Here is a comprehensive overview of Tracheal Reconstruction:
Tracheal Reconstruction
Anatomy Relevant to Surgery
The adult trachea is approximately 11 cm long (range 10-13 cm) and contains 14-20 tracheal rings. With neck hyperextension, about 50% of the trachea is cervical. The blood supply enters laterally in a segmental pattern - this is critical to preserve during dissection. The recurrent laryngeal nerves lie in the tracheoesophageal groove bilaterally and enter the larynx just medial to the inferior cornua of the thyroid cartilages.
Importantly, approximately 50% of the tracheal length (5-7 cm) can be safely resected and anastomosed primarily with appropriate mobilization - Cummings Otolaryngology, Ch. 112.
Surgical Access by Level
| Tracheal Location | Approach |
|---|
| Cervical & upper 2/3 intrathoracic | Low collar (transverse cervical) incision ± partial sternotomy |
| Lower 1/3 intrathoracic | Right posterolateral thoracotomy (4th ICS) |
| Carina | Median sternotomy (preferred for exposure) |
| Extended access (mid-trachea) | T-shaped incision with vertical arm to angle of Louis + partial manubrium division |
The partial upper sternotomy (not full sternotomy) is preferred because the carina lies at the level of the angle of Louis - full sternotomy adds no useful exposure while the great vessels obstruct the view. - Current Surgical Therapy 14e
Tracheal Resection and Primary Anastomosis
This is the gold standard for both benign stenosis and resectable tracheal tumors.
Patient Positioning
- Supine with inflatable pad beneath shoulders to extend the neck maximally
- The pad is deflated after resection to allow neck flexion for a tension-free anastomosis
Key Intraoperative Steps
- Subplatysmal flaps developed superiorly to thyroid cartilage, inferiorly to clavicular heads
- Strap muscles separated in midline; thyroid isthmus divided and retracted
- Tracheal mobilization - dissection kept immediately adjacent to the tracheal wall (preserves recurrent laryngeal nerves and lateral blood supply)
- Lesion localization - intraoperative bronchoscopy + 25-gauge needle through the tracheal wall at the upper and lower extents of the stenosis
- Stay sutures placed in proximal and distal ends before division to assist alignment and gauge tension
- Distal airway management - proximal ETT withdrawn; sterile armored ETT placed in distal trachea across the surgical field for ventilation during resection
- Frozen section of resection margins (especially for malignant tumors)
Anastomosis Technique
- Posterior membranous wall: continuous running absorbable suture
- Anterior cartilaginous wall: interrupted simple absorbable sutures (e.g., 4-0 Vicryl) placed circumferentially, every 5 mm, knots tied outside the lumen
- Sutures are placed through the cartilage ~4 mm from the cut edge and 4 mm apart
- Anastomosis tested by insufflation to 20-30 cm H₂O while submerged in saline - must be completely airtight
Wound Closure
- Sternohyoid muscle or thyroid isthmus used to cover and buttress all suture lines
- If innominate artery was dissected, a pedicled strap muscle flap is interposed between the artery and trachea
- Flat suction drains placed in pretracheal and substernal spaces
Tension Reduction: Mobilization Maneuvers
Anastomotic tension is the single most important technical factor determining outcome. Several progressive maneuvers are used:
| Maneuver | Additional Length Gained |
|---|
| Neck flexion (deflate shoulder pad) | Significant - initial step |
| Cervical approach + tracheal mobilization | 4-5 cm total |
| Montgomery suprahyoid release | ~1-2 cm |
| Right hilar release (U-incision around inferior pulmonary vein + pericardial incision) | ~1 cm additional |
Montgomery Suprahyoid Release
The muscles inserting on the superior aspect of the hyoid (between the lesser cornua) are divided. The hyoid bone is then divided just lateral to the lesser cornu on both sides. This detaches the hyoid from the skull base musculature and allows the larynx to descend, gaining 1-2 cm of extra tracheal mobility. - Current Surgical Therapy 14e
Guardian (Chin-to-Chest) Stitch
After closure, a heavy suture is placed from the submental skin crease to the presternal skin, tying with the neck in moderate flexion. This prevents sudden neck hyperextension in the first postoperative week, which would place stress on the fresh anastomosis. Hyperflexion must be avoided as it can cause spinal cord ischemia and quadriplegia. - Current Surgical Therapy 14e
Illustration of the trachea and carina
Subglottic / Cricoid Involvement
When stenosis involves the cricoid:
- Anterior-only involvement: anterior cricoid arch resected, distal trachea beveled to match the defect - recurrent laryngeal nerves are spared
- Circumferential involvement: may require laryngectomy, or the oblique cricoid resection (Pearson technique): resection line begins anteriorly at the inferior thyroid cartilage border and passes posteriorly below the cricoid plate, below the recurrent nerve entry point; the distal trachea is "telescoped" in front of the residual cricoid shell (thyrotracheal anastomosis)
- In pediatric CTR (cricotracheal resection): laryngeal release is usually not required - Scott-Brown's Otorhinolaryngology
Carinal Resection and Reconstruction
Carinal resection is technically the most demanding form of tracheal surgery. Tumors involving more than 4 cm of tracheal length generally preclude resection.
Options for reconstruction (described by Grillo, 1982):
- Carinal restitution (for small/central tumors only): medial walls of right and left mainstem bronchi are approximated to create a neo-carina, then anastomosed to the distal trachea
- Standard carinal reconstruction (most common): trachea anastomosed end-to-end to one mainstem bronchus (usually left); the other bronchus anastomosed to the lateral wall of the trachea above the first anastomosis
- The left mainstem bronchus is relatively fixed by the aorta, limiting approximation - this is why most carinal reconstructions are right-sided approaches
Postoperative Management
- Extubation in the OR is preferred after tracheal resection
- If airway is unsatisfactory: small ETT with cuff deflated left for 24-48 hours, with IV dexamethasone (4 mg q6h), diuretics, fluid restriction, head elevation to reduce laryngeal edema
- Re-examine under anesthesia at 48 hours; if still problematic, a small tracheostomy tube placed 2 rings below the anastomosis (not through it)
- Contraindications to repair (Sabiston): (1) inadequately treated laryngeal problem; (2) need for permanent ventilatory support (ALS, myasthenia gravis, quadriplegia); (3) high-dose steroids; (4) inflamed/recent tracheostomy
Tracheal Substitutes (When Primary Anastomosis Is Not Possible)
Four approaches exist, all facing the challenge of restoring blood supply and mucociliary barrier function - Cummings Otolaryngology, Ch. 112:
| Approach | Key Features | Limitations |
|---|
| Allotransplantation | Donor trachea revascularized via forearm flap, then orthotopically transplanted | Prolonged 2-stage process; long-term immunosuppression needed; not suitable for malignancy |
| Autologous tissue | Tubularized vascularized pedicle flap from another site | No immunosuppression needed; built-in blood supply; but cartilaginous rigidity difficult to replicate |
| Bioprosthesis | Marlex mesh, Dacron, silicone | Historical; non-porous materials doomed to failure due to infection and poor integration |
| Tissue engineering | Stem cell-seeded scaffolds (cadaveric or synthetic nanocomposite) | Promising early cases reported; revascularization within 1 week; still experimental |
The published literature shows that nonbiologic prostheses uniformly fail due to the fragile segmental blood supply and high infection risk. Allotransplantation is considered most promising for true replacement but is limited by immunosuppression requirements. - Fischer's Mastery of Surgery, Ch. on Carinal Resection
Contraindications to Surgical Resection (Tracheal Tumors)
- Invasion of critical mediastinal structures (aorta, esophagus, superior vena cava)
- Tumor involving an extensive tracheal length precluding tension-free anastomosis
- Bilateral recurrent laryngeal nerve sacrifice (requires permanent tracheostomy)
- Poor functional status / inability to undergo major surgery
Palliative / Endoscopic Options for Unresectable Disease
When surgical resection is not feasible, the following bronchoscopic/endoscopic techniques offer palliation:
- Dilation (bougie or balloon) - temporizing only
- Rigid bronchoscopic debridement / coring out
- Nd:YAG laser vaporization - best for pedunculated, vascular tumors; can be done through flexible scope under topical anesthesia
- Photodynamic therapy (PDT) - useful for circumferential or submucosal tumors
- Cryotherapy
- Brachytherapy
- Tracheal stenting (Dumon or Montgomery T-tube) - maintains lumen, especially in long-segment or subglottic stenosis
Outcomes
- For benign stenosis (post-intubation): success rates >90% with segmental resection and primary anastomosis - Cummings Otolaryngology
- Primary tracheal malignancies: surgical resection with primary anastomosis is the therapy of choice when feasible; adenoid cystic carcinoma and squamous cell carcinoma are the two most common types
- Subglottic involvement and impaired vocal cord movement are associated with poorer outcomes
- Anastomotic complications (dehiscence, restenosis) are the most feared postoperative problems and are directly related to anastomotic tension and devascularization