Generate high yield, difficult and some of them as clinical mcqs for 1st year mbbs for physiology. Reference book is guyton physiology ch9 and 10 and following are the LOs. Explain the physiological anatomy of cardiac muscle. Explain the functional importance of intercalated discs. Discuss the properties of cardiac muscles. Describe and draw the phases of action potential of ventricle. Describe and draw the phases of action potential of SA node along with explanation of the mechanism of self- excitation/ Auto rhythmicity of SA node. Define and give the duration of the Absolute and relative refractory period in cardiac muscle. Describe the mechanism of excitation-contraction coupling and relaxation in cardiac muscle. Describe the Frank starling mechanism. Describe the autonomic regulation of heart pumping. Describe the effect of potassium, calcium ions & temperature on heart function. Define chronotropic effect- positive and negative. 114 C2K23 Year-01 TOTAL HOURS = 68 DISCIPLINE TOPIC Physiology Cardiac Muscle Integrate with Medicine Physiology Regulation of heart pumping CV-P-003 CV-P-004 CV-P- 005 Define the inotropic effect: positive and negative. Define dromotropic effect: positive and negative Describe the location of adrenergic & cholinergic receptors in heart. Name the receptors present in coronary arterioles. Explain sympathetic & parasympathetic effects on heart rate & conduction velocity Draw and explain the conducting system of heart Describe the physiological basis and significance of AV nodal delay.