Here is a complete overview of the extraocular (oculogeric) muscles, sourced from Neuroanatomy through Clinical Cases, 3rd Edition.
Extraocular (Oculomotor) Muscles
These are the six striated muscles that move each eyeball within the orbit. They also include the levator palpebrae superioris (not strictly an extraocular muscle but closely associated).
All six muscles originate from the common tendinous ring (annulus of Zinn) at the orbital apex, except:
- The inferior oblique - originates from the anterior medial orbital wall
- The superior oblique - originates from the sphenoid bone in the posterior medial orbit
The Six Extraocular Muscles
| Muscle | Primary Action | Secondary Action | Innervation |
|---|
| Lateral rectus | Abduction (temporal gaze) | - | CN VI (Abducens) |
| Medial rectus | Adduction (nasal gaze) | - | CN III (Oculomotor) |
| Superior rectus | Elevation | Intorsion | CN III (Oculomotor) |
| Inferior rectus | Depression | Extorsion | CN III (Oculomotor) |
| Superior oblique | Depression + Intorsion | (depression increases with adduction) | CN IV (Trochlear) |
| Inferior oblique | Elevation + Extorsion | (elevation increases with adduction) | CN III (Oculomotor) |
Mnemonic - LR6SO4 (rest CN3): Lateral Rectus = CN VI, Superior Oblique = CN IV, all others = CN III.
Diagram - Rectus Muscles and Their Actions
Neuroanatomy through Clinical Cases, Fig. 13.1A - Rectus muscles
Oblique Muscles - Special Features
The obliques produce torsional movements (rotation of the eye about its axis):
- Superior oblique passes through the trochlea (a fibrous pulley on the medial superior orbital rim), then curves back to insert on the superior surface of the globe. It produces intorsion (upper pole of eye rotates inward/nasally).
- Inferior oblique has no trochlea. It inserts on the inferior surface of the globe and produces extorsion (upper pole of eye rotates outward/temporally).
Neuroanatomy through Clinical Cases, Fig. 13.1C - Dual actions of superior rectus
Innervating Nerves and Their Paths
All three cranial nerves (CN III, IV, VI) travel through the cavernous sinus and enter the orbit via the superior orbital fissure.
CN III (Oculomotor) splits into two divisions in the orbit:
- Superior division - superior rectus + levator palpebrae superioris
- Inferior division - medial rectus, inferior rectus, inferior oblique + preganglionic parasympathetic fibers to the pupillary constrictor and ciliary muscle
CN IV (Trochlear) - exits the brainstem dorsally (unique among cranial nerves), crosses the midline, and innervates the contralateral superior oblique.
CN VI (Abducens) - long intracranial course; innervates the lateral rectus.
Brainstem Nuclei
| Nerve | Nucleus Location |
|---|
| CN III | Upper midbrain, level of superior colliculi, ventral to periaqueductal gray |
| CN IV | Lower midbrain, level of inferior colliculi |
| CN VI | Pons (near the floor of the 4th ventricle) |
The Edinger-Westphal nucleus sits dorsal to the CN III nucleus and carries preganglionic parasympathetics for pupil constriction and lens accommodation.
Additional Eye Muscles (Not Strictly Extraocular)
| Muscle | Action | Innervation |
|---|
| Levator palpebrae superioris | Elevates upper eyelid | CN III (superior division) |
| Pupillary constrictor | Miosis | CN III (parasympathetic via ciliary ganglion) |
| Pupillary dilator | Mydriasis | Sympathetic (superior cervical ganglion) |
| Ciliary muscle | Lens accommodation (thickens lens) | CN III (parasympathetic) |
Clinical Pearls
| CN | Palsy Findings |
|---|
| CN III palsy | "Down and out" eye (unopposed lateral rectus + superior oblique), ptosis, fixed dilated pupil (if nerve compressed - e.g., PCA aneurysm) |
| CN IV palsy | Vertical diplopia, eye excyclotorted; patient tilts head to compensate; causes difficulty descending stairs |
| CN VI palsy | Medial deviation of eye (esotropia), inability to abduct; most common CN palsy; can be a false localizing sign in raised ICP |
Sources: Neuroanatomy through Clinical Cases, 3rd Edition (9781605359625)