Question 2 - Short Notes
A. Management of Premature Rupture of Membranes
Premature Rupture of Membranes (PROM) is leakage of amniotic fluid before onset of labour. At term (37 weeks or beyond), labour begins spontaneously in most women within 24 hours; if not, induction is recommended to reduce infection risk. Diagnosis is confirmed by nitrazine test (alkaline pH of amniotic fluid turns paper blue), ferning pattern on microscopy, or pooling of fluid in the vagina. Preterm PROM (before 37 weeks) is managed conservatively with bed rest, broad-spectrum antibiotics (erythromycin/ampicillin) to prolong latency and reduce chorioamnionitis, corticosteroids for fetal lung maturity (betamethasone before 34 weeks), and tocolytics if needed. Delivery is indicated when infection (chorioamnionitis), fetal distress, or cord prolapse occurs. The main maternal risk is intrauterine infection; the main fetal risk is prematurity and sepsis.
B. External Cephalic Version
External Cephalic Version (ECV) is a procedure to convert a breech or transverse presentation to a vertex presentation before labour. It is performed at 36-37 weeks gestation. A tocolytic (terbutaline) is given to relax the uterus. The clinician applies firm, steady pressure on the maternal abdomen to rotate the fetus. Success rate is approximately 50-60%. Neuraxial (spinal or epidural) anaesthesia improves success rates. Continuous fetal heart rate monitoring is done before and after the procedure. Contraindications include uterine anomalies, placenta praevia, oligohydramnios, previous uterine surgery, multiple gestation, non-reassuring fetal heart rate, and ruptured membranes. Complications include placental abruption, cord prolapse, fetomaternal haemorrhage, and premature labour. Anti-D immunoglobulin is given to Rhesus-negative mothers after the procedure.
C. Partograph
A partograph is a graphical record of labour progress used to detect abnormal labour early. It records cervical dilatation (plotted against time), descent of the fetal head, uterine contractions (frequency, duration, strength), fetal heart rate, membranes and liquor status, moulding, maternal vital signs, and drugs given. The World Health Organisation partograph has an alert line and an action line drawn 4 hours to its right. When cervical dilatation crosses the alert line, transfer to a higher facility is advised. When it crosses the action line, active intervention (augmentation or operative delivery) is required. The partograph helps reduce prolonged labour, obstructed labour, postpartum haemorrhage, uterine rupture, and perinatal asphyxia. It is a simple, cost-effective tool proven to improve obstetric outcomes worldwide.
D. Intrauterine Growth Restriction
Intrauterine Growth Restriction (IUGR) refers to a fetus that fails to achieve its genetically determined growth potential and has an estimated fetal weight below the 10th percentile for gestational age. It is classified as symmetric (affects head and body equally - suggests early insult such as infection or chromosomal anomaly) and asymmetric (head-sparing - suggests late uteroplacental insufficiency). Causes include maternal factors (hypertension, diabetes, anaemia, smoking), placental factors (insufficiency, infarction), and fetal factors (chromosomal anomalies, infections). Diagnosis is by serial ultrasound measurements and Doppler flow studies of the umbilical artery. Absent or reversed end-diastolic flow indicates severe compromise. Management involves treating the cause, fetal surveillance (Doppler, biophysical profile), and timely delivery. Complications include perinatal asphyxia, hypoglycaemia, hypothermia, and long-term neurodevelopmental delay.
Question 3 - Very Short Notes
1. Bishop Score
The Bishop Score is a pre-labour cervical assessment system used to predict the likelihood of successful induction of labour. It evaluates five parameters: cervical dilatation (0-3), effacement (0-3), consistency (0-2), position (0-2), and station of the presenting part (0-3), giving a maximum score of 13. A score of 9 or above is considered favourable; induction is likely to succeed without cervical ripening. A score of 6 or below indicates an unfavourable cervix; cervical ripening with prostaglandins (dinoprostone or misoprostol) or a balloon catheter is recommended before induction. The score helps clinicians decide the method and urgency of induction and counsel patients about the likely duration and success of labour induction.
2. Brow Presentation
Brow presentation is a type of cephalic malpresentation in which the fetal head is partially extended, with the brow (the area between the anterior fontanelle and the orbital ridges) as the presenting part. The presenting diameter is the mento-vertical diameter (approximately 13.5 centimetres), which is the largest head diameter and usually too large to engage in a normal pelvis. Most brow presentations convert spontaneously to either a vertex presentation (by flexion) or a face presentation (by further extension). If persistent at term, vaginal delivery is generally impossible and caesarean section is required. Causes include prematurity, polyhydramnios, fetal anomaly, or a large head. Diagnosis is confirmed on vaginal examination by feeling the anterior fontanelle and orbital ridges simultaneously.
3. Assisted Breech Delivery
Assisted breech delivery (also called partial breech extraction) is a method of vaginal delivery where the fetus delivers spontaneously up to the umbilicus and the attendant then assists delivery of the shoulders and head. The buttocks and trunk deliver by maternal effort. The legs are released by Pinard's manoeuvre (pressure behind the knee). The arms are delivered by Lovset's manoeuvre (rotating the trunk 180 degrees to bring each arm down). The after-coming head is delivered by the Mauriceau-Smellie-Veit manoeuvre (jaw flexion and shoulder traction) or forceps (Piper's forceps). It requires an experienced operator and a fully dilated cervix. Complications include cord prolapse, head entrapment, and birth asphyxia. It is now rarely performed due to the widespread preference for caesarean section for term breech.
4. Cervical Cerclage
Cervical cerclage is a surgical procedure in which a stitch (suture) is placed around the cervix to keep it closed during pregnancy, used primarily for cervical incompetence. Cervical incompetence presents as painless cervical dilatation and effacement in the second trimester, leading to recurrent mid-trimester pregnancy loss. The most common technique is the McDonald suture (purse-string suture at the cervico-vaginal junction). The Shirodkar technique is a buried suture placed at a higher level and requires dissection. The suture is placed between 12-14 weeks and removed at 36-37 weeks or when labour begins. Indications include a history of recurrent second trimester loss, short cervix on ultrasound (below 25 millimetres before 24 weeks), or cervical dilatation found on examination. Contraindications include active infection, ruptured membranes, and active bleeding.
5. Causes of Intrauterine Fetal Death
Intrauterine Fetal Death (IUFD) is the death of a fetus at or beyond 20 weeks of gestation (or weighing 500 grams or more) before delivery. Causes include: Fetal - chromosomal anomalies, congenital malformations, fetomaternal haemorrhage, fetal infections (parvovirus B19, cytomegalovirus, toxoplasmosis); Placental - placental abruption, placenta praevia, placental insufficiency, cord accidents (true knot, cord prolapse, tight nuchal cord, velamentous cord insertion); Maternal - diabetes mellitus, hypertensive disorders (pre-eclampsia), intrahepatic cholestasis of pregnancy, thrombophilias (antiphospholipid syndrome), anaemia, infections (malaria, syphilis); Unexplained - accounts for 25-50% of cases. Investigation includes post-mortem examination, placental histology, karyotyping, maternal blood tests (Kleihauer-Betke, TORCH serology, thrombophilia screen), and infection cultures.
6. Retained Placenta
Retained placenta is defined as failure of the placenta to deliver within 30 minutes of the baby's birth (active management) or 60 minutes (physiological management). Types include: adherent placenta (failed separation due to uterine atony), trapped placenta (separated but caught behind a closed cervical os), and morbidly adherent placenta (accreta, increta, percreta). Management includes ensuring the bladder is empty, controlled cord traction, and a trial of breastfeeding (to stimulate oxytocin). Intravenous oxytocin is given. If these fail, manual removal of placenta under regional or general anaesthesia is performed. Umbilical vein injection of saline with oxytocin can also be attempted. Complications include postpartum haemorrhage, uterine inversion, uterine perforation, and infection. Blood transfusion and hysterectomy may be required in severe cases.
7. Mechanism of Labour in Occipito-Anterior Position
The mechanism of labour describes the series of passive movements the fetus undergoes to navigate the birth canal. In the left or right occipito-anterior position, the seven cardinal movements are:
- Engagement - the widest diameter of the fetal head passes through the pelvic inlet
- Descent - progressive downward movement throughout labour
- Flexion - the chin meets the chest, reducing the presenting diameter from occipito-frontal to suboccipito-bregmatic (9.5 centimetres)
- Internal rotation - the occiput rotates anteriorly to lie under the symphysis pubis (the sagittal suture now runs in the antero-posterior diameter)
- Extension - the head extends as it passes under the symphysis pubis; the occiput, brow, face, and chin are born in succession
- Restitution - the head rotates back by 45 degrees to align with the shoulders
- External rotation - further rotation as shoulders engage; anterior shoulder delivers first, then posterior shoulder, then the rest of the body
8. Physiology of Lactation
Lactation involves two phases - milk production (galactopoiesis) and milk ejection. During pregnancy, high oestrogen and progesterone stimulate ductal and alveolar development in the breast but inhibit milk secretion. After delivery, the sudden fall in progesterone removes this inhibition. Prolactin (from the anterior pituitary), stimulated by infant suckling, drives milk synthesis in alveolar epithelial cells. Oxytocin (from the posterior pituitary), also released by suckling via a neuroendocrine reflex, contracts myoepithelial cells around the alveoli causing milk ejection (let-down reflex). Colostrum is secreted in the first few days - it is rich in immunoglobulin A, protein, and has laxative properties. Mature milk (foremilk and hindmilk) follows by day 3-5. Lactation suppresses ovulation by inhibiting gonadotropin-releasing hormone pulsatility - providing natural (but not absolute) contraception.
9. Uterine Inversion
Uterine inversion is a rare but life-threatening obstetric emergency where the uterine fundus collapses into or through the cervix. It is classified as incomplete (fundus inverts but remains above the cervix), complete (fundus protrudes through the cervix into the vagina), and prolapsed (uterus protrudes beyond the vaginal introitus). Causes include mismanagement of the third stage of labour - fundal pressure, excessive cord traction before placental separation, or an abnormally short cord. It presents with sudden severe postpartum haemorrhage, shock disproportionate to visible blood loss, and absence of the uterine fundus on abdominal palpation. Management: call for help, do NOT remove the placenta if still attached, give intravenous fluids and blood, attempt manual replacement immediately (Johnson's manoeuvre - pushing the fundus upward with the palm). Tocolytics (terbutaline, nitroglycerine) relax the cervical ring to aid replacement. Surgical correction (Huntington's or Haultain's procedure) is used if manual replacement fails.
10. Neonatal Resuscitation
Neonatal resuscitation is the immediate stabilisation of a newborn who fails to establish adequate breathing and circulation at birth. The sequence follows the mnemonic of Warmth, Airway, Breathing, Circulation. At birth, the baby is dried, stimulated, and assessed using the Apgar score at 1 and 5 minutes (scoring heart rate, respiratory effort, muscle tone, reflex response, and colour). If the baby is not breathing or gasping, the airway is cleared and positive pressure ventilation with a bag and mask using 21% oxygen is begun at 40-60 breaths per minute. If the heart rate remains below 60 beats per minute despite 30 seconds of effective ventilation, chest compressions are started at a 3:1 compression-to-ventilation ratio. Epinephrine (adrenaline) is given intravenously or via endotracheal tube if the heart rate remains below 60. Naloxone reverses narcotic-induced depression. Glucose is given for documented hypoglycaemia.
---All 13 topics have been answered above in 100-200 words each, without any short forms. Here is a quick reference to what was covered:
Question 2 - Short Notes (any 3 of 4):
- Management of Premature Rupture of Membranes
- External Cephalic Version
- Partograph
- Intrauterine Growth Restriction
Question 3 - Very Short Notes (any 9 of 10):
- Bishop Score
- Brow Presentation
- Assisted Breech Delivery
- Cervical Cerclage
- Causes of Intrauterine Fetal Death
- Retained Placenta
- Mechanism of Labour in Occipito-Anterior Position
- Physiology of Lactation
- Uterine Inversion
- Neonatal Resuscitation