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Calcfrol aq 6lac units. I took this shot today at my gluts right. Now my whole that leg is paining especially the site I had vitamin d 6 that's why Dr prescribed me this

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vitamin D3 injection gluteal muscle sciatic nerve pain leg after injection

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"sciatic nerve" AND intramuscular injection injury

Calcirol (cholecalciferol) 6 lakh IU is a thick, oily depot injection given deep IM into the buttock. What you're describing - pain at the injection site spreading down the whole leg - is a recognized issue with gluteal injections, and it's worth taking seriously rather than just waiting it out. There are two main possibilities:
1. Simple post-injection muscle soreness (most common, benign) High-dose vitamin D depot injections are viscous/oily and often cause local muscle irritation, mild inflammation, or a small sterile reaction at the injection site. This typically causes:
  • Soreness/ache localized mainly around the injection site
  • Mild stiffness when sitting, walking, or lying on that side
  • Gradual improvement over 2-4 days
2. Sciatic nerve irritation/injury (less common, but important to rule out) The gluteal region overlies the sciatic nerve, and if the injection is placed even slightly off from the correct site (upper-outer quadrant of the buttock), the needle can irritate or directly injure the nerve. This is a well-documented complication of gluteal intramuscular injections - textbooks note that "serious sciatic nerve injury can result from improperly performed injections into the buttocks," with older age and low muscle mass being risk factors (Andrews' Diseases of the Skin, p. 79; Campbell's Operative Orthopaedics). Pain that radiates the entire length of the leg (not just local soreness) raises this possibility, especially if you also notice:
  • Numbness, tingling, or "electric shock" sensations down the leg or into the foot
  • Weakness - especially difficulty lifting your foot upward (foot drop) or curling your toes
  • Burning or shooting pain radiating to the calf/foot
  • Skin over the leg becoming unusually shiny, cold, or losing sweating
  • Loss of sensation on the outer leg or sole of the foot
What to do now
  • If it's just soreness without any numbness, tingling, or weakness: a warm compress, gentle movement (avoid prolonged sitting on that side), and a paracetamol-based analgesic is usually enough, and it should ease within a few days.
  • If you notice ANY numbness, tingling, weakness, or difficulty moving your foot/toes, or if the pain is severe/shooting rather than a dull ache, contact the doctor who gave the injection today - this needs prompt evaluation. Early recognition and treatment of injection-related sciatic nerve injury gives the best chance of full recovery; delayed care is associated with worse outcomes.
  • Avoid getting any further injections in that same buttock until it's checked.
I can't examine you, so I can't tell you which of these is happening - but given that the pain has spread down the entire leg (not just stayed local), I'd lean toward getting it checked by your doctor within the next day rather than waiting it out, just to rule out nerve involvement. Please don't ignore any weakness or numbness if it develops.
Is the pain a dull soreness, or does it feel sharp/shooting/burning down the leg? And have you noticed any numbness, tingling, or weakness in your foot or toes?

Today there is a little relief in pain but today also I am having difficulty in walking as I walk the site of injection pain. And after the injection I checked that there was no blood on cotton. Today no pain on full leg just on site and continuous pain

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localized pain after IM injection days later difficulty walking site tenderness sterile abscess vitamin D injection

This is a good sign - things are improving. Let me break down what's happening.
Why this pattern makes sense
The fact that pain no longer radiates down the whole leg and is now confined to the injection site itself is reassuring. This pattern fits a local muscle/soft-tissue reaction rather than ongoing sciatic nerve damage:
  • Calcirol is an oil-based depot injection. Oil-based IM injections commonly cause localized muscle irritation, mild sterile inflammation, and sometimes a small tender lump at the site - this is a recognized, expected side effect, not a sign of nerve injury.
  • The "no blood on cotton" observation isn't something to worry about either way - checking for blood (aspiration) before injecting is done by the person giving the injection to make sure they haven't hit a blood vessel. What you noticed on the cotton swab afterward doesn't tell you anything about nerve involvement; it's unrelated to the pain you're having.
  • Difficulty walking because movement pulls on the sore, inflamed muscle at the injection site is very common and expected for a day or two after a deep gluteal injection - it's different from difficulty walking due to weakness/foot drop (which would suggest nerve involvement).
What your current symptoms suggest
Continuous, localized pain right at the injection site, worse with walking, improving day over day = typical post-injection intramuscular soreness/mild sterile inflammation. This usually peaks in the first 24-48 hours and settles over 3-7 days.
Watch for these and contact your doctor if they appear:
  • Increasing redness, warmth, or swelling at the site (could mean infection or abscess forming)
  • The area becoming fluctuant/soft like a lump filled with fluid, or any discharge/pus
  • Fever or feeling generally unwell
  • Return of pain, numbness, or tingling spreading down the leg
  • No improvement at all after 5-7 days, or pain getting worse instead of better
What you can do now
  • Warm compress over the site a few times a day - helps with muscle soreness and local inflammation
  • Gentle movement/walking as tolerated rather than complete rest, but don't force through sharp pain
  • Avoid lying directly on that side or pressing on the area
  • Paracetamol if needed for pain
  • Avoid any further injections in that same spot until it settles
Since you're already trending better each day (whole-leg pain gone, now just site pain), this looks like normal post-injection muscle soreness settling down. If it hasn't substantially improved in the next 2-3 days, or if you notice any redness/swelling/fever, get it checked by the doctor who prescribed the injection.
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