120-200J (biphasic); resume CPR immediately for 2 min; re-check rhythm |
| Asystole | Adrenaline (epinephrine) 1 mg IV every 3-5 min + CPR; consider atropine 3 mg IV (single dose) |
| PEA | Treat reversible causes (4 Hs & 4 Ts); adrenaline 1 mg IV every 3-5 min |
Step 8 - Drug therapy
- Adrenaline (epinephrine): 1 mg IV (1 mL of 1:1000 or 10 mL of 1:10,000) every 3-5 min - universal agent for all rhythms
- Amiodarone: 300 mg IV bolus for refractory VF (after 3rd shock); repeat 150 mg if VF recurs
- Lignocaine (lidocaine): 1 mg/kg IV if amiodarone unavailable
- Bicarbonate: 50 mL of 8.4% solution for severe metabolic acidosis or hyperkalaemia
- Calcium chloride: 10 mL of 10% for hyperkalaemia or hypocalcaemia
- Atropine: no longer routinely recommended for asystole/PEA in 2015 ALS guidelines
Step 9 - Post-resuscitation care
- If unconscious after ROSC: targeted temperature management (TTM) - cool to 32-36°C using ice packs/cooling blanket
- Chlorpromazine 12.5 mg IV may assist cooling
- Urinary output: give mannitol 500 mL of 10% IV to reduce cerebral oedema
- Dexamethasone 4-6 mg IM every 4 hours for 24 h (cerebral oedema, controversial)
- ICU admission; identify and treat precipitant
Step 10 - Internal (open) cardiac massage - when external CPR fails or in specific settings
- Indicated in: intrathoracic operation, cardiac tamponade from penetrating wound, air embolism, bilateral pneumothorax
- Fourth or fifth left intercostal space incision; extend from lateral sternal border to posterior axillary line; direct massage of the heart
(Pye's Surgical Handicraft, 22nd Ed.; Morgan & Mikhail's Clinical Anesthesiology, 7th Ed.)
2. ANAPHYLAXIS
Definition
Severe, life-threatening systemic hypersensitivity reaction with multi-organ involvement.
Diagnosis Criteria (any one):
- Sudden onset illness with skin/mucosal symptoms PLUS respiratory compromise OR hypotension/end-organ dysfunction
- OR two or more of: skin/mucosal changes, respiratory compromise, hypotension, GI symptoms - after exposure to likely allergen
- Or hypotension alone after known allergen exposure
Common Triggers
Drugs (penicillin, contrast, NSAIDs), insect stings, foods (nuts, shellfish, dairy), latex, exercise, idiopathic
Treatment Steps
Step 1 - Immediate assessment
- Airway-Breathing-Circulation evaluation
- Vital signs, pulse oximetry
- Assess for angioedema (uvular edema, stridor, hoarseness, respiratory distress)
- Call for help; lay patient supine (Trendelenburg if hypotensive)
Step 2 - Epinephrine (first-line - no absolute contraindications)
- Adult: Epinephrine 0.3-0.5 mg IM into the anterolateral thigh (vastus lateralis), using 1 mg/mL (1:1000) solution
- Child (<30 kg): Epinephrine 0.15 mg IM; use EpiPen Jr if available
- Child (dosing): 0.01 mg/kg IM, up to 0.5 mg per dose
- Repeat every 5-10 minutes if no improvement (most patients need only 1 dose)
- IM thigh preferred over deltoid - faster, higher, more consistent peak plasma levels than SC
- If cardiovascular collapse or refractory to 2-3 IM doses: IV epinephrine infusion (0.1-0.5 mcg/kg/min titrated to response); or IV bolus 0.1 mg of 1:10,000 solution slowly
- Auto-injectors: EpiPen (0.3 mg adult), EpiPen Jr (0.15 mg pediatric <30 kg)
Step 3 - Airway management
- High-flow O2 to maintain SpO2 >90%
- If angioedema is progressing and causing respiratory distress: early intubation (do not delay - complete obstruction can develop rapidly)
- Emergency surgical airway (cricothyroidotomy) if intubation fails
Step 4 - IV access and fluids
- Large-bore IV access
- 1-2 L isotonic crystalloid (NS or LR) for hypotension; 10-20 mL/kg bolus in children
- Repeat fluid boluses as needed; consider vasopressors (norepinephrine, dopamine) if refractory
Step 5 - Decontamination
- Remove causative agent if identifiable (remove stinger, stop IV drug infusion)
- Do NOT perform gastric lavage for food allergens
Step 6 - Bronchospasm management
- Nebulized salbutamol (albuterol) 2.5-5 mg for wheeze/bronchospasm
- Ipratropium bromide if bronchospasm refractory
- Inhaled beta-2 agonists are adjuncts, NOT replacements for epinephrine
Step 7 - Second-line agents (adjuncts - do NOT delay epinephrine for these)
- H1-antihistamine: Diphenhydramine 25-50 mg IV/IM (adults) - for urticaria and pruritus
- H2-antihistamine: Ranitidine 50 mg IV or famotidine 20 mg IV
- Corticosteroids: Methylprednisolone 1-2 mg/kg IV or hydrocortisone 200-300 mg IV (onset 4-6 h; reduce risk of biphasic reaction)
- Glucagon: 1-2 mg IV/IM for patients on beta-blockers who are refractory to epinephrine (beta-blockers block epinephrine's beta-receptor effects)
Step 8 - Observation
- Minimum 6 hours of observation after a severe reaction
- Patients with severe anaphylaxis or who received multiple epinephrine doses: observe 12-24 hours (biphasic anaphylaxis occurs in up to 20% of cases)
- Prescribe epinephrine autoinjector at discharge; educate on self-administration; refer to allergist
(Tintinalli's Emergency Medicine, 9th Ed.; ROSEN's Emergency Medicine; Washington Manual of Medical Therapeutics)
3. TYPES OF SHOCK
Shock = inadequate tissue oxygen delivery. Classified into four categories with different hemodynamic profiles and treatments.
3A. Hypovolemic / Hemorrhagic Shock
Causes: Trauma, GI bleed, burns, severe dehydration (vomiting, diarrhea)
Hemodynamics: Low CO, high SVR, low ScvO2
Treatment Steps
- Control hemorrhage: direct pressure, tourniquet, surgical intervention as appropriate
- IV access x 2 large-bore; send type & crossmatch, CBC, coagulation panel, lactate
- Fluid resuscitation with IV crystalloid (NS or LR) initially
- Target MAP 60-65 mmHg (permissive hypotension 50 mmHg acceptable in penetrating trauma until hemorrhage controlled)
- For hemorrhagic shock: packed red blood cells; massive transfusion protocol (pRBC:FFP:platelets in 1:1:1 ratio) for large volume losses
- Patients without major comorbidities can tolerate Hb ≥7 g/dL; do not over-transfuse
- Avoid overresuscitation - worsens dilutional coagulopathy, abdominal compartment syndrome
- Definitive surgical intervention for hemorrhage source control
3B. Distributive Shock (Septic)
Causes: Infection-driven vasodilation; also neurogenic, anaphylactic
Hemodynamics: Low SVR, high CO (often), low or high ScvO2; "warm shock"
Treatment Steps (Surviving Sepsis Campaign)
- Recognize early - qSOFA score (AMS, RR ≥22, SBP ≤100 mmHg)
- Blood cultures x 2 sets BEFORE antibiotics if delay <1 hour
- Broad-spectrum antibiotics within 1 hour of septic shock recognition (independent risk factor for mortality if delayed)
- IV crystalloid 30 mL/kg in first 3 hours
- Target MAP ≥65 mmHg
- If inadequate response to fluids: norepinephrine (first-line vasopressor) 0.01-0.5 mcg/kg/min IV; titrate to MAP goal
- Add vasopressin 0.03 units/min IV if norepinephrine requirements are high (reduces norepinephrine dose)
- Hydrocortisone 200-300 mg/day IV in refractory septic shock (vasopressor-dependent)
- Source control: drain abscesses, remove infected devices, surgical intervention as warranted
- Glucose management: target 140-180 mg/dL; avoid hypoglycemia
3C. Cardiogenic Shock
Causes: Acute MI (most common), acute mitral regurgitation, myocarditis, end-stage cardiomyopathy
Hemodynamics: Low CO, high SVR, high PCWP, decreased ScvO2; "cold shock"
Treatment Steps
- Identify and treat the underlying cause (emergent PCI for acute MI)
- Supplemental oxygen; NPPV (BiPAP) or intubation with mechanical ventilation reduces afterload and improves oxygenation; clears pulmonary edema
- Careful fluid management (avoid volume overload - worsens pulmonary edema)
- Inotropes: Dobutamine 2-20 mcg/kg/min IV (first-line inotrope); may add norepinephrine for hypotension
- Vasopressors: Norepinephrine or dopamine; avoid excess vasoconstriction
- Diuretics if volume-overloaded (furosemide IV)
- Intra-aortic balloon pump (IABP) or Impella device for mechanical circulatory support in refractory cases
- Cardiology consultation; consider emergent LVAD or heart transplant evaluation in refractory cases
3D. Obstructive Shock
Causes: Tension pneumothorax, cardiac tamponade, massive pulmonary embolism
Hemodynamics: Low CO, normal or high SVR; patient is preload-dependent but excessive fluids worsen RV overload
Treatment Steps
Tension Pneumothorax:
- Clinical diagnosis (do not wait for X-ray): tracheal deviation away from affected side, absent breath sounds, hypotension, distended neck veins
- Immediate needle thoracocentesis: 14-16G cannula, 2nd intercostal space, midclavicular line
- Definitive: chest tube (28-32 Fr) in 4th-5th intercostal space, anterior axillary line
Cardiac Tamponade:
- Beck's triad: hypotension + muffled heart sounds + distended neck veins; pulsus paradoxus >10 mmHg
- Confirm with bedside echo (pericardial effusion + RV collapse in diastole)
- Cautious IV fluid bolus to maintain preload
- Pericardiocentesis: subxiphoid approach, needle angled toward left shoulder, under echo guidance if possible; drain 15-20 mL for immediate hemodynamic improvement
- Surgical drainage for traumatic tamponade (thoracotomy)
Massive Pulmonary Embolism:
- Hemodynamic compromise + hypoxia + right heart strain (S1Q3T3, new RBBB, RV dilation on echo)
- High-flow O2; IV access
- Systemic thrombolysis: alteplase 100 mg IV over 2 hours (or 0.6 mg/kg over 15 min in cardiac arrest)
- Heparin anticoagulation: after thrombolysis is completed
- Surgical embolectomy or catheter-directed thrombolysis if systemic lysis is contraindicated
(Sabiston Textbook of Surgery; Washington Manual of Medical Therapeutics; Mulholland & Greenfield's Surgery)
4. ACUTE ISCHEMIC STROKE
Time is Brain - Goal: Door-to-needle ≤60 minutes
Diagnosis
- Sudden focal neurological deficits (face drooping, arm weakness, speech difficulty - FAST acronym)
- Assess with NIHSS (0-42 scale; higher = worse deficit)
- Non-contrast CT head STAT to exclude hemorrhagic stroke (mandatory before thrombolysis)
Treatment Steps
Step 1 - Prehospital and triage
- Prenotify stroke team before arrival
- Note time of symptom onset (or last known normal) precisely
- Transport directly to a stroke center with CT capability
Step 2 - Airway, breathing, circulation
- Supplemental O2 only if SpO2 <94%
- Correct hypoglycemia (glucose <60 mg/dL mimics stroke)
- IV access; do NOT give hypotonic fluids
Step 3 - Imaging
- Non-contrast CT head within 25 minutes of arrival
- CT angiography (CTA) to assess large vessel occlusion (LVO) if thrombectomy candidate
- MRI-DWI more sensitive but takes longer; use if CT equivocal
Step 4 - Systemic thrombolysis (IV tPA / alteplase)
- Indication: ischemic stroke within 4.5 hours of onset in eligible patients
- Dose: alteplase 0.9 mg/kg IV (maximum 90 mg); give 10% as bolus over 1 minute, remainder over 60 minutes
- Serum half-life: 4-10 minutes
- Contraindications: hemorrhagic stroke on CT, INR >1.7, active bleeding, recent surgery/trauma, platelet count <100,000, BP >185/110 mmHg (treat first)
- Tenecteplase (0.25 mg/kg IV bolus, max 25 mg) - alternative, easier single-bolus administration; non-inferior in some trials
- After tPA: no anticoagulants or antiplatelet agents for 24 hours; monitor in stroke unit
Step 5 - Mechanical thrombectomy
- Indication: large vessel occlusion (MCA, ICA, basilar), NIHSS ≥6, within 6 hours (up to 24 hours with favorable imaging/perfusion mismatch)
- Stent-retriever thrombectomy is the standard technique
- Can be performed even if tPA is given (bridging therapy) or if tPA is contraindicated
Step 6 - Blood pressure management
- Before thrombolysis: treat if BP >185/110 mmHg (labetalol 10-20 mg IV, nicardipine infusion)
- After thrombolysis: maintain BP <180/105 mmHg for 24 hours
- Without thrombolysis: permissive hypertension (allow up to 220/120 mmHg in first 24 h to maintain collateral flow)
Step 7 - Antiplatelet therapy
- Aspirin 325 mg orally or via NG tube within 24-48 hours of stroke onset (if no thrombolysis within preceding 24 h)
- For minor stroke/TIA: dual antiplatelet (aspirin + clopidogrel) for 21 days reduces recurrence
Step 8 - Anticoagulation
- Atrial fibrillation: initiate oral anticoagulation (DOAC or warfarin) for secondary prevention; timing depends on infarct size (usually 4-14 days post-stroke)
- Heparin is NOT routinely indicated for acute ischemic stroke
Step 9 - Supportive care
- Stroke unit admission
- Glucose: target 140-180 mg/dL (hyperglycemia worsens outcomes)
- Temperature: treat fever aggressively (paracetamol ± cooling)
- DVT prophylaxis: compression stockings; LMWH after 24-48 h if no hemorrhagic transformation
(Plum & Posner's Diagnosis and Treatment of Stupor and Coma; Miller's Anesthesia, 10th Ed.)
5. ACUTE MYOCARDIAL INFARCTION (STEMI)
Diagnosis
- Chest pain (pressure, radiation to jaw/arm/epigastrium)
- ST elevation ≥1 mm in 2 contiguous leads, or new LBBB
- Troponin elevation (may not be elevated in first hours - clinical + ECG diagnosis)
Treatment Steps
Step 1 - Immediate
- 12-lead ECG within 10 minutes of arrival
- Aspirin 300 mg chewed immediately (if not already on aspirin)
- Clopidogrel 600 mg loading dose OR ticagrelor 180 mg OR prasugrel 60 mg (P2Y12 inhibitor)
- IV access, O2 only if SpO2 <90%
- Morphine 2-4 mg IV for pain (titrate, but note: may impair antiplatelet absorption)
- Nitrates sublingually (GTN 0.4 mg SL); avoid if systolic BP <90 mmHg or if right ventricular infarction suspected
Step 2 - Reperfusion (the priority)
Primary PCI (preferred if available within 120 min of first medical contact):
- Activate cath lab immediately
- Unfractionated heparin (UFH) 60-70 units/kg IV bolus (max 5000 units) OR bivalirudin
- Door-to-balloon goal: ≤90 minutes
Thrombolysis (if primary PCI not available within 120 min):
- Tenecteplase (TNK-tPA) weight-based single IV bolus: 30 mg (<60 kg), 35 mg (60-70 kg), 40 mg (70-80 kg), 45 mg (80-90 kg), 50 mg (>90 kg)
- Streptokinase 1.5 million units IV over 60 min (older agent, less fibrin-specific)
- Antithrombins must accompany thrombolysis: enoxaparin or UFH
Step 3 - Adjunct therapy
- Beta-blockers (metoprolol succinate): within 24 hours if no contraindications (Killip Class I-II)
- ACE inhibitor (ramipril): within 24 hours, especially if LVEF <40%, anterior STEMI, hypertension, diabetes
- Statin: high-intensity (atorvastatin 80 mg) immediately
Step 4 - Monitoring and complications
- Continuous ECG monitoring (VT/VF risk highest in first 24-48 h)
- Reperfusion arrhythmias (accelerated idioventricular rhythm) are common and self-limiting
- Treat VF with defibrillation; sustained VT with amiodarone 150 mg IV or synchronized cardioversion
6. STATUS EPILEPTICUS
Definition
Seizure lasting >5 minutes, OR ≥2 seizures without full recovery of consciousness between them.
Treatment Steps (time-critical - follow the sequence)
0-5 min - Stabilize
- Lateral position (recovery position if possible); suction airway
- Supplemental oxygen; check blood glucose immediately (hypoglycemia is a common cause)
- IV access x 2; send: glucose, electrolytes, Ca/Mg, toxicology screen, AED levels, CBC
- If glucose <60 mg/dL: thiamine 100 mg IV THEN dextrose 50 mL of 50% IV
5-20 min - First-line: Benzodiazepines
- Lorazepam 4 mg IV (preferred; slower redistribution, longer duration) - may repeat once after 5-10 min if seizure continues
- If no IV: Diazepam 10 mg PR (rectal); or Midazolam 10 mg IM or intranasal (buccal)
- In children: Midazolam 0.2 mg/kg IM/IV/buccal; Lorazepam 0.1 mg/kg IV
20-40 min - Second-line (if benzodiazepines fail)
- Fosphenytoin 20 mg PE/kg IV at 150 mg PE/min (preferred; less hypotension/cardiac toxicity than phenytoin)
- OR Phenytoin 20 mg/kg IV at ≤50 mg/min (monitor ECG for PR prolongation, hypotension)
- OR Valproate 40 mg/kg IV over 10 minutes (preferred in absence epilepsy; avoid in pregnancy, liver disease, mitochondrial disease)
- OR Levetiracetam 60 mg/kg IV (max 4500 mg) - excellent safety profile, increasingly used first
40-60 min - Refractory status epilepticus: ICU + anaesthetic agent
- Intubation and mechanical ventilation required
- Propofol infusion 1-2 mg/kg IV loading, then 2-10 mg/kg/h
- OR Midazolam infusion 0.2 mg/kg IV loading, then 0.05-2 mg/kg/h
- OR Thiopentone (sodium thiopental) 3-5 mg/kg IV loading, then 3-5 mg/kg/h
- Continuous EEG monitoring mandatory; target burst-suppression pattern
- Treat precipitant: CNS infection (LP when safe), metabolic abnormality, AED non-compliance
7. DIABETIC EMERGENCIES
7A. Diabetic Ketoacidosis (DKA)
Diagnostic Criteria: Glucose >250 mg/dL (>13.9 mmol/L) + pH <7.3 OR bicarbonate <15 mEq/L + ketonemia/ketonuria
Treatment Steps
- IV access; send: ABG, BMP, ketones, urine ketones, CBC, cultures if infected
- Fluid resuscitation (highest priority): 1 L NS over 30-60 minutes; then 250-500 mL/h NS until hemodynamically stable; switch to 0.45% NaCl when glucose <250 mg/dL; add 5% dextrose when glucose <200 mg/dL
- Insulin: Regular insulin 0.1 units/kg/h IV infusion (do NOT give insulin before K+ is confirmed >3.5 mEq/L); target glucose fall of 50-75 mg/dL/h
- Potassium replacement (mandatory): DKA patients are total-body K+ depleted; replace if K+ <5.2 mEq/L
- Bicarbonate: only if pH <6.9 (50 mEq in 200 mL water over 2 h)
- Phosphate: replace if <1.0 mg/dL
- Monitor glucose hourly; electrolytes every 2-4 hours
- Identify and treat precipitant (infection, missed insulin, new diabetes)
- Transition to subcutaneous insulin when: pH >7.3, HCO3 ≥15, anion gap closed, patient eating
7B. Hyperosmolar Hyperglycemic State (HHS)
Diagnosis: Glucose >600 mg/dL, Osmolality >320 mOsm/kg, pH >7.3, minimal ketonemia
Treatment: Same priorities as DKA but fluid replacement is more aggressive (often 8-12 L deficit); insulin infusion started at lower rate after initial fluids; careful electrolyte monitoring
7C. Severe Hypoglycemia
Treatment
- If conscious and able to swallow: 15-20 g fast-acting oral glucose (glucose tablets, 150 mL fruit juice)
- If unconscious/unable to swallow:
- Dextrose 50 mL of 50% IV (D50W) followed by 100 mL D10W infusion
- Glucagon 1 mg IM or SC (if no IV access); glucagon 0.5 mg in children <25 kg
- Recheck blood glucose 15 minutes after treatment; repeat if still <70 mg/dL
- Once awake: carbohydrate-protein snack to prevent recurrence
- Identify cause: excess insulin, missed meal, renal failure, adrenal insufficiency, insulinoma
8. ACUTE RESPIRATORY FAILURE
Categories: Hypoxic (Type I) vs. Hypercapnic/Ventilatory (Type II)
Treatment Steps
Step 1 - Identify and classify
- ABG: PaO2 <60 mmHg on air = hypoxic failure; PaCO2 >45 mmHg = hypercapnic failure
- Pulse oximetry is not adequate alone - get ABG
Step 2 - Supplemental oxygen
- Controlled O2 via Venturi mask 24-28% (COPD/Type II - avoid high-flow O2 blunting hypoxic drive)
- Unrestricted high-flow O2 (non-rebreather mask 15 L/min) for Type I failure without hypercapnia
Step 3 - Non-invasive ventilation (NIV/NPPV) - try before intubation
- CPAP: for pulmonary edema, OSA-related respiratory failure, oxygenation failure
- BiPAP (IPAP/EPAP): for COPD exacerbation (Type II), neuromuscular disease, obesity hypoventilation
- Indications: RR >25, SpO2 <90% on high-flow O2, PaCO2 rising
- Contraindications: obtundation/unconsciousness, inability to protect airway, facial trauma, vomiting
Step 4 - Endotracheal intubation and mechanical ventilation
- Indications: GCS ≤8, failure of NIV, impending respiratory arrest, hemodynamic instability
- Rapid Sequence Intubation (RSI): Preoxygenate (5-10 min high-flow O2) → sedation + neuromuscular blockade → intubation
- Sedative: Ketamine 1-2 mg/kg IV (preferred in bronchospasm, hypotension) or etomidate 0.3 mg/kg IV
- Paralytic: Succinylcholine 1.5 mg/kg IV (contraindicated in hyperkalaemia, crush injuries >72h, burns); or Rocuronium 1.2 mg/kg IV
- Initial vent settings: FiO2 100% → wean; TV 6-8 mL/kg IBW (lung-protective); rate 12-20/min; PEEP 5-8 cmH2O
- Treat underlying cause: antibiotics (pneumonia), bronchodilators (COPD/asthma), diuretics (pulmonary edema)
9. HYPERTENSIVE EMERGENCY
Definition
Severely elevated BP (usually >180/120 mmHg) with acute end-organ damage (encephalopathy, stroke, acute MI, aortic dissection, acute kidney injury, eclampsia).
Distinguished from hypertensive urgency (severely elevated BP without organ damage - treat gradually over 24-48 h, oral medications).
Treatment Steps
- IV access; monitor BP continuously (arterial line preferred for severe cases)
- Identify end-organ damage: ECG, head CT, troponin, BMP, urinalysis with microscopy, fundoscopy
- Goal: reduce MAP by no more than 15-25% in the first hour (rapid reduction causes ischemic stroke, MI)
- Drug of choice depends on target organ:
| Presentation | Preferred Agent |
|---|
| Hypertensive encephalopathy | Labetalol IV or Nicardipine IV |
| Aortic dissection | Esmolol + Nitroprusside (target SBP ≤120 within 20 min) |
| Acute pulmonary edema | Nitroglycerin IV + loop diuretic |
| Acute MI / ACS | Nitroglycerin IV + beta-blocker |
| Acute kidney injury | Nicardipine IV or Fenoldopam IV |
| Eclampsia / Pre-eclampsia | Hydralazine IV or Labetalol IV + Magnesium sulfate (seizure prophylaxis) |
| Catecholamine excess (phaeochromocytoma) | Phentolamine IV (alpha-blocker FIRST; never beta-block alone) |
- Admit to ICU/monitored unit for continuous BP titration
(ROSEN's Emergency Medicine; Washington Manual of Medical Therapeutics)
10. TRAUMA EMERGENCIES
Primary Survey: ABCDE Approach (ATLS Protocol)
| Step | Assessment | Immediate Action |
|---|
| A - Airway | Obstruction, stridor | Jaw thrust, suction, ETT, surgical airway |
| B - Breathing | Tension pneumo, open chest | Needle decompression, chest tube, seal open wound |
| C - Circulation | Hemorrhage, pulse, BP | Direct pressure, IV access, blood products |
| D - Disability | GCS, pupils, FAST | Neurosurgery consult, ICP management |
| E - Exposure | Hidden injuries, hypothermia | Remove all clothing, warm blankets |
Massive Hemorrhage Control
- Direct pressure (do not remove packing - "scoop and run")
- Tourniquet: apply 2-3 cm above wound for limb hemorrhage; note time of application
- Pelvic binder for pelvic fracture with hemodynamic instability
- Permissive hypotension: target SBP 80-90 mmHg in penetrating trauma until OR
- Massive transfusion protocol: 1:1:1 (pRBC:FFP:platelets) + tranexamic acid 1 g IV within 3 hours of injury (reduces mortality)
- Damage control surgery: abbreviated surgical intervention to control hemorrhage and contamination; formal repair deferred until patient is resuscitated
Traumatic Brain Injury (TBI)
- Avoid hypotension (SBP <90 mmHg) and hypoxia (SpO2 <90%) - secondary brain injury drivers
- Head CT immediately after primary survey
- ICP monitoring if GCS ≤8 after resuscitation
- Elevate head of bed 30 degrees
- Target PaCO2 35-40 mmHg (mild hyperventilation only for acute herniation)
- Mannitol 0.25-1 g/kg IV or hypertonic saline 3% for elevated ICP
- Neurosurgical consultation for evacuable lesions (epidural hematoma, large SDH)
11. ACUTE ABDOMEN / SURGICAL EMERGENCIES
General Principles
- IV access, IV fluids, analgesia (do NOT withhold opioids pending diagnosis - does not mask the diagnosis)
- NPO, NG tube if vomiting
- Bloods: CBC, BMP, LFTs, amylase/lipase, coagulation, group & screen
- Imaging: plain X-ray (erect CXR for perforation), CT abdomen/pelvis with contrast
Key Surgical Emergencies
Perforated Viscus (peptic ulcer, colon)
- Erect CXR: free subdiaphragmatic air (present in 70%)
- Broad-spectrum antibiotics: ceftriaxone + metronidazole IV
- IV fluids resuscitation; insert urinary catheter
- Emergency laparotomy: peritoneal lavage + primary repair (omental patch for duodenal perforation)
Intestinal Obstruction
- NG tube (decompression)
- IV fluids + electrolyte correction
- Serial abdominal X-rays: step-ladder pattern (small bowel); haustra absent, grossly dilated colon
- CT with contrast: identifies level and etiology
- Strangulated obstruction: emergency surgery without delay
- Simple SBO (adhesions): initial non-operative management; surgery if no improvement in 24-48 h
Acute Appendicitis
- Clinical diagnosis (McBurney's point tenderness, Rovsing's, Psoas/obturator signs)
- USS or CT for confirmation (reduce CT dose in children - USS first)
- IV antibiotics (cefuroxime + metronidazole) - can resolve uncomplicated appendicitis
- Appendicectomy (laparoscopic preferred) within 24 hours; emergency if perforated/abscess
Acute Cholecystitis / Cholangitis
- IV fluids + analgesia
- Antibiotics: piperacillin-tazobactam or ceftriaxone + metronidazole
- Laparoscopic cholecystectomy within 72 h (acute cholecystitis) OR ERCP + sphincterotomy (choledocholithiasis/cholangitis)
- ERCP within 24 h for ascending cholangitis (Charcot's triad: fever + jaundice + RUQ pain); urgent if Reynold's pentad (add confusion + shock)
(Bailey & Love's Short Practice of Surgery, 28th Ed.; Current Surgical Therapy, 14th Ed.)
12. DENTAL EMERGENCIES
12A. Dental Abscess / Dentoalveolar Infection
- Examine for fluctuant swelling (intra- or extraoral)
- Incision and drainage (I&D): local anaesthesia, stab incision at most fluctuant point, blunt dissection, irrigate with saline, place corrugated drain 24-48 h
- Antibiotics: amoxicillin 500 mg TID for 5 days; amoxicillin-clavulanate if severe/mixed flora; clindamycin if penicillin-allergic
- URGENT referral to ENT/surgery if Ludwig's angina (bilateral submandibular space infection) - life-threatening airway emergency requiring early intubation/tracheostomy + IV antibiotics + surgical drainage
12B. Tooth Avulsion (complete dental displacement)
Time is critical - replant within 30 minutes for best prognosis.
- Handle tooth by crown only (never touch root)
- Rinse gently with saline or milk (do NOT scrub)
- Storage: replant immediately or keep in cold milk, saline, or patient's buccal vestibule (saliva) if transport needed
- Replant and stabilize with flexible splint for 7-14 days
- Root canal treatment within 7-10 days (unless tooth is immature/open apex)
- Refer to dentist/oral surgeon immediately
12C. Dental Fractures (Ellis Classification)
| Class | Extent | Emergency Treatment |
|---|
| Ellis I | Enamel only | Smooth sharp edges; elective dental referral |
| Ellis II | Enamel + dentine (yellow tinge, sensitive) | Calcium hydroxide dressing; dental referral within 24 h |
| Ellis III | Enamel + dentine + pulp exposure (pink/bleeding) | Emergency pulp capping or pulpotomy; immediate dental referral |
(Roberts and Hedges' Clinical Procedures in Emergency Medicine; Tintinalli's Emergency Medicine)
13. OBSTETRIC EMERGENCIES
Eclampsia
- Left lateral position; supplemental O2
- Protect airway; call obstetric + anaesthesia teams
- Magnesium sulfate: 4 g IV loading dose over 5-10 minutes; then 1-2 g/h IV maintenance (prevents and terminates eclamptic seizures)
- If seizure ongoing with Mg: lorazepam 4 mg IV
- Monitor: urine output (>25 mL/h), patellar reflexes (absent reflexes = Mg toxicity), respiratory rate
- Mg toxicity: calcium gluconate 1 g IV (antidote)
- Anti-hypertensives: labetalol IV or hydralazine IV to keep SBP <160 mmHg
- Definitive treatment: delivery of the fetus (consult obstetrics)
Postpartum Hemorrhage (PPH)
Definition: >500 mL blood loss vaginal delivery; >1000 mL Caesarean section
4 T's of causes: Tone (uterine atony 80%), Trauma, Tissue (retained placenta), Thrombin (coagulopathy)
- Bimanual uterine massage
- Oxytocin 10 IU IM or 5 IU slow IV; then oxytocin infusion 20 IU in 500 mL NS at 125 mL/h
- Ergometrine 0.25 mg IM (avoid in hypertension)
- Carboprost (15-methyl PGF2α) 0.25 mg IM every 15-90 min (max 8 doses); avoid in asthma
- Misoprostol 800-1000 mcg rectal/sublingual
- IV fluids + blood transfusion; massive transfusion protocol if massive hemorrhage
- Balloon tamponade (Bakri balloon or Sengstaken-Blakemore tube)
- Surgical options: B-Lynch suture, uterine artery ligation, emergency hysterectomy
Emergency Childbirth (Precipitate Delivery)
- Assist crowning with gentle pressure to control head delivery
- Check for nuchal cord (loop over head or clamp and cut)
- Allow natural restitution and external rotation
- Deliver anterior shoulder with gentle downward traction, then posterior shoulder upward
- Support and deliver the body; clamp and cut cord after pulsations cease
- Dry and stimulate the newborn; assess breathing and tone
- Await placenta (up to 30 min); never forcibly tug the cord
(Roberts and Hedges' Clinical Procedures in Emergency Medicine, 7th Ed.)
14. POISONING / OVERDOSE
General Approach (ABCDE + toxidrome recognition)
Step 1 - Stabilize
- Airway management (risk of vomiting and aspiration); intubate if GCS ≤8
- IV access; ECG (QRS and QTc prolongation are ominous)
- Blood: glucose, BMP, LFTs, ABG, CBC, toxicology screen, specific drug levels
Step 2 - Toxidrome identification
| Toxidrome | Features | Common Agents |
|---|
| Sympathomimetic | Tachycardia, hypertension, mydriasis, agitation, hyperthermia | Cocaine, amphetamines |
| Opioid | Miosis, bradypnea, coma, reduced tone | Morphine, heroin, fentanyl |
| Cholinergic | SLUDGE (Salivation, Lacrimation, Urination, Diarrhoea, GI cramps, Emesis) + bradycardia | Organophosphates, nerve agents |
| Anticholinergic | Dry-hot-flushed skin, mydriasis, urinary retention, delirium | Atropine, antihistamines, TCAs |
| Sedative/Hypnotic | CNS depression, respiratory depression | Benzodiazepines, barbiturates |
Step 3 - Decontamination
- Activated charcoal 50 g orally (adults): only if airway protected, within 1-2 h of ingestion, substance adsorbs to charcoal; NOT for hydrocarbons, metals, acids/alkalis
- Gastric lavage: rarely indicated; reserved for life-threatening ingestion within 1 hour; protect airway first
- Whole bowel irrigation (polyethylene glycol): for body packers, iron, lithium, sustained-release preparations
Step 4 - Antidotes
| Poison | Antidote | Dose |
|---|
| Opioids | Naloxone | 0.4-2 mg IV/IM/IN; repeat every 2-3 min; infusion for long-acting opioids |
| Benzodiazepines | Flumazenil | 0.2 mg IV over 30s; repeat to max 1 mg (caution: may precipitate seizures in chronic BZD users) |
| Paracetamol (acetaminophen) | N-acetylcysteine (NAC) | 150 mg/kg IV over 60 min, then 50 mg/kg over 4 h, then 100 mg/kg over 16 h |
| Organophosphates | Atropine + Pralidoxime | Atropine 2-4 mg IV every 5-10 min until secretions dry; pralidoxime 1-2 g IV over 15-30 min |
| TCA overdose | Sodium bicarbonate | 1-2 mEq/kg IV bolus for QRS >100 ms or arrhythmia; target blood pH 7.45-7.55 |
| Beta-blocker overdose | Glucagon | 3-5 mg IV bolus; then 2-5 mg/h infusion |
| Digoxin | Digoxin-specific Fab antibody fragments | Dose based on estimated digoxin load |
| Warfarin / Vitamin K antagonist | Vitamin K + 4-factor PCC or FFP | Vitamin K 5-10 mg IV slowly; PCC 25-50 IU/kg for urgent reversal |
| Heparin | Protamine sulfate | 1 mg per 100 units heparin administered, max 50 mg IV over 10 min |
| Iron | Deferoxamine | 15 mg/kg/h IV (for serum iron >500 mcg/dL or systemic toxicity) |
| Cyanide | Hydroxocobalamin | 5 g IV over 15 min (or sodium thiosulfate + sodium nitrite if Cyanokit unavailable) |
| Methanol / Ethylene glycol | Fomepizole (4-MP) | 15 mg/kg IV loading; then 10 mg/kg every 12 h (or ethanol infusion if fomepizole unavailable) |
| Carbon monoxide | 100% O2 (NRB) | High-flow 100% O2; hyperbaric O2 if severe (syncope, neurological changes, pregnancy) |
Summary Quick-Reference Table
| Emergency | Priority Action | Key Drug/Intervention |
|---|
| Cardiac Arrest | CPR + defibrillate VF | Adrenaline 1 mg IV every 3-5 min; Amiodarone 300 mg for refractory VF |
| Anaphylaxis | Epinephrine IM thigh | 0.3-0.5 mg IM; repeat in 5-10 min |
| Septic Shock | Antibiotics + fluids | IV antibiotics within 1 h; 30 mL/kg crystalloid; norepinephrine for MAP <65 |
| Ischemic Stroke | tPA within 4.5 h | Alteplase 0.9 mg/kg IV; thrombectomy for LVO |
| STEMI | Emergent PCI | Aspirin + P2Y12 inhibitor; door-to-balloon ≤90 min |
| Status Epilepticus | Benzodiazepine | Lorazepam 4 mg IV; escalate to fosphenytoin/valproate |
| DKA | Fluids then insulin | NS 1 L bolus; Regular insulin 0.1 units/kg/h; K+ replacement |
| Hypertensive Emergency | Controlled BP reduction | Labetalol/Nicardipine IV; reduce MAP by ≤25% in first hour |
| Tension Pneumothorax | Needle decompression | 14G cannula 2nd ICS MCL; then chest tube |
| Opioid Overdose | Naloxone | 0.4-2 mg IV/IM/IN; repeat as needed |
| Eclampsia | Magnesium sulfate | 4 g IV load; 1-2 g/h maintenance; delivery is definitive |
| PPH | Oxytocin | Oxytocin 10 IU IM; escalate through uterotonic ladder |
Note: Drug doses given are for average adult patients. Always verify against local formulary, current guidelines, and patient-specific factors (weight, renal function, allergies, comorbidities) before administration. Pediatric dosing requires weight-based calculations and specialist input.