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how to search for the given topic in prospero Impact of anastomotic leakage on long-term oncological outcomes after colorectal cancer resection: an updated systematic review and meta-analysis

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PROSPERO search anastomotic leakage colorectal cancer long-term oncological outcomes systematic review

Searching the Web

how to search PROSPERO register systematic review site:crd.york.ac.uk OR prospero.nihr.ac.uk

Here is a complete step-by-step guide to searching PROSPERO for your topic, plus what the search found.

How to Search PROSPERO for Your Topic

Step 1 - Go to the PROSPERO Search Page

Navigate to prospero.nihr.ac.uk/search directly. You do not need to log in to search - only to register.

Step 2 - Enter Your Search Terms

Do not paste the entire title into the search box. PROSPERO's search works best with focused keyword combinations. Use these strategies:
Option A - Simple keyword search (start here):
anastomotic leakage colorectal cancer oncological outcomes
Option B - Boolean search (more precise):
anastomotic leakage AND colorectal AND (recurrence OR survival OR oncological)
Option C - Using field tags (title-specific search):
TI:(anastomotic leakage) AND TI:(colorectal cancer)
The TI: prefix restricts the search to the Title field only.
Option D - Proximity search (PROSPERO-specific syntax):
anastomotic NEAR leakage AND colorectal NEAR cancer
NEAR finds terms within 6 words of each other by default. You can specify distance: anastomotic NEAR/3 leakage.
Option E - Wildcard search:
anastomot* AND colorectal AND oncolog*
The * wildcard captures variations (anastomotic/anastomosis, oncological/oncology).

Step 3 - Apply Filters (Optional but Recommended)

After your initial results appear, use the left-hand filter panel to narrow by:
  • Status: Registered, Ongoing, Completed
  • Date registered: Narrow to recent years (e.g., 2022-2026) for an "updated" review
  • Country: If you know the team's country

Step 4 - Scan Results

For your specific topic, look for records mentioning:
  • Anastomotic leak / anastomotic leakage
  • Colorectal cancer / rectal cancer / colon cancer
  • Long-term outcomes / oncological outcomes / recurrence / survival
  • Meta-analysis / systematic review
Note: A closely related record already exists - CRD420251086833 - registered July 2025, covering anastomotic leakage and colorectal outcomes. You should check whether this overlaps significantly with your planned review.

Step 5 - Check for Duplicates (Key Purpose of Searching)

If you are planning to register your own review, PROSPERO requires you to confirm no identical review is already registered. If you find a closely similar record, you must:
  1. Read the registered protocol carefully
  2. Determine if your review has a meaningfully different scope (e.g., updated date range, different outcomes, broader population)
  3. State clearly in your registration how your review differs

Step 6 - Register Your Review (If No Duplicate Found)

  1. Create a PROSPERO account (free)
  2. Click "Register a new review"
  3. Fill in the structured form: title, objectives, PICO elements, search strategy, databases, outcome measures, etc.
  4. Submit - PROSPERO will assign a CRD number you can cite in your manuscript

Recommended Search String for Your Exact Topic

Given your title - "Impact of anastomotic leakage on long-term oncological outcomes after colorectal cancer resection" - the most targeted PROSPERO search would be:
anastomotic leakage AND colorectal AND (long-term OR oncolog* OR recurrence OR survival OR prognosis)
Or even more focused:
TI:anastomotic AND TI:colorectal AND TI:oncolog*
This will surface any registered or ongoing reviews with those terms in the title, helping you confirm your review is genuinely novel or an authorized update of a prior one.
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